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30 results about "Polyethylene glycol electrolyte" patented technology

Compound polyethylene glycol electrolyte granule and preparation method thereof

The invention discloses a compound polyethylene glycol electrolyte granule and a preparation method thereof. The compound polyethylene glycol electrolyte granule contains polyethylene glycol with an average molecular weight of 3400-4400 and an electrolyte inorganic salt, wherein the D90 particle size of the electrolyte granule is 40-80 meshes. The compound polyethylene glycol electrolyte granule is prepared by the following steps: mixing polyethylene glycol with an average molecular weight of 3400-4400 and the electrolyte inorganic salt, performing melting granulation by adopting a hot melt extruder, wherein the melting granulation temperature is 40-80 DEG C, and the screw speed is 60-140rpm; and then performing granulating by adopting a screen with a pore diameter of 0.40-4.00mm, and wrapping or packaging the granules in a packaging container in a unit dose mode to form a compound polyethylene glycol electrolyte granule product. Quality of the compound polyethylene glycol electrolytegranule provided by the invention is controllable, the problem of secondary layering in a production and preparation process of polyethylene glycol electrolyte powder is solved, and the production process is simple. The adopted melting granulation process is a continuous production process, so that production efficiency is improved, productivity is increased, and cost is reduced.
Owner:BEIJING MEDISAN TECH +1

Compound polyethylene glycol electrolyte composition

The invention discloses a compound polyethylene glycol electrolyte composition, which comprises the following components in parts by weight: 1 part of polyethylene glycol (4000), 0.01-0.05 part of potassium chloride, 0.03-0.06 part of sodium bicarbonate, 0.02-0.06 part of sodium chloride, and 0.9-1.2 parts of anhydrous sodium sulphate. The dosage form of the compound polyethylene glycol electrolyte composition disclosed by the invention is powder. The preparation method of the compound polyethylene glycol electrolyte composition comprises the following steps of respectively crushing polyethylene glycol 4000, potassium chloride, sodium bicarbonate, sodium chloride and anhydrous sodium sulphate, sieving through a 100-mesh sieve, and drying; weighing potassium chloride and sodium bicarbonate fine powder in prescription amount, uniformly mixing, and carrying out split charging in a packet A; weighing anhydrous sodium sulphate and sodium chloride fine powder in prescription amount, uniformly mixing, and split charging in a packet B; weighing polyethylene glycol 4000 fine powder in prescription amount, and split charging in a packet C; putting spared materials into a mixer to mix, and sampling to detect the content of a midbody; and carrying out split charging after calculating and loading according to the content of the midbody, thereby obtaining the compound polyethylene glycol electrolyte composition after sealing.
Owner:YANGTZE RIVER PHARM GRP GUANGZHOU HAIRUI PHARM CO LTD

Compound polyethylene glycol electrolyte and preparation method thereof

PendingCN114366757AOvercoming Difficulties of Inhomogeneous MixingFix storage stability issuesPowder deliveryDigestive systemPolythylene glycolPhysical chemistry
The invention discloses a compound polyethylene glycol electrolyte composition. The compound polyethylene glycol electrolyte composition is prepared from the following components in parts by mass: 1 part of polyethylene glycol (4000), 0.01 to 0.05 part of potassium chloride, 0.02 to 0.05 part of sodium bicarbonate, 0.02 to 0.05 part of sodium chloride, 0.07 to 1.0 part of anhydrous sodium sulfate and 0.001 to 0.01 part of saccharin sodium salt. The preparation method of the compound polyethylene glycol electrolyte composition comprises the following steps: (1) respectively crushing or screening sodium bicarbonate, anhydrous sodium sulfate, potassium chloride, sodium chloride and saccharin sodium salt; (2) weighing sodium bicarbonate, anhydrous sodium sulfate, potassium chloride, sodium chloride and saccharin sodium according to the prescription amount, and mixing in a wet granulation mixer; (3) weighing the polyethylene glycol 4000 and the premixed powder according to the prescription amount, mixing the polyethylene glycol 4000 and the premixed powder in a hopper type mixer, sampling and detecting the content of an intermediate; and (4) sub-packaging: calculating the packaging amount according to the content of the intermediate, and sub-packaging by adopting a composite membrane.
Owner:重庆健能医药开发有限公司

Polyethylene glycol-electrolyte oral solution

The invention provides polyethylene glycol-electrolyte oral solution, which comprises 59 to 60 grams of polyethylene glycol, 1.0 to 1.5 grams of sodium chloride, 0.5 to 1.0 gram of potassium chloride, 1.5 to 2.0 grams of sodium bicarbonate, 5.5 to 6.0 grams of sodium sulfate, 0.02 to 0.5 gram of edentate, 0.02 to0.5 gram of sweetener, 1 to 2 milliliters of flavoring essence and the balance of deionized water, wherein the solution is 1,000 milliliters. The polyethylene glycol-electrolyte oral solution is used in bowel cleansing and has the characteristics of quick response, safety, reliability and good cleansing effect. The oral solution is mainly suitable for cleansing bowels before colonoscopy, barium enema X-ray examination and gastrointestinal operation. The small-dose (about one eighth of a bowel cleansing dose) products of the oral solution can be used for treating chronic constipation.
Owner:BEIJING SHENGYONG PHARMA

Method for detecting content of sodium, potassium and chloride ions in polyethylene glycol electrolyte preparation

The invention belongs to the field of medicine, and particularly provides a method for detecting the content of sodium, potassium and chloride ions in a polyethylene glycol electrolyte preparation by using a high performance liquid chromatography method. According to the specific chromatographic condition, the leacheate of cation sodium and potassium is an aqueous solution of 2.3-2.7mM nitric acid, having a flowing speed of 0.8-1.2ml / min; and the leacheate of anion chloride is an aqueous solution of 3.2-3.8mM sodium carbonate and 0.9-1.1mM sodium bicarbonate, having a flow speed of 0.6-0.8ml / min; the chromatographic column is an ion-exchange chromatographic column; and the detector is an electrical conductivity detector. The detecting method has the advantages of strong specificity, simple and quick operation, high sensitivity, relatively good repeatability, relatively good precision and the like.
Owner:STAIDSON BEIJING BIOPHARMACEUTICALS CO LTD +1

Method for determining total sodium content in compound polyethylene glycol electrolyte powder

The invention discloses a method for measuring the total sodium content in compound polyethylene glycol electrolyte powder. The method comprises the following steps: (1) preparing a reference substance solution, namely preparing the reference substance solution with the sodium element concentration of 14.33494 mg / L; (2) preparing a standard solution: precisely measuring the reference solution to prepare a sodium element series standard solution; (3) preparation of a test solution: taking the content of the compound polyethylene glycol electrolyte powder, and preparing the content with the concentration matched with the sodium element series standard solution; (4) preparation of a blank solution: precisely weighing a proper amount of polyethylene glycol, and preparing a solution with a concentration matched with that of the test solution; and (5) respectively taking the blank solution, the standard solution and the test solution, measuring absorbance at the wavelength of 589.0 nm, drawing a regression equation according to the concentration of the standard solution and the absorbance, and calculating the concentration of sodium in the test solution. The method disclosed by the invention is simple and rapid to operate, high in sensitivity and good in repeatability, the solution stability in the method is good, and the measured data is more accurate.
Owner:上海耀大生物科技有限公司

MHR stepped immunity recombination therapy

InactiveCN105617518AMinimally invasive and painless treatmentThe whole treatment is safe and reliableGastroscopesOesophagoscopesSide effectMedicine
The invention discloses an MHR stepped immunity recombination therapy, comprising the following steps: orally taking 4000 ML of compound polyethylene glycol electrolyte powder the day before treatment until clear stool is present in defecation and contains little solid; subjecting a focus to fine examination, diagnosis and typing by an imported digital ultrasonic electronic gastroscopic device; targeting and focusing ulcers under acute and fine high-definition images to subject enteric cavity ulcers, erosion area and distribution to targeted spot injection repairing, and precisely repairing at ulcer mucous layers, from spot to area.The therapy of the invention is a safe and effective green therapy with no side effect.
Owner:BEIJING ZHONGSHAN HOSPITAL CO LTD

Method for detecting pelvic organs by ultrasound intracavitary probe after filling of transrectal enteric cavity

The invention discloses a method for detecting pelvic organs by an ultrasound intracavitary probe after filling of a transrectal enteric cavity contrast agent, and belongs to the technical field of medical uses. The method comprises the following steps: 1, giving an oral dose of compound polyethylene glycol electrolyte powder for a patient; 2, preparing an ultrasound contrast agent; 3, carrying out a colorectal ultrasound contrast examination. The method disclosed by the invention has the advantages of easy and simple operation, safety and capability of being repeatedly examined, meets requirements of noninvasive diagnosis and treatment, is more easily accepted by the patient, and further conducive to the early diagnosis of pelvic diseases and targeted therapies of local regions, thereby being specially suitable for the examinations of unmarried adult women; the method enables the pelvic organs to be visualized and standardized, and improves the scientificity, furthermore, the transrectal enteric cavity contrast agent of the invention has the advantages of being a gastric filling contrast agent for oral use, non-toxic and harmless to a human body, reasonable in design, safer and more effective in use and suitable for the early diagnosis of the pelvic diseases, differential diagnosis and the diagnosis and treatment of the targeted therapies of the local regions, thereby having stronger market popularization values.
Owner:SHAOXING UNIVERSITY

Method for determining content of potassium chloride in compound polyethylene glycol electrolyte powder

The invention discloses a method for determining the content of potassium chloride in compound polyethylene glycol electrolyte powder. The method comprises the following steps: (1) preparing a reference substance solution: preparing a reference substance solution of potassium element; (2) preparing a standard solution: precisely measuring the reference solution to prepare a sodium element series standard solution; (3) preparing a test solution: taking the content of the compound polyethylene glycol electrolyte powder, and preparing a concentration matched with the potassium element series standard solution; (4) preparing a blank solution: precisely weighing a proper amount of polyethylene glycol, and preparing a solution with a concentration matched with that of the test solution; and (5) respectively taking the blank solution, the standard solution and the test solution, measuring absorbance at the wavelength of 766.5 nm, drawing a regression equation according to the concentration of the standard solution and the absorbance, and calculating the concentration of potassium chloride in the test solution. The method disclosed by the invention is simple and rapid to operate, high in sensitivity and high in repeatability, the solution stability in the method is good, and the measured data is more accurate.
Owner:上海耀大生物科技有限公司 +1
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