65results about How to "Improve the effect of diagnosis and treatment" patented technology

The invention discloses a micro-needle patch capable of intelligently regulating blood glucose and a preparation method thereof, and belongs to the field of biomedicine. An intelligent micro-needle part of the micro-needle patch capable of adjusting blood glucose is filled with a medicine for intelligently adjusting blood glucose, and the medicine comprises a carrier material, glucose response sensitive switch factors and medicine molecules. A micro-needle of a micro-needle template is filled with a hydrogel solution containing the medicine through a vacuumizing and centrifugation method; re-centrifugation is carried out, a base of the micro-needle patch is prepared by using the hydrogel solution without the medicine, solidification of the hydrogel material is carried out through a propermethod, and after drying, the micro-needle patch is stripped from the template to obtain the micro-needle patch for intelligently adjusting the blood glucose. The micro-needle patch can puncture skin,insulin is intelligently released in the body according to the blood glucose concentration, and the blood glucose level is intelligently adjusted. According to the micro-needle patch, painless and intelligent response type blood glucose regulation is realized, and diabetes diagnosis and treatment integration is expected to be guided.

The invention discloses a 3D printing microneedle patch for intelligent blood glucose regulation and a preparation method thereof, belonging to the biomedical field. The 3D printing microneedle patchof the invention is mainly made of photosensitive material with good biocompatibility, and comprises two parts of a substrate and a microneedle array, wherein the microneedle array comprises a plurality of conical microneedles, and the microneedles contain medicaments for intelligently regulating blood sugar, and the medicaments include carrier materials, glucose-responsive sensitive switching factors and medicaments molecules. The 3D printing microneedle patch of the invention is mainly made of photosensitive material with good biocompatibility. Firstly, the three-dimensional model of micro-needle patch is built by using modeling software, and the model is imported into the printing software of 3D printer. Then the 3D printing technology of photocuring is used to solidify the photosensitive material solution containing photoinitiator and drug according to the structure of the three-dimensional model of the micro-needle patch to obtain the 3D printing micro-needle patch. The microneedle patch of the invention can puncture the skin and intelligently release the loaded insulin according to the blood glucose concentration in the body so as to intelligently regulate the blood glucose level. The invention realizes painless, intelligent and responsive blood glucose regulation.

The invention belongs to the technical field of image information processing and discloses a method for constructing a 3D printed individual orthopeadic implant and enhancing the biomechanics of the 3D printed individual orthopeadic implant. The method comprises the following steps: firstly, preprocessing a CT image; secondly, cutting the CT image; thirdly, reconstructing a typical three-dimensional skeleton model, taking the typical model as a template, and performing three-dimensional model repairing and reconstructing treatment on other skeletons based on the template; fourthly, studying askeleton anatomical reduction-oriented digital grid registration algorithm; designing an individual surgical template optimized by a screw-setting scheme; optimizing the geometric pattern matching andmechanical performance of an individual artificial joint prosthesis; printing the three-dimensional model, and performing three-dimensional printing-based orthopeadic implant treatment. The method has important theoretical significance and clinical application value in shortening the orthopeadic preoperative planning cycle, improving the implanting efficiency and mechanical performance of individual implants, reducing surgical time and surgical injury and promoting orthopeadic implant industrial development.

The invention discloses a multifunctional contrast agent of oxygen carrying liquid fluorocarbon. The multifunctional contrast agent is of a spherical shell-core structure; the core is prepared from liquid fluorocarbon and indocyanine green. The invention aims at solving the technical problems to provide the multifunctional contrast agent of oxygen carrying liquid fluorocarbon and the preparation method. The multifunctional contrast agent has high biological safety and stability, and is used for the multi-mode nanometer contrast agent guided breast cancer light treatment.

The invention discloses an oral panoramic film decayed tooth depth recognition method based on deep learning. The method comprises the following 5 steps: preprocessing data; segmenting the image; constructing a model; performing feature extraction; and performing classification and identification. According to the method, the convolutional neural network is adopted to identify the decayed teeth, automatic identification of the decayed teeth in the oral cavity panoramic film is realized, and result export of automatic decayed tooth depth identification can be realized. Visual fatigue easily caused by long-term viewing of image data by medical staff is solved, diagnosis and treatment capacity and working efficiency are improved in an assisted mode, medical resource requirements are reduced,and medical efficiency is improved.

The invention discloses a clinical research and follow-up fusion system and method. The system comprises the components of an information acquisition unit which is configured for acquiring historicalmedical record information of a patient and acquiring current health data of the patient based on follow-up information of the patient; an information extracting unit which is configured for extracting a clinical diagnosis-and-treatment plan for treating the affected disease of the patient from the historical medical record information, and extracting a current symptom of the patient from the current health data of the patient; a processing unit which is configured for determining a reoccurrence probability of the affected disease of the patient according to the current symptom of the patientand a pretrained predicting model, and in response to a fact that the reoccurrence probability is higher than a preset threshold, analyzing the clinical diagnosis-and-treatment plan for determining apotential hazard factor which causes the reoccurrence; and a pushing unit which is configured for pushing the potential hazard factor that causes the reoccurrence to a doctor client for assisting a doctor in adjusting the clinical diagnosis-and-treatment plan and pushing a further diagnosis notification to a patient terminal. The system according to the invention facilitates optimization of the diagnosis-and-treatment plan by the doctor to the patient.

The invention discloses a preparation method and application of a 3D print microacupuncture needle paster, and belongs to the field of biomaterials and biological manufacturing. A dual-spray-head melting deposition shaping FDM 3D printer is used, a spray head is used for printing a base of the microacupuncture needle paster, and the other spray head is used for printing a columnar array of the microacupuncture needle paster, wherein the columnar array contains insulin medicines which can intelligently respond to and adjust blood sugar. After the base and the columnar array are obtained, a slide is in contact with the top end of the columnar array, then the top end is stretched to a preset distance to produce a needle point of the microacupuncture needle, cross-linking shaping is performed,and after dewatering and drying are completed under natural state, a microacupuncture needle array paster having certain mechanical properties and containing responsiveness medicines is formed. The microacupuncture needle paster can puncture skin, can intelligently respond according to blood sugar concentration in vivo, can intelligently release loaded medicines, and can intelligently adjust thelevel of the blood sugar. In a 3D print microacupuncture needle manner, painless intelligent response type blood sugar adjustment capable of realizing skin puncture can be realized, and the 3D print microacupuncture needle paster hopefully guides diagnosis and treatment integration of diabetes.

The invention discloses an artificial intelligence learning processing system based on clinical data. The system comprises a data storage and management module and an artificial intelligence module. The system is characterized in that the data storage and management module stores a large amount of diagnosis-and-treatment data; the artificial intelligence module calls the data in the data storage and management module and performs analysis processing on the diagnosis-and-treatment data according to a specific algorithm, thereby realizing generation data classification, treatment effect evaluation, statistics and sequencing. Furthermore a result is stored in the data storage and management module. The system realizes intelligent management and application of the clinical data and greatly improves diagnosis-and-treatment capability and working efficiency.

The invention discloses a hepatoma cell-specific aptamer and a preparation method thereof. The hepatoma cell-specific aptamer comprises at least one of an H2c aptamer, an H4c aptamer and an H5b aptamer. The method comprises the following steps: a first library and a primer are synthesized; the first library and a target cell are incubated; nucleic acid that is not combined with the target cell is separated and purified, a first template is obtained, and asymmetric amplification is performed on the first template to obtain a second library; the second library and an inverse screening cell are incubated; nucleic acid combined with the inverse screening cell is separated and purified, a second template is obtained, and asymmetric amplification is performed on the second template to obtain a third library; operation is repeated until a twelfth template is obtained, symmetric amplification is performed on the twelfth template, an amplification product is obtained, cloned and sequenced, and single aptamers are obtained through separation; secondary structures of the single aptamers are analyzed through simulation, the binding rate is determined, and the aptamer is picked out. The aptamer prepared with the method can recognize hepatoma cells and hepatoma tissue in a high-specificity manner.

The invention provides an auxiliary stroke diagnosis and treatment robot system based on artificial intelligence and internet technologies by organically integrating the artificial intelligence technology and the internet technology with the clinical diagnosis and treatment of stroke. The effect and efficiency of diagnosing and treating stroke by clinicians are greatly improved, and a new idea, anew method and a new mode are provided for solving the conflict of supply and demand imbalance of medical resources for stroke in China.

The invention discloses an osteoarthritis cartilage targeting gadolinium-based magnetic resonance imaging contrast agent and a preparation method thereof. The contrast agent comprises Gd2CO3 nanoparticles. The surface of the Gd2CO3 nanoparticles is coated with a dopamine shell, and the surface of the dopamine shell is loaded with cartilage targeting polypeptide through end-modified polyethylene glycol, and the amino acid sequence of the cartilage targeting polypeptide is DWRVIIPPRPSA. The osteoarthritis cartilage targeting gadolinium-based magnetic resonance imaging contrast agent achieves osteoarthritis cartilage specific targeting and MRI imaging. According to test verification, the agent shows good T1-MRI imaging capability, good in vitro chondrocyte targeting capability and effective cartilage targeting capability in mice.

The invention organically integrates the artificial intelligence technology and the internet technology with cerebral stroke language rehabilitation, and provides a cerebral stroke language rehabilitation robot system based on artificial intelligence and the internet technology, so that the effect and efficiency of clinical cerebral stroke language rehabilitation are greatly improved, and a new thought, a new method and a new mode are provided for solving the contradiction between cerebral apoplexy language rehabilitation related medical resource supply and demand imbalance in China.

The invention belongs to the technical field of medical research, and discloses a method for detecting chronic obstructive pulmonary disease. The method comprises the following steps of evaluating a general item of collected patients; evaluating abdominal muscle endurance by sit-ups; using Leicester Cough Questionnaire (LCQ) assessment to assess cough-related quality of life of patients; using afatigue effect scale (FIS) to evaluate the fatigue sensation of the subjects; patients were assessed with Beck Depression Inventory (BDI). The results are analyzed statistically. The method finds a significant relationship between the level of depression and the physical, social, psychological dimension and overall quality of life and cough, improves the knowledge, diagnosis and treatment abilityof the clinician for the complications of chronic obstructive pulmonary disease complicated with anxiety and depression, and contributes to improving the condition of the patient and shortening the treatment time of the patient.

The invention relates to the technical field of medical equipment, in particular to a video laryngoscope with a display switching key. The video laryngoscope with display switching key provided by the present invention includes a laryngoscope main body, the laryngoscope main body includes a handle and a display device rotatably connected to one end of the handle, and is not limited by the patient's position during intubation; the handle is provided with a power supply, The control unit, image and video processing device, and storage device integrate real-time video and image transmission and storage functions, which is convenient for on-site and remote teaching; the other end of the handle is connected to the first camera component, and there are two interfaces on the handle, one of which is The interface is connected with the second camera component, and the other interface is used to connect the smart device; the handle is provided with a switch key connected to the control unit, and the control unit responds to the command of the switch key, so that the display device displays the first camera component and the second camera component Switching back and forth between the two states is convenient for viewing the condition of the patient's larynx and lungs during the treatment, improving the effect of diagnosis and treatment.

The invention relates to an accurate intelligent medical digital system based on a blockchain. The system comprises a user module, a medical supplier module, a blockchain module, an accurate intelligent medical module and a telemedicine module. The user module is used for storing the information of a user and a local medical record and defining a blockchain intelligent contract. The medical supplier module is used for providing an access platform for serving the user for a medical service supplier. The blockchain module is used for storing and reading a user medical record in a distributed mode. The accurate intelligent medical module is used for intelligently analyzing and excavating accurate medical data. The telemedicine module is used for providing a communication platform between theuser and a doctor.

The invention relates to an intelligent composite stone needle energy field generator based on a new concept. The intelligent composite stone needle energy field generator is characterized by comprising an intelligent human meridian and acupoint measuring and controlling device, a far infrared composite stone needle energy field generator and an ultrasonic pulse composite stone needle energy field generator at least, wherein the intelligent human meridian and acupoint measuring and controlling device is connected with the far infrared composite stone needle energy field generator and the ultrasonic pulse composite stone needle energy field generator respectively; human meridian and acupoint biological electric field signals are collected by a meridian and acupoint biological electric field signal detection sensor of the intelligent human meridian and acupoint measuring and controlling device in real time, firstly sent to a meridian and acupoint biological electric field signal CPU to be processed, and then sent to a meridian and acupoint biological electric field balance controller to be modulated into feedback signals, the feedback signals are used for controlling the far infrared composite stone needle energy field generator and the ultrasonic pulse composite stone needle energy field generator respectively, and therefore synchronous sensory control over detection and balance of the human meridian and acupoint biological electric field signals is achieved. According to the intelligent composite stone needle energy field generator, real-time measuring and controlling means having the characteristic that treatment is carried out according to symptoms are combined with efficient treatment means organically, so that therapeutic effects of common physiotherapeutic massagers are improved obviously.

The invention discloses a patient online inquiry system for an internet hospital, a user authority module comprises a user module, a role module and an authority module, and a display module comprises a merchant module and a doctor module. The inquiry module comprises a hospital guide module, a user self-diagnosis module, an inquiry communication module, an inquiry payment module, a prescription making module and an evaluation module, and the personal module comprises a user basic information module, a user order module and a discount module.According to the invention, a patient can be converted from a preliminary diagnosis process to a pre-diagnosis process to a definite diagnosis process in an actual online inquiry process; the disease of the patient is determined step by step in a staged inquiry mode, the accuracy of the diagnosis result of the actual disease of the patient by a doctor is ensured, meanwhile, the diagnosis and treatment effect of online inquiry of the patient is also improved, traditional medical treatment and the Internet technology are organically combined, the patient can be subjected to online inquiry, data can run more ways, and the patient does not take lots of time to hospitals.

The invention provides a device for treating cancers through an electric field and a using method of the device. The device comprises a control module, an electric field generator, a pair of electrode patches, an electric field recognition module, an electric field receiver and a magnetic field array. The electrode patches are installed on the two outer surfaces of the tumor position of the human body and used for receiving the electric field of the magnetic field array. The electric field recognition module is fixedly attached to one electrode patch to recognize the electric field intensity and direction of the current electrode acting on the human body in the magnetic field array. The electrode patches and the electric field identification module are connected with the control module; the electric field generator is connected with each electrode of the magnetic field array to generate a treatment electric field; and the control module judges whether the electric field intensity and direction of the current electrode acting on the human body meet treatment requirements, and if not, re-scanning is carried out, and switching is conducted to an electrode meeting the treatment requirements. Based on the device, the invention further provides a device using method. The wearable free movement mode is adopted, cancer is treated through an electric field, and the treatment position cannot deviate.

The invention provides a cognitive function screening method, system and equipment based on an eye movement test and a medium. The method comprises the following steps: acquiring data of a patient to be screened; constructing a cognitive function screening data set according to the to-be-screened patient data, and dividing the cognitive function screening data set into a training set and a test set according to a preset proportion; inputting the training set into a plurality of preset classifiers for k-time cross validation training, and integrating the plurality of preset classifiers through a soft voting method to obtain a cognitive function screening model; and inputting the test set into the cognitive function screening model for testing to obtain a screening result, so that rapid quantitative analysis can be carried out based on eye movement data of multiple disease types and multiple symptoms, intelligent screening of cognitive impairment is realized, the cognitive impairment screening efficiency and accuracy are improved, the diagnosis and treatment ability of doctors with insufficient diagnosis and treatment experience is improved, and the diagnosis and treatment experience of the doctors is improved. Effective guarantee is provided for early discovery and early treatment of diseases, and the medical workload and the long-term social burden are further relieved.

The invention provides a multifunctional internal medicine diagnosis and treatment bed, and relates to the field of internal medicine medical instruments. The multifunctional internal medicine diagnosis and treatment bed comprises a bed plate, a diagnosis and treatment mechanism and an auxiliary mechanism; support columns are arranged at four corners of the bed plate; a box body is further arranged at the bottom of the bed plate; a screw rod is rotatably connected to an output end of a servo motor, and a telescopic rod is fixedly connected to the top of a base; a supporting plate is fixedly connected to the top of a rotating block; and a diagnosis device is installed at the top of the supporting plate. According to the multifunctional internal medicine diagnosis and treatment bed, the servo motor is used for controlling the lead screw to rotate, so that the base moves in an inner cavity of the box body, the supporting plate above the telescopic rod is driven to move along with the base, and therefore medical staff can conveniently diagnose and treat a patient through the diagnosis device; the supporting plate can rotate at will, so that convenience is provided; the arranged supporting rod can provide multiple sets of hanging hooks; and a drawer type collecting layer is arranged, so that necessary medical supplies can also be stored, the functions of the whole diagnosis and treatment bed are relatively complete, and the diagnosis and treatment effect of the internal medicine department is improved.

The invention discloses a clinical instrument for an obstetrics and gynecology department, and relates to the technical field of medical instruments. The clinical instrument comprises a lying plate, afixed platform and a telescopic bracket; the lying plate is mounted on the upper surface of the fixed platform; the telescopic bracket is fixedly connected to the bottom end of the fixed platform; the surface of the fixed platform is connected with multiple mounting blocks; the bottom surface of the lying plate is buckled with the mounting blocks; a sliding rail is arranged on the upper surface of the lying plate; a side baffle is mounted at the upper end of the lying plate; and the bottom end of the side baffle is connected with a sliding block. The slide block is matched with the slide railin position; the sliding block is in sliding fit with the sliding rail; the bottom end of the fixed platform is connected with an inner groove; scrolls are mounted on two opposite side surfaces of the inner groove; one end of the scrolls is connected with a crank, the bottom end of the inner tank is provided with a liquid storage tank, one surface of the inner side of the liquid storage tank is connected with a heater, and the surface of one side of the liquid storage tank is connected with a liquid guide pipe. The lying plate has a detachable structure on the upper surface of the fixed platform, can be detached and lifted in the actual use process, is not limited by the bottom supporting platform and is more flexible to use.

The invention provides an infrared ray decayed tooth detection apparatus. The apparatus comprises a handle [1], an infrared ray induction apparatus [2] is arranged on the handle, the infrared ray induction apparatus [2] and a video apparatus [3] are linked, a center control apparatus [4] is arranged, and a prompting apparatus [5] is arranged at the rear segment of the handle, wherein the infrared ray induction apparatus [2] is used for scanning and detecting periphery of teeth, the video apparatus [3] is used for monitoring abnormity of tooth color, related detection information is transmitted to the center control apparatus [4] for analyzing, and the prompting apparatus [5] emits a prompting sound, in order to promote the tooth is decayed and abnormal; an illumination component is arranged on the video apparatus [3] for providing auxiliary illumination when ambient light is dark; the illumination component is an LED illumination component; the video apparatus [3] is connected to a computer network for sharing information, and the information can be enlarged and observed by a computer screen when needed; and the infrared ray scan can be used for inspecting the position of the decayed tooth, in order to assist diagnosis and treatment of doctors and improve diagnosis and treatment effects.

A method and apparatus for identifying a cardiac orientation in a chest X-ray film includes the steps of extracting a lung tissue profile from the chest X-ray film, calculating a slope of each point of the lung tissue profile, determining a cardiac apex position based on the calculated slope, and the like. The apparatus comprises a memory and a processor. The invention can automatically identify the cardiac apex position in the chest X-ray plain film image through an automatic device such as a computer, thereby further identifying the cardiac orientation, avoiding the need of judging and identifying by observing the chest X-ray plain film one by one manually, improving the identification efficiency and reducing the error rate. Further, after the cardiac orientation is recognized, the corresponding warning message can be automatically given according to the recognition result to alert the medical personnel, so as to improve the diagnosis and treatment effect. The invention is widely applied to the field of image recognition.

The invention discloses an anxiety disorder comprehensive diagnosis and treatment platform based on a Chinese zither. The platform comprises a detecting reference comparison unit, a searching database unit, a treatment unit, a questionnaire module, a calculating and reference comparison module, a diagnosis conclusion report module, a selecting module and a treatment unit, wherein the detecting reference comparison unit, the searching database unit and the treatment unit use a local server as a data processing center; the local server is provided with a touch display screen; the detecting reference comparison unit comprises an intelligent monitoring wristband; the questionnaire module, the calculating and reference comparison module and the diagnosis conclusion report module are placed in the local server; the diagnosis conclusion report module transmits data to the searching database unit; the searching database unit comprises a storage module placed in the local server; the selecting module selects Chinese zither programs, treatment time and treatment parameters according to searching comparison results of the storage module; and the treatment unit comprises a playing and treatment module which plays the selected Chinese zither programs or plays the selected Chinese zither programs in real time according to the Chinese zither programs selected by the selecting module. By the anxiety disorder comprehensive diagnosis and treatment platform based on the Chinese zither, existing anxiety disorder diagnosis and treatment service is greatly improved, the structure is efficient and reasonable, the diagnosis and treatment effect is improved, and the anxiety disorder comprehensive diagnosis and treatment platform based on the Chinese zither is wide in application, easy to implement, safe and reliable.

The embodiment of the invention provides a proximal femur operation positioning and orientating system and a manufacturing method thereof.The system comprises an attaching device, an orientating device and a depth limiting device; the attaching device is used for being attached to the proximal femur and manufactured according to the anatomical form of the proximal femur, and the attaching device comprises an attaching portion attached to the proximal femur and a connecting portion connected with the orientating device; the orientating device is used for indicating the direction of a lesion of a patient and comprises a guide plate, and the guide plate is connected with the connecting portion and provided with a guide hole for indicating the direction of the lesion; the depth limiting device is used for limiting the depth that an operative instrument enters the lesion of the patient in the direction indicated by the orientating device, connected with the guide plate and arranged to be capable of enabling an operator to be able to perform at least one of the following operations of arriving at the lesion, building an operation channel and placing an implant through the guide hole under assistance of the depth limiting device.

System and method for accessing and treating a patient's cerebrospinal fluid. The system comprises a device with at least one implantable single or multilumen catheter, configured for placement along a patent's cerebrospinal fluid pathway, with at least one domed subcutaneous reservoir and / or pump connected to the catheter(s). The device can also be equipped with control circuitry and controllable valves. The devices allow for drug administration and / or simultaneous, bidirectional cerebrospinal fluid access and exchange. The catheter(s), may be coupled with medical probes that transmit sensor data to the device's processor, which can be configured transmit and receive data and instructions. The catheters may also be configured with guide devices to facilitate implantation. Various configurations, from single dome to multiple dome devices are taught, along with various applications such as epidural and other cerebrospinal drug administration, and various medical diagnostic applications.

The invention discloses a preparation method and application of a 3D printed microneedle patch, which belongs to the field of biological materials and biomanufacturing. The FDM 3D printer uses double nozzles for fused deposition molding. One nozzle is used to print the base of the microneedle patch, and the other A single nozzle prints a columnar array of microneedle patches containing insulin drugs that respond intelligently to regulate blood sugar. After the substrate and the columnar array are obtained, contact the top of the columnar array with a glass slide, and stretch it to a predetermined distance to produce a microneedle tip, which is cross-linked and formed. After dehydration and drying in the natural state, a microneedle with certain mechanical properties and responsive Microneedle array patch for drugs. The microneedle patch can puncture the skin and respond intelligently in the body according to the blood sugar concentration, intelligently release the contained drugs, and intelligently regulate the blood sugar level. Through 3D printing microneedles, painless, skin-punctured, intelligent and responsive blood sugar regulation can be realized, which is expected to guide the integration of diagnosis and treatment of diabetes.

The invention provides a system and a grouping method for carrying out risk assessment on aerobic bacterial vaginitis by using gram staining smears and an establishment method of a prediction model adopted by the system and the grouping method. The systems and methods are based on the combination of vaginal secretion gram staining smears and clinical characteristics, can quickly and conveniently perform aerobic bacterial vaginitis risk assessment, and can provide a homogenized and standardized data basis for artificial intelligence reading of genital tract infection.