Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

32 results about "Tracheal ring" patented technology

Degradable artificial trachea stent and production method thereof

The invention relates to a degradable artificial trachea support frame and a manufacturing method thereof, which belong to the technical field of biological medicine. The support frame is characterized by being weaved into a circular pipe shape by polyp-dioxygen cyclohexanone monofilaments or polyglycolic acid monofilaments; the longitudinal axles of a tracheal wall transversely surround a pipe-shaped annulet formed by weaving the double-layered monofilaments at intervals; the monofilaments on the inner layer of the tracheal wall are bond uniformly; collagen is uniformly covered on the surfaces of the monofilaments; and chitosan is covered on the collagen in sequence. The manufacturing method comprises the following steps: weaving the circular pipe-shaped annular support frame; dipping the support frame into 2 percent of collage solution and drying; coating chitosan solution on the surface of the inner layer; and drying for standby. After the invention is executed, the stimulation of patches to human tissues is reduced and the anti-infectious capacity is strong, so as to be beneficial to reconstruct tracheas; a double-layer structure can accommodate the support frame for rehabilitating tracheal rings and achieve double rehabilitations in aspects of physiological anatomy and function of the defective tracheas; and the coating layer of the chitosan is arranged on the inner layer, so as to be beneficial to the creeping rehabilitation of tracheal endothelium.
Owner:唐华 +3

Bougie Device

A bougie device for guiding insertion of an endotracheal tube into an airway of a person, comprises an elongate body of shape memory and self-lubricating material, for example Teflon™. Accordingly no lubrication is required for insertion into the airway for ease of cleaning and sterilizing for reuse. Also, the amount of curvature of the overall rod as well as an angle of the tip of the rod can be adjusted due to the shape memory characteristics of the body to accommodate a particular patent's airway. The body can also be suitably sized to have vibration transmission characteristics such that a contact with one end of the bougie device with tracheal rings of the patient can be felt by a user.
Owner:HARMS STEFAN +2

Percutaneous dilatational device

InactiveUS20130255694A1Reduce traumaReduce trauma to tissuesRespiratorsDilatorsDilatorTracheal wall
The present invention relates to a medical device for performing surgery in the body using a percutaneous dilatational procedure, one embodiment of which is a percutaneous dilatational tracheostomy (PDT) device having a dilator with a non-uniform surface profile that is optimized to the relevant anatomy in order to reduce, uniformly distribute, and ensure uniform, or constant temporal derivative of, dilatational force throughout dilation. This serves to reduce trauma to the patient, specifically producing a reduction of anterior tracheal wall compression, posterior wall laceration / perforation, and tracheal ring fracture that may subsequently lead to subglottic suprastomal stenosis.
Owner:LIFESERVE INNOVATIONS

Dilatation system for a medical device

The present invention relates to a dilatation system for a medical device, in particular where the insertion of a tubular structure (e.g. cannula, catheter or drainage tube) is required. The dilatation system is ideally used for tracheostomy procedures, such as Percutaneous Dilating Tracheostomy (PDT). This minimally invasive surgical device enables to open a gap between the first tracheal rings and to introduce a tracheostomy tube in the trachea of a patient. The present invention also relates to a method inserting a tubular structure into a patient for example a tracheostomy tube in the trachea of a patient.
Owner:GUERRA ROMANO

Trachea spreading forceps

The invention relates to the technical field of medical appliances, in particular to trachea spreading forceps which comprise a left forceps body, a right forceps body and a self-locking mechanism, wherein the left forceps body comprises a left forceps handle, a left forceps neck and a left forceps head, the right forceps body comprises a right forceps handle, a right forceps neck and a right forceps head, the left forceps neck of the left forceps body is connected with the right forceps neck of the right forceps body by a hinged shaft, and the self-locking mechanism is arranged between the left forceps handle and the right forceps handle. The trachea spreading forceps are characterized in that the outer surfaces of the left forceps head and the right forceps head are cambered surfaces, the inner surfaces are smooth surfaces, and the left forceps head and the right forceps head are respectively provided with transverse teeth to enhance the friction between the trachea spreading forceps and tracheal rings so as to achieve the locating effect. By using the structure, the trachea spreading forceps in the invention have the advantages of novel structure, low operation risk, high success rate and the like, are convenient for operation, and can relieve pain of patients.
Owner:王文一

3D printed embeddable double-layer PCL (polycaprolactone) slow-degradation tissue engineering tracheal stent with incomplete tracheal ring and application of stent

PendingCN107981954AHas growth potentialMaintain expectoration abilityAdditive manufacturing apparatusTracheae3d printInsertion stent
The invention relates to a PCL (polycaprolactone) slow-degradation tracheal stent. The stent comprises an outer stent and an inner stent, wherein the outer stent is a hollow C-shaped circular tube, the inner stent is a hollow circular tube, a hollow C-shaped ring is arranged on the outer surface of the outer stent, and the inner stent is embedded in the outer stent. The invention further providesa slow-degradation tissue engineering trachea and an application thereof. The tracheal stent has the advantages as follows: the tracheal stent is completely bionic in terms of organizational structure, the outer layer is tracheal cartilage, and the inner layer is ciliated columnar epithelium, tracheal toughness is achieved, expectoration capacity is maintained, and the incidence of infection aftertransplantation can be reduced; moreover, the tracheal ring is incomplete, has growth potential and can be applied to minor organisms. The tracheal stent can be made into any diameter, and can meet individualized requirements. The PCL stent can be degraded in vivo completely and slowly and is non-toxic to bodies.
Owner:SHANGHAI CHILDRENS MEDICAL CENT AFFILIATED TO SHANGHAI JIAOTONG UNIV SCHOOL OF MEDICINE

Simulator for practicing surgery or procedures involving the neck and airway and method of use thereof

PendingUS20200410898A1Educational modelsHyoid bonePrevertebral fascia
The present disclosure provides a medical training simulation apparatus for training medical professionals, emergency medical support personnel, military personnel, parents or families of persons who have or will be undergoing neck or airway surgery, or any other persons requiring a simulator for learning the anatomy or practicing procedures or surgery of the neck and / or airway. The apparatus may include a simulated base that may be free standing or may rest on a mannequin and may have a hole for accessing the simulated airway, simulated skin, simulated fat, simulated lymph nodes, simulated neck musculature, simulated arteries and veins with simulated blood therein, simulated thyroid gland, simulated parathyroid glands, simulated laryngeal and tracheal cartilage including the hyoid bone, thyroid cartilage, cricoid cartilage, tracheal rings, epiglottis and arytenoid cartilages, mucosa, recurrent laryngeal nerves, trachealis muscle, esophagus and prevertebral fascia. The apparatus may include alteration or addition of one or more anatomical parts to simulate congenital or acquired anomalies. One or more parts of the simulation apparatus may be disposable or replaceable.
Owner:AWESIM MEDICAL CORP

Method for establishing animal in-vitro tracheal model for evaluating inflammatory response induced by tobacco mainstream smoke and evaluation method

The invention relates to a method for establishing an animal in-vitro tracheal model for evaluating inflammatory response induced by tobacco mainstream smoke and an evaluation method, and belongs to the technical field of cigarette hazard assessment. The method for establishing the animal in-vitro tracheal model comprises the following steps: 1) separating a tracheal ring; 2) culturing the tracheal ring obtained in the step 1) in vitro; and 3) exposing the tracheal ring cultured in the step 2) to a flue gas condensate for 1 to 24 hours. The evaluation method of the inflammatory response induced by the tobacco mainstream smoke comprises selection of evaluation indexes and division of evaluation criteria; and evaluation of the degree of the inflammatory response. The method has the followingadvantages: 1) the detection method of the tracheal inflammation after smoke exposure has high efficiency; 2) the detection method of the tracheal inflammation after smoke exposure has good repeatability and system stability and high accuracy; and 3) the use range is wide. The method can be applied to in vitro exposure models of cigarette mainstream smoke, sidestream smoke, ambient flue gas and other smoke aerosols.
Owner:ZHENGZHOU TOBACCO RES INST OF CNTC +1

3D printing incomplete tracheal ring embeddable double-layered PLLA tissue engineering tracheal stent and its application

PendingCN107854195AHas growth potentialMaintain expectoration abilityTracheae3d printTracheal tube
The invention relates to a 3D printing incomplete tracheal ring embeddable double-layered PLLA tissue engineering tracheal stent and its application. The 3D printing incomplete tracheal ring embeddable double-layered PLLA tissue engineering tracheal stent comprises a PLLA degradable tracheal stent of which outer layer is provided with an incomplete tracheal ring, and a PLLA degradable tracheal stent of which inner layer is free from the incomplete tracheal ring; the PLLA degradable tracheal stent of which outer layer is provided with the incomplete tracheal ring is composed of an outer layer PLLA degradable tracheal stent and an incomplete tracheal ring; the side face of the outer layer PLLA degradable tracheal stent is provided with a bracket notch penetrated through the pipe wall and several incomplete tracheal rings; one penetrated tracheal ring notch is arranged on the incomplete tracheal ring; the PLLA degradable tracheal stent of which inner layer is free from the incomplete tracheal ring is embedded in the pipe of the PLLA degradable tracheal stent of which outer layer is provided with the incomplete tracheal ring. The 3D printing incomplete tracheal ring embeddable double-layered PLLA tissue engineering tracheal stent has the advantages of achieving complete simulation, and keeping the tracheal flexibility as well as the sputum excretion ability, reducing occurrence rate of infection after transplanting; the tracheal stent can be applied to juvenile body; the tracheal stent can be degraded in the body and is free from toxic and harm to the body.
Owner:SHANGHAI CHILDRENS MEDICAL CENT AFFILIATED TO SHANGHAI JIAOTONG UNIV SCHOOL OF MEDICINE

Method for preparing sedum sarmentosum extract and use thereof for preparing medicine for relaxing airway smooth muscle

InactiveCN109954017AEfficient relaxation of airway smooth muscleRelieve airway obstructionRespiratory disorderPlant ingredientsSedum sarmentosumEthyl acetate
The invention provides a method for preparing sedum sarmentosum extract and use thereof for preparing medicine for relaxing airway smooth muscle. The sedum sarmentosum extract includes at least one ofan ethanol extract of sedum sarmentosum, a petroleum ether extract of sedum sarmentosum, an ethyl acetate extract of sedum sarmentosum, a n-butanol extract of sedum sarmentosum, and a residual water-phase concentrate after extraction and separation. In the present application, through the detection of isolated tracheal ring muscle tension in experimental mice and Ca<2+> detection in airway smoothmuscle cells, the sedum sarmentosum extract is a highly effective drug for relaxing airway smooth muscle, and the relaxation is caused by blocking LVDCCs and activating calcium channels such as BKCa.The above research results can confirm that sedum sarmentosum extract has the ability to relieve airway obstruction of asthma patients and can be used in the preparation of drugs for relaxing airwaysmooth muscle.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES

Introducer for Surgical Airway Catheters

In one embodiment, an introducer has a round handle; a first curved, flattened (i.e., oval) section connected to the handle; a first straight, unflattened (i.e., circular) section connected to the first curved section; a second curved, flattened section connected to the first straight section; and a last straight, unflattened section connected to the second curved section. The curved, flattened sections allow the introducer to unbend in the anterior-posterior direction to enable a user to introduce a tube or other airway catheter into a surgical airway. The major axis of the oval sections is equal to the diameter of the circular sections, substantially preventing side-to-side bending of the introducer. A rounded distal end provides tactile feedback resulting from palpation of the patient's anterior tracheal rings to confirm proper insertion of the introducer, while tenting of the skin indicates improper insertion.
Owner:LEVITAN RICHARD M

Application of extract from sophora alopecuroides in preparation of medicines for relaxing airway smooth muscle

InactiveCN110025660AEfficient relaxation of airway smooth muscleRelaxes airway smooth muscleRespiratory disorderPlant ingredientsLaboratory mouseAirway smooth muscle
The invention discloses application of an extract from sophora alopecuroides in preparation of medicines for relaxing the airway smooth muscle. Detection on the muscle tension of tracheal rings isolated from a laboratory mouse discovers that the extract from sophora alopecuroides is a medicinal material with an efficient effect for relaxing the airway smooth muscle, which indicates that sophora alopecuroides is a source for new efficient medicines for preventing and treating asthma. The extract from sophora alopecuroides can be used for relieving the symptom of airway obstruction when an asthma patient is attacked, and has a great popularization value.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES

Application of diacerein in relaxation of preshrunk tracheal smooth muscles and treatment of asthma

InactiveCN110787157ARelieve symptoms of blockageEfficient relaxationOrganic active ingredientsRespiratory disorderBiologyEx vivo
The invention relates to an application of diacerein in relaxation of preshrunk tracheal smooth muscles and preparation of a medicine for treating asthma, which belong to the field of medicines. The in-vitro tracheal ring muscle tension of an experimental mouse is detected, the diacerein has the effect of efficiently relaxing tracheal smooth muscles, especially can relax high-potassium induced airway smooth muscle preconstriction and acetylcholine induced airway smooth muscle preconstriction, and is expected to be applied to relieving the symptom of airway obstruction during attack of asthma patients.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES

Application of lalang grass rhizome ethyl acetate part extract in preparation of medicine for relaxing pre-contracted tracheal smooth muscles

The invention relates to the technical field of medicines, and in particular relates to application of a lalang grass rhizome ethyl acetate part extract in preparation of a medicine for relaxing pre-contracted tracheal smooth muscles. By detecting the tension of the isolated tracheal ring muscle of an experimental mouse, it is found that the lalang grass rhizome ethyl acetate part extract has theeffect of efficiently relaxing abnormally contracted tracheal smooth muscles; and it is indicated that the lalang grass rhizome ethyl acetate part extract is expected to be applied to relieving asthma. A basis is provided for developing the application of the lalang grass rhizome ethyl acetate part extract in preparation of the medicine for relaxing the pre-contracted tracheal smooth muscles.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES

Vibration detector and vibration detection method

The invention discloses a vibration detector and a vibration detection method. The vibration detector comprises a vibration assembly and a control assembly connected with the vibration assembly. The vibration assembly comprises a shell, a vibration motor arranged in the shell and a vibration head connected with the shell, wherein the vibration motor is connected with the control assembly; the side, away from the shell, of the vibration head is of a curved-surface-shaped structure. The curved-surface-shaped structure comprises transition arc surfaces located at two ends of the vibration head, and concave arc surfaces which are in smooth connection with the transition arc surfaces at the two ends and are externally tangent to the transition arc surfaces. The vibration detector disclosed by the invention is designed according to a special anatomical structure of a neck tracheal ring, so the vibration detector is matched with the neck trachea and the anatomical structure, the contact surface is not too large or too small, other tissues of the neck are not stimulated, the test result is accurate, cough sensitivity objective evaluation indexes based on physical stimulation are obtained,adverse reactions are avoided, and the compliance degree of a subject is higher.
Owner:THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIV (GUANGZHOU RESPIRATORY CENT) +1

An in vitro animal trachea model establishment method and evaluation method for evaluating tobacco mainstream smoke-induced inflammatory response

The invention relates to a method for establishing an animal in-vitro tracheal model for evaluating inflammatory response induced by tobacco mainstream smoke and an evaluation method, and belongs to the technical field of cigarette hazard assessment. The method for establishing the animal in-vitro tracheal model comprises the following steps: 1) separating a tracheal ring; 2) culturing the tracheal ring obtained in the step 1) in vitro; and 3) exposing the tracheal ring cultured in the step 2) to a flue gas condensate for 1 to 24 hours. The evaluation method of the inflammatory response induced by the tobacco mainstream smoke comprises selection of evaluation indexes and division of evaluation criteria; and evaluation of the degree of the inflammatory response. The method has the followingadvantages: 1) the detection method of the tracheal inflammation after smoke exposure has high efficiency; 2) the detection method of the tracheal inflammation after smoke exposure has good repeatability and system stability and high accuracy; and 3) the use range is wide. The method can be applied to in vitro exposure models of cigarette mainstream smoke, sidestream smoke, ambient flue gas and other smoke aerosols.
Owner:ZHENGZHOU TOBACCO RES INST OF CNTC +1

Application of rhizoma alismatis extract in preparation of drug for relaxing airway smooth muscle

InactiveCN109620897AEfficient relaxation of airway smooth muscleRelieve symptoms of airway obstructionRespiratory disorderPlant ingredientsAirway smooth muscleAnesthesia
The invention discloses the application of a rhizoma alismatis extract in the preparation of a drug for relaxing the airway smooth muscle. It is found that the rhizoma alismatis extract has an efficient function of relaxing the airway smooth muscle through the detection of the isolated tracheal ring muscle tension of an experimental mouse, can be used for alleviating the symptom of airway obstruction during asthmatic attack of a patient, and has great promotion value.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES

Application of Senecio scandens extract in preparation of medicine for relaxing airway smooth muscles

InactiveCN111012814AEfficient relaxation of airway smooth muscleRelieve symptoms of airway obstructionRespiratory disorderPlant ingredientsNew medicationsPharmaceutical drug
The invention discloses application of a Senecio scandens extract in the preparation of a medicine for relaxing airway smooth muscles. Research finds that the Senecio scandens extract is found to be amedicine with an efficient airway smooth muscle relaxing effect by detecting the tension of the isolated tracheal ring muscle of an experimental mouse, which indicates that the Senecio scandens is asource for developing an efficient new medicine for preventing and treating asthma, and can be applied to relieving the symptom of airway obstruction when an asthma patient is attacked. The research of the invention finds that the Senecio scandens extract inhibits calcium ion internal flow by blocking at least one of an LVDCC ion channel or an NSCCs ion channel so as to relax preshrunk airway smooth muscles.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES

Trachea cannula

A trachea cannula comprises a cannula body (1) and an inflatable bag (2), the cannula body is hollow structured and comprises a front end inserted into oral cavity of human and a rear end outside the oral cavity, and the front end of the cannula body is configured with an opening (6) which is disposed at a head of the front end. The trachea cannula further comprises a visible light source (3), a switch (5) for controlling the visible light source, and a battery (6) supplying power to the visible light source, and both the inflatable bag and the visible light source are secured at the front end of the cannula body; the switch, the battery and the visible light source are connected together in series via wires, forming a closed circuit; the distance from the visible light source to the opening is equal to the distance from a middle point between the third tracheal ring and the fourth tracheal ring to a position 1.5 to 2 cm from tracheal bifurcation at the trachea. Such intubation for the tracheal facilitates the medical staff to determine whether the trachea cannula is located at a correct position conveniently and quickly based on whether the visible light source is placed a position between the third tracheal ring and the fourth tracheal ring, without any harm to human body.
Owner:HUANG ZHIHUI

Application of thickleaf croton root ethanol extract to preparation of medicine for relaxing preshrunk tracheal smooth muscle

The invention relates to the technical field of medicines, in particular to an application of a thickleaf croton root ethanol extract to preparation of a medicine for relaxing preshrunk tracheal smooth muscle. According to the invention, test on in-vitro tracheal ring muscle tension of an experimental mouse discovers that the thickleaf croton root ethanol extract has the effective effect for relaxing tracheal smooth muscle, and the thickleaf croton root ethanol extract is expected to be used for relieving asthma. A basis is provided for developing the application of the thickleaf croton root ethanol extract to preparation of the medicine for relaxing preshrunk tracheal smooth muscle.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES

Application of rauvolfia verticillate ethanol extract to preparation of medicine for relaxing preshrunk tracheal smooth muscle

ActiveCN112755058AEfficient relaxation of tracheal smooth muscleAsthma reliefRespiratory disorderPlant ingredientsLaboratory mousePharmaceutical Substances
The invention relates to the technical field of medicines, in particular to an application of a rauvolfia verticillate ethanol extract to preparation of a medicine for relaxing preshrunk tracheal smooth muscle. According to the invention, test on the in-vitro tracheal ring muscle tension of an experimental mouse discovers that the rauvolfia verticillate ethanol extract has efficient effect of relaxing tracheal smooth muscle, and the substance is expected to be used for relieving asthma. A basis is provided for developing the application of the rauvolfia verticillate ethanol extract to preparation of the medicine for relaxing the preshrunk tracheal smooth muscle.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products