The invention relates to the communication field, and discloses a method and device of sheet processing for multi-slot resources. The method comprises the following steps: aiming at each slot in a frame period, a first node uniformly maintains slot state vectors in which slot state information of each slot stores, sends FI to other nodes in self-use slot in each frame period, receives FI sent by other nodes in non-self-use slot in each frame period, and updates the slot state information corresponding to each slot in the slot state vectors maintained locally according to the received FI. Therefore, requirements of multi-slot resource operation of car networking multiple business types are met, the multi-slot resources can be effectively processed and coordinated, one slot state vector sheet is adopted to conduct node multi-slot resource processing, the storage capacity is small, the load processing is uniform, and overmuch operating load can not be brought to a system.