The invention discloses a ganoderma health-care rice wine, which comprises the following raw materials in parts by weight: 10-20 ganoderma lucidum, 5-8 gastrodia elata, 1-3 chuanqiong, 1-3 cassia twig, 2-4 medlar and 2-3 radix radix , Lily 3~5, raspberry 2~4, licorice 2~3, rice wine 80~100. The present invention uses Ganoderma lucidum and rice wine as main raw materials, and uses Gastrodia elata, Chuanqiong, Guizhi, Lycium barbarum, etc. as compatibility to make Ganoderma lucidum health-care rice wine with various medicinal and health-care functions. Breathing, prolonging life, calming liver yang, dispelling wind and collaterals, activating blood and promoting qi, warming meridians, moistening lung and clearing heart, nourishing kidney and spleen, etc. It can be used for dizziness, insomnia, palpitations, shortness of breath, neurasthenia, fatigue cough, headache, dizziness , rheumatic arthralgia, irregular menstruation, wind-cold exterior syndrome, bruises, swelling and pain, asthenia and essence deficiency, consumptive tuberculosis and cough, weakness of the spleen and stomach, etc.