The invention discloses a solid-liquid coupling physical similarity simulation experiment material. The solid-liquid coupling physical similarity simulation experiment material is mainly prepared fromthe following raw materials according to parts by weight: 100 parts of river sand, 8-10 parts of cement, 2-4 parts of talc powders, 2-4 parts of starch, and 2-4 parts of liquid paraffin. The invention further discloses a preparation method of the solid-liquid coupled physical analog simulation experiment material. The solid-liquid coupling physical similarity simulation experiment material disclosed by the invention has the advantages of extensive sources of the raw materials, low cost, environmental friendliness, nontoxicity, high convenience in manufacturing, high easiness in forming, quicksolidification, stable mechanical performances, high fragility and high hydrophobicity; and the proportioning ratio of the material can be adjusted to change the mechanical properties and the water-physical properties of the material, so that the properties of large-scale rocks can be simulated, the solid mechanical properties and the permeability can be simultaneously simulated, and the simulation similarity is high.