78 results about "CLASS AMPHIBIA" patented technology

In one aspect, the present invention relates to a mammalian cell-based high-throughput assay for the profiling and screening of human epithelial sodium channel (hENaC) cloned from a human kidney c-DNA library and is also expressed in other tissues including human taste tissue. The present invention further relates to amphibian oocyte-based medium-throughput electrophysiological assays for identifying human ENaC modulators, preferably ENaC enhancers. Compounds that modulate ENaC function in a cell-based ENaC assay are expected to affect salty taste in humans. The assays described herein have advantages over existing cellular expression systems. In the case of mammalian cells, such assays can be run in standard 96 or 384 well culture plates in high-throughput mode with enhanced assay results being achieved by the use of a compound that inhibits ENaC function, preferably an amiloride derivative such as Phenamil. In the case of the inventive oocyte electrophysiological assays (two-electrode voltage-clamp technique), these assays facilitate the identification of compounds which specifically modulate human ENaC. The assays of the invention provide a robust screen useful to detect compounds that facilitate (enhance) or inhibit hENaC function. Compounds that enhance or block human ENaC channel activity should thereby modulate salty taste in humans.

The amphibian rolling car comprises the outside wall and inner cavity, a frame of a cylinder and edge bracket of two sides, wall plate at the edge frame to form a sealed cabin, a slide plate cart inside the cavity rotating with the roller coaxially, ring track inside the frame with the slide plate on the ring track. The slide plate car is electric driving or driven, with simple structure, small size, elegant in shape, being able to use on road, square, grass and snow and even in water.

An amphibian (10) capable of travel on land and on water is provided with a body and a planing hull (12), and three road wheels (20, 24) mounted on retractable suspension (22, 26) which may be protracted for road use, or retracted for use on water; and further comprises ride-on seating for at least one driver to sit astride the body. Marine propulsion is provided by at least two jet drives (30), which have intakes (32) and nozzles (34). Picture 3 shows a power train and retractable rear wheel suspension. Steering control may be by handlebars (42), or by a steering wheel (not shown). The jets may be driven by belts and/or driveshafts. A separate power source may be provided for marine use. A windscreen (44) may be fitted.

A retractable land propulsion assembly for an amphibian including a retraction linkage movable between a protracted position and a retracted position, an actuator for moving the retraction linkage between the protracted position and retracted position, and at least one wheel and/or track drive. When the retraction linkage is protracted then the retraction linkage supports and/or holds the at least one wheel and/or track drive in a ground engaging position for use on land. The retraction linkage comprises at least one component or part or portion thereof that passes through an overcentre position on protraction to prevent forces received in use via the at least one wheel and/or track drive from acting to retract the retraction linkage.

The invention discloses an amphibian bicycle which aims to solve the problems that a floating device of an existing amphibian bicycle occupies a large space when the amphibian bicycle is ridden on the land and the amphibian bicycle can not be braked on the water. The amphibian bicycle comprises a front wheel assembly, a rear wheel assembly, a floating device, a frame, a driving mechanism and a steering mechanism, wherein the front wheel assembly and the rear wheel assembly are respectively of a hubless structure, the floating device is connected with the interior of the front wheel assembly and the interior of the rear wheel assembly and provided with a folding stretching arm, a gear transmission mechanism of the driving mechanism is connected with a propeller driving assembly through a flexible shaft connecting mechanism and fixed to the frame, the propeller driving assembly is fixedly connected with the rear wheel assembly, a control part of the steering mechanism is assembled on the frame, and an execution part of the steering mechanism is assembled on the propeller driving assembly of the driving mechanism and connected with the control part through a pull rope.

Planing amphibian (10) comprises hull (12) and a pair of wheels (20) mounted on a retractable suspension assembly (22). At least one land drive and at least one separate marine drive (40) are provided. A wheel retraction mechanism is provided for moving the wheels between a deployed wheel position for use of the amphibian on land and a retracted wheel position above a waterline of the amphibian for planing on water. The suspension assembly comprises suspension arms (24) outside the pair of wheels (20) so that the wheels (20) lie between the arms (24). Marine drives (40) may be inboard of the wheels or outboard thereof. An axle (28) with a differential (29) may be provided. Suspension and retraction may be provided by means of torsion bars (30) with a cranked central section (54, 55).

The invention relates to the technical field of environment monitoring equipment, in particular to an amphibian unmanned aerial vehicle environment monitoring device. The device comprises an unmannedaerial vehicle body and a controller arranged inside the unmanned aerial vehicle body for controlling the unmanned aerial vehicle, further comprises a floating mechanism arranged at the bottom of theunmanned aerial vehicle body and for enabling the unmanned aerial vehicle body to float on the water surface, a detecting mechanism for detecting the water quality and a sampling mechanism for sampling water to be detected, and the detecting mechanism and the sampling mechanism are arranged on the floating mechanism. The monitoring device performs detecting and sampling more flexibly in the mode of the unmanned aerial vehicle.

The present invention involves an edible terrarium substrate for a terrarium animal such as a reptile, an amphibian, or an arachnid. The substrate includes a fine calciferous sand that is healthy, ingestible, and digestible by the terrarium animal.

The invention relates to an amphibian bicycle, in particular to a bicycle capable of realizing water running function. The main devices capable of realizing water running function are as follows: a floating device, a connecting rod supporting device, a cushion and a front flywheel linkage lifting device, a tap adjusting device, a hub paddle wheel pick driving device and a front wheel steering device, wherein floating bodies take the shape of dumbbells and are fixed with the connecting rod supporting device and symmetrically mounted on the two sides of the bicycle. When the bicycle runs on the land, the floating body can be picked up by the connecting rod supporting device and is clung to the two sides of the bicycle, so as to realize land cycling function of general bicycles; when the bicycle runs on the water, the connecting rod support device can be put down and the floating body is placed on the water surface, and meanwhile, the cushion and the front flywheel can be elevated through the cushion and the front flywheel linkage lifting device, so that foot wet or cloth wet caused by water cycling can be avoid. Water running steering can be realized by treading pedals, controlling the tap by hand, and swing a front solid wheel.

The invention relates to a rana nigromaculata antimicrobial peptide as well as a gene and application thereof, and belongs to the technical field of biomedicine. The rana nigromaculata antimicrobial peptide is a gene coded single-chain polypeptide separated from an amphibian rana nigromaculata of China, wherein the molecular weight is 1,647.02 Daltons, and the isoelectric point is 11.05; and the complete sequence of the rana nigromaculata antimicrobial peptide is phenylalanine-isoleucine-proline-leucine-valine-serine-glycine-leucine-phenylalanine-serine-arginine-leucine-leucine-glycine-lysine. The coded gene of the rana nigromaculata antimicrobial peptide consists of 316 nucleotides, wherein the mature coded part of the coded gene contains 142nd-186th nucleotides. The artificially synthesized rana nigromaculata antimicrobial peptide has a strong antibacterial effect, has the advantages of high safety, simple sequence and convenience in synthesis, and can be used as a novel anti-infective agent for application.

The invention provides an amphibian boat and a clutch accelerating device used by the amphibian boat in order to overcome the defects that a recreating and sporting article in the prior art is single in function, some recreating and sporting articles can only move on a water surface, some recreating and sporting articles can only walk on land, and operation is inconveniently performed. The clutch accelerating device comprises a clutch frame, an upper fan-shaped wheel, a lower fan-shaped wheel, an upper driving wheel and a lower driving wheel, wherein the clutch frame is positioned between the upper fan-shaped wheel and the lower fan-shaped wheel; the clutch frame, the upper fan-shaped wheel and the lower fan-shaped wheel are coaxially arranged on a main shaft I; the clutch frame is fixedly connected with the main shaft I; the upper fan-shaped wheel and the lower fan-shaped wheel are rotationally connected with the main shaft I respectively; the upper fan-shaped wheel is connected with the upper driving wheel in a meshing and driving way; the lower fan-shaped wheel is connected with the lower driving wheel in a meshing and driving way; the lower driving wheel and a gear I are coaxially and fixedly arranged on a swing rod shaft; the upper driving wheel and a gear II are coaxially and fixedly arranged on a driving shaft I; the gear I and the gear II are connected in a meshing and driving way. According to the clutch accelerating device provided by the invention, when a rocker rod shakes for one time, the swing rod shaft swings for two times, so that the speed is high, and labor is saved.

The invention provides an amphibian space changeable multifunction architecture capable of floating on water, being arranged on land and changing space of a building according to requirements of people to achieve functional change. The amphibian space changeable multifunction architecture comprises a relative fixed building, and is characterized in that a building of which the space is changeable is arranged in the building to realize changing the space of the building through reciprocating sliding of a track or a rolling wheel set. When combined with a buoying device base on water, the architecture can be used as a water architecture; when a building construction part is detached with the buoying device base, the building construction part can also be arranged on the land and the buoying device base is still arranged in the water; and partial space of the fixed building construction can be changed and displaced in three-dimensional space under the conditions of the water and the land so as to make the space of the positioned environment generate novel combined forms. The amphibian space changeable multifunction architecture can greatly relieve the strain situation that construction-using land for towns is increased day by day.