55 results about "Endovascular interventions" patented technology

A method for guiding stent deployment during an endovascular procedure includes providing a virtual stent model of a real stent that specifies a length, diameter, shape, and placement of the real stent. The method further includes projecting the virtual stent model onto a 2-dimensional (2D) DSA image of a target lesion, manipulating a stent deployment mechanism to navigate the stent to the target lesion while simultaneously acquiring real-time 2D fluoroscopic images of the stent navigation, and overlaying each fluoroscopic image on the 2D DSA image having the projected virtual stent model image, where the 2D fluoroscopic images are acquired from a C-arm mounted X-ray apparatus, and updating the projection of the virtual stent model onto the fluoroscopic images whenever a new fluoroscopic image is acquired or whenever the C-arm is moved, where the stent is aligned with the virtual stent model by aligning stent end markers with virtual end markers.

A catheter system for removing occlusive materials from a targeted endoluminal site, such as a vascular graft. The catheter system utilizes an electrical source and a controller to deliver sequences of very small electrical discharges between paired electrodes in a fluid-jet arrangement (i) to cause high fluid flow velocities in the catheter's fluid extraction pathway based on Bernoulli's Law of Pressure Differential, (ii) to create a selected level of turbulent fluid flows within the targeted site to remove occlusive material from the vessel walls and to thereafter suction fluids and entrained embolic particles into the extraction pathway, and (iii) to emulsify any embolic particles having a cross-sectional dimension larger than a couple of hundred micrometers to allows passage of the embolic particles through the elongate catheter to the catheter handle.

The invention relates to systems and methods to improve perfusion flow and pressure during endovascular intervention. In particular, the invention relates to catheters that enable both antegrade and retrograde flow through the catheter during a recanalization procedure and specifically at the step in a procedure where a clot is being withdrawn. Additionally, the invention provides systems for supplying fluids and fluid compositions to improve nutrition to ischemic brain.

A catheter system for removing occlusive materials from a targeted endoluminal site, such as a vascular graft. The catheter system utilizes an electrical source and a controller to deliver sequences of very small electrical discharges between paired electrodes in a fluid-jet arrangement (i) to cause high fluid flow velocities in the catheter's fluid extraction pathway based on Bernoulli's Law of Pressure Differential, (ii) to create a selected level of turbulent fluid flows within the targeted site to remove occlusive material from the vessel walls and to thereafter suction fluids and entrained embolic particles into the extraction pathway, and (iii) to emulsify any embolic particles having a cross-sectional dimension larger than a couple of hundred micrometers to allows passage of the embolic particles through the elongate catheter to the catheter handle.

A method (100) of aneurysm analysis (110) and virtual stent simulation (120) for endovascular treatment of sidewall intracranial aneurysms.

Embodiments of the present invention provide a system for simulating the endovascular intervention operation. The system comprises an image acquiring device, a model establishment device, a physical surgical instrument and a display. The image acquiring device is configured to acquire the medical image data of blood vessels, perivascular tissues and perivascular organs that are subjected to the simulation for the endovascular intervention operation, wherein the medical image data are specified for a patient. The model establishment device is configured to establish a three-dimensional geometric model of the blood vessels, the perivascular tissues and the perivascular organs in the medical image data. The physical surgical instrument is operated by a user to simulate the endovascular intervention operation. The model establishment device is also configured to control the motion trajectory of a three-dimensional model of the surgical instrument in the three-dimensional geometric model of the blood vessels according to the operation of the user on the physical surgical instrument. The display is configured to display the three-dimensional geometric model of the blood vessels, the perivascular tissues and the perivascular organs and the motion trajectory of the three-dimensional model of the surgical instrument in the three-dimensional geometric model of the blood vessels. According to the technical scheme of the invention, the operation plan of a patient can be formulated in the personalized manner. Meanwhile, the operation path is optimized and the operation can be rehearsed.

The invention relates to a catheter for endovascular treatment on hypertension, in particular to a medical catheter for clinical endovascular intervention treatment on hypertension. The catheter has the functions of monitoring the temperature of the vascular tissue of the renal artery and measuring the local impedance of the tissue of the renal artery, and is used for carrying out feedback regulation on radio and high frequency current intensity to block bilateral renal sympathetic nerves and interdict sympathetic nerves to excite the kidney to generate and secrete renin-angiotensin, thereby achieving the purpose of reducing blood pressure. The catheter provided by the invention is made by compositing temperature plastic polymers and wire meshes, wherein the hardness of a near end is larger, a far end is softer, and multiple channels are formed in a catheter body; a far-end electrode is made from platinum (or gold) composite materials at the front end of the catheter, and multiple leads and drawing wires of the electrode are connected with a handle and a joint through the channels in the catheter body; and high-efficiency electrical isolation pipes and drawing pipes arranged in the channels of the catheter body ensure electrical signal transmission and smooth traction, thereby finishing bending and stretching operations.

The invention discloses a passive positioning mechanical arm for a propelling mechanism of an endovascular intervention surgical robot. The mechanical arm is mounted on an operating table and comprises a base module, a horizontal moving module, a lifting module, a first rotating joint, a second rotating joint and a pitch angle adjusting module, wherein the base module is mounted on the operating table; the horizontal moving module is mounted on the base module; the bottom of the lifting module is mounted on the horizontal moving module; one end of the first rotating joint is mounted at the topof the lifting module, and the other end of the first rotating joint is connected with one end of the second rotating joint; the pitch angle adjusting module is mounted at the other end of the secondrotating joint; and the surgical robot is mounted on the pitch angle adjusting module. The mechanical arm can freely adjust the horizontal displacement and angle of the surgical robot, the angle of acatheter of the surgical robot entering a blood vessel and the height of the robot in the vertical direction and lock the posture of the surgical robot to prevent shaking during an operation.

Wound closure apparatus is provided having a force-transmitting surface operable to be placed in a proximal, external, wound-closing position on a patient, together with a force-exerting assembly operable to exert a wound-closing pressure against the patient's tissue. The force-transmitting surface is preferably three-dimensionally asymmetric to generate different forces along the length of the surface. The apparatus is especially designed for the closure of wounds attendant to endovascular interventions, e.g., a femoral artery puncture wound. The apparatus is positioned and operated so as to partially close the patient's artery upstream of the arteriotomy. The apparatus and methods hereof may also be used for the closure of wounds created during venous intervention procedures. A smaller wound closure apparatus is provided for the closure of brachial and radial wounds, and has a wrist or arm strap for securing the apparatus onto the wrist or bicep region of a patient.

The invention relates to a hydrophilic lubricating polyurethane medical interventional catheter and a preparation method thereof. The tube body material of the catheter is a melt-mixed material of carboxyl-containing thermoplastic polyurethane elastomer and carboxyl-free thermoplastic polyurethane elastomer. The outer surface of the catheter is coated with A hydrophilic coating that can be covalently bonded to the catheter, the hydrophilic coating includes a bottom coating that can be grafted to the outer surface of the catheter, and a top coating that forms a semi-interpenetrating cross-linked network structure with the bottom coating . The present invention utilizes the chemical bond grafting technology of the catheter and the coating and the semi-interpenetrating network construction technology of the hydrophilic polymer and the coating to effectively combine the catheter and the coating closely, and obtain high lubricity and wear resistance. The polyurethane medical interventional catheter is suitable for use in the field of endovascular interventional diagnosis and treatment.

The invention relates to a hyperbranched polyester-modified polyurethane medical interventional catheter and a manufacturing method thereof. A catheter body of the catheter is made from a mixed fused material of hyperbranched polyester which contains carboxyl groups and palmitate groups in end groups thereof and a thermoplastic polyurethane elastomer, wherein a hydrophilic coating, which is in covalent bond connection to the catheter, is coated on the outer surface of the catheter; and the hydrophilic coating includes a bottom coating, which can be grated with the outer surface of the catheter, and a top coating which forms a semi-interpenetrating network structure with the bottom coating. According to the medical interventional catheter and the manufacturing method thereof disclosed by the invention, on the basis of the property that the hyperbranched polyester has a great amount of the end groups, and in combination with a chemical bond grating technology between the catheter and the coating as well as a semi-interpenetrating network construction technology between a hydrophilic polymer and the coating, the catheter and the coating are closely combined effectively, so that the manufactured polyurethane medical interventional catheter is excellent in lubricating property and abrasion resistance; and the catheter is applicable to the field of endovascular intervention diagnosis and treatment.

An occlusion device for vascular surgery, suitable for clogging treatments of vascular entry sites and for endovascular interventions such as embolizations of blood vessels, treatment of arteriovenous malformations or small aneurysms, arterial dissections and the like, by releasing in an operation region a quick setting surgical glue or haemostatic fluid, through an outlet mouth of a duct. The device prevents the surgical glue from contacting within the duct a patient's biological fluids, in particular blood, which would close the duct. In the case of clogging treatments of vascular entry sites, a backflow preventing device may be provided, preferably provided by a coupling device between the duct and an introducer sheath by which an outlet mouth is kept in contact to keep in a one-way fluid tight contact against the outer surface of the introducer sheath until an injection pressure P2 is applied to cause release of the surgical glue.

Wound closure apparatus is provided including a body having an elongated, lowermost force-transmitting surface operable to be placed in a proximal, external, wound-closing position on a patient, together with a force-exerting assembly coupled with the body and operable to exert a downwardly directed force serving to generate wound-closing pressure against the patient's tissue. The force-transmitting surface is preferably three-dimensionally asymmetric so that forces of different magnitude are exerted at different locations along the length of the surface. The apparatus is especially designed for the closure of wounds attendant to endovascular interventions, e.g., a femoral artery puncture wound incident to percutaneous cardiac intervention (PCI), and is capable of quickly effecting wound closure with a time-to-ambulation (TTA) of approximately 60 minutes, and with a very low complication rate.

Wound closure apparatus is provided including a body having an elongated, lowermost force-transmitting surface operable to be placed in a proximal, external, wound-closing position on a patient, together with a force-exerting assembly coupled with the body and operable to exert a downwardly directed force serving to generate wound-closing pressure against the patient's tissue. The force-transmitting surface is preferably three-dimensionally asymmetric so that forces of different magnitude are exerted at different locations along the length of the surface. The apparatus is especially designed for the closure of wounds attendant to endovascular interventions, e.g., a femoral artery puncture wound incident to percutaneous cardiac intervention (PCI), and is capable of quickly effecting wound closure with a time-to-ambulation (TTA) of approximately 60 minutes, and with a very low complication rate.

A method for guiding stent deployment during an endovascular procedure includes providing a virtual stent model of a real stent that specifies a length, diameter, shape, and placement of the real stent. The method further includes projecting the virtual stent model onto a 2-dimensional (2D) DSA image of a target lesion, manipulating a stent deployment mechanism to navigate the stent to the target lesion while simultaneously acquiring real-time 2D fluoroscopic images of the stent navigation, and overlaying each fluoroscopic image on the 2D DSA image having the projected virtual stent model image, where the 2D fluoroscopic images are acquired from a C-arm mounted X-ray apparatus, and updating the projection of the virtual stent model onto the fluoroscopic images whenever a new fluoroscopic image is acquired or whenever the C-arm is moved, where the stent is aligned with the virtual stent model by aligning stent end markers with virtual end markers.

The invention disclosed herein provides endovascular intervention methods that entail creating a temporary capillary block in the vasculature of at least a portion of a patient's organ, such as a hemisphere of the patient's brain, the capillary block essentially blocking blood flow through capillaries in the portion of the patient's organ, and performing the endovascular intervention. Distal embolism protection devices are also disclosed that include a blood pump and at least one of a centrifuge element, a dialysis element, a cooling element, and a filtration element. The blood pump is generally capable of drawing blood from a patient's vein, circulating the blood through each of the elements so that a characteristic of a blood component may be manipulated therewith, and perfusing the modified blood into a patient's artery. A capillary block is thereby created in the vasculature of at least a portion of a patient's organ with manipulated blood components.

The invention relates to an endovascular intervention stent. The endovascular intervention stent comprises a plurality of annular bodies and a plurality of connecting parts, wherein the connecting parts are used for connecting the annular bodies; each annular body is provided with a plurality of crossing rib beams which are uniformly distributed along the corresponding annular bodya ring; each connecting part is provided with a V-shaped connecting rod; a square buckle is arranged at the end part of each connecting rod and is used for connecting the corresponding annular body; coating layers are coatedat the connecting parts and the annular bodies are coatedwithcoating layers. The endovascular intervention stent has the advantages that by adopting the splitting structure of the connecting parts and the annular bodies, the support property of the stent is guaranteed, the smoothness with blood vessels is also guaranteed, and the length is conveniently adjusted according to requirements; the annular bodies are made of titanium alloy, so that the strength requirement is met; the connecting parts are made of copper-based alloy, so that the certain elasticity and toughness are realized, and the shape stability is guaranteed.

The invention provides an endovascular intervention robot and an endovascular intervention system. The endovascular intervention robot comprises a base, a disc-shaped catheter bank, a catheter guide mechanism, a catheter conveying mechanism and a guide wire conveying mechanism, wherein the disc-shaped catheter bank is rotationally arranged on the base and is used for winding and storing a catheter; the catheter conveying mechanism is arranged on the base and is relatively positioned at the remote end of the disc-shaped catheter bank; the catheter conveying mechanism is used for conveying the catheter uncoiled from the disc-shaped catheter bank and is used for withdrawing the catheter into the disc-shaped catheter bank; the guide wire conveying mechanism is arranged on the base and is usedfor conveying and withdrawing a guide wire; and the guide wire conveying mechanism is connected with the near end of the catheter to enable the guide wire to penetrate into the catheter from the nearend of the catheter; the catheter guide mechanism comprises a driving part; and the driving part is rotationally arranged on the base and is synchronously rotated with the disc-shaped catheter bank todrive and change the extension direction of the catheter.

The invention relates to a method for manufacturing a hydrophilic lubricating coating on the surface of a medical interventional catheter. The surface of the catheter undergoes plasmid processing and acrylic acid grafting, so that the surface contains active carboxyl; and then, a dual-layer coating system is constructed, so that a multi-component cross-linked structure is formed, wherein a polyisocyanate curing agent functions as a cross-linking agent for connecting the carboxyl in the surface of the catheter, polyurethane in the coating and a hydrophilic polymer, namely poly (vinyl methyl ether)-maleic anhydride, so that the bottom of the coating is in covalent bond connection with the catheter and the bottom of the coating is firmly combined with the top of the coating; and the coating surface is hydrophilic and lubricant and is firm and wear-resistant as well, and is suitable for hydrophilic lubrication treatment of such instruments as the interventional catheter and the like in the endovascular intervention diagnosis and treatment technology.

The invention relates to a paint for forming an interpenetrating-polymer-network hydrophilic coating, and preparation and application methods thereof. The paint comprises a prime paint and a top paint; the prime paint comprises aqueous polyurethane, a multi-functionality aziridine derivative and deionized water; and the top paint comprises side carboxyl polyurethane, polymethyl vinyl ether-maleic anhydride, acrylic acid, hydroxyl ethyl acrylate, a multi-functionality acrylate derivative, a radical initiator and an organic solvent. During curing, all the components form an interpenetrating polymer network structure, so the coating has excellent hydrophilic lubricity and wear resistance, and is applicable to hydrophilic lubrication treatment of intervention apparatuses used in the technical field of endovascular intervention diagnosis and treatment.

The invention relates to a paint for forming a hydrophilic coating on the surface of a catheter, and preparation and application methods thereof. The paint comprises a prime paint and a top paint; the prime paint comprises aqueous polyurethane, a multi-functionality aziridine derivative and deionized water; and the top paint comprises side carboxyl polyurethane, polymethyl vinyl ether-maleic anhydride and an organic solvent. During curing, all the components form a crosslinking structure; the bottom and the top of the coating are tightly bonded through a covalent bond, and the coating is firmly adhered on the surface of the catheter; and the coating has excellent hydrophilic lubricity and wear resistance, and is applicable to hydrophilic lubrication treatment of apparatuses like an intervention catheter for TCM treatment in the technical field of endovascular intervention diagnosis and treatment technology.

The intention relates to a system (1) and a corresponding method for automatic roadmapping for endovascular interventions. In order to enable an enhanced roadmapping visualization without unnecessary device-footprints, the system (1) comprises: an x-ray imaging device (3) for acquiring x-ray images and a calculation unit (5). The x-ray imaging device (3) is adapted for acquiring a first x-ray image (21) with an interventional device (17) present in the vessels (19) while no contrast agent is present in the vessels (19). Furthermore, the x-ray imaging device (3) is adapted for acquiring a second x-ray image (23) with the interventional device (17) present in the vessels (19) while contrast agent is present in the vessels (19). The calculation unit is adapted for creating a roadmap image (27) by subtracting the first x-ray image (21) from the second x-ray image (23). Moreover, the calculation unit (5) is adapted for automatically minimizing the visibility of the interventional device (17) in the roadmap image (27). A display unit (7) is adapted to display the roadmap image (27) or an overlay of a current fluoroscopy image (31) with the roadmap image (27).

Wound closure apparatus is provided including a body having an elongated, lowermost force-transmitting surface operable to be placed in a proximal, external, wound-closing position on a patient, together with a force-exerting assembly coupled with the body and operable to exert a downwardly directed force serving to generate wound-closing pressure against the patient's tissue. The force-transmitting surface is preferably three-dimensionally asymmetric so that forces of different magnitude are exerted at different locations along the length of the surface. The apparatus is especially designed for the closure of wounds attendant to endovascular interventions, e.g., a femoral artery puncture wound incident to percutaneous cardiac intervention (PCI), and is capable of quickly effecting wound closure with a time-to-ambulation (TTA) of approximately 60 minutes, and with a very low complication rate.

The invention relates to the field of medical materials and discloses a heat-insulating coating material for medical catheters and a preparation method and application of the heat-insulating coating material. The heat-insulating coating material contains biopolymers and hollow silica nanospheres and is prepared with the method including: adding the hollow silica nanospheres to an aqueous solutionof biopolymers with the mass volume fraction of 6%-7% by stirring; meanwhile, adding a plasticizer of 1%-2% volume relative to a silk fibroin solution. When the heat-insulating coating material is applied to the endovascular intervention-like medical catheters, and a heat insulating coating formed by the heat-insulating coating material can effectively slow down the heat exchange rate between perfusion fluid and blood in the catheters, reduce the temperature difference between inlet and outlet perfusion liquid of the catheters and improve the effectiveness and accuracy of local targeted therapy.

A catching device for foreign matter in a blood vessel is composed of a micro guide wire A and a micro guide wire B. The micro guide wire A is magnetic, the micro guide wire B has ferromagnetism and is non-magnetic, and the catching device is formed by matching the micro guide wire A and the micro guide wire B. The invention further provides a catching method of the catching device. The method comprises the steps that firstly, the micro guide wire A penetrates through a clearance of the shifted foreign matter; then, the micro guide wire B penetrates through other clearances of the shifted foreign matter; then, the tail end of the micro guide wire A is used for attracting the tail end of the micro guide wire B, the two micro guide wires are rotated at the same time, and the shifted foreign matter is tightly wound and entangled; finally, the two micro guide wires are pulled out at the same time, and the foreign matter is pulled out of the blood vessel. The device and method are suitable for the situation that in endovascular intervention operations, spring rings and other operational materials shift and fall off to block the normal blood vessel, and the catching device catches the foreign matter firmly, easily, conveniently and safely, safe and good in operation stability, low in damage to the blood vessel, and suitable for micro blood vessels capable of being reached in all the interventional operations.

Wound closure apparatus is provided having a force-transmitting surface operable to be placed in a proximal, external, wound-closing position on a patient, together with a force-exerting assembly operable to exert a wound-closing pressure against the patient's tissue. The force-transmitting surface is preferably three-dimensionally asymmetric to generate different forces along the length of the surface. The apparatus is especially designed for the closure of wounds attendant to endovascular interventions, e.g., a femoral artery puncture wound. The apparatus is positioned and operated so as to partially close the patient's artery upstream of the arteriotomy. The apparatus and methods hereof may also be used for the closure of wounds created during venous intervention procedures. A smaller wound closure apparatus is provided for the closure of brachial and radial wounds, and has a wrist or arm strap for securing the apparatus onto the wrist or bicep region of a patient.

The invention discloses a drug coating stent based on HIV protease inhibitor saquinavir. The drug coating stent comprises a base support and a drug coating which coats the surface of the base support, wherein a drug and a base material are contained in the drug coating; the drug comprises saquinavir. The invention also discloses a preparation method of the drug coating stent: adding the polymer base material and the drug to water, and uniformly mixing to prepare uniform colloidal sol; then soaking the base support in the colloidal sol, and then forming a film through drying and curing to obtain the drug coating support. The drug coating stent based on HIV protease inhibitor saquinavir is applied to endovascular intervention operations, and can control vascular inflammation and prevent the occurrence of vascular restenosis.