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39results about How to "Prolonged bleeding time" patented technology

Piperazinones, their production and use

The present invention provides compounds and medicines effective for prophylaxis and therapy of various diseases by controlling or inhibiting cell-adhesion. Especially, the compounds of this invention perform platelet aggregation action without remarkable elongation of hemorrhagic period and can be used as a safe and long-acting antithrombotic drug as compared with known substances showing the same activity. Compounds of this invention are piperazinones of the formula
Owner:TAKEDA PHARMACEUTICALS CO LTD

Inhibition of phosphoinositide 3-kinase beta

The present invention relates to selective inhibitors of phosphoinositide (PI) 3-kinase β, use of the selective inhibitors in anti-thrombotic therapy, and a method for screening compounds useful for the new anti-thrombotic therapy by detecting selective inhibitory activity of PI 3-kinase β of the compound. The invention also relates to novel compounds that are inhibitors of PI 3-kinase.
Owner:ASTRAZENECA AB

Novel intrauterine sustained control release drug delivery system and preparation method thereof

The present invention relates to a female intrauterine drug delivery system, and more particularly to a novel intrauterine sustained control release drug delivery system and a preparation method thereof. The present invention provides a novel intrauterine sustained control release drug delivery system and a preparation method thereof, wherein the system has characteristics of short length, light weight, efficiency, and reversibility. The system comprises a sustained control release pipe, a drug core and a tail filament, wherein the sustained control release pipe is wrapped on the external of the drug core, the tail filament is positioned between the sustained control release pipe and the drug core or is accomodated in the middle of the drug core, the drug core is a rod prepared by blending progesterone or an available intrauterine sustained control release drug and a biodegradable polymer, and the sustained control release pipe is made of a silicon rubber. The system of the present invention has characteristics of no stent, no copper ion, safety, practicality, and simple placement technology.
Owner:杨立群

Aorta blocking balloon device based on 18F-FDG detection and positioning

The invention belongs to the technical field of medical instruments, and particularly relates to an aorta blocking balloon device based on 18F-FDG detection and positioning, which comprises a catheter, a balloon is arranged at the front end of the catheter, an injection tube communicated with the balloon penetrates through the interior of the catheter, and an injector communicated with the injection tube is arranged at the rear end of the catheter; before aorta blocking hemostasis is executed, the device can assist in determining the general anatomical orientation of the balloon in the body and increasing the success rate of disposable balloon blocking, and has the following advantages that firstly, the device has lower requirements on the technical ability and experience of first-aid implementers, and can be mastered according to program operation after simple training; secondly, the 18F-FDG is a common medical medicament, the availability and the medication cost can be controlled, and correspondingly, the handheld gamma ray detector for detecting the 18F-FDG is relatively low in cost; the technical operation procedure is simple, and the risk of additionally increasing bleeding time is small; fourthly, the half-life period of 18F is short, and secondary injury to patients is small.
Owner:中国人民解放军火箭军特色医学中心
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