177 results about "Gastroduodenal ulcer" patented technology

Live strains of Lactococcus sp. HY 49, Lactobacillus casei HY 2782, and Bifidobacterium longum HY 8001 maintained in nutritious foods, such as yogurt, imbue them with prophylactic and / or therapeutic properties. Such foods are beneficial in the prevention and / or treatment of gastritis, duodenal and gastric ulcers caused by infection from Helicobacter pylori (also referred to as H. pylori). The properties of these bacteria are boosted by the addition of egg yolk containing antibodies specific to H. pylori antigen derived from "fractionated H. pylori".

A Chinese medicine for treating gastritis, acute or chronic gastritis, duodenal bulbar inflammation, gastric ulcer, duodenal ulcer, etc is prepared from 16 Chinese-medicinal materials including dandelion herb, lily bulb, white peony root, tangerine peel, etc. Its preparing process is also disclosed.

The invention relates to the technical field of a traditional Chinese medicine, and discloses a traditional Chinese medicine for treating chronic gastritis and gastroduodenal ulcer, which is prepared from the raw material medicines by weight: 12g of cortex magnoliae officinalis, 12g of pericarpium citri reticulatae, 12g of angelica sinensis, 12g of radix paeoniae alba, 10g of radix aucklandiae, 10g of radix burpleuri, 30g of cuttlebone, 10g of pinellia ternate, 10g of fructus evodiae, 6g of rhizoma coptidis, 6g of fructus amomi, 12g of poria cocos, 10g of rhizoma atractylodis, 20g of traxacum mongolicum, 10g of fructus aurantii, 10g of radix glycyrrhizae preparata and 20g of hemerocallis miner. According to the traditional Chinese medicine, the traditional Chinese medicine is convenient to take, easy to absorb, takes effect instantly, and is good in curative effect and low in price. The effective ratio reaches up to 96.77% by observing the treatment of 186 patients via the clinical application.

The invention discloses a Chinese medicinal preparation for treating duodenal ulcer, which comprises the following Chinese herbal medicines in part by weight: 10 to 20 parts of astragalus, 10 to 20 parts of peach seed, 10 to 20 parts of bletilla, 10 to 20 parts of nutgrass galingale rhizome, 10 to 20 parts of white paeony root, 10 to 20 parts of largehead atractylodes rhizome, 10 to 20 parts of Indian buead, 10 to 20 parts of honey-fired liquoric root, 10 to 20 parts of emblic leafflower fruit, 10 to 20 parts of Chinese gall, 10 to 20 parts of combined spicebush root, 10 to 20 parts of tangerine peel, 10 to 20 parts of chicken's gizzard-membrane, 10 to 20 parts of notoginseng root, 10 to 20 parts of bupleurum, 10 to 20 parts of sanguisorba root, 10 to 20 parts of ginger, 10 to 20 parts of rosewood heart wood, 10 to 20 parts of root of red-rooted salvia, 10 to 20 parts of cuttlefish bone and 10 to 20 parts of cinnamomvine. The Chinese medicinal preparation has the effects of calming liver and regulating flow of qi, tonifying spleen, lung and kidney, tonifying middle-Jiao and qi and stopping bleeding and preventing or arresting vomiting, is mainly used for treating discomfort in spleen and stomach and weakness of the spleen and the stomach, and fulfills the aims of stopping diarrhea and diminishing inflammation, relieving spasm and pain, improving local blood circulation and metabolism, enhancing the immunologic function of intestinal tracts and promoting ulcer healing. The Chinese medicinal preparation has a simple preparation process, small toxic or side effects and low cost, and is convenient to administrate and easy to prepare.

An object of the present invention is to provide an agent for treating or preventing digestive ulcer that is effective even to ulcer of small intestine and others, for which gastric acid secretion inhibitors such as proton pump inhibitors are ineffective, and is superior to allopurinol in the efficaciousness and the safety.The pharmaceutical composition of the present invention comprising a non-purine xanthine oxidase inhibitor as the active ingredient is useful as an agent for treating or preventing ulcer that forms in digestive tracts by the attack of gastric acid, pepsin, stress, Helicobacter pylori bacteria, NSAID, etc. In particular, it is useful as an ulcer remedy heretofore unknown in the art as it is effective even for ulcer in small intestine for which gastric / duodenal ulcer remedies that inhibit gastric acid secretion such as proton pump inhibitors are ineffective.

The invention relates to Chinese medicinal compositions for treating gastric ulcer, duodenal ulcer and process for preparation, which is prepared from corydalis tuber, banksia rose, evodia rutaecarpa, dried ginger, dried orange peel, cyperus tuber, toosendan fruit, root of herbaceous peony, honey-fried licorice root, blood clam shell, rice sprout and germinated barley. The dose forms of the medicament include granules, hard capsules, soft capsules, tablets, dripping pills, pills and oral liquid preparations.

The invention relates to a traditional Chinese medicine combination for curing gastric diseases and a preparation method thereof, which solve the problem that the original traditional Chinese combinations for curing gastric diseases do not have prominent effects and have high recurrence rate. The medicine combination is prepared by corydalis tuber, Chinaberry fruit, turmeric root tuber, evodia rutaecarpa, coptis chinensis, villous amomum fruit, costus root, radix linderae, rhizoma cyperi, frankincense, myrrh and cuttlebone. The traditional Chinese medicine combination has the functions of soothing the liver and regulating vital energy, removing heat from the liver, promoting blood circulation to arrest pain, promoting wound healing and granulation, and can be used for curing gastric and duodenal ulcer, gastritis, stomachache, salivation and sour regurgitation, nausea, retching, epigastric distension and depression; besides, the traditional Chinese combination has special curative effects on gastric ulcer and duodenal ulcer and has inhibiting effect on helicobacter pylori.

The objective of the invention is to provide a medicinal and edible composition having no toxic or side effect and especially a composition capable of replenishing qi, invigorating the spleen and nourishing the stomach. The composition is prepared from the following ingredients: ginseng roots, poria cocos, Chinese yam, lotus seeds, coix seeds, white hyacinth beans and wheat flour. One or a plurality of the following substances also can be added into the traditional Chinese medicinal composition: tangerine peel, perilla, fructus amomi, prepared licorice roots, bighead atractylodes rhizomes, platycodon roots, jujubes, sesame, ginseng leaves, haws, chicken gizzard-membrane, malt, hyacinth-bean flowers and semen raphani. The invention also relates to the application of the composition containing the ingredients by a certain weight ratio in preparing health care food or medicines or products having functions of preventing and treating chronic gastritis, peptic ulcer, chronic diarrhea, functional dyspepsia, ulcerative colitis and syndrome of weakness of the spleen and the stomach, replenishing qi, invigorating the spleen, nourishing the stomach and relieving abdominal distension and pain and loss of appetite caused by the chronic gastritis, gastroduodenal ulcer, the chronic diarrhea, the functional dyspepsia and the ulcerative colitis.

The invention discloses a medicine combination used for treating coronary heart disease angina and epigastric pain and a preparation method thereof; the medicine combination is mainly made from snakegourd fruit, salvia, bulbus allii macrostemi, pinellia ternata, rhizoma corydalis, tangerine peel, citrus aurantium, cassia twig, villous amomum fruit and sandalwood. The medicine combination of the invention has the function of activating Yang and eliminating phlegm, and promoting blood circulation and relieving congestion and is mainly indicated for chest distress of phlegm obstruction and blood stasis, angina pectoris and stomachache; the medicine combination can also be used for treating chronic gastritis, gastroduodenal ulcer, stomach neurosis, chronic hepatitis, and chronic pancreatitis. The medicine combination of the invention is characterized by simple prescription, convenient production, convenient administration for patients and remarkable curative effects, thus presenting a wide application value.

The present invention relates to novel thiourea derivatives as a modulator for vanilloid receptor (VR) and the pharmaceutical compositions containing the same. As diseases associated with the activity of vanilloid receptor, pain acute pain, chronic pain, neuropathic pain, post-operative pain, migraine, arthralgia, neuropathies, nerve injury, diabetic neuropathy, neurodegeneration, neurotic skin disorder, stroke, urinary bladder hypersensitiveness, irritable bowel syndrome, a respiratory disorder such as asthma or chronic obstructive pulmonary disease, irritation of skin, eye or mucous membrane, fervescence, stomach-duodenal ulcer, inflammatory bowel disease and inflammatory diseases can be enumerated. The present invention provides a pharmaceutical composition for prevention or treatment of these diseases.

The present invention generally relates to pharmaceutical unit dosage forms of NSAIDs and H2-receptor antagonists, in which the H2-receptor antagonist is formulated so as to be released in a sustained manner over a predetermined period of time so as to maintain gastric pH above a desired level for a duration of time. The NSAID may then be formulated for immediate release. The pharmaceutical unit dosage forms may be administered to subjects susceptible to the development of NSAID induced gastric and / or duodenal ulcers, as the sustained release H2-receptor antagonist is formulated so as to maintain the gastric environment above the pH levels where NSAID-induced ulceration typically occurs.

The present invention discloses a compound belladonna bismuth-magnesium tablet and its preparation method. It is made from Chinese medicinal materials of rhubarb, tangerine peel, licorice, saussurea root and acorus root and magnesium trisilicate, bismuth subnitrate and sodium hydrogen carbonate are used as main raw material, and adding starch slurry and microcrystal cellulose, etc. as auxiliary material through a certain preparation process. Said invention compound has the functions of clearing heat away and removing toxic material, promoting circulation of qi, stopping pain, fortifying the spleen, dispersing food, etc. and can be used for curing gastroduodenal ulcer and chronic gastritis, etc.

The invention discloses Chinese medicinal granules for treating gastric ulcer and duodenal ulcer. The Chinese medicinal granules consists of the following Chinese medicines in part by weight: 190 to 210 parts of asystasiella, 140 to 160 parts of beauty-berry leaf, 90 to 110 parts of puff-ball, 140 to 160 parts of hairyvein agrimonia herb and bud, 140 to 160 parts of common cephalanoplos herb and 110 to 130 parts of bletilla. The Chinese medicinal granules can treat the gastric ulcer, the duodenal ulcer and accompanied gastrorrhagia, has the effects of resisting bacteria, diminishing inflammation, clearing heat, detoxicating, astringing to arrest bleeding, relieving swelling and pain, eliminating stasis, killing parasites and protecting and repairing gastric mucosa, is convenient to use, low in cost and efficient and does not have side effect, and gastric ulcer and duodenal ulcer are difficult to relapse after healing.

Yunnan Hongyao tablet is prepared with Yunnan Hongyao 210-283 (in weight portions, the same below), avicel 5-8, cane sugar powder 18-30, dextrin 12-15, magnesium stearate 3, talcum powder 3, CMC in 60 % and alcohol in proper amount. Where, Yunnan Hongyao consists of ten kinds of Chinese medicinal materials, including notoginseng, Chinese paris rhizome, dactylicapnos root, falcate dolichos root or leaf, tuniclike psammosilene root, etc. Yunnan Hongyao tablet is safe, non-toxic, strong in pharmacological effect and wide in indications, and may be used widely in preparing medicines for preventing and treating gastroduodenal ulcer, upper respiratory tract hemorrhage and functional metrorrhagia, stopping pain and resisting rheumatism.

The invention discloses a Chinese medicine preparation for treating gastroduodenal ulcer. The Chinese medicine preparation for treating the gastroduodenal ulcer comprises the following crude drugs: 5 to 15 grams of Atpinia officnarum hange, 5 to 15 grams of Cyperus rotundus, 5 to 15 grams of caulis perllae, 3 to 6 grams of dried orange peel, 3 to 6 grams of finger citron, 5 to 15 grams of citron, 5 to 15 grams of toosendan fruit, 3 to 6 grams of Corydalis tuber, 5 to 15 grams of blood clam shells and 5 to 15 grams of cuttlefish bones. The Chinese medicine preparation for treating the gastroduodenal ulcer has the efficacies of activating qi and relieving pain, warming mid-energizer and stomach, stopping bleeding and absorbing clots, and warming meridian and promoting blood circulation, quickly takes effect and has low cost and no side effect on the body.

The invention relates to a medicament for treating gastric ulcer and duodenal ulcer, which is prepared from the following medicinal herbs (by weight ratio) as raw material: dragon's blood resin 18-30 parts, rhizoma corydalis 5-10 parts, atractylodes rhizome 5-10 parts, licorice root 5-10 parts, blood clam shell 10-20 parts, cyprus longus 5-30 parts, dried orange peel 5-18 parts, cuttle-bone 10-50 parts.

Disclosed is a gastropathy-treating medicine and its preparation, wherein the raw materials include (by weight ratio) bletilla tuber 60-70, astragalus root 60-70, Os Sepiae 60-70, nutgrass flatsedge rhizome 60-70, root of herbaceous peony 60-70, notoginseng 60-70, frankincense 30-40, myrrh 10-20, plant soot 20-30, chicken's gizzard-skin 30-43 and eggshell 0.5-2.

The invention relates to a traditional Chinese medicine composition, particularly a Chinese patent medicine for treating chronic gastritis and gastroduodenal ulcer and a preparation method thereof. The traditional Chinese medicine is prepared from the following components in parts by weight: 50-200 parts of Mangnolia officinalis, 150-300 parts of costus root, 50-200 parts of cuttlebone, 50-150 parts of amomum fruit, 50-150 parts of corydalis tuber, 50-150 parts of dried ginger, 100-200 parts of hyacinth bletilla, 50-150 parts of Chinese date and 60-130 parts of licorice root. The Chinese patent medicine for treating chronic gastritis and gastroduodenal ulcer has the functions of regulating the flow of qi, warming the middle-jiao and alleviating pain. The Chinese patent medicine for treating chronic gastritis and gastroduodenal ulcer is mainly used for treating stomach cold and qi stagnation of epigastralgia, including swelling, pain, anorexia, acid regurgitation, irregular excretion, light texture of tongue, thin and white tongue coat, and weak pulses.

A Chinese medicine for treating gastric ulcer, duodenal ulcer and chronic gastritis is prepared from frankincense, peony root, aucklandia root and liquorice root.

The present invention is related to new vanilloid analogues containing resiniferatoxin pharmacophores, pharmaceutical compositions that have such analogues, and their uses as vanilloid receptor agonists and potent analgesics. The present invention provides a pharmaceutical composition for preventing, alleviating or treating pain, acute pain, chronic pain, neuropathic pain, post-operative pain, migraine, arthralgia, neutopathies, nerve injury, diabetic neuropathy, neurodegeneration, neurotic skin disorder, stroke, urinary bladder hypersensitiveness, irritable bowel syndrome, a respiratory disorder such as asthma or chronic obstructive pulmonary disease, irritation of skin, eye or mucous membrane, fervescence, stomach-duodenal ulcer, inflammatory bowel disease, inflammatory disease or urgent urinary incontinence.

The invention discloses a medicine for treating gastric ulcer and duodenal ulcer, which uses raw medicinal materials comprising dandelion, corydalis tuber and sea buckthorn oil or water extractive or organic solvent extractive as active ingredients, and medicinally acceptable accessories are added to prepare the medicine. The invention further provides a preparing method and an application of the medicine. The medicine prescription uses the commonly-used dandelion as the minister so as to treat gastric ulcer and duodenal ulcer, is remarkable in curative effect, can treat both principal and secondary aspects of disease, achieves the effects of clearing heat and harmonizing stomach, relieving hyperacidity and relieving pain and tonifying spleen and is in accordance with the characteristics of traditional Chinese medicine prescriptions.

The present invention provides a Chinese medicine compound for curing gastric and duodenal ulcer, made from the raw materials with weight portions such as yanhusuo, dandelion, nutgrass flastedge, mastic gum, alum and liquorice, and a preparation method of capsule, tablet, pill, granule, powder, dropping pill and oral liquid of the compound. The present invention has the functions of obvious sterilization and bacteriostasis on helicobacter pylori, reduction of gastric juice amount, gastric free acid and total acidity, and pepsin output, as well as pain alleviating and inflammation resisting, so the present invention has the functions of inhibiting stress type, ostium pyloricum deligation, acetic acid and ethanol ulcer, as well as pain alleviating and inflammation resisting. In addition, the present invention can reduce the stimulus factors of chronic gastricism, gastric ulcer and gastratrophia lesions, improve the symptoms of patients with gastric ulcer and play a promoting role in repairing and improving gastric mucosal lesion.

The invention discloses amomum-fingered citron-dandelion tea and a method for making the same. The amomum-fingered citron-dandelion tea consists of the following raw materials in part by weight: 1 to 8 parts of amomum, 1 to 8 parts of fingered citron, 5 to 15 parts of dandelion, 5 to 15 parts of kudzuvine root and 1 to 6 parts of liquorice. The amomum-fingered citron-dandelion tea has the effects of nourishing the spleen and benefiting the stomach, warming the spleen and relieving diarrhea, soothing the liver and harmonizing the stomach, stimulating appetite and digestion, promoting the circulation of qi, clearing dampness, stopping pain, clearing away heat and toxic materials and helping produce saliva and slaking thirst. The amomum-fingered citron-dandelion tea is especially suitable for people who often drink and suffer from chronic enterogastritis, gastroduodenal ulcer, diabetes, arthrolithiasis, fetid oris caused by damp and hot liver and stomach, and the like.

The invention discloses a traditional Chinese medicine composition capable of treating gastritis, gastric ulcer and duodenal ulcer and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 7 to 15 parts of caulis dendrobii, 4 to 9 parts of fructus citri sarcodactylis, 5 to 6 parts of rhizoma cyperi, 10 to 15 parts of endothelium corneum gigeriae galli, 4 to 6 parts of Chinese angelica, 4 to 10 parts of herba taraxaci, 3 to 5 parts of bighead atractylodes rhizome, 4 to 6 parts of radix aucklandiae, 3 to 7 parts of fructus aurantii immaturus, 5 to 12 parts of cuttlefish bone, 4 to 6 parts of liquorice root, 5 to 8 parts of rhizoma bletillae, 4 to 9 parts of fructus jujubae and 8 to 12 parts of pheretima. The traditional Chinese medicine composition has a remarkable curative effect on the gastritis, the gastric ulcer and the duodenal ulcer and the healing effect is obvious and is better than various treatment methods and medicines at present; the traditional Chinese medicine composition is high in safety and has no toxic side effect; the medicine can be used for adjusting chief cells, parietal cells and mucous cells and the cells are maintained in a normal level range and kept balanced; the medicine can be used for treating both principal and secondary aspect of disease; all the drugs are scientifically matched and the mutual coordination effect is sufficiently expressed; the traditional Chinese medicine composition has the effects of converging and engendering flesh, nourishing yin and clearing away heat, enhancing the appetite, treating, nourishing and protecting stomach and has the characteristics of low cost, rapid effect and lasting curative effect.

The invention relates to the technical field of traditional Chinese medicine, and belongs to a traditional Chinese pharmic composition for treating gastropathy, which consists of the materials with the following weight percentage: 1 to 100 portions of radix linderae, 1 to 100 portions of Chinese Fevervine Herb, 1 to 300 portions of Chinese date, 1 to 300 portions of dendrobe, 1 to 300 portions of Jobstears Seed, 1 to 550 portions of Ficus carica, 1 to 550 portions of golden buckwheat rhizone, 1 to 550 portions of Auriculate Swallowwort Root, 500 to 1000 portions of pork tripe, and 400 to 1000 portions of water. The preparation method comprises the following steps: after the radix linderae, the dendrobe, the Chinese Fevervine Herb, the golden buckwheat rhizone, and the Auriculate Swallowwort Root are decocted into liquid, the Chinese date, the Jobstears Seed, and the Ficus carica are added. The obtained mixture is then filled in the cleaned pork tripe and stewed for obtaining the traditional Chinese pharmic composition. The traditional Chinese pharmic composition can be used for treating symptoms such as poor appetite, belching and acid regurgitation, small food intake and loose stool, chronic gastritis, and superficial erosive gastritis caused by retarding of spleen and stomach Qi, and especially has specific effects on treating gastric ulcer and duodenal ulcer.

The present invention is the recipe and preparation process of medicine for treating gastroduodenal ulcer. The medicine is the mixture of two components, the Component A is medicine powder prepared with notoginseng, evodia, white atractylodes rhizome, rhubarb, tritillary bulb and Chinese yam and through mixing and crushing into 80-100 mesh; and the Component B is fine medicine powder prepared with astragalus root, Chinese goldthread, lindera root, white peony root, cuttlebone and amomum fruit and through decoction to extract its effective component, concentration and stoving and other steps. The medicine has high curative effect on gastroduodenal ulcer and no toxic side effect.

The invention provides a traditional Chinese medicine composition capable of effectively treating duodenal ulcer, belonging to the field of traditional Chinese medicines. The traditional Chinese medicine composition for treating duodenal ulcer is characterized by being prepared from the following raw medicines in parts by weight: 10 parts of cattail pollen, 12 parts of hyacinth bletilla, 8 parts of common burreed rhizome, 15 parts of amomum, 20 parts of lily, 15 parts of agilawood, 10 parts of lychee seed, 8 parts of fingered citron, 12 parts of perilla stem, 8 parts of bitter orange, 15 parts of citron, 12 parts of pericarpium arecae, 10 parts of rhizoma nardostachyos, 8 parts of stringy stonecrop, 15 parts of jujube, 12 parts of dandelion, 20 parts of Chinese pulsatilla and 30 parts of honey. The traditional Chinese medicine composition provided by the invention can be used for treating duodenal ulcer by taking natural traditional Chinese medicines as raw materials and utilizing the comprehensive function of the natural traditional Chinese medicines, and has the advantages of no toxic side effect on human bodies, low price and exact treatment effect. Verified by 100 patients clinically, the effective rate is 95.0%.

The present invention is related to a hyaluronic acid composition with a binary mixture of hyaluronic acids having mainly different weight-average molecular weight and then different rheological, scaffold and degradation properties in aqueous solution. The resulted compositions have demonstrated an optimal balance between adhesion, tissue scaffold and treating time to the peptic and duodenal ulcer and bleeding. Thus, the present inventive binary mixture exhibits a quick and lasting effect on the treatment and prevention of duodenal or peptic ulcer and bleeding which is very good thing indeed.

The invention relates to the field of drug formulae, in particular to a traditional Chinese medicine for treating gastric ulcer. The traditional Chinese medicine is characterized by being prepared from the following raw materials in parts by weight: 77-87 parts of oroxylum indicum, 41-51 parts of greek valerian, 25-35 parts of radix ceratostigmae, 33-43 parts of roundleaf dutchmanspipe root, 25-35 parts of semen aesculi, 18-28 parts of fingered citron, 21-31 parts of bulbiferous stonescrop, 19-29 parts of amomum cardamomum, 14-24 parts of allium macrostemon, 20-30 parts of alpinia katsumadai, 13-23 parts of adiantum, 16-26 parts of semen cuscutae, 10-20 parts of dioscorea cirrhosa, 37-47 parts of jasminum grandiflorum, 24-34 parts of polygonum orientale fruit, 26-36 parts of pterocephalus hookeri, 8-18 parts of perfoliote knotweed herb, 6-16 parts of dwarf galangal rhizome and 8-18 parts of raspberries. The raw materials are mixed, soaked with water, decocted and subjected to residue removal to obtain filter liquor. The traditional Chinese medicine has a remarkable treatment effect on epigastric pain, gastric ulcer and duodenal ulcer, can improve the gastric motility and recover normal metabolism of the stomach, is long in action time, short in treatment course, quick-acting, safe and free of toxic and side effects, and can be widely applied to clinical treatment of the gastric ulcer.