The invention discloses a fastening alternating type massager for preventing deep venous thrombosis of lower limbs. The massager comprises oblique flexible bearing, lifting and packaging apparatus, adjustable attaching type elastic tightening apparatuses, and air-pushing alternating type inverse piezoelectric micro-vibration massage apparatus, wherein the adjustable attaching type elastic tightening apparatuses and the air-pushing alternating type inverse piezoelectric micro-vibration massage apparatus are arranged in the oblique flexible bearing, lifting and packaging apparatus, and the adjustable attaching type elastic tightening apparatuses are arranged on two opposite sides of the air-pushing alternating type inverse piezoelectric micro-vibration massage apparatus. The invention belongs to the technical field of medical prevention exercise apparatuses, and particularly relates to the fastening alternating type massager for preventing deep venous thrombosis of lower limbs, which canbe suitable for users with different leg thicknesses, improves the effect of relieving deep venous blood flow, provides massage services with different massage strengths for the users, and lifts andtightens the lower limbs.