The invention provides a folding mobile box house, which comprises a top plate, a bottom plate, two end plates and a plurality of roller blind walls, wherein the top plate and the bottom plate are arranged in a longitudinal-symmetry manner; two short edges of the two end plates are symmetrically arranged. The folding mobile box house is characterized in that the middles of two long-edge sides of the top plate and the bottom plate are symmetrically provided with horizontal drive rods; upper and lower edges of the two long-edge sides of the top plate and the bottom plate are symmetrically provided with a plurality of groups of side upright columns; the side upright columns of each group are connected through connecting pieces and the drive rods; the connecting pieces and the side upright columns are driven to move through rotating the drive rods, so as to realize the folding of the box house. The box house provided by the invention can be repeatedly utilized, can be used for multiple times with one-time investment, is short in setting-up time, is used for saving a space and is convenient to transport; further, the box house is formed by assembling modular components, and further, canbe subjected to modular flow-line production and further, in special and severe environments, the box house can be folded and unfolded without needing the help of other large machines and extra powerto carry out cooperation.