46 results about "Arterial cannula" patented technology

A catheter system is provided for accessing the coronary ostia transluminally from a peripheral arterial access site, such as the femoral artery, and for inducing cardioplegic arrest by direct infusion of cardioplegic solution into the coronary arteries. In a first embodiment, the catheter system is in the form of a single perfusion catheter with multiple distal branches for engaging the coronary ostia. In a second embodiment, multiple perfusion catheters are delivered to the coronary ostia through a single arterial cannula. In a third embodiment, multiple perfusion catheters are delivered to the coronary ostia through a single guiding catheter. In a fourth embodiment, multiple catheters are delivered to the coronary ostia through a single guiding catheter which has distal exit ports that are arranged to direct the perfusion catheters into the coronary ostia. In each embodiment, the catheters are equipped with an occlusion means at the distal end of the catheter for closing the coronary ostia and isolating the coronary arteries from the systemic blood flow. The occlusion means can take the form of an inflatable occlusion balloon cuff, a tapered occlusion device or an O-ring encircling the distal end of the catheter. An optional ventricular venting catheter can be included in the system for venting blood and fluids from the left ventricle of the heart. The catheter system is combined with a femoral-to-femoral cardiopulmonary bypass system to provide a system for cardioplegic arrest and total cardiopulmonary support during minimally invasive cardiac surgical procedures.

A switch valve for use in an extracorporeal blood flow circuit comprises a valve housing having a chamber, four openings communicating with the chamber, and a valve member located in the valve chamber. A first opening is to be connected to a patient via an arterial cannula, a second opening is to be connected to a patient via an venous cannula, a third opening is to be connected to a first inlet / oulet of a blood treatment device, and a fourth opening is to be connected to a second inlet / outlet of a blood treatment device. The valve member is movable within the valve housing to fluidly connect the first opening to either the third or the fourth opening and to fluidly connect the second opening to either the third or the fourth opening. The width of the valve member is smaller than a peripheral dimension of the openings.

A switch valve for use in an extracorporeal blood flow circuit comprises a valve housing having a chamber, four openings communicating with the chamber, and a valve member located in the valve chamber. A first opening is to be connected to a patient via an arterial cannula, a second opening is to be connected to a patient via an venous cannula, a third opening is to be connected to a first inlet / oulet of a blood treatment device, and a fourth opening is to be connected to a second inlet / outlet of a blood treatment device. The valve member is movable within the valve housing to fluidly connect the first opening to either the third or the fourth opening and to fluidly connect the second opening to either the third or the fourth opening. The width of the valve member is smaller than a peripheral dimension of the openings.

A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

The present invention relates to a cannula for femoral arterial bidirectional (a heart direction and a distal lower extremity direction) perfusion. The cannula, which has a cannula tube to be inserted into a blood vessel of the femoral artery, includes a perfusion guide channel formed as a concave part from a predetermined portion of an inner circumferential surface at an end of the cannula tube to the opposite end thereof in a length direction and further includes a through-hole provided at a boundary portion between the perfusion guide channel and the cannula tube in an end direction of the cannula tube, or includes a through-hole provided in a predetermined portion of to an inner circumferential surface of an end of the cannula tube and a guide cover provided at an upper portion of the through-hole to cover the upper portion of the through-hole and guide perfusion. During surgery, perfusion proceeds towards the distal limb and thus blood may be stably supplied, and thus ischemia prevalence of the distal limb may be significantly reduced. Accordingly, the cannula can replace conventional techniques used for distal limb perfusion and may stably perform femoral arterial cannulation without technical difficulties such as complications or breakage of blood vessels.

A system and method is disclosed for measuring cardiac output. A closed fluid circuit is created between a patient's arterial cannula and venous cannula. A pump regulates flow through the closed fluid circuit. The closed fluid circuit includes at least one port for injection of an indicator. At least one sensor is attached to the closed fluid circuit for taking readings of a blood parameter after the indicator has flowed through the patients system at least once.

A method for determining the hematocrit and / or blood volume during an extracorporeal blood treatment with an extracorporeal blood circuit, in which blood is taken with a blood pump via an arterial cannula and an arterial flexible-tube line and blood is fed back via a venous flexible-tube line and a venous cannula. Pressure is measured in the extracorporeal blood circuit and a change in the hematocrit is determined from a change in the pressure. The respective relationship between hematocrit HKT or blood volume RBV and pressure P in the extracorporeal circuit is stored for various cannula diameters and various blood-flow values. The respective relationship for a given cannula diameter and blood flow is selected. The hematocrit and / or blood volume is determined taking account of the selected relationship.

An apparatus for performing myocardial revascularization in a beating heart and left ventricular assistance condition comprises an arterial cannula, of a per se known type, arranged in the descending aorta, a novel arterial draining cannula, of a two cannula stage type, so arranged that the draining occurs from the left auricle and left ventricle, and a centrifugal pump allowing blood flow from the left ventricle to the aorta. The apparatus allow the patients to be operated on with the safety of a conventional extra-corporeal circulation and with a risk and cost reduction due to the off-pump technique.

A modular blood filter device and delivery system, comprising an arterial cannula with a modular filter device. The arterial cannula includes a distal end adapted to enter an artery, and a side port for receiving a modular filter cartridge. The modular filter cartridge includes a tubular cartridge, and a shaft having a handle on one end and an expandable filter device on the other end. The expandable filter device includes filter mesh and an expansion frame capable of assuming enlarged and contracted conditions. The shaft is inserted into the cartridge, thereby containing the expandable filter device therein. The cartridge may then be removably received by the side port on the cannula. The cannula may be introduced into a blood vessel, and the expandable filter device may be deployed through the cannula into the vessel. The expansion frame may be expanded to the enlarged condition to capture embolic material in the mesh, may be collapsed to the contracted condition, and may be removed from the vessel. The modular filter cartridge may be removed from the cannula, and a new modular filter cartridge may then be received therein.

The invention relates to an amphibian isolated heart perfusion device. The device comprises an arterial cannula, a venous cannula, a drip recording electrode and an electrocardio lead electrode, wherein the arterial cannula is formed by combining an arterial cannula trunk, an aorta inserting end and a liquid discharging pipe through a three-way valve; the venous cannula is formed by combining a liquid storage tank, a postcaval vein inserting end and a liquid adding pipe through a three-way valve, and parts of the arterial cannula and the venous cannula are inserted and combined into one. The drip recording electrode comprises a drip recording electrode head, a drip recording electrode rod and a signal input end; the electrocardio lead electrode comprises an electrocardio lead electrode head, an electrocardio lead electrode rod, a signal input end, a heart outer wall liquid adding pipe and a three-way valve. The multifunctional amphibian isolated heart perfusion device is suitable for one person to operate, facilitates perfusion liquid replacement, and is suitable for synchronously and dynamically detecting dynamical changes of the cardiac output, myocardial contraction tension, electrocardiogram and various cardiac function indexes.

The venous reservoir is omitted from an extracorporeal blood circuit system by substituting a blood reservoir in parallel with the arterial pump. The reservoir has an inlet connected to the outlet of the pump and an outlet connected to the inlet of the pump. At least three blood flow paths can be configured. A main path has the inlet and outlet of the reservoir blocked while pumped blood flows through the venous cannula, the oxygenator, and the arterial cannula. An accumulator path has the inlet to the oxygenator and the outlet of the reservoir blocked while blood flows through the venous cannula and the inlet to the reservoir. A discharge path has the inlet of the reservoir blocked while the outlet is open whereby blood from the reservoir flows into the oxygenator. In a fourth configuration, the ECC fluid can be recovered in the reservoir and hemoconcentrated for autologous transfusion.

The invention provides an intelligent ECMO treatment device based on a rolling type blood pump and a control method of a system.The intelligent ECMO treatment device comprises a vein cannula, the rolling type blood pump, a membrane lung and an arterial cannula, the vein cannula is connected to an inlet of the rolling type blood pump through a first connecting pipe, and the rolling type blood pump is connected to an outlet of the artery cannula through a second connecting pipe; a venous pressure sensor is arranged on the first connecting pipe; an outlet of the rolling type blood pump is connected to an inlet of the membrane lung through an arteriovenous bridge tube, an artery overpressure sensor is arranged on the arteriovenous bridge tube, the membrane lung is further connected with an air and oxygen mixer and a temperature changing device, an outlet of the membrane lung is connected to the arterial cannula through a second connecting tube, and the arterial cannula is connected with the air and oxygen mixer through a second connecting tube. The venous pressure sensor and the artery overpressure sensor are respectively connected with the rolling type blood pump through the central processing unit. According to the invention, the perfusion pressure can be intelligently and accurately controlled, and finally constant-flow perfusion is achieved.

The invention discloses a portable organ donation donor mechanical perfusion system. The portable organ donation donor mechanical perfusion system comprises a blood circulation oxygenation closure device and a control device electrically connected with the blood circulation oxygenation closure device; the blood circulation oxygenation closure device comprises an oxygenator, a centrifugal pump, a blood exchanger, an arterial cannula, and a venous cannula; the blood exchanger is internally provided with a piston capable of moving vertically, the upper part of the piston is a first storage end for storing donor blood, the lower part of the piston is a second storage end for storing perfusion liquid, a blood input end and the output end of the centrifugal pump are communicated with the first storage end through a first three-way valve, and the blood input end and the output end of the centrifugal pump are communicated with the second storage end through a second three-way valve, so that low-temperature perfusion can be completed without cannulation in the abdominal aorta after laparotomy. Moreover, since a balloon is arranged at the tip end of the arterial cannula, only the balloon isneeded to be inflated or injected with water when only an abdominal organ is perfused, and convenience is realized.

The present invention relates to a liquid light conduction device for intervention. The device comprises a conduit with an internal portion which is a cavity, one end of the conduit is provided with a tail sheath, and the other end of the conduit is provided with a liquid-laser coupler capable of injection of liquid medium and conduction of laser; the tail sheath is provided with an outlet; a metal reflection layer is arranged at the inner wall of the conduit, the liquid medium can be transmitted in the conduit, and the laser can be transmitted in the liquid coated with the metal reflection layer and can be transmitted out through the tail sheath. The liquid light conduction device for intervention can introduce laser and liquid medicine into the artery to directly reach diseased regions through adoption of the Seldinger arterial cannula technology, the laser is conducted through the liquid medicine conduit coated with the metal reflection layer, and the medicine and the laser can reach the diseased regions through blood vessels in a tumour for treatment to allow a photosensitizer and the laser to be directly effected on deep tumors so as to enhance the treatment effect and relieve toxic and side effects.

A method comprising recirculating a patient's blood as a fluid through an extracorporeal circuit having a venous cannula line for fluid flow from the patient to an oxygenator and an arterial cannula line for fluid flow from the oxygenator to the patient; and adjusting the volume of fluid flow from the venous cannula line to the arterial cannula line by selectively redirecting fluid flow between the venous cannula line and the arterial cannula line into or out of a closed accumulator blood bag of substantially transparent, bio-compatible material, having a selectively open and closable accumulator inlet line from the venous cannula, and a selectively open and closable accumulator outlet line to the oxygenator.

The invention discloses a life rescue box for first aid of sudden cardiac arrest and acute respiratory failure patients, which is characterized in that main components such as a blood pump, a membrane oxygenator and the like required by extracorporeal life support are assembled in the life rescue box, and the blood pump and the membrane oxygenator are fastened on an upright post in a magnetic force manner; the blood pump is provided with a first interface and a second interface, wherein the first interface is connected with a venous cannula, and the second interface is connected with the membrane oxygenator through a connecting pipe; and the membrane oxygenator is provided with a first interface and a second interface, wherein the first interface is connected with an arterial cannula, and the second interface is connected with the blood pump through a connecting pipe to form a blood circulation loop with the blood vessel of human bodies for alternatively completing the cardio-pulmonary function of the sudden cardiac arrest and acute respiratory failure patients. Due to small size, the life rescue box can be carried with an ambulance and an on-vehicle stretcher, is convenient to move and simple to operate, can reach the primary disease outbreak scene with medical personnel in the shortest time during first aid and can be generally used for the first aid of the sudden cardiac arrest and acute respiratory failure patients.

Adaptors, cannulas, caps, tube couplers, and systems thereof provide endovascular access through an established ECLS system. Adaptors having curved or angled shafts navigate right angle side ports of standard bypass cannulas and permit hemostatic introduction and direction of an intervention device to the axial flow path of the cannula lumen and bypass system. A modified cannula having an angled side port is also provided for use as an arterial cannula. A cap having an occluding surface may be inserted into the angled side port to prevent blood from stagnating in the angled side port. A tube coupler is also provided having an access port, such as an angled access port, and may be spliced into an established bypass system for vascular access point. Multiple couplers can be used to provide multiple access points. The adaptors and occlusive cap are interchangeable with each other and with secondary circuits.

Adaptors, cannulas, caps, tube couplers, and systems thereof provide endovascular access through an established ECLS system. Adaptors having curved or angled shafts navigate right angle side ports of standard bypass cannulas and permit hemostatic introduction and direction of an intervention device to the axial flow path of the cannula lumen and bypass system. A modified cannula having an angled side port is also provided for use as an arterial cannula. A cap having an occluding surface may be inserted into the angled side port to prevent blood from stagnating in the angled side port. A tube coupler is also provided having an access port, such as an angled access port, and may be spliced into an established bypass system for vascular access point. Multiple couplers can be used to provide multiple access points. The adaptors and occlusive cap are interchangeable with each other and with secondary circuits.

The invention provides an arterial infusion cannula for blood flow distribution and adjustment and an application thereof. The arterial infusion cannula comprises a cannula body at the blood supply end, and is characterized in that a proximal end tube, a distal end tube and a T-type or Y-type extracorporeal circulation infusion tube formed on an overall structure are included, the proximal end tube and the distal end tube are communicated with the cannula body and have flow distributing and pressure sharing functions, and an included angle is formed between the proximal end tube of the Y-type infusion tube and the cannula body of the blood supply end so that flow of injected blood can be distributed or adjusted. The arterial infusion cannula is used for whole-body artery infusion and deep hypothermic circulatory arrest selective cerebral perfusion when a right common carotid artery carries out extracorporeal circulation, and meanwhile can prevent ischemia of the right upper limb; the arterial infusion cannula can be used for femoral arteries to guarantee blood supply of the proximal end and the distal end and can prevent ischemia of lower limbs. Obviously, the arterial infusion cannula is convenient to operate and high in universality, defects of an existing arterial cannula are overcome, ischemia time of the brain or limbs of a patient is reduced, the success rate of aortic arch surgeries is improved and accordingly the arterial infusion cannula is widely used.

A method for determining the hematocrit and / or blood volume during an extracorporeal blood treatment with an extracorporeal blood circuit, in which blood is taken with a blood pump via an arterial cannula and an arterial flexible-tube line and blood is fed back via a venous flexible-tube line and a venous cannula. Pressure is measured in the extracorporeal blood circuit and a change in the hematocrit is determined from a change in the pressure. The respective relationship between hematocrit HKT or blood volume RBV and pressure P in the extracorporeal circuit is stored for various cannula diameters and various blood-flow values. The respective relationship for a given cannula diameter and blood flow is selected. The hematocrit and / or blood volume is determined taking account of the selected relationship.

The invention relates to a method and to a device for recognition of paravasal bleeding upon a supplying of blood to a vascular access via a line and / or upon the removal of blood from a vascular access via a line, particularly paravasal bleeding during extra-corporeal blood treatment, such as for hemodialysis, hemofiltration or hemodiafiltration. The invention furthermore relates to a device for extra-corporeal blood treatment, particularly for hemodialysis, hemofiltration or hemodiafiltration, comprising a device for recognition of paravasal bleeding. The method according to the invention and the device according to the invention are based on the change of arterial pressure in the arterial branch (5) or the venous pressure in the venous branch (7) of the extra-corporeal circuit (I) being registered during the extra-corporeal blood treatment. If paravasal bleeding occurs during the blood treatment, it is shown that the positive dynamic pressure on the line leading to the vascular access rises on the venous cannula during the extra-corporeal blood treatment, or the suction pressure on the line leaving the vascular access, such as the arterial cannula during extra-corporeal blood treatment, rises; that is, the suction pressure becomes more negative. The pressure rise begins moderately at first and then becomes increasingly greater. Decisive for the method according to the invention and the device according to the invention, therefore, is that pressure changes that come from a pressure level exhibiting a large difference from the reference value find stronger consideration than those that come from a pressure level that exhibits only a minor difference from the reference value.

The invention relates to the technical field of a clinical scientific research, and discloses preparing experimental materials: a 18gage needle, a 5F arterial cannula, a 4F angiography catheter, a 0.25mm angiography micro-guidewire, a digital subtraction angiography (DSA) system, a MRI System, a nuclear magnetic resonance compatible respirator, a nuclear magnetic resonance compatible physiologicalsignal detection system. The development method is characterized in that a stable cerebral ischemia-reperfusion animal model of cynomolgus monkey is accurately prepared by intravascular coil embolization, the infarct size of the experimental animal is moderate and no hemorrhagic transformation in the infarct area is generated after reperfusion, the animal can survive for a long time, has the corresponding symptoms of neurological deficit, and the stability of the model is proved through long-term imaging and behavioral evaluation. The method can accurately control the location and extent of stroke, and the experimental animals are able to maintain stable clinical symptoms, so the model is suitable for the assessment of the safety and efficacy of new therapy and new drugs for stroke.

The present invention relates to a cannula for femoral arterial bidirectional (a heart direction and a distal lower extremity direction) perfusion. The cannula, which has a cannula tube to be inserted into a blood vessel of the femoral artery, includes a perfusion guide channel formed as a concave part from a predetermined portion of an inner circumferential surface at an end of the cannula tube to the opposite end thereof in a length direction and further includes a through-hole provided at a boundary portion between the perfusion guide channel and the cannula tube in an end direction of the cannula tube, or includes a through-hole provided in a predetermined portion of an inner circumferential surface of an end of the cannula tube and a guide cover provided at an upper portion of the through-hole to cover the upper portion of the through-hole and guide perfusion. During surgery, perfusion proceeds towards the distal limb and thus blood may be stably supplied, and thus ischemia prevalence of the distal limb may be significantly reduced. Accordingly, the cannula can replace conventional techniques used for distal limb perfusion and may stably perform femoral arterial cannulation without technical difficulties such as complications or breakage of blood vessels.

An assembly for an extracorporeal life support system with a suction line that features a venous cannula and a pressure line that features an arterial cannula furthermore includes a pump that is arranged between the suction line and the pressure line. This assembly has a discharge line with a discharge cannula, wherein the discharge cannula is longer than the arterial cannula, and wherein the discharge line is connected to the suction line or the pressure line.

Provided are methods for creating a pressurized cadaver model used for surgical procedure training. In the method the internal jugular veins, common carotid arteries, brachial arteries, superficial femoral arteries and femoral veins thereof of a cadaver are exposed. One internal jugular vein is ligated and a drainage tube is disposed in the other internal jugular vein. An arterial catheter is inserted into one brachial artery and connected to a pressure transducer and an arterial cannula is placed in a carotid artery and connected to a fusion pump. Fluid is injected into the artery through the cannulated carotid artery. A representative example of the surgical procedure includes resuscitative endovascular balloon occlusion of the aorta.

The invention relates to a device for use in an arrangement for monitoring a patient access, in particular a vascular access in extracorporeal blood treatment, which device is used to establish a connection between the arterial and venous tubes (6, 7) or the arterial and venous puncture needles (5, 8; 37, 38), wherein the needles (37, 38) are oriented substantially parallel to each other. If the venous needle (38) slips out of the vascular access, the arterial cannula (37) is forcibly withdrawn. This incident is reliably detected by the known protection systems which, in order to monitor the correct fit of the arterial needle, monitor the pressure in the arterial tube (6) and / or an air intake. In addition, the invention relates to an extracorporeal blood treatment device and to a method for monitoring a patient access, wherein the venous and arterial tubes or the puncture needles are connected to each other.

Adaptors, cannulas, caps, tube couplers, and systems thereof provide endovascular access through an established ECLS system. Adaptors having curved or angled shafts navigate right angle side ports of standard bypass cannulas and permit hemostatic introduction and direction of an intervention device to the axial flow path of the cannula lumen and bypass system. A modified cannula having an angled side port is also provided for use as an arterial cannula. A cap having an occluding surface may be inserted into the angled side port to prevent blood from stagnating in the angled side port. A tube coupler is also provided having an access port, such as an angled access port, and may be spliced into an established bypass system for vascular access point. Multiple couplers can be used to provide multiple access points. The adaptors and occlusive cap are interchangeable with each other and with secondary circuits.

The invention relates to an experimental device for changing toad heart afterload, and mainly solves the technical difficulty that the existing experimental device does not conform to the physiological status and clinical practices of a body. The experimental device comprises an arterial cannula, a main output pipe, a main pipe, a main pipe sleeve, side pipes, side pipe sleeves, output pipes and plugs. In use, the two ends of the main output pipe are respectively connected with the M ends of the arterial cannula and the main pipe, and the output pipes of different sizes can be optionally connected with or dismounted from the corresponding side pipes. The output quantity of a certain output pipe is measured, when required, by firstly connecting the output pipes and the corresponding side pipes and simultaneously closing all of the other side pipes with the corresponding plugs. The experimental device provided by the invention uses the output pipes of different sizes to manifest the degree of arteriostenosis and reflect the change in peripheral blood resistance and the change in heart afterload. The experimental device has the characteristics of reasonable and compact structure and accurate measurement, and is simple for operation.

The invention relates to the technical field of medical auxiliary equipment, and provides an intervention auxiliary device which is used for percutaneous coronary intervention operation assisted by extracorporeal membrane oxygenation equipment. The extracorporeal membrane oxygenation equipment comprises a connecting cannula and an arterial cannula; the intervention auxiliary device comprises a pipeline connector and a first side branch installed on the pipeline connector; the pipeline connector is provided with a connecting cannula head used for being connected with the connecting cannula in an inserted mode and an arterial cannula head used for being connected with the arterial cannula in an inserted mode; the pipeline connector is installed on the connecting cannula and the arterial cannula of the extracorporeal membrane oxygenation equipment to replace a conventional operation catheter sheath for percutaneous coronary intervention operation, so that the problem that sheath placement operation needs to be additionally carried out on the peripheral artery of an arm in the percutaneous coronary intervention operation assisted by extracorporeal membrane oxygenation at present is effectively solved; and therefore, the surgical risk is reduced, complications of peripheral blood vessels are avoided, and the economic burden and puncture burden of the patient are reduced.