The invention provides a multi-element mixed refrigerant which comprises 3,3,3-trifluoropropene and propane. The molar percentage concentration of 3,3,3-trifluoropropene is 5-85%, and the molar percentage concentration of propane is 15-95%. The multi-element mixed refrigerant is suitable for a stand-alone compressing and refrigerating system, has the ozone depletion potential (ODP) of zero, and cannot harm the atmospheric ozone layer and has quite small global warming potential (GWP) after being used for a long time. In addition, since the multi-element mixed refrigerant comprises 3,3,3-trifluoropropene and propane, for a two-element mixture, azeotropic refrigerating working substances can keep the stable evaporating working state under the boiling point, and convenience is provided for the injection of the refrigerant and the maintenance of the refrigerating system. In addition, the multi-element mixed refrigerant has a small pressure ratio, and the efficiency of a compressor can be effectively improved by reducing the pressure ratio.