77results about How to "Improve morbidity" patented technology

Medical diagnostic apparatus and methods are disclosed. Ultrasound radiation pressure selectively modulates a target area within a body. One or more pulses of radiation containing temporally correlated groups of photons are generated. The photons are characterized by two or more different wavelengths that are selected to have specific interaction with a target chromophore. The two or more different wavelengths are also selected to have substantially similar scattering cross-sections and anisotropy parameters in the target and its surroundings. The pulses of radiation are injected into the body proximate the target area being modulated by the radiation pressure field. Photon groups at each of the different wavelengths that are backscattered from the target area are detected in temporal coincidence. Time-gated background-free amplification of the return signal is used to exclude photons which could not by virtue of their arrival time have interacted with the radiation-pressure-modulated target. Photon groups are selected with a modulation component at the modulation frequency of the radiation pressure modulation field, or at a harmonic of the modulation frequency. From the arrival rate of the detected temporally correlated photon pairs or multiplets, chemical information about the target area, such as an oxygenation or pH level can be inferred. Cardiac output may be computed from measurements of venous and / or arterial oxygenation using this technique.

An all-inside double-socket ACL reconstruction technique, according to which a femoral socket and a closed tibial socket are provided to accommodate retrograde fixation of at least one graft (for example, a semitendonosus allograft) within the sockets. The closed tibial socket is formed by using a retrograde drill device provided with a retrograde drill cutter detachable from a retrograde drill guide pin. The femoral socket may be formed by the retrograde drill method or by a conventional method, and may be carried out before or after the formation of the tibial socket. The graft is secured in the knee by employing a transversal implant, or by employing an interference screw, and / or a continuous loop / button construct.

The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and / or iatrogenic condition of the colon.

A method for treating or preventing spontaneous preterm birth in pregnant women and improving neonatal morbidity and mortality. The method includes administering to a pregnant woman in need thereof an effective amount of progesterone sufficient to prolong gestation by minimizing the shortening or effacing of her cervix. Treatment and prophylaxis with progesterone in pregnant women having symptoms of short cervix has been clinically shown to increase neonatal health.

A method for treating or preventing spontaneous preterm birth in pregnant women and improving neonatal morbidity and mortality. The method includes administering to a pregnant woman in need thereof an effective amount of progesterone sufficient to prolong gestation by minimizing the shortening or effacing of her cervix. Treatment and prophylaxis with progesterone in pregnant women having symptoms of short cervix has been clinically shown to increase neonatal health.

A total artificial spinous process (spino)-laminar prosthesis (TASP-LP) including a body having a portion forming a spinous process extending away from the body, a first lamina portion extending from a first side of the body, and a second lamina portion extending from a second side of the body, wherein the first lamina portion and the second lamina portion are disposed on opposite sides of the spinous process.

An apparatus for treating tissue in a tissue treatment area includes a heater that does not contact the tissue. The apparatus may be attached to the skin of a person to form a treatment volume about the tissue to be treated. The heater, supported at the layer, is held near the tissue to be treated, out of contact with the tissue. The apparatus includes a controller to cause the heater to raise the temperature of tissue in the tissue treatment area to a temperature in a range from a pretreatment temperature to 38° C. The controller may include means that cause the heater to operate over a therapeutic sequence, that cycle the heater on and off, that provide selectable average temperature values, that cause the heater to operate over an average temperature range, that cause the heater to operate at an average temperature over a therapy cycle, or that cause the heater to operate at an average temperature over a therapeutic sequence.

A non-contact controllable heater wound covering and method having a peripheral sealing ring covered by a layer to which is attached a heater and this assembly is attached to the skin with an adhesive so that the heater is held proximate the wound area in a non-contact position. The layer and peripheral sealing ring together define a treatment volume proximate the wound. The wound covering includes a programmable active heater control and the sealing ring may dispense water to control the humidity of the treatment volume. One form of active heat is an electrical resistive filament in variable geometric shapes providing versatility in application of heat to different types of wounds and wound area geometries. Another form of active heat is the transfer of a heated gas to the wound covering.

A device is proposed to progressively reduce the hemodynamic cardiac symptoms of congestive heart failure as well as those induced by dilated cardiomyopathies. This device affords progressive diastolic ventricular control by offering a method for percutaneous access and adjustments of its gas filled bladders surrounding the heart. After opening the pericardium, the device is not attached to the heart muscle but may be anchored to the pericardial sac. The device actually extends primarily around the heart from below the atrio-ventricular canal to the cardiac apex. Between the device exterior, made of non-elastic material and the epicardium, two independent elastic bladders or chambers provide variable compressive diastolic support to the right and left ventricles, while allowing adequate blood flow to the anterior and posterior descending epicardial branches of the coronary arteries and veins. Progressive hemodynamic increases in diastolic pressures for the right and left ventricles can be individually and repeatedly monitored by pressure gauges and an inert gas separately injected or removed in the enclosed chest through self-sealing access ports. These ports are subcutaneously implanted in the left anterior axillary line and connected by thin tubes across the 4th or 5th intercostal spaces to the pericardial bladders or chambers described above.

The invention provides, in some aspects, a system for implementing a rule derived basis to display image sets. In various embodiments of the invention, the selection of the images to be displayed, the layout of the images, as well as the rendering parameters and styles can be determined using a rule derived basis. In an embodiment of the present invention, the user is presented with images displayed based on their preferences without having to first manually adjust parameters.

The present invention relates to methods of stimulating stem cell proliferation and engraftment, and methods of preventing and / or treating disorders associated with radiation exposure, chemotherapy, exposed to chemical / biological warfare agents, and / or any other insults affecting rapidly proliferating tissues in a body, or one or more symptoms thereof. In particular, the present invention provides methods of stimulating stem cell proliferation and / or engraftment and methods of preventing and / or treating disorders associated with one or more insults affecting rapidly proliferating tissues in a body (e.g., radiation exposure, chemical and / or biological insults) or one or more symptoms thereof by administering to a subject a composition comprising a Fibroblast Growth Factor-20 (FGF-20) protein, or its fragments, derivatives, variants, homologs, analogs, or a combination thereof.

the invention discloses a space optical camera having on-orbit self-diagnosis and compensation functions, which belongs to the space optical obtaining field. The camera comprises a space camera optical system and a phase difference wavefront detection unit, wherein the space camera optical system is in the form of Cassegrain, coaxial three-mirror, off-axis three-mirror and the like optical systems; and the phase difference wavefront detection unit comprises a focal multistage spliced detector, an out-of-focus multistage spliced detector, a focal detector interface, an out-of-focus detector interface, a data acquisition module, a data preprocessing module, a computing module, a storage module and a control interface. The space optical camera having the on-orbit self-diagnosis and compensation functions is capable of reducing the requirements of a high-performance space optical system for design, structure, thermal control and the like without adding other extra high-precision wavefront measuring device, thereby realizing high-accuracy on-orbit diagnosis and compensation imaging of the space optical system.

The invention is directed to a laterally inserted spinous process plating device and a method for installing the device using a minimally invasive procedure. The device includes a partially threaded bolt as well as a contralateral and ipsilateral fixation plates, a deployment nut, a lag nut and a locking nut. Each fixation plate includes a pair of wing portions that are pivotally connected to one another to facilitate installation. The each of the fixation plates includes anchoring elements.

The invention discloses a method using an improved regularization method to restrain difference global positioning system (DGPS) integer ambiguity ill-condition. The method using the improved regularization method to restrain the DGPS integer ambiguity ill-condition comprises the steps of (1), collecting observation data of a global positioning system (GPS) carrier phase, building a DGPS carrier phase double-difference observation equation; (2) obtaining a floating point solution of DGPS integer ambiguity and a corresponding variance-covariance matrix based on a least square method according to the DGPS carrier phase double-difference observation equation; (3) and using a two-step solution to build a regularization matrix in a Tikhonov regularization algorithm, obtaining a corresponding regularization parameter according to a DFP quasi-newton method, processing the variance-covariance matrix by using the obtained Tikhonov regularization algorithm, restraining ill-condition of the DGPS integer ambiguity, and at last obtaining accurate integer ambiguity. According to the method using the improved regularization method to restrain the DGPS integer ambiguity ill-condition, the improved Tikhonov regularization algorithm is used for restraining the problem of the ill-condition in the DGPS integer ambiguity, the method using the improved regularization method to restrain the DGPS integer ambiguity is beneficial for obtaining the accurate integer ambiguity, and high-accuracy positioning and attitude measurement of DGPS can be achieved.

An alarm capable of determining the flow time remaining of irrigation fluid is disclosed. It is also contemplated that the device can detect a partial or complete blockage in the system or empty fluid bag and alert medical personnel locally or remotely as required. The device is capable of calculating the time remaining before the CBI irrigation fluid in the irrigation fluid bag reaches a pre-set level that necessitates changing the bag or the actual time of day or night when the irrigation will be approaching the critical level. Additionally, the user can be alerted to the CBI irrigation fluid in the irrigation fluid bag reaching a pre-set level that necessitates changing the bag before the fluid level becomes critical.

The invention is directed to non-invasive methods of detecting gastric cancer in an individual in need thereof comprising determining an expression level of inter-alpha-trypsin inhibitor heavy chain H3 (ITIH3) in the individual and comparing the expression level to a control, wherein an increase in the expression level of ITIH3 in the individual compared to the control is indicative of gastric cancer in the individual.

A combination cancer therapy based upon catechins, the major biologically active polyphenol in plant products, including green tea extract, and one or more chemotherapeutic agents. A common complication of cancer chemotherapy is neutropenia, and in spite of advances in its prophylactic management is a major cause of risk for the development of serious microbial infections leading to increased morbidity and mortality in both humans and animals. The use of cathechins such as those found in green tea (Camellia sinensis), including but not limited to epigallocatechin gallate (EGCG) as nontoxic adjuvant to aid in the prevention of opportunistic microbial infections in patients undergoing immunosuppressive chemotherapy is a novel application. Also contemplated are methods using catechins to ameliorate the immunosuppressive effects of cancer chemotherapy by administering the compound to a patient in need thereof.

The invention discloses a lung respiration monitoring system based on magnetic detection electrical impedance imaging. By means of an excitation source module, excitation signals are introduced to the chest cavity of an imaging body through a plurality of pairs of excitation electrodes bonded to the measured imaging body; a measurement module is composed of a series of measurement coils and used for measuring the magnetic induction intensity of an induced magnetic field caused by exciting current around the chest cavity; a control module is used for controlling the signal excitation and magnetic field measurement process during the whole respiration monitoring; an image reconstructing module obtains the image change of electrical inductance distribution of the chest cavity in the respiration process according to an electrical impedance image reconstruction algorithm on the basis of magnetic field distribution data. According to the system, the measurement coils of any number can be placed in the space around the chest cavity of the imaging body, limitation of a traditional electrical impedance imaging system on measurement information is changed, the system has the advantages of being high in measurement precision, high in speed and reliability and free of injuries to a human body, more importantly, information amount is increased by means of a magnetic field measurement mode, and therefore the electrical impedance reconstructing ill conditioning is changed, the resolution ratio of electrical impedance (or impedance spectrum) images is increased, and the image reconstruction quality is improved.

Cosmetic / pharmaceutical compositions for promoting hair growth and / or retarding hair loss, and / or for increasing the mean diameter of strands of hair and / or decreasing the heterogeneity thereof, and / or for increasing hair density, and / or for improving the quality and / or the appearance of a head of hair, and / or for inducing repigmentation of the hair, contain thus effective amounts of intimate admixture of vitamin A, vitamin C, vitamin E, and zinc and selenium values.

The invention provides a method for detecting the accuracy of a CT photon counting type detector, relating to the technical field of medical treatment equipment. The method comprises the following steps: building a CT scanning system by virtue of an x-ray bulb tube, a triangular prism-shaped double-material mold body and a common flat panel detector, and scanning so as to obtain a first group of data; removing the mold body, and carrying out empty scanning so as to obtain a second group of data; constructing a linear equation set based on an attenuation transmission principle according to the two groups of data, and solving to obtain a first x-ray dispersion energy spectrum; replacing the common flat panel detector with a to-be-detected photon counting type detector, removing the mold body, and carrying out empty scanning so as to obtain a second x-ray dispersion energy spectrum; and making comparison on the two dispersion energy spectra, wherein when the error is within a certain range, the accuracy of the photon counting type detector meets the requirements. According to the method, the triangular prism-shaped double-material mold body is arranged, and the energy spectrum measurement is carried out by virtue of two attenuation substances based on the attenuation transmission principle, so that the morbidity of a to-be-solved linear equation set is fundamentally and effectively improved; and the structure of the mold body is simple, the scanning number of times is few, the wasting of resources is effectively avoided, and the reliability is high.

Methods are described for treating inflammatory bowel disease in animals, including humans. Specific avian polyclonal antibodies directed to proinflammatory cytokines (such as IL-6 and TNF) are shown to have a beneficial effect in animal models predictive of human therapy for the treatment of colitis, including Crohn's disease.

The invention discloses an electric impedance imaging system with an open electrode scanning mode. Exciting electrodes introduce an excitation signal emitted from an excitation source into an imaging body; a first measurement electrode and a second measurement electrode carry out one-dimensional or two-dimensional scanning along the surface of the imaging body between the exciting electrodes; a measurement device collects measurement information of the imaging body through the first measurement electrode and the second measurement electrode, and transmits the measurement information to a microprocessor, and the microprocessor processes the measurement information and rebuilds an electric impedance distribution image of the imaging body. According to the electric impedance imaging system disclosed by the invention, limitation of the surface area of the imaging body to the mounting quantity of the first measurement electrode and the second measurement electrode is overcome, the density of arranged measurement electrodes is greatly improved by arrangement of the first measurement electrode and the second measurement electrode; useful information is increased; the ill-condition of rebuilding the electric impedance is improved; the imaging resolution ratio of the electric impedance (or impedance spectroscopy) is improved and the rebuilding quality of the image is also improved.

The subject matter described herein provides non-invasive tape stripping methods for the collection of a skin sample. The tape stripping method includes applying and removing at least one adhesive tape, provided that a skin sample is adhered to the adhesive tape after removal. The at least one adhesive tape is supplied in an adhesive skin sample collection kit. The adhesive skin sample collection kit further comprises a sample collector and instructions for use sheet.

The subject matter described herein provides non-invasive tape stripping methods for the collection of a skin sample. The tape stripping method includes applying and removing at least one adhesive tape, provided that a skin sample is adhered to the adhesive tape after removal. The at least one adhesive tape is supplied in an adhesive skin sample collection kit. The adhesive skin sample collection kit further comprises a sample collector and instructions for use sheet.

The invention discloses a scanning radar forward-looking imaging method based on spatial embedded mapping, which includes the following steps: converting an azimuth resolution improving problem into amatrix solving problem on the basis of echo range pulse compression and range walk correction; analyzing the singular value distribution of an antenna measurement matrix using the theory of singularvalue decomposition, determining the order of a spatial embedded matrix under the premise of retaining the information of the antenna measurement matrix to be maximum, and generating a spatial embedded matrix; using the spatial embedded matrix to extract the information of the antenna measurement matrix, reconstructing the antenna measurement matrix and an echo signal, reducing the order of the matrix, increasing the matrix-irrelevant characteristic, and improving the pathological property of the antenna measurement matrix; reducing the order of the antenna measurement matrix according to a data model of spatial embedded mapping, so as to reduce the computational complexity; and based on the least squares principle, calculating the scattering coefficient of a target, and quickly imaging the target in azimuth at high resolution.

The present invention involves the use of transcription factors including Tbx5, Mef2C, Hand2, myocardin and Gata4 to reprogram cardiac fibroblasts into cardiomyocytes, both in vitro and in vivo. Such methods find particular use in the treatment of patients post-myocardial infarction to prevent or limit scarring and to promote myocardial repair.

The invention provides a multistep effective method for finite element model updating. Based on the conventional model updating method, updated parameters are arranged, classified, optimized and selected by building sensitivity information array. Then the finite low-order modal information is obtained by employing the structural vibration measurement to update the finite element model step by step. The method has the advantage of solving the problem of ill conditioning of a one-time solution to the model updating equation sets in conventional method, therefore reducing the impact on updating solution from measuring error, giving physical significance to the updating.