A sinusoidal tension cell loading device relates to a cell mechanical loading device in medical experiment instruments. The invention mainly includes a frame, a gear reduction speed regulating motor, a digital display speed governor, a crank slider mechanism and a stretching movement mechanism. The slider crank mechanism is mainly composed of an adjusting screw rod, a crank arm slider, a crank and a pull rod; the stretching motion mechanism is mainly composed of a sliding bracket, a fixed bracket, a guide rod, a front guide rod block and a rear guide rod block. Since the present invention has the characteristics of simple structure, easy operation, convenient maintenance, low cost, stable operation, high cost performance, uniform stress on cells, adjustable stretching amplitude and frequency, etc., the stretching distance can be easily adjusted within the range of 0-25mm, It can meet the mechanical stimulus response research of tensile loading of various adherent growth cells, so the present invention can be widely used as a cell mechanical loading device in medical experimental instruments, and is especially suitable for wide application in research institutions lacking funds and professional operators .