The invention relates to the field of plant protection natural enemy insect breeding, and discloses a breeding method of harmonia axyridis, which comprises the stages of plant seedling preparation, aphid propagation, harmonia axyridis breeding and the like, the scheme adopts two modes of aphid independent propagation and aphid-harmonia axyridis coexistence propagation to propagate aphids, and food supply of harmonia axyridis in different growth stages is fully met; meanwhile, the mode of segmented feeding in different growth periods is adopted, and the growth habit and the growth period of the harmonia axyridis can be conveniently and accurately monitored. By adopting the scheme to breed the harmonia axyridis, the growth cycle of the harmonia axyridis can be effectively shortened, the method has the advantages of being simple in breeding method, mild in breeding condition, simple in breeding equipment, suitable for industrialized large-scale breeding and the like, the survival rate of the harmonia axyridis is high, and the method is suitable for large-scale breeding of the harmonia axyridis in various regions for biological control of aphids.