The invention discloses a liquid-based thin-layer cell slicer, which includes a sample cup, and the sample cup is sequentially provided with a detachable filter head and a detachable slicer head, and the slicer head includes a slicer tube and a slicer. The production platform arranged in the described production cylinder, the described production platform is provided with protruding from its end surface and opposite to the described filter head cell sedimentation sheet, the outer end of the described production platform is provided with the The outlet pipe communicating with the filter head, the slide tube is provided with a slide slot between the filter head and the slide table, and the cell sedimentation piece protrudes from the slide slot and Adjacent end faces can abut against the slide inserted into the slide slot. In the present invention, sampling, filtration and separation, enrichment of precipitated cells, and transfer of cell tissues to glass slides are completed in one body. There is no need to change the sample cup or transfer samples in the middle, and the liquid-based cell production can be completed only by manually inserting the glass slides. , simple in structure, convenient to use and suitable for popularization.