Electrolyte powder containing polyethylene glycol and preparation method of electrolyte powder

A polyethylene glycol and electrolyte technology, applied in the field of medicine, can solve the problems of cumbersome manufacturing process, troublesome use by patients and high manufacturing cost, and achieve the effects of easy implementation, high production efficiency and low cost

Active Publication Date: 2020-09-04
南京金凯木纳米材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The above-mentioned sub-packaging causes cumbersome manufacturing process, high production cost, waste of resources and other problems, and will also bring certain troubles to the use of patients

Method used

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  • Electrolyte powder containing polyethylene glycol and preparation method of electrolyte powder
  • Electrolyte powder containing polyethylene glycol and preparation method of electrolyte powder

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preparation example Construction

[0030] According to the method for preparing polyethylene glycol-containing electrolyte powder of the present invention, the method may further comprise the steps:

[0031] (1) Grinding, sieving, and drying polyethylene glycol, polylactic acid, inorganic salts and additives respectively; among them, the D97 particle size of polyethylene glycol after sieving is 160-200 μm, and the D97 particle size of polylactic acid The D97 particle size of inorganic salts is 120-160 μm, and the D97 particle size of additives is 80-120 μm; (2) Weigh the prescription amount of polyethylene glycol, polylactic acid, inorganic salts and additives , for standby; (3) Put the above-mentioned spare materials into a mixer and mix for 30-60 minutes, and take a sample to detect the content of intermediates; (4) Calculate the filling amount according to the intermediate content, divide it into packages, and seal it to get it.

[0032] According to the present invention, D97 refers to the corresponding par...

Embodiment 1

[0035]Take by weighing 75000g polyethylene glycol (4000), 15000g polylactic acid, 350g sodium chloride, 350g potassium chloride, 2000g gelatin, 200g cyclamate and 300g lemon essence, through pulverizing, sieving, make its D97 particle diameter reach requirement, After drying at 40°C for 1 h, it was ready for use. Put the above spare materials in a mixer and mix for 30 minutes, then take a sample to test the content of the intermediates. After passing the test, calculate the filling amount according to the intermediate content, divide them into plastic bottles with scales, add stoppers, and press the caps to seal. Among them, each bag contains polyethylene glycol (4000) 75g, polylactic acid 15g, sodium chloride 0.35g, potassium chloride 0.35g, gelatin 2g, cyclamate 0.2g and lemon essence 0.3g.

Embodiment 2

[0037] Weigh 75000g polyethylene glycol (4000), 10000g polylactic acid, 350g sodium chloride, 350g potassium chloride, 200g sodium bicarbonate, 3000g gelatin, 300g saccharin sodium and 300g lemon essence, crush and sieve to make it D97 When the particle size reaches the requirement, dry it at 50°C for 1 hour, and then use it for later use. Put the above spare materials in the mixer and mix them for 40 minutes, then take a sample to test the content of the intermediates. After passing the test, calculate the filling amount according to the intermediate content, divide them into plastic bottles with scales, add stoppers, and press the caps to seal. Among them, each bag contains 75g of polyethylene glycol (4000), 10g of polylactic acid, 0.35g of sodium chloride, 0.35g of potassium chloride, 0.2g of sodium bicarbonate, 3g of gelatin, 0.3g of sodium saccharin and 0.3g of lemon essence.

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Abstract

The invention discloses electrolyte powder containing polyethylene glycol. The electrolyte powder contains polyethylene glycol, polylactic acid, inorganic salts and auxiliaries, and the electrolyte powder comprises components in percentage by weight as follows: 70%-80% of polyethylene glycol, 10%-20% of polylactic acid, 0.5%-1% of inorganic salts and 1%-3% of the auxiliaries. The invention furtherdiscloses a preparation method of the electrolyte powder containing polyethylene glycol. The electrolyte powder containing polyethylene glycol has a good effect, has few adverse reactions and is suitable for being used by patients. Besides, the preparation method is simple, the raw materials are easily available, and the cost is relatively low.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an electrolyte powder containing polyethylene glycol and a preparation method thereof. Background technique [0002] Polyethylene Glycol (PEG) is a long-chain polymer polymerized by ethylene oxide. If the relative molecular weight exceeds 3000, it cannot be absorbed in the intestine, and there is a lack of degradation of PEG in the intestine. Polyethylene glycol (PEG) 4000 enzymes have the effect of laxative and bowel cleansing. Clinically commonly used polyethylene glycols include polyethylene glycol 4000 and 3350. Its mechanism of action is that after it enters the body orally, it can form hydrogen bonds with water molecules to keep the water in the colon, increase the water content of the feces and soften the feces, restore the volume and weight of the feces to normal, and promote the final completion of defecation, thereby improving Constipation symptoms; in add...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/14A61K9/14A61K47/34A61P1/10A61K31/765A61K33/00A61K33/04
CPCA61K33/14A61K33/04A61K33/00A61K31/765A61K9/146A61P1/10A61K2300/00Y02E60/10
Inventor 李颖杨锋程彦丰杨静宋晓萍
Owner 南京金凯木纳米材料有限公司
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