The invention provides a preparation process of
fat emulsion injection products and the
fat emulsion injection products, which are characterized in that the preparation process comprises the following steps of:
oil phase preparation; aqueous phase preparation; neogala preparation; high-pressure homogenization;
oxygen-free filling; and sterilization to prepare the
fat emulsion injection products, wherein in the aqueous phase preparation, an appropriate amount of water for injection,
glycerol and
sodium hydroxide are added into a preparation tank B, and the mixture is stirred and heated to the temperature of between 50 and 90 DEG C; the
sodium hydroxide is used for regulating pH values and forming
sodium aliphatate with
fatty acid; and before the sterilization, the pH values of the products are regulated to between 7.0 and 12.0, and the products are subjected to vacuumization and nitrogenization to prepare an aqueous phase. The preparation process of the fat
emulsion injection products can improve the stability of fat
emulsion, and have the advantages of simple process and convenient operation; and the phenomena of hyperoxide generated due to
oil oxidation or harmful substances such as
aldehyde,
ketone and the like which are generated due to the continuous
decomposition of the hyperoxide occurs rarely under the condition that auxiliary materials such as
antioxidant and the like are not added.