540results about How to "Reduce shear stress" patented technology

Arthroplasty devices having improved bone in growth to provide a more secure connection within the body. Different embodiments disclosed include devices having threaded intramedullary components, devices configured to receive bone growth promoting substances, devices with resorbable components, and devices configured to reduce shear stress.

Arthroplasty devices having improved bone in growth to provide a more secure connection within the body. Different embodiments disclosed include devices having threaded intramedullary components, devices configured to receive bone growth promoting substances, devices with resorbable components, and devices configured to reduce shear stress.

The present invention provides cryotherapy treatment of dissections in a blood vessel of a patient. The present invention further provides cryotherapy treatment of side branch occlusion in a bifurcated blood vessel. One method for treating potential or existing dissections in a blood vessel comprises cooling the blood vessel to a temperature and for a time sufficient to remodel the blood vessel such that dissections of the blood vessel are reduced. Another method for treating side branch occlusion in a bifurcated blood vessel, the bifurcated blood vessel having a side branch and a main branch, the main branch having plaque disposed thereon, comprises cooling an inner surface of the main branch to a temperature and for a time sufficient to inhibit plaque shift from the main branch into the side branch.

A method to produce on a commercial scale, high aspect ratio cellulose nanofilaments (CNF) from natural lignocellulosic fibers comprises a multi-pass high consistency refining (HCR) of chemical or mechanical fibers using combinations of refining intensity and specific energy. The CNF produced represents a mixture of fine filaments with widths in the submicron and lengths from tens of micrometers to few millimeters. The product has a population of free filaments and filaments bound to the fiber core from which they were produced. The proportion of free and bound filaments is governed in large part by total specific energy applied to the pulp in the refiner, and differs from other cellulose fibrillar materials by their higher aspect ratio and the preserved degree of polymerization (DP) of cellulose, and are excellent additives for the reinforcement of paper, tissue, paperboard and the like. They display exceptional strengthening power for never-dried paper webs.

Biomaterials with enhanced properties such as improved strength, flexibility, durability and reduced thickness are useful in the fabrication of biomedical devices, particularly those subjected to continuous or non-continuous loads where repeated flexibility and long-term durability are required. These enhanced properties can be attributed to elevated levels of elastin, altered collagen types, and other biochemical changes which contribute to these enhanced properties. Examples of devices which would be improved by use of such tissue include heart valves, including percutaneous heart valves, and vascular grafts, patches and the like. Such enhanced materials can be sourced from specific populations of animals, such as neonatal calves, or in range-fed adult cattle, or can be fabricated or created from cell populations exhibiting such properties. In one embodiment, glutaraldehyde-fixed neonatal pericardial tissue is used to create leaflets in a percutaneous heart valve, and may be used without chemical fixation, with or without processes to remove residual cellular membranes, and utilized as a scaffold material for tissue engineering.

The present invention provides cryotherapy treatment of dissections in a blood vessel of a patient. The present invention further provides cryotherapy treatment of side branch occlusion in a bifurcated blood vessel. One method for treating potential or existing dissections in a blood vessel comprises cooling the blood vessel to a temperature and for a time sufficient to remodel the blood vessel such that dissections of the blood vessel are reduced. Another method for treating side branch occlusion in a bifurcated blood vessel, the bifurcated blood vessel having a side branch and a main branch, the main branch having plaque disposed thereon, comprises cooling an inner surface of the main branch to a temperature and for a time sufficient to inhibit plaque shift from the main branch into the side branch.

High radiopacity is achieved in a polymeric marker by combining a polymeric resin, a powdered radiopaque agent having uniformly shaped particles of a specific particle size distribution, and a wetting agent. The method to produce the marker calls for the blending and pelletization of these materials followed by extrusion onto support beading. The resulting supported tubing is subsequently cut to length with the beading still in place. After ejection of the beading remnant the marker is slipped into place on the device to be marked and attached by melt bonding. Marking of a guide wire allows lesions to be measured while the marking of balloon catheters allow the balloon to be properly positioned relative to a lesion.

Method of manufacture of a composite wiring structure for use with at least one semiconductor device, the structure having a first conductive member upon which the semiconductor device can be mounted for electrical connection thereto. A dielectric member, made of ceramic or organo-ceramic composite material, is bonded to the first conductive member and contains embedded therein a conductive network and a thermal distribution network. A second conductive member may be incorporated with the composite wiring structure, with a capacitor electrically connected between the conductive network and the second conductive member. Bonding between the dielectric member and the conductive members may be in the form of a direct covalent bond formed at a temperature insufficient to adversely effect the structural integrity of the conductive network and the thermal distribution network.

Arthroplasty devices having improved bone in growth to provide a more secure connection within the body. Different embodiments disclosed include devices having threaded intramedullary components, devices configured to receive bone growth promoting substances, devices with resorbable components, and devices configured to reduce shear stress.

Arthroplasty devices having improved bone in growth to provide a more secure connection within the body. Different embodiments disclosed include devices having threaded intramedullary components, devices configured to receive bone growth promoting substances, devices with resorbable components, and devices configured to reduce shear stress.

A grafting reagent and related method of using the reagent to form a polymeric layer on a support surface, and particularly a porous support surface, in a manner that provides and / or preserves desired properties (such as porosity) of the surface. The reagent and method can be used to provide a thin, conformable, uniform, uncrosslinked coating having desired properties onto the surface of a preformed, and particularly a porous, polymeric substrate. The method includes the steps of a) providing a porous support surface, b) providing a nonpolymeric grafting reagent comprising a photoinitator group, c) providing one or more polymerizable monomers adapted to be contacted with the surface, in the presence of the grafting reagent, and to be polymerized upon activation of the photoinitiator; and d) applying the grafting reagent and monomer(s) to the surface in a manner, and under conditions, suitable to coat the surface with the grafting reagent and to cause the polymerization of monomers to the surface upon activation of the grafting reagent.

A bucket assembly is provided with a kit that includes a base plate for permanent connection to a lower part of the bucket, and sacrificial, impermanent replaceable wear edge segments for the forward lip and corner leading edges of an excavator or loader bucket. These segments form a set of “bolt on” cast wear members and wing wear segments. The base plate and wear plates are drilled and machined to accommodate the precision fitting bolting on of the replaceable lips and cast wing segments. The cast lip segments are of both left and right hand configurations and come in a variety of widths that, in combination, may tend to fit a large number of different commercially available bucket sizes. The lip top and bottom faces are shaped in a profile that may tend to result in relatively uniform wear and a reduction in friction when digging into various materials.

This invention provides compositions and methods providing, e.g., stable powder particles containing bioactive materials. The methods include, e.g., high pressure spraying of the bioactive materials in solution or suspension, with viscosity enhancing agents and / or surfactants. Compositions of the invention provide, e.g., high initial purity, high stability in storage, and reconstitution at high concentrations.

Arthroplasty devices having improved bone in growth to provide a more secure connection within the body. Different embodiments disclosed include devices having threaded intramedullary components, devices configured to receive bone growth promoting substances, devices with resorbable components, and devices configured to reduce shear stress.

Provided are a power device package coupled to a heat sink using a bolt and a semiconductor package mold for fabricating the same. The power device package includes: a substrate; at least one power device mounted on the substrate; a mold member sealing the substrate and the power device; and at least one bushing member fixed to the mold member to provide a through hole for a bolt member for coupling a heat sink to the mold member.

The invention relates to a nanometer zirconium oxide thermal barrier coating and a preparation method thereof. The nanometer zirconium oxide thermal barrier coating is characterized by comprising an adhesive layer and a ceramic layer, wherein NiCrAlY is prepared on the adhesive layer by adopting supersonic flame spraying and comprises the following components in percentage by weight: 20-30% of Cr, 4.0-10% of Al, 0.3-0.7% of Y, and the balance of Ni; a ZrO2 / Y2O3 layer is prepared as the ceramic layer by adopting plasma spraying, the ceramic layer is a nanometer zirconium oxide layer comprising5%-8% of partially stable yttrium oxide, and zirconium oxide powder is at a nanometer grade. The oxidation-resisting thermal barrier coating is prepared on a metal surface by combining the supersonic flame spraying with the plasma spraying, has better combining capacity with a base body and both thermal shock resistance and thermal insulation superior to those of a common ZrO2 / Y2O3 thermal barrier coating.

Provided are a nitride semiconductor light emitting element which does not suffer a damage on a light emitting region and has a high luminance without deterioration, even though the nitride semiconductor light emitting element is one in which electrodes are disposed opposite to each other and an isolation trench for chip separation and laser lift-off is formed by etching; and a manufacturing method thereof. An n-type nitride semiconductor layer 2 has a step, formed in a position beyond an active layer 3 when viewed from a p side. Up to the position of this step A, a protective insulating film 6 covers a part of the n-type nitride semiconductor layer 2, the active layer 3, a p-type nitride semiconductor layer 4, the side of a p electrode 5 and a part of the top side of the p electrode 5. The use of a structure having a chip side face covered with the protective insulating film 6 prevents the active layer or the like from being exposed to an etching gas for a long time when an isolation trench for chip separation or laser lift-off is formed by etching.

A motorcycle frame including a base portion and a removable portion that both bear operating loads of the motorcycle. The removable portion and base portion are fastened together at a joint comprising a first end cap having a protrusion, a second end cap having a recess, and a fastener having a fastener axis and extending through the first and second end caps. The protrusion and the recess are characterized by angled walls oriented at an acute angle with respect to the fastener axis. The angled wall engagement of the end caps ensures that substantially all shear loads in the joint are born by the end caps and not by the fastener. The motorcycle footpeg position can be changed by replacing the removable portion with a second removable portion having footpeg mounting structure at a different location than the removable portion.

The invention provides a melt-processable conductive fluorothermoplastic composition comprising three components. The first component is at least one melt-processable, thermoplastic fluoropolymer component having its interpolymerized units derived from (i) at least 50 wt % of TFE, and (ii) one or more ethylenically-unsaturated monomers represented by the formulas (a) CF2=CF-Rf, (b) CF2=CF-O-Rf', and (c) CH2=CR2, wherein Rf is a perfluoroalkyl of 1 to 8 carbon atoms, Rf' is Rf or a perfluoroalkoxy of 1 to 8 carbon atoms, and R is selected from H, F, Cl, or an aliphatic group having from 1 to 8 carbon atoms which may have F or Cl substituents. The thermoplastic fluoropolymer component is substantially free of interpolymerized units derived from VDF. The second component is from about 0.1 to about 10 weight percent of a hydrocarbon polymer, and the third component is from about 1 to about 20 weight percent of conductive filler. The invention also provides a method for making fluorothermoplastic compositions and shaped articles comprising a conductive fluorothermoplastic composition.

The invention is a pipe joint that is particularly suitable for joining pipes composed of materials having a low surface energy and excellent resistance to solvents. The major components are an extrudable adhesive; a first pipe having a socket with an inside diameter, where said socket has a mouth, a self-centering bottom, and a substantially cylindrical wall with an inlet, an outlet, and an inner annular channel; a second pipe having an insertion section with an end and an outer annular channel, said second pipe having an outside diameter that is less than the inside diameter of the socket, where the difference in diameters defines a gap and where the outer annular channel lines up with the inner annular channel therein forming an interlocking keyway; and a flanged annular ring, where said annular ring has an inside diameter that enables it to be slid over the second pipe and a thickness that is comparable to the gap, and where the flange has a width that is sufficient to cap the mouth of the socket. When fully formed, the adhesive has changed to a solid material that substantially fills the gap and the interlocking keyway, and serves as a mechanical key in the interlocking keyway. The adhesive is preferably an alkyl borane adhesive.

A pipe joint for joining pipes having a low surface energy and resistance to solvents. The components are an extrudable adhesive; a first pipe having a socket with an inside diameter, where the socket has a mouth, a self-centering bottom, and a cylindrical wall with an inlet, an outlet, and an inner annular channel; a second pipe having an insertion section with an end and an outer annular channel, where the second pipe has an outside diameter that is less than the inside diameter of the socket, the difference in diameters defining a gap and an interlocking keyway; and a flanged annular ring. The annular ring has an inside diameter that enables it to be slid over the second pipe and a thickness that is comparable to the gap. When the adhesive cures it forms a mechanical key. The adhesive is preferably an alkyl borane adhesive.

Arthroplasty devices having improved bone in growth to provide a more secure connection within the body. Different embodiments disclosed include devices having threaded intramedullary components, devices configured to receive bone growth promoting substances, devices with resorbable components, and devices configured to reduce shear stress.

The present invention is intended to provide a metal jacket for a cementless artificial joint stem, wherein shear force detrimental to the service life of an artificial joint can be markedly reduced and stress shielding phenomena can also be markedly relieved, due to the construction of the metal jacket which can be fixed to the bone and can enclose the surface of the stem so as to allow for the stem of artificial joint to slide vertically relative to the bone, and wherein osteolysis of a bone due to the infiltration of wear particles can be minimized by curbing the gap formation between the bone and the stem.To that end, there is provided according to the invention, a metal jacket for a cementless artificial joint stem, which jacket is so formed as to enclose at least a part of the cementless artificial joint stem 21, said stem with jacket being inserted longitudinally in the opening formed in the bone canal of a human body, and on the surface of which jacket surface-processed metal layer or metal wires 12 is formed so that the bone can make interlocking with the metal jacket as the bone gets on-growth onto the metal jacket.

A device, system, and method for direct delivery of a therapeutic to a target site that utilizes the non-Newtonian characteristics of shear thinning and shear thickening to allow easy passage of a therapeutic through a delivery lumen yet facilitate retention of the therapeutic in the target site. The device, system, and method includes increasing the shear rate or shear stress of a non-Newtonian fluid having therapeutic properties thereby increasing or decreasing the viscosity of the non-Newtonian fluid.

The present invention provides an ophthalmic device, and method of use thereof, for an individual wearing an ophthalmic lens to increase ocular surface boundary lubrication. The invention device comprises an ophthalmic lens and a sacrificial mechanism disposed on the ophthalmic lens, wherein the sacrificial mechanism comprises a plurality of surface bound receptors, such as PRG4, hyaluronic acid, and DNA aptamers, that reversibly bound to a lubricating composition comprising a gel forming agent, a surfactant, or a combination thereof, effectively inhibiting or preventing protein and lipid adsorption on the surface of the lens, and mitigate shear stress and reduce the friction between the lens and the ocular surface of the individual in need.

The present invention relates to an improved three-dimensional cell to tissue development process using a specific time varying electromagnetic force, pulsed, square wave, with minimum fluid shear stress, freedom for 3-dimensional spatial orientation of the suspended particles and localization of particles with differing or similar sedimentation properties in a similar spatial region.

A thermal dissipation structure and method are provided which include a heat sink having a surface configured to couple to a surface of an electronic component for facilitating removal of heat from the component. The heat sink surface and the electronic component surface comprise dissimilar materials with different coefficients of thermal expansion. The heat sink surface has a pattern of channels therein which define multiple heat sink substructures. Each heat sink substructure includes a portion of the heat sink surface. The portions of the heat sink surface are coplanar and provide a reduced distance to neutral point across the heat sink surface. When the portions of the heat sink surface are bonded to the electronic component surface, shear stress within the bond is reduced.

Improved thermoelectric assemblies are disclosed, wherein layers of heterostructure thermoelectric materials or thin layers of thermoelectric material form thermoelectric elements. The layers are bound together with agents that improve structural strengths, allow electrical current to pass in a preferred direction, and minimize or reduce adverse affects, such a shear stresses, that might occur to the thermoelectric properties and materials of the assembly by their inclusion.