The invention discloses a manufacturing method of a composite ceramic closed impeller containing a metal framework, and belongs to the field of application of impeller wear-resistant protective coatings. The manufacturing method comprises the first step of preparation of an impeller framework, the second step of preparation of an outer diameter mold and a foaming core mold, the third step of impeller mold combining and assembling operation, the fourth step of pouring equipment connection, the fifth step of pouring material preparation, the sixth step of pouring material vacuumizing operation,the seventh step of material pouring, the eighth step of pouring material curing operation, the ninth step of mold disassembling operation and the tenth step of detail polishing operation. The vacuumizing step is carried out in the pouring material mixing process, and entrained bubbles in the pouring materials are removed before the material pouring. The two sections of processes of heating and curing are carried out after material pouring is finished, the operation difficulty of the material pouring process is reduced, waste material cleaning work is convenient, the personnel shift of the production section can be reasonably arranged, and the manufacturing method has the comprehensive advantages of simple design, stability, reliability, excellent quality and cost economy.