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38 results about "Decreased immune function" patented technology
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Immunodeficiency Due to Malnutrition. Deficiency in certain vitamins and minerals can lead to decreased immune system function. Vitamins A, E and C, along with zinc, copper, iron and selenium, have all been shown to be important for either neutrophil, T cell, or antibody function.
Nutritional preparation comprising ribose and folic acid and medical use thereof
Trauma, surgery, inflammation, subfertility, lactation problems, gut disorders, infant nutrition, cancer, arthritis and other joint problems, vascular problems and cardio-or cerebro vascular problems, ischaemia, aging, impaired immune function, burns, sepsis, malnutrition, problems with liver or kidneys, malaria, cystic fibrosis, migraine, neurological problems, respiratory infections, improvement of sports results, muscle soreness, drug intoxication and pain can be treated with a nutritional composition containing effective amounts of ribose and folic acid, optionally combined with other components such as niacin, histidine, glutamine, orotate, vitamin B6 and other components.
Owner:NV NUTRICIA
Shiweifuzheng medicine for tonifying qi and blood, warning yang and strengthening spleen and its prepn process
ActiveCN1682992ADefinite curative effectReduce the side effects of radiotherapy and chemotherapyDigestive systemUnknown materialsSide effectWhite blood cell
The present invention relates to a kind of Chinese medicine with functions of nourishing vital energy, warming Yang and invigorating spleen and its preparation process. The medicine is prepared with ten kinds of Chinese medicinal materials, including ginseng, prepared rhizome of rehmannia, white atractylodes rhizome, astragalus root, tuckahoe, white peony root, angelica, etc. The Chinese medicine with functions of nourishing vital energy, warming Yang and invigorating spleen is used in treating vital energy and blood deficiency caused by radiotherapy and chemotherapy of tumor patient, can reduce the toxic side effect of radiotherapy and chemotherapy and raise immunity, and has no obvious negative reaction.
Owner:陕西方舟制药有限公司
Safe botanical drug for treating malignant pleural effusion and cancer and increasing immune function
InactiveUS20030152647A1Specific activityInhibit oncogeneBiocideUnknown materialsAbnormal tissue growthAnticarcinogen
Three new safe pharmaceutical compositions in accordance with the present invention are for treatment and prevention of malignant pleural effusion and increase immune function comprise Lan Xiang Xi (LX) and polysaccharide of Dang Gui. Methods of treating and preventing cancer cells include inhibiting oncogenes, increasing activity of tumor suppressor, inducing differentiation of cancer cells, inhibiting cancer cells proliferation, inducing apoptosis of cancer cells, inhibiting growth of transplanted cancer and inhibiting cancer incidence, etc. In general, anticancer drug always decreases immune function. However, LX and LX+PDG can inhibit cancer also increase immune function at the same time. Also, LX and DG containing soybean-liposomes is safer than LX and DG.
Owner:LIU YAGUANG
Fluorogenic quantitative PCR method for detecting interleukin 2 gene expression in peripheral-blood under physiological state
InactiveCN1629315AHigh detection sensitivityMicrobiological testing/measurementBiological testingWhite blood cellQuantitative determination
The invention provides a method for performing quantitative determination to immunity-relating cytokine in peripheral blood, the method can be applied for specifically detect the cytokine gene expression (IL-2) from 2ml of peripheral blood, and no any stimulation is needed before detection. The method can detect the cytokine gene expression under physiologic status, thus can be used for determining early stage fatigue, preventing decrease of body immunity function caused by exercises of excess sport load. The invention also provides a corresponding detection kit.
Owner:SHANGHAI UNIV OF SPORT
Application of pine needle fat-soluble extract to preparation of tumor treating medicament
InactiveCN102614228ARich sources of medicineWide variety of sourcesAntineoplastic agentsConiferophyta medical ingredientsImmunologic functionChlorophyllin
The invention provides an application of a pine needle fat-soluble extract to preparation of a tumor treating medicament. The pine needle fat-soluble extract is prepared by performing steps such as extraction, concentration, saponification and the like on a nonpolar solvent, and contains bioactive substances such as chlorophyll, a derivative thereof, carotenoid, multiple fat-soluble vitamins, polypentenol, terpene, phytosterin and the like. As proved by an animal experiment, the pine needle fat-soluble extract has a remarkable tumor inhibiting effect on mouse transplanting S180 sarcomas, has a remarkable cooperative and synergistic action when used together with cyclophosphamide, can be used for remarkably enhancing immunologic function degradation caused by tumor-bearing mice and cyclophosphamide chemotherapy, and has the effects of inhibiting tumor growth, enhancing the curative effect of an anticancer medicament, regulating the immunologic function of an organism, and the like. The pine needle fat-soluble extract can be used for preparing a tumor medicament, and can be taken as an auxiliary synergy and detoxification preparation of an antitumor medicament.
Owner:INST OF CHEM IND OF FOREST PROD CHINESE ACAD OF FORESTRY
Fluorogenic quantitative PCR method for detecting interleukin 4 gene expression in peripheral-blood under physiological state
InactiveCN1629316AHigh detection sensitivityMicrobiological testing/measurementBiological testingWhite blood cellQuantitative determination
The invention provides a method for performing quantitative determination to immunity-relating cytokine in peripheral blood, the method can be applied for specifically detect the cytokine gene expression (IL-4) from 2ml of peripheral blood, and no any stimulation is needed before detection. The method can detect the cytokine gene expression under physiologic status, thus can be used for determining early stage fatigue, preventing decrease of body immunity function caused by exercises of excess sport load. The invention also provides a corresponding detection kit.
Owner:SHANGHAI UNIV OF SPORT
High-adhesion-property Lactobacillus helveticus strain with immunity enhancement function and application thereof
ActiveCN111254087AExcellent Adhesive PropertiesStrong adhesionMilk preparationBacteriaBiotechnologySpecific immunity
The invention belongs to the technical field of microorganisms, and discloses a high-adhesion-property Lactobacillus helveticus strain with an immunity enhancement function. The Lactobacillus helveticus strain is named WHH2580, and is preserved in the China General Microbiological Culture Collection Center since October 23, 2019 under the preservation number of CGMCC No. 18730. The Lactobacillus helveticus strain has a classification name of Lactobacillus helveticus. The invention further discloses application of the Lactobacillus helveticus strain. The Lactobacillus helveticus strain disclosed by the invention has excellent adhesion property in both active form and inactivated form, and is capable of enhancing body immunity by improving and regulating organ index of the body as well as nonspecific immune response and specific immune response. Moreover, the Lactobacillus helveticus strain disclosed by the invention has immunity regulation effects such that corresponding compositions can be ingested so as to improve decreased immune functions by activating the immune functions.
Owner:HANGZHOU WAHAHA TECH +1
Fluorogenic quantitative PCR method for detecting perforin gene expression in peripheral-blood under physiological state
InactiveCN1629312AHigh detection sensitivityMicrobiological testing/measurementBiological testingQuantitative determinationPcr method
The invention provides a method for performing quantitative determination to immunity-relating cytokine in peripheral blood, the method can be applied for specifically detect the cytokine gene expression (PFR) from 2ml of peripheral blood, and no any stimulation is needed before detection. The method can detect the cytokine gene expression under physiologic status, thus can be used for determining early stage fatigue, preventing decrease of body immunity function caused by exercises of excess sport load. The invention also provides a corresponding detection kit.
Owner:SHANGHAI UNIV OF SPORT
Medicine for treating psoriasis and preparation method for medicine
ActiveCN102743661ANo dependencyDermatological disorderPlant ingredientsSalvia miltiorrhizaPittosporum tobira
The invention discloses a medicine for treating psoriasis and a preparation method for the medicine. The preparation method comprises the following steps of: decocting radix rehmanniae, processed pangolin, rhizoma smilacis glabrae, Angelica sinensis, Salvia miltiorrhiza, radix sophorae flavescentis, subprostrate sophora, pittosporum tobira, golden cypress, cortex mori radices, fructus forsythiae, Caulis Spatholobi, radix scutellariae, pericarpium granati, spina gleditsiae, cortex dictamni, Cyrtomium fortune, cortex moutan, Eclipta alba, Kyllinga brevifolia, tuber fleeceflower stem and liquorice in water to obtain a decoction; concentrating, and then, adding conventional auxiliary materials; adding purified water until the crude drug content is 1g / ml; encapsulating; and sterilizing to prepare an oral liquid preparation. The medicine disclosed by the invention is an effective prescription used for specially treating the psoriasis and can be used for dispelling wind and eliminating dampness, nourishing Yin and dredging collaterals, activating blood and dissolving stasis and improving psoriasis symptoms caused by endocrine disorders and diminished immunologic functions. Through clinical observation, the effective rate of the medicine is 100 percent. The medicine for treating the psoriasis is natural and pure and is safe and nontoxic and does not have dependency.
Owner:郭辰玉
Human cytomegalovirus active infection rapid detection method and reagent kit for detection method
ActiveCN104634976AAccurate diagnosisBiological material analysisImmunoglobulins against virusesOlder peopleWilms' tumor
The invention discloses a human cytomegalovirus active infection rapid detection method and a reagent kit for the detection method. The human cytomegalovirus active infection rapid detection method and the reagent kit are mainly used for rapidly monitoring and diagnosing of human cytomegalovirus active infection of pregnant women, newborn and people with immunocom promise including transplantation patients, HIV suffers, tumor patients, diabetics patients and the old people with the immune function decreased due to the age factor. The invention also relates to the preparation of a reagent kit utilizing the detection method.
Owner:BIOHIT BIOTECH HEFEI
Pharmaceutical composition of Qishen in use for treating leucopenia, and preparation method
InactiveCN101049344AGood treatment effectEasy to adjustBlood disorderPlant ingredientsTraditional medicineActive ingredient
A composite Chinese medicine in the form of concentrated liquid for treating leukocytopenia is prepared from astragalus root, mulberry fruit, Chinese angelica root and ganoderma. Its preparing process is also disclosed.
Owner:JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
Fluorogenic quantitative PCR method for detecting gamma interferon gene expression in peripheral-blood under physiological state
InactiveCN1629314AHigh detection sensitivityMicrobiological testing/measurementBiological testingQuantitative determinationGamma interferon
The invention provides a method for performing quantitative determination to immunity-relating cytokine in peripheral blood, the method can be applied for specifically detect the cytokine gene expression (IFN-gamma) from 2ml of peripheral blood, and no any stimulation is needed before detection. The method can detect the cytokine gene expression under physiologic status, thus can be used for determining early stage fatigue, preventing decrease of body immunity function caused by exercises of excess sport load. The invention also provides a corresponding detection kit.
Owner:SHANGHAI UNIV OF SPORT
Pharmaceutical composition for treating cardiovascular and cerebrovascular diseases, preparation process and quality control method thereof
The invention provides a pharmaceutical composition for treating cardiovascular and cerebrovascular diseases, its preparing process and quality control method, wherein Troxerutin and barren wort flavones are employed in combination to obtain various dose forms of injections and oral administration preparations. The composite preparation is mainly used for treating coronary disease, angina pectoris, arrhythmia, cerebral thrombus, cerebral ischemia, hypertension, thrombotic phlebitis, capillary vessel hemorrhage, and decreased immune function.
Owner:BEIJING QI YUAN YI DE PHARMA RESEARCH CENTER
Fluorogenic quantitative PCR method for detecting gamma interferon gene expression in peripheral-blood under physiological state
InactiveCN1300334CHigh detection sensitivityMicrobiological testing/measurementBiological testingQuantitative determinationGamma interferon
The invention provides a method for performing quantitative determination to immunity-relating cytokine in peripheral blood, the method can be applied for specifically detect the cytokine gene expression (IFN-gamma) from 2ml of peripheral blood, and no any stimulation is needed before detection. The method can detect the cytokine gene expression under physiologic status, thus can be used for determining early stage fatigue, preventing decrease of body immunity function caused by exercises of excess sport load. The invention also provides a corresponding detection kit.
Owner:SHANGHAI UNIV OF SPORT
Traditional Chinese medicinal composition for balancing and nourishing, and preparation method and application thereof
InactiveCN104127746AEffectively regulate listlessnessEffectively regulates weakness and fatigueNervous disorderDigestive systemOral ulcersWeakness
The invention discloses a traditional Chinese medicinal composition for balancing and nourishing. Effective components of the traditional Chinese medicinal composition are prepared by using the following raw materials, by weight, 1-40 parts of Dendrobium officinale, 1-40 parts of Semen Euryales, 1-40 parts of coix seed, 1-40 parts of white hyacinth bean, 1-40 parts of lotus seed, 1-40 parts of Chinese yam, 1-40 parts of jujube, 1-40 parts of longan and 1-40 parts of lily. The traditional Chinese medicinal composition for balancing and nourishing is safe and nontoxic and contains no chemical preparations. Clinic experiments prove that the traditional Chinese medicinal composition for balancing and nourishing can effectively adjust listlessness, physique weakness, insomnia, restless sleep, immunity decrease, anorexia, forgetfulness, frequent colds, easy infection of oral ulcers, and other symptoms, and the effective rate reaches above 85%.
Owner:湖南龙石山铁皮石斛基地有限公司
Gynecology anti-microbial repair gelatin formula and preparing method thereof
The invention discloses a gynecology anti-microbial repair gelatin formula and a preparing method thereof. The gynecology anti-microbial repair gelatin formula comprises, by mass, 2.5%-6% of seabuckthorn all-fruit oil, 1%-5% of moisturizing agent, 1.5%-3% of thickening agent, 0.1%-0.5% of PH modifier, and the balance purified water. According to the gynecology anti-microbial repair gelatin formula and the preparing method thereof, the anti-microbial repair gelatin which is good in stability and excellent in anti-microbial repair effect is provided, seabuckthorn all-fruit oil and carboxymethyl chitosan are adopted as main active components in the gelatin, the carcinogenic risk after long-term use of chemical hormone agents is avoided, and the situation that immunologic functions of human organs is lowered due to accumulation of agents is avoided at the same time.
Owner:吉林市宸昊生物科技有限公司
Fructose-contained astragalus oral liquid
InactiveCN101919900AImprove efficacyImprove the effect of adjuvant therapyOrganic active ingredientsMetabolism disorderFructoseTreatment effect
The invention relates to fructose-contained astragalus oral liquid which is prepared from the following raw materials in parts by weight: 5-10 parts of fructose, 30-40 parts of astragalus extract, 1-1.5 part of stabilizer and 100 parts of purified water. By adding the extract liquid of traditional Chinese medicine astragalus, the fructose-contained astragalus oral liquid enhances the drug effects and has favorable auxiliary treatment effect on patients with decreased immune functions due to diabetes or after burn and scald operations.
Owner:沈颂华
A strain of Lactobacillus helveticus with high adhesion performance and its application for enhancing immunity
ActiveCN111254087BExcellent Adhesive PropertiesStrong adhesionMilk preparationBacteriaBiotechnologySpecific immunity
The invention belongs to the technical field of microorganisms. The invention discloses a strain of Lactobacillus helveticus with high adhesion performance that has the function of enhancing immunity. The number is: CGMCC No.18730. The microbial taxonomy is named Lactobacillus helveticus. The invention also discloses the application of the Lactobacillus helveticus with high adhesion performance which has the function of enhancing immunity. In the present invention, both the live bacterial form and the inactivated form of the bacterial strain have excellent adhesion properties, and improve the immunity of the body by improving the organ index, non-specific immunity and specific immune response of the regulation body; the lactobacillus of the present invention has immune regulation If the corresponding composition is taken, it can improve immune function decline by invigorating immune function.
Owner:HANGZHOU WAHAHA TECH +1
Fluorogenic quantitative PCR method for detecting interleukin 4 gene expression in peripheral-blood under physiological state
InactiveCN1300336CHigh detection sensitivityMicrobiological testing/measurementBiological testingWhite blood cellQuantitative determination
The invention provides a method for performing quantitative determination to immunity-relating cytokine in peripheral blood, the method can be applied for specifically detect the cytokine gene expression (IL-4) from 2ml of peripheral blood, and no any stimulation is needed before detection. The method can detect the cytokine gene expression under physiologic status, thus can be used for determining early stage fatigue, preventing decrease of body immunity function caused by exercises of excess sport load. The invention also provides a corresponding detection kit.
Owner:SHANGHAI UNIV OF SPORT
Composition with anti-aging activity as well as preparation and application thereof
ActiveCN114344289ASlow down natural agingNo obvious side effectsCosmetic preparationsNervous disorderQuercetinDecreased immune function
The invention belongs to the field of medicines, and particularly relates to a composition with anti-aging activity, a preparation of the composition and application of the composition in resisting aging and aging-related symptoms. Specifically, the composition disclosed by the invention is mainly composed of a GPX4 agonist and a 15-LOX inhibitor, and vitamin E is supplemented to achieve a synergistic effect. Wherein the GPX4 agonist is prepared from one or more of 6-gingerol, 8-gingerol and 10-gingerol; the 15-LOX inhibitor is prepared from one or more of quercetin, baicalein, eugenol, nobiletin, sweet orange flavone and tangeretin. The composition and the preparation thereof can relieve age-related natural skin aging and accelerated skin aging caused by external adverse factors; meanwhile, the traditional Chinese medicine composition has a certain curative effect on body aging-related symptoms such as cognitive memory decline and immune function decline, and has no obvious side effect.
Owner:JINAN UNIVERSITY
Immunostimulator for animals and humans, and method of preventing animal and human infectious diseases and cancer
InactiveUS7182962B2Reduce probabilityAvoid infectionOrganic active ingredientsBiocideMarked effectMammal
The goal of the present invention is to provide substances to prevent diseases by activating inherently possessed functions, for cultured fishes and shellfishes and livestock with tendency of decreased immune function due to densely populated breeding environment, and for humans with tendency of easily lowered immune functions due to complicated social structures and aging. The present invention expresses marked effect in preventing infection and cancer by administrating appropriate dose of swine plasma, swine plasma albumin, peptides isolated from swine plasma and swine plasma albumin, and swine plasma mixture, among others including fine powder of Crustacea (including crust of Crustacea), to activate immune function of Crustacea, Pisces, Aves, Mammals, and humans.
Owner:A.P.C.
Application of traditional Chinese medicine composition in preparation of medicine for treating oral ulcer
PendingCN113398206ALowers TNF-alpha levelsEnhance immune functionDigestive systemPlant ingredientsMedicinal herbsOral ulcers
The invention belongs to the technical field of traditional Chinese medicines, and particularly discloses application of a traditional Chinese medicine composition in preparation of a medicine for treating oral ulcer. The traditional Chinese medicine composition comprises 11 medicinal materials such as ginseng stem and leaf total saponins, astragalus membranaceus, rehmannia, Chinese yam, radices trichosanthis, raspberry, radix ophiopogonis, schisandra chinensis, fructus lycii, rhizoma alismatis and poria cocos. The traditional Chinese medicine composition disclosed by the invention can be used for remarkably reducing an area of oral ulcer and effectively reducing a level of TNF-alpha in oral ulcer tissues of rats. For recurrent oral ulcer caused by decline of immune functions of rats, after the composition is adopted for intervention, CD3 + cell level in serum of the rats is increased, and meanwhile, a ratio of CD4 + / CD8 + is up-regulated, indicating that the composition can improve immune functions of rats, effectively treat oral ulcer caused by abnormal immune function, and enrich selectivity of clinical medication.
Owner:LUNAN PHARMA GROUP CORPORATION
Shiweifuzheng medicine for tonifying qi and blood, warning yang and strengthening spleen and its prepn process
ActiveCN1314422CDefinite curative effectImprove immunityDigestive systemSolution deliverySide effectWhite blood cell
The present invention relates to a kind of Chinese medicine with functions of nourishing vital energy, warming Yang and invigorating spleen and its preparation process. The medicine is prepared with ten kinds of Chinese medicinal materials, including ginseng, prepared rhizome of rehmannia, white atractylodes rhizome, astragalus root, tuckahoe, white peony root, angelica, etc. The Chinese medicine with functions of nourishing vital energy, warming Yang and invigorating spleen is used in treating vital energy and blood deficiency caused by radiotherapy and chemotherapy of tumor patient, can reduce the toxic side effect of radiotherapy and chemotherapy and raise immunity, and has no obvious negative reaction.
Owner:陕西方舟制药有限公司
Fluorogenic quantitative PCR method for detecting interleukin 2 gene expression in peripheral-blood under physiological state
InactiveCN1300335CHigh detection sensitivityMicrobiological testing/measurementBiological testingWhite blood cellImmunity
The invention provides a method for performing quantitative determination to immunity-relating cytokine in peripheral blood, the method can be applied for specifically detect the cytokine gene expression (IL-2) from 2ml of peripheral blood, and no any stimulation is needed before detection. The method can detect the cytokine gene expression under physiologic status, thus can be used for determining early stage fatigue, preventing decrease of body immunity function caused by exercises of excess sport load. The invention also provides a corresponding detection kit.
Owner:SHANGHAI UNIV OF SPORT
A kind of medicine for treating psoriasis and preparation method thereof
ActiveCN102743661BNo dependencyDermatological disorderPlant ingredientsSalvia miltiorrhizaPittosporum tobira
Owner:郭辰玉
Non-invasive body immunity function change monitoring method and application thereof
InactiveCN107064479ALow costImprove complianceMaterial analysis by observing effect on chemical indicatorComponent separationDiseaseConcentrations glucose
The invention discloses a non-invasive body immunity function change monitoring method and application thereof. The monitoring method includes steps: (1) collecting a urine sample; (2) detecting the content of glucose in the urine sample; (3) judging body immunity function changes, to be more specific, by taking the content of glucose in urine of a subject in a healthy state as a reference, increasing of the concentration of glucose in urine shows declining of body immunity functions; by taking the content of glucose in urine of the subject in a sub-healthy or diseased state, decreasing of the concentration of glucose in urine shows improving of the body immunity functions. The monitoring method which is non-invasive only requires collection of the urine sample, and low cost in sample acquisition, high compliance and freeness of safety risks are realized. Therefore, the method can be applied to early prediction of occurrence and development of immune hypofunction related diseases or sub-healthy state in medical treatment and health care or assessment of effects of immunity function intervention means.
Owner:SOUTH CHINA UNIV OF TECH
Fermentation composition with immune regulation effect and preparation method of fermentation composition
The invention discloses a fermentation composition with an immune regulation effect and a preparation method of the fermentation composition. The decreased immune function can be inhibited by activating the immune function. Moreover, by regulating the balance of the immune function, excessive immune hyperfunction causing adverse effects on organisms and derivative various adverse symptoms of the organisms can be inhibited.
Owner:温光华
Fluorogenic quantitative PCR method for detecting interleukin 10 gene expression in peripheral-blood under physiological state
InactiveCN1285735CHigh detection sensitivityMicrobiological testing/measurementBiological testingInterleukin 10White blood cell
Owner:SHANGHAI UNIV OF SPORT
Medicament for treating AIDS and improving human immunologic function and preparation method thereof
The invention provides a medicament for treating AIDS and improving a human immunologic function and a preparation method thereof. The medicament comprises the following raw materials by weight: 5 to 50 grams of clerodendrum thomsonae, 5 to 50 grams of gynostemma pentaphyllum, 5 to 50 grams of common andrographis herb, 5 to 50 grams of chromolaena odorata, and 5 to 50 grams of paris polyphylla. The preparation method comprises the following steps of: cleaning the raw materials; steaming the materials for 30 to 60 minutes; drying and grinding the materials into fine powder; and sterilizing the powder to prepare capsules, powder or tablets. The medicament has the unique formula and excellent effect of treating AIDS, and has good effect of improving the immunologic function of a patient who suffers from AIDS. The effective rate of the medicament for treating AIDS reaches 90 percent, and has remarkable effect of enhancing immunologic function and improving the immunity.
Owner:张俊松
Mildewproof formula feed for piglets and production method thereof
InactiveCN112167456AAvoid pollutionInhibition and reduction of mycotoxinsFood processingAnimal feeding stuffMycotoxinPhytase
The invention provides a mildewproof formula feed for piglets. The mildewproof formula feed comprises the following raw materials: a mixed base material, a compound mildewproof agent, a compound intestinal nutrient, compound vitamins, compound trace elements, amino acids, calcium hydrophosphate, sodium chloride, ethoxyquinoline and phytase. The invention further provides a production method for the mildewproof formula feed for the piglets. According to the mildewproof formula feed, the pollution of mycotoxin can be reduced, thus avoiding reactions including weight reduction and immune functionreduction of livestock and poultry.
Owner:SICHUAN WANGDA FEED
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