Application of pine needle fat-soluble extract to preparation of tumor treating medicament

Abstract

The invention provides an application of a pine needle fat-soluble extract to preparation of a tumor treating medicament. The pine needle fat-soluble extract is prepared by performing steps such as extraction, concentration, saponification and the like on a nonpolar solvent, and contains bioactive substances such as chlorophyll, a derivative thereof, carotenoid, multiple fat-soluble vitamins, polypentenol, terpene, phytosterin and the like. As proved by an animal experiment, the pine needle fat-soluble extract has a remarkable tumor inhibiting effect on mouse transplanting S180 sarcomas, has a remarkable cooperative and synergistic action when used together with cyclophosphamide, can be used for remarkably enhancing immunologic function degradation caused by tumor-bearing mice and cyclophosphamide chemotherapy, and has the effects of inhibiting tumor growth, enhancing the curative effect of an anticancer medicament, regulating the immunologic function of an organism, and the like. The pine needle fat-soluble extract can be used for preparing a tumor medicament, and can be taken as an auxiliary synergy and detoxification preparation of an antitumor medicament.

Description

technical field [0001] The invention relates to a new medical application of a fat-soluble extract of pine needles, specifically refers to the application of the fat-soluble extract of pine needles in the preparation of drugs for treating tumors, and belongs to the field of biomedicine. Background technique [0002] In the past 30 years, the morbidity and mortality of tumors have been on the rise. It is predicted that by 2020, with the world population reaching 8 billion, there will be 20 million new cancer cases each year, of which the death toll will reach 12 million. The development of cancer drugs is urgent. At present, more than half of all kinds of antineoplastic drugs used and proven in clinical practice originally come from natural products, especially plant ingredients. However, existing antineoplastic drugs derived from natural products, such as paclitaxel, harringtonine, camptothecin, vincine, vinblastine, colchicine, cantharidin, etc., are often combined with sy...

AI Technical Summary

Problems solved by technology

However, existing antineoplastic drugs derived from natural products, such as paclitaxel, harringtonine, camptothecin, vincine, vinblastine, colchicine, cantharidin, etc., are often combined with synthetic antineoplastic drugs Also, there are serious side effects