35results about How to "Reduce the effect of activity" patented technology

The invention relates to a continuous production device for synthesizing 2,2'-dipyridyl and a production method. The production device comprises a reaction system, wherein the reaction system comprises a fixed bed reactor for synthesizing 2,2'-dipyridyl from pyridine through direct coupling; a pyridine conveying system and a gas carrying system are connected with the inlet of the fixed bed reactor; a product condensation separation system and a circulation system which is for feeding back unreacted pyridine into the pyridine conveying system are sequentially connected with the outlet of the fixed bed reactor; the product condensation separation system comprises a condenser A and a gas-liquid separator which are arranged in sequence; a membrane separator for separating product hydrogen is mounted at a gas phase outlet of the gas-liquid separator; a recycling system for recycling the product, namely the 2,2'-dipyridyl, is connected with a liquid-phase outlet of the gas-liquid separator;the outlet of the recycling system is connected with the circulation system. By adopting the continuous production device, the conversion per pass of the 2,2'-dipyridyl is greatly increased, high-efficiency production process can be achieved, and a technique is provided for continuous industrial direct-coupling production of 2,2'-dipyridyl.

The invention discloses a label-free cell detection device and method based on light sheet illumination. The method includes the steps that a light sheet generation unit is used for shaping a laser beam into a uniform illumination light sheet with the micron-order thickness through a cylinder lens; the light sheet excites particles or a cell suspension placed in a sample micro-cavity chamber controlled by a precise displacement table to move; a form microscopic image and a two-dimensional light scattering pattern of a single particle or cell are recorded by a detector under the focusing mode and the defocusing mode through an objective lens; and a result is input into an imaging analysis system for image processing and recognizing and classifying. By means of the light sheet illumination method, a stimulation area can be effectively limited, background interference in light scattering imaging is inhibited, and effective stimulation of the single particle or cell and particle size discrimination of the sub-micron resolution ratio level are realized; and a light sheet illumination stimulation two-dimensional light scattering technology can avoid complex dyeing operation and a fluorescence signal detection process, and label-free detection and classification are carried out on aging cells. The label-free cell detection device and method based on light sheet illumination are high in applicability and capable of being popularized.

The invention provides a storage reagent for biotinylation inorganic pyrophosphatase. The storage reagent is prepared from 60-90 mM of Tris-HCL with the pH being 8.5, 25-75 mM of calcium chloride, 25-75 mM of magnesium chloride, 20-35% ethanediol and 2-4 mM of DTT. The solvent is deionized water. The storage reagent can protect the activity of the biotinylation inorganic pyrophosphatase, the storage time of the biotinylation inorganic pyrophosphatase can be prolonged, the influence caused by repeated freezing thawing on the activity of the biotinylation inorganic pyrophosphatase is lowered, and the phenomenon that biotin labels on the biotinylation inorganic pyrophosphatase fall down can be effectively reduced.

The present disclosure provides a droplet ejection device and related methods. The droplet ejection device comprises: a piezoelectric chip, an interdigital transducer arranged on the upper surface of the piezoelectric chip; the ratio of the thickness of the piezoelectric chip to the period of the interdigital transducer is 1 to 3 ; The interdigital transducer excites surface acoustic waves and bulk acoustic waves in the piezoelectric chip under the drive of radio frequency signals, and the surface acoustic waves and the bulk acoustic waves are reflected on the upper and lower surfaces of the piezoelectric chip to generate recombination Acoustic waves, to drive the liquid to be driven on the liquid attachment area to stretch along the direction perpendicular to the surface of the piezoelectric chip to form a liquid column, so that the liquid column will have a droplet pinch-off effect at the end, and a single droplet will be ejected; the liquid The attachment area is located on the upper surface and / or the lower surface of the piezoelectric chip corresponding to the area covered by the propagation of the surface acoustic wave generated by the interdigital transducer along the surface of the piezoelectric chip. It solves the problems of complicated device structure, high cost, low efficiency, and inconvenient realization of on-demand injection.

The invention relates to a loaded non-metallocene catalyst and its preparation method. The loaded non-metallocene catalyst has the characteristics of simple and feasible preparation process, controllable non-metallocene component content, and substantial copolymerization effect, etc. The invention also relates to application of the loaded non-metallocene catalyst in olefin homopolymerization / copolymerization. Compared with the prior art, during application, the loaded non-metallocene catalyst has high olefin polymerization catalytic activity, small particle size and uniform distribution, and the obtained polymer has a high bulk density.

The invention belongs to the technical field of medicine, and in particular relates to the use of black sesame pigment and a preparation method thereof. Tests have confirmed that the black sesame pigment prepared by the present invention has significant cellular antioxidant activity and antitumor activity, and can significantly inhibit the growth of cancer cells (HGC, AGS, SGC-7901, A549, HEPG-2 and MCF-7) , the mortality rate of cancer cells is as high as 95-99%, and it can be used in the preparation of anti-tumor drugs or health products for cancer patients, special medical food.

The invention relates to a loaded non-metallocene catalyst and its preparation method. The loaded non-metallocene catalyst has the characteristics of simple and feasible preparation process, controllable non-metallocene component content, and substantial copolymerization effect, etc. The invention also relates to application of the loaded non-metallocene catalyst in olefin homopolymerization / copolymerization. Compared with the prior art, during application, the loaded non-metallocene catalyst has high olefin polymerization catalytic activity, small particle size and uniform distribution, and the obtained polymer has a high bulk density.

The invention discloses an enhanced isoluminol derivative with high luminous intensity and a preparation method thereof, and aims to enhance the luminous intensity of an existing luminol-peroxide system, increase the test sensitivity and detection limit, lower the quantity of antibodies or antigens labelled by a luminescent label, and lower the influence of excessive labelling on the antibody or antigen activity. The invention further discloses a chemiluminescent base solution containing the isoluminol derivative, or a chemiluminescent kit containing the antigens or the antibodies labeled by the isoluminol derivative, and a chemiluminescent immunoassay system, and aims to solve the technical problems of low sensitivity and low detection limit when the existing luminol-peroxide system is used for testing. The invention further provides application of the isoluminol derivate to chemiluminescent immune quantitative analyses.

The invention relates to a loaded non-metallocene catalyst and its preparation method. The loaded non-metallocene catalyst has the characteristics of simple and feasible preparation process, controllable non-metallocene component content, and substantial copolymerization effect, etc. The invention also relates to application of the loaded non-metallocene catalyst in olefin homopolymerization / copolymerization. Compared with the prior art, during application, the loaded non-metallocene catalyst has high olefin polymerization catalytic activity, small particle size and uniform distribution, and the obtained polymer has a high bulk density.

The invention relates to a rapid stop method in a methanol-to-olefin reaction-regeneration system, mainly solves the problems of long stop time and non-uniform catalyst coke burning and activity loss during the stop process in the prior art. The method comprises the following steps: a. gradually cutting the materials containing methanol out of a reactor and cutting the vapor in the reacting system; b. continuously cycling the catalyst in a reaction-regeneration system; c. spraying burning oil at the dense phase section of the regenerator when the temperature of the regenerator is lower than 600 DEG C; d. stopping spraying the burning oil to the regenerator after the coke content of the catalyst is less than 0.5% by weight; e. closing a slide valve on a regenerator inclined tube when the temperature is down to 500-550 DEG C; f. conveying the catalyst in the reactor to the regenerator while unloading the catalyst in the regenerator; g. reducing the pressure of the reaction-regenerationsystem after finishing unloading. The technique scheme of the invention well solves the above problem and is suitable to the industrial production of light olefins.