The invention relates to the technical field of pharmaceutical tests, in particular, relates to an efficient mixing and dissolving device for pharmaceutical test analysis, and overcomes the defects that the internal volume of a stirring device cannot be changed according to the quantity of prepared reagents and solid particles are difficult to dissolve by stirring alone; the efficient mixing and dissolving device comprises a support frame, and a connecting shaft is welded on the inner side of the support frame; a connecting plate is connected to one end of the connecting shaft through a bearing, a mixing tank is fixedly welded to one side of the connecting plate, a screw rod is connected to the bottom of the mixing tank through threads, a handle is clamped to one end of the screw rod, an adjusting plate is connected to the other end of the screw rod through a rotating shaft, and a heating plate is mounted on the inner side of the top of the adjusting plate; the outer surface of the adjusting plate is sleeved with a sealing gasket; the top of the mixing tank is fixed with a motor by bolts, and the output end of the motor is sleeved with a sleeve shaft. According to the mixing and dissolving device for the pharmaceutical tests, the internal volume of a mixing container can be adjusted according to the use amount required by preparation of a test solvent, and a better stirring effect is achieved.