130results about How to "Improve solution stability" patented technology

In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (a) and include tautomers, solvates, prodrugs, esters, and deuterates thereof, and pharmaceutically acceptable salts of said compounds, tautomers, solvates, prodrugs, esters, and deuterates, wherein each of R¹, R², R³, R⁴, R⁵, R⁹, ring A, ring B, ring C, m, n, p, q, -L₁-, -L₂-, L₃-, and L₄- is selected independently and as defined herein. The compounds of the invention have, surprisingly and advantageously, improved solution stability. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use in treating pathologies associated with amyloid beta (Aβ) protein, including Alzheimers Disease, are also disclosed.

The invention provides a multi-antenna attitude determining method based on a Beidou system. With the establishment and improvement of the Beidou satellite regional navigation system, the use of the Beidou satellite system for high-precision attitude determination has become one of the hot spots in the field of navigation. The method is based on the realization of the Beidou receiver hardware embedded platform and based on the three-antenna carrier phase data simultaneously observed by the Beidou receiver, the double-difference model is constructed and finally the high-precision attitude information is obtained. The present invention mainly makes innovation and improvement of the satellite selection strategy, the cycle slip detection method, the rough error rejecting and fuzziness calculation method, the base line verification method in the attitude determination flow. The method is highly modularized, supports various platforms, is particularly suitable for the embedded receiver platform, and has a wide application prospect.

In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula: (I) and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomeros and said stereoisomers, wherein each of ring A, ring B, ring C, R², R³, R⁴, m, n, p, and -L₁- is as defined herein. The novel compounds of the invention may be useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including Alzheimer's disease, are also disclosed.

A method is provided for preparing spray dried powder containing vancomycin hydrochloride. The method comprises providing a vancomycin hydrochloride solution with a chromatographic purity of at least 95%, adding an excipient to the vancomycin hydrochloride solution to form a mixture solution of the vancomycin hydrochloride solution and the excipient, concentrating the mixed solution of the vancomycin hydrochloride solution and the excipient to form a 20% to 30% vancomycin concentrate, filtering the vancomycin concentrate to form a final filtrate, and spray drying the final filtrate to form a spray dried vancomycin hydrochloride powder with EP impurity B level of not more than 1.5%.

The invention discloses an optical push-broom satellite in-orbit stepwise geometric calibration method based on a probe element direction angle. A probe element direction angle-based in-orbit geometric calibration model and a stepwise calibration resolving method are included. According to the method, a probe element direction angle model is used as a camera calibration model; calibration parameters comprise internal calibration parameters and external calibration parameters; and the external calibration parameters are resolved first and then the internal calibration parameters are resolved by using a stepwise calibration method, so that the condition that a reliable calibration result cannot be obtained due to strong correlation existing between the calibration parameters is avoided. By the effective optical push-broom satellite in-orbit geometric calibration method, in-orbit geometric calibration can be effectively performed on an optical push-broom satellite, and the geometric quality of image products is improved. Practice proves that the calibration method is feasible and effective, and the calibration result is stable, reliable and high in precision.

Methods for enhancing biocidal efficacies and product stability of lens care solutions comprising packaging such solutions in containers fabricated from poly(ethylene terephalate).

The invention relates to an antireflective coating composition comprising a crosslinker and a crosslinkable polymer capable of being crosslinked by the crosslinker, where the crosslinkable polymer comprises a unit represented by structure (1):

A-B_n  (1)

where A is a fused aromatic ring and B has a structure (2),

where R₁ is C₁-C₄alkyl and R₂ is C₁-C₄alkyl

The invention further relates to a process for forming an image using the composition.

An aspect of the present invention relates to an optical information recording medium comprising a recording layer on a surface of a support, wherein the surface of the support has pregrooves with a track pitch ranging from 50 to 500 nm, the recording layer comprises an azo metal complex dye in the form of a complex of at least one azo dye denoted by general formula (1) and at least one metal ion:

wherein, in general formula (1), Q¹ denotes an atom group forming a ring with two adjacent carbon atoms and a carbon atom bonded to —N═N-group, G¹ denotes a heterocyclic group or carbocyclic group, and R¹ denotes an alkyl group, alkenyl group, alkynyl group, aryl group, or heterocyclic group.

The present invention relates to a novel absorbing antireflective coating composition comprising a novel crosslinkable polymer comprising at least one repeat unit (A) having structure (1), at least repeat (B) unit having a structure (2), and at least one repeat unit (C) having structure (3)

where D is a direct valence bound or C(R₁)(R₂) methylene moiety where R₁ and R₂ are independently H, C₁-C₈ alkyl, C₃-C₂₄ cycloalkyl or C₆-C₂₄ aryl; Arⁱ, Arⁱⁱ, Arⁱⁱⁱ and Ar^iv are independently phenylenic and naphthalenic moiety, R₃ and R₄ are independently hydrogen or C₁-C₈ alkyl; and R₅ and R₆ are independently hydrogen or C₁-C₈ alkyl; and a solvent. The invention also relates to a process for forming an image using the novel antireflective coating composition.

In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (I): and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomeros and said stereoisomers, wherein each of W, Z, R^1H, R², R³, R⁴, ring A, ring B, m, n, p, and -L₁- is as defined herein. The novel compounds of the invention have surprisingly been found to exhibit properties which are expected to render them advantageous as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including Alzheimer's disease, are also disclosed.

Provided are a reducing electroless silver plating solution and a reducing electroless silver plating method using the silver plating solution, the reducing electroless silver plating solution being capable of preventing decomposition of silver in the plating solution thereby to maintain stability of the solution and also being capable of preventing excessive roughening of an underlying metal or the like thereby to form a plating film having good film characteristics and a good appearance. The reducing electroless silver plating solution according to the present invention comprises a water-soluble silver salt and a reducing agent, wherein cyanide ions in a concentration of 0.006×10⁻³ mol/L to 12.5×10⁻³ mol/L are contained.

A metal complex represented by the following formula (1):

wherein R¹ to R⁶, R⁸ and R¹¹ to R²⁰ represent a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, an alkylthio group, an aryl group, an aryloxy group, an arylthio group, an arylalkyl group, an arylalkoxy group, an arylalkylthio group, an acyl group, an acyloxy group, an amide group, an acid imide group, an imine residue, a substituted amino group, a substituted silyl group, a substituted silyloxy group, a substituted silylthio group, a substituted silylamino group, a monovalent heterocyclic group, a heteroaryloxy group, a heteroarylthio group, an arylalkenyl group, an arylalkynyl group, a substituted carboxyl group or a cyano group;

• • Z¹ to Z⁵ represent —C(R*)═ or a nitrogen atom, wherein R* represents a hydrogen atom or a substituent, provided that at least two of Z¹ to Z⁵ are nitrogen atoms;
  • m represents 1 or 2.

The invention discloses a multi-baseline PolInSAR vegetation parameter inversion method considering the temporal decoherence factor. The method comprises the following steps: 0, introducing the temporal decoherence factor into a RVoG model to obtain a RVoG expansion model considering the temporal decoherence factor; 1, carrying out processing and polarimetric interferometry processing on a multi-baseline polarimetric interferometry SAR (Synthetic Aperture Radar) image of vegetation to obtain a multi-baseline multi-polarization multiple correlation coefficient observed value; 2, setting and calculating the vegetation parameter inversion initial value of the RVoG expansion model; 3, selecting one of N baselines as a reference baseline, and considering that the influence of the temporal decoherence factor does not exist; and 4, matching the observed value with the RVoG expansion model, building an observation equation, and finally performing vegetation parameter inversion by a nonlinear iterative algorithm according to the parameter initial value obtained above. The method can improve the accuracy of vegetation parameter inversion, and is easy to implement.

A heat-resistant film includes a film substrate and a heat-resistant slip layer. The heat-resistant slip layer is disposed on one surface of the film substrate and contains a binder and a slip additive, which is a higher fatty acid metal salt composition containing a free higher fatty acid in an amount of 3 to 30 wt % and a metal salt of a higher fatty acid. With this heat-resistant film, a good heat-resistivity and slipperiness are obtained even when the slip additive is contained in the heat-resistant slip layer in relatively small amounts. The slip additive improves the solution stability of the coating composition used to form the heat-resistant slip layer. Preferably, the free higher fatty acid is stearic acid and the metal salt of higher fatty acid is aluminum stearate.