90 results about "Lymphedema" patented technology

A compression garment for selective application for treatment of lymphedema and prevention of local ischemia of tissues at various locations of the body. The garment includes a pair or series of layers of hermetically sealed material, that can capture pressurized air, when applied therein, and is formed through the patterned sealing of the layers of the garment together, at select locations, to form air pockets that can selectively apply isolated points of pressure to the patient's affected area, without disrupting normal vascular and lymphatic functioning. The garment is design cut, for application to various segments of the body, and applies encompassing pressure over the entire affected area, and includes valves that can allow for the injection of measurable air, to the desired pressure points, or its deflation, after treatment. The compression device of this invention may also be formed as a segmented pad or mat, into which pneumatic pressurized air may be applied, at various segments, so as to regulate the amount of pressure applied to the surface of the body that is in contact with the pad or mat of this invention.

A method of body manipulation in furtherance of treating lymphedema is provided. A wrap, adapted to fit about a body extremity and having a trunk region, and limb regions, and a plurality of compartments distributed throughout the regions, is provided and applied to the body extremity. Each of the compartments of the plurality of compartments are capable of selective pressurization and depressurization. The body extremity is prepared for receipt of lymph fluid via a first pressurization and depressurization sequence of select compartments within select regions of the regions of the wrap, and lymph fluid is drained from the body extremity via a second pressurization and depressurization sequence of select compartments within select regions of the regions of the wrap, whereby the lymphatic system is stimulated so as to promote readsorption of pooled lymph fluid within surrounding tissue.

A compression garment for selective application for treatment of lymphedema and related illnesses manifested at various locations of the body. The garment includes a pair or series of layers of hermetically sealed material, that can capture pressurized air, when applied therein, and is formed through the patterned sealing of the layers of the garment together, at select locations, to form air pockets that can selectively apply isolated points of pressure to the patient's affected area, without disrupting normal vascular and lymphatic functioning. The garment is design cut, for application to various segments of the body, and applies encompassing pressure over the entire affected area, and includes valves that can allow for the injection of measurable air, to the desired pressure points, or its deflation, after treatment.

A method of body manipulation in furtherance of treating lymphedema is provided. A wrap, adapted to fit about a body extremity and having a trunk region, and limb regions, and a plurality of compartments distributed throughout the regions, is provided and applied to the body extremity. Each of the compartments of the plurality of compartments are capable of selective pressurization and depressurization. The body extremity is prepared for receipt of lymph fluid via a first pressurization and depressurization sequence of select compartments within select regions of the regions of the wrap, and lymph fluid is drained from the body extremity via a second pressurization and depressurization sequence of select compartments within select regions of the regions of the wrap, whereby the lymphatic system is stimulated so as to promote readsorption of pooled lymph fluid within surrounding tissue.

A compression garment or pad for selective application for treatment of lymphedema evidenced at various locations of the body. The pad includes a pair or series of layers of hermetically sealed material, that can capture pressurized air, when applied therein, and is formed through the patterned sealing of the layers of the pad together, at select locations, to form air pockets that can selectively apply isolated points of pressure to the patient's affected area, without disrupting normal vascular and lymphatic functioning. The pad is design cut, for either use in that matter, or for application as a garment to various segments of the body and can apply pressure over the entire affected area. The pad includes valves that allows for injection of measurable air, to the desired pressure points, or its deflation, after treatment.

The invention provides polynucleotides and genes that are differentially expressed in lymphatic versus blood vascular endothelial cells. These genes are useful for treating diseases involving lymphatic vessels, such as lymphedema, various inflammatory diseases, and cancer metastasis via the lymphatic system.

A compression device (10) comprising an inflatable bladder (12), an optional controller (14), a source of fluidic pressure (16), and a cuff (18) at least partially housing the inflatable bladder and capable of being attached to a body part (20) of a living being. The controller is in fluid communication with the source of fluidic pressure and the inflatable bladder. The controller is capable of maintaining the fluid pressure that the source of fluidic pressure supplies to the inflatable bladder at a constant fluid pressure, even if the body part to which the device is attached decreases in volume. The source of fluidic pressure can be container of compressed fluid, like carbon dioxide. The source of fluidic pressure and the controller can be removably attachable to the cuff. A method of using the device to maintain constant pressure to decrease the volume of a limb or to lessen lymphedema.

Disclosed and claimed are compositions and methods for therapy and / or prevention of lymphedema. The compositions can include an agent that induces development of lymphatic channels or lymphangiogenesis, such as, VEGF-C and / or that which stimulates VEGF-C expression and / or that which stimulates VEGF-C expression or that which stimulates its interaction or that which stimulates other pathways to so stimulate the development of lymphatic channels or lymphangiogenesis or that which stimulates along any point of or any molecules involved in the signal transduction pathway leading to lymphangiogenesis or lymph channel development (and / or vector(s) expressing one or more of these agent(s)). Embodiments can include kits.

A method of body manipulation in furtherance of treating lymphedema is provided. A wrap, adapted to fit about a body extremity and having a trunk region, and limb regions, and a plurality of compartments distributed throughout the regions, is provided and applied to the body extremity. Each of the compartments of the plurality of compartments are capable of selective pressurization and depressurization. The body extremity is prepared for receipt of lymph fluid via a first pressurization and depressurization sequence of select compartments within select regions of the regions of the wrap, and lymph fluid is drained from the body extremity via a second pressurization and depressurization sequence of select compartments within select regions of the regions of the wrap, whereby the lymphatic system is stimulated so as to promote readsorption of pooled lymph fluid within surrounding tissue.

The present invention is directed to methods and compositions that may be used in disrupting the association of smooth muscle cells with lymphatic endothelial cells and in correcting the valvular dysfunction in veins and lymphatic vessels. Such compositions are useful for therapeutic and prophylactic treatment of impaired lymphatic and venous function, particularly for the treatment of lymphedema distichiasis or chronic venous insufficiency.

The present invention comprises methods for detecting, monitoring and treating lymphedema by using imaging devices to generate patient anatomical information from which body part volume measurements or geometries can be derived. Yet further, the present invention comprises methods of fitting compression garments for treatment of lymphedema by using the anatomical measurements derived from the patient anatomical information.

The invention provides methods for detecting lymphedema and methods for managing lymphedema in an individual. The methods of the invention involves utilizing a light sensing device having a video camera, depth sensor and software effective to perform a 3-dimensional scan and generate a three-dimensional digital model of at least a portion of the body from data obtained by the camera and depth sensor, thereby obtaining a three-dimensional digital model of at least a portion of the body from which the size of a select region of the body can be assessed to detect, monitor and / or manage lymphedema. The invention also provides methods to detect and manage lymphedema that involve assessing any combination of size, amount of extracellular fluids, and thickness of the skin at a select region of the body of an individual.

A method of treating a body limb by applying pressure to the limb using a flexible sheet having a plurality of successively connected inflatable chambers.

A patient-friendly medical device is provided for removal of excess fluids from body tissue and is particularly useful to treat soft tissue inflammation, damage, edema and / or lymphedema. The comfortable medical device comprises a composite multilayered assembly that provides a gradient pressure compression device to compress body tissue of a patient in a controlled and graduated manner. The composite multilayered assembly can have an inner and / or outer layer to enhance uniform distribution of compression about the affected portion of the patient and can have flexible intermediate layers with elastomeric components such as foamed chips, foamed pieces, and / or chopped foam that can have a different density and / or size and / or shape to form channels (canals) therebetween to enhance flow of excess fluids from the body tissue of the patient. The channels or canals can create zones of gradient pressure to help move excess fluid from the tissue of the affected portion of the body of the patient.

The invention belongs to the technical field of medicines and in particular relates to a traditional Chinese medicine for treating lymphedema of upper limbs after breast cancer operation and a preparation method thereof. The traditional Chinese medicine for treating the lymphedema of the upper limbs after the breast cancer operation is prepared from the following raw materials in parts by weight: 50-70 parts of cudrania cochinchinensis, 50-70 parts of cassia twig, 50-70 parts of mulberry leaf, 50-70 parts of milkvetch, 20-40 parts of codonopsis pilosula, 11-19 parts of curcuma aromatica, 11-19 parts of Chinese angelica, 20-40 parts of eclipta alba, 16-24 parts of white atractylodes rhizome, 11-19 parts of white paeony root, 6-14 parts of poria cocos, 20-40 parts of salvia miltiorrhiza, 6-14 parts of semen coicis and 50-70 parts of loess doll. The traditional Chinese medicine for treating the lymphedema of the upper limbs after the breast cancer operation has the effects of clearing and activating the channels and collaterals, replenishing blood and activating blood circulation, dissipating stasis and stopping pain as well as inducing diuresis to alleviate edema and has the advantages of high curative ratio and no adverse effect when being used for treating the lymphedema of the upper limbs after the breast cancer operation.

A reduced pressure treatment appliance is provided for enclosing and providing reduced pressure treatment to an object or a portion of an object. In some embodiments, the reduced pressure treatment appliance may be used to treat wounds and other conditions, such as lymphedema, varicose veins, venous insufficiency and stasis, and other infirmities. In other embodiments, the appliance may be used to provide reduced pressure (or vacuum) treatment for non-medical purposes. In some embodiments, the appliance comprises a flexible chamber and a collapsible frame that may be collapsed while the appliance is not in use. In yet other embodiments, the appliance also includes a vacuum system to supply reduced pressure to the volume within the chamber, a pressurized fluid system to inflate the collapsible frame, a drainage system to remove fluids from the appliance, and a treatment port and a forced entry treatment system to introduce fluids and other treatment instrumentalities into the volume within the chamber. In still other embodiments, the chamber is designed for use with distal extremital portions of a body. In further embodiments, the appliance also comprises a semi-permeable liner positioned between the chamber and the portion of a body to be treated. Finally, methods are provided for using various embodiments of the appliance.

Disclosed herein are nucleic acid molecules comprising a nucleotide sequence of sVEGF-2, proteins encoded by those sequences and antibodies that bind to the protein. Also disclosed are methods for inhibiting or enhancing expression or activity of sVEGFR-2 and methods for inhibiting graft rejection, particularly cornea graph rejection. Also described are methods for inhibiting lymphangiogenesis and lymphatic endothelial cell proliferation by administering an effective amount of sVEGFR-2 and methods for treating lymphedema by inhibiting the activity of sVEGFR-2.

A method of treating venous insufficiency and lymphedema in an individual by placing pulsatile, localized pressure or compression on deep veins and subcutaneous tissue by inflating and deflating volume-changing members implanted within the individual. A method of potentiating venous circulation, by placing pulsatile, localized pressure that compresses the deep veins by expanding and contracting volume-changing members located between the fascia and muscular compartment, such that the increase in volume from the volume-changing members is transferred to deep veins, and augmenting the effects of muscle contractions around the deep veins and improving blood circulation. A method of potentiating lymphatic circulation. A method of potentiating venous and lymphatic circulation. A pulsatile pressure implant including at least one volume-changing member in electronic connection with an electronic-controlled microprocessor.

A patient-friendly medical device is provided for removal of excess fluids from body tissue and is particularly useful to treat soft tissue inflammation, damage, edema and / or lymphedema. The comfortable medical device comprises a composite multilayered assembly that provides a gradient pressure compression device to compress body tissue of a patient in a controlled and graduated manner. The composite multilayered assembly can have an inner and / or outer layer to enhance uniform distribution of compression about the affected portion of the patient and can have flexible intermediate layers with elastomeric components such as foamed chips, foamed pieces, and / or chopped foam that can have a different density and / or size and / or shape to form channels (canals) therebetween to enhance flow of excess fluids from the body tissue of the patient. The channels or canals can create zones of gradient pressure to help move excess fluid from the tissue of the affected portion of the body of the patient.

Disclosed herein are nucleic acid molecules comprising a nucleotide sequence of sVEGF-2, proteins encoded by those sequences and antibodies that bind to the protein. Also disclosed are methods for inhibiting or enhancing expression or activity of sVEGFR-2 and methods for inhibiting graft rejection, particularly cornea graph rejection. Also described are methods for inhibiting lymphangiogenesis and lymphatic endothelial cell proliferation by administering an effective amount of sVEGFR-2 and methods for treating lymphedema by inhibiting the activity of sVEGFR-2.

The invention belongs to the technical field of medical devices and particularly discloses a depth scanning and information analysis-based upper limb lymphedema monitoring system. The system comprises three parts including a scanning platform, a software analysis system and a cloud platform, wherein the scanning platform obtains depth and color data of upper limb of a patient suffering from edema and is controlled to run by the software analysis system; the software analysis system performs automatic grading diagnosis on the edema through depth scanning, image processing and information analysis; a doctor performs intervention treatment on the patient through a diagnosis result; the cloud platform stores the data of the scanning platform and the software system, and creates a personalized archive for the patient; and the doctor can perform remote medical treatment on the patient according to the cloud platform. According to the system, the multifunctionality and high efficiency of edema monitoring can be realized; edema assessment is performed by adopting multi-feature fusion analysis, and comprehensive analysis is performed through multiple features such as space, color, texture and the like, so that the system is superior to a current measurement form for a single index of the edema; and the system is low in cost, small in occupied space and convenient to use, and is of important significance for popularization and use in families and hospitals.

The invention relates to the technical field of a medical appliance, in particular to a far infrared radiation treatment instrument for treating limb lymphedema. The far infrared radiation treatment instrument is characterized by comprising an upper box body and a lower box body, wherein each of the upper box body and the lower box body is provided with a semicircular cavity; the semicircular cavities are matched to form a limb thermal therapy space; each of the upper box body and the lower box body is provided with a far infrared heating tube; the far infrared heating tubes are uniformly arranged along the peripheral direction of the thermal therapy space; the cavity wall surface of each semicircular cavity is a light reflecting surface; each far infrared heating tube is a far infrared heating tube for emitting low-temperature far infrared rays. The far infrared radiation treatment instrument has the advantage that the far infrared radiation treatment instrument with the advantages of safety, good curative effect, no side effect and convenience in operation is provided.

The present invention identifies genes whose gene products are differentially expressed lymphedema tissues, particularly cutaneous tissue involved in whole organ response to lymphedema. The invention provides methods for diagnosing or assessing an individual's susceptibility to lymphedema. Also provided are therapeutic methods for treating a patient or methods for prophylactically treating an individual susceptible to lymphedema. Additionally, the invention describes screening methods for identifying agents that can be administered to treat individuals that have or at risk of developing lymphedema.

A method treating the symptoms of tendonitis, arthritis, capsulities, lymphedema and ganglion cysts in the arm of a user which involves the steps of placing a pressure imparting device around selected portions of the user's arm and applying controlled pressure to the discrete areas of the skin directly overlying the selected portions. The pressure imparting device includes two discrete compression plates that are placed around selected portions of the user's arm and are drawn toward one another to apply bipolar transaxial compression of equal magnitude simultaneously to discrete areas of the skin directly overlying the selected portions.

The present invention relates to the field of undergarments for women, and more particularly to a wrap for lactation suppression, for use by a non nursing mother during the postpartum period to reduce the accumulation of breast milk and associated pain, as well as for mastectomy and Lymphedema patients, and those who have undergone breast augmentation, reconstruction, and reduction surgeries. The present invention, described and claimed in detail below, can be used with or without a user's own support garment such as a bra or sports bra. It is comprised of a larger interior component with velcro for attachment, and an out elastic strap component for securing a good tight fit and adjustability.

In a foot bandage for compression therapy of lymphedema on the foot, with a sole section, side sections connected laterally to sole section, which are joined to each other at least in a section that comes to lie above the heel when the foot bandage is applied, and at least a distal tab section made of an elastic material, which can be wound around the instep and fastened to a side section in order to exert compression on the foot, in which the distal tab section or each tab section has at least one pull tab on which fasteners are arranged, a proximal compression band made from elastic material fastenable removably to the side sections is provided. The compression band has at least a first fastener and is attached to the side sections by means of the first fastener above the heel, when the foot bandage is applied in area.