Compound polyethylene glycol electrolyte powder and preparation method thereof

Abstract

The invention provides a compound polyethylene glycol electrolyte powder and a preparation method thereof. The compound polyethylene glycol electrolyte powder comprises 1 part of polyethylene glycol 4000, 0.05-0.12 part of anhydrous sodium sulfate, 0.01-0.05 part of sodium bicarbonate, 0.01-0.06 part of sodium chloride, and 0.007-0.028 part of potassium chloride. The preparation method of the compound polyethylene glycol electrolyte powder is as follows: respectively crushing and sieving anhydrous sodium sulfate, sodium bicarbonate, sodium chloride, and potassium chloride; then weighing a prescription amount of polyethylene glycol 4000, anhydrous sodium sulfate, sodium bicarbonate, sodium chloride, and potassium chloride for standby application; putting the above-mentioned materials for standby application into a mixer for mixing, performing sampling and testing an intermediate content; and calculating a filling amount based on the intermediate content, performing sub-packing, and performing sealing to obtain the compound polyethylene glycol electrolyte powder.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a compound polyethylene glycol electrolyte powder and a preparation method thereof. Background technique [0002] The purpose of preoperative bowel preparation is to assist patients to expel accumulated feces and gas, empty the intestinal tract, reduce intraoperative flatulence, facilitate the exposure of the surgical field of view, and avoid stool contamination of the operating table due to anesthetic relaxation of the anal sphincter during surgery. An ideal bowel preparation drug needs to meet the requirements of clean bowel without feces, reduce irritation and damage to the lesion, avoid intestinal wall edema, reduce pain of patients, and be easy for patients to accept. According to the mechanism of action, the commonly used drugs for intestinal cleansing can be divided into stimulant laxatives, bulky laxatives, lubricating laxatives and osmotic laxatives. Osmoti...

AI Technical Summary

Problems solved by technology

The problems brought by such multi-package powders are (1) the production process is cumbersome, energy-consuming, and not environmentally friendly; (2) due to the large number of packages, the loading capacity is uneven, the quality is uncontrollable, and the yield is low; Too many bags are troublesome to use and easy to cause waste; (5) when the powder is prepared into a solution, the concentration is inaccurate, and the osmotic pressure ratio of the solution cannot be guaranteed to be 1, which affects the cleaning effect

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