103 results about "A determinant" patented technology

A computerized method and system for detection and quantification of changes in color on skin or internal tissue or organs within the human body. Digital images of the skin or tissue containing an area of interest are analyzed using the software of the invention, based on at least one channel of the LAB color system. The invention calculates the intensity and distribution of color present within the predetermined area of interest, and results in display of at least one color information attribute. The invention allows color calibration of the image to be performed in relation to a reference label having predetermined colors which surrounds the area of interest, prior to the analysis. The invention allows a threshold analysis to be performed, which graphically depicts the size and location of areas exhibiting significant change in color, which is a determinant factor in medical diagnosis.

A method of data encoding is disclosed. An encoder receives a set of information bits and performs an LDPC encoding operation on the set of information bits to produce a codeword based on a matched lifted LDPC code. The matched lifted LDPC code is based on a commutative lifting group and includes a number of parity bits and a submatrix to determine values of the parity bits. An order of the lifting group (Z) corresponds with a size of the lifting. A determinant of the submatrix is a polynomial of the form: ga+(g0+gL)P, where g0 is the identity element of the group, g0=gL2<sup2>k< / sup2>, and P is an arbitrary non-zero element of a binary group ring associated to the lifting group.

A method for diagnosing or differentially diagnosing a cancer characterized by the presence of cancer cells in the pleural fluid of a mammalian subject, the method comprising contacting a sample of pleural fluid of the subject with colloidal magnetic particles coupled to a ligand which binds to a determinant on a cancer cell, but does not bind above a baseline threshold to other cellular and non-cellular components in pleural fluid; subjecting the pleural fluid-magnetic particle mixture to a magnetic field to produce a cell fraction enriched in ligand coupled-magnetic particle-bound cancer cells, if present in the pleural fluid; and analyzing the enriched fraction for the number of cancer cells in the pleural fluid. In certain aspects, this method involves preparing the pleural fluids for the above-noted method steps by, e.g., dilution of unprocessed pleural fluid. In certain aspect, the pleural fluid is subjected to the diagnostic method within 24 hours of withdrawal from the subject. This method has advantages to present diagnostic procedures for identifying malignant pleural effusions. The tumor cells present in pleural fluid can be characterized with cellular and molecular markers to determine prognostic and predictive factors.

Disclosed are inhibitors of HER3 for the treatment of melanoma, in particular melanoma metastases and / or refractory melanoma, pharmaceutical compositions comprising such an inhibitor and a method for the diagnosis or prognosis of melanoma.

To provided a control method and a controller for an a.c. motor without using a speed sensor in which the speed estimated value or the magnetic flux estimated value of an all-dimensional magnetic flux speed observer can be made to correspond to that of an actual a.c. motor. A controller for an a.c. motor includes a vector control and calculating circuit (7) for controlling and calculating a vector from an exciting current command calculated in an exciting current command calculating circuit (5), a torque current command calculated in a torque current command calculating circuit (6), a coordinate transformed current detected value obtained in a coordinate transformation circuit (4), a speed estimated value and a magnetic flux phase estimated value and outputting an output voltage command, a switching pattern generating circuit (8) for generating a signal for PWM driving a power converter (1) from the output voltage command and an all-dimensional magnetic flux speed observer (9) for estimating the speed estimated value and the magnetic flux phase estimated value from the output voltage command and the coordinate transformed current detected value. In the controller for the a.c. motor, a coefficient correcting circuit 10 is provided for correcting the coefficient of a determinant used in the all-dimensional magnetic flux speed observer (9) in accordance with a magnetic flux command.

The invention discloses a solving method used for dynamic response when an elastic boundary shallow arch generates internal resonance. The method is carried out on the basis of a dimensionless kinetic equation, corresponding rigidity parameters are used for representing the magnitudes of vertical elastic constraint and rotating-direction elastic constraint on the shallow arch, the modality of the elastic boundary shallow arch is supposed through a general solution and a particular solution to a differentiation equation, the natural vibration frequency is obtained due to the fact that a determinant corresponding to a modality coefficient matrix is equal to zero, an average equation in the polar form under the three internal resonance conditions of 1:2, 1:1 and 1:3 is derived through Galerkin discretization of the kinetic equation of the shallow arch and multiscale perturbation analysis, and therefore dynamic response used when the internal resonance is generated can be obtained. Due to the thought that constraint rigidity is considered in the modality and the natural vibration frequency, existing technical problems generated in a dynamic response solving process when the elastic boundary shallow arch generates the internal resonance are solved. Safety and reasonability of the built shallow arch are guaranteed, and the service life of the shallow arch can be prolonged.

The invention discloses an HER2-resistant humanized antibody and a relevant tumor-resistant composition thereof. The HER2-resistant humanized antibody in the tumor resistant composition provided by the invention is an HER2-resistant humanized antibody M1 containing a humanized heavy chain variable region M1-VH and a humanized light chain variable region M1-VL which both consist of a determinant complementary region and a framework region, the determinant complementary regions of the M1-VH and the M1-VL both consist of CDR1, CDR2 and CDR3; the amino acid sequences of the CDR1, the CDR2 and the CDR3 of the M1-VH are respectively shown as the 26th to 35th, the 50th to 66th, and the 99th to 109th of the SEQID No.1; the amino acid sequences of the CDR1, the CDR2 and the CDR3 of the M1-VL are respectively shown as the 24th to 40th, the 56th to 62th, and the 95th to 103th of the SEQID No.2.

The invention discloses a nanometer antibody Nb16 for anti-CTLA-4 and a preparation method and application of the nanometer antibody Nb16. The provided nanometer antibody comprises a determinant complementary region and a frame region. The determinant complementary region of the nanometer antibody includes CDR1, CDR2 and CDR3, wherein the amino acid sequence of CDR1 is the 26-35 amino acid of SEQ ID No.1 in a sequence list, the amino acid sequence of CDR2 is 51<st>-59 amino acid of SEQ ID No.1 in a sequence list, and the amino acid sequence of CDR3 is 97-106 amino acid of SEQ ID No.1 in a sequence list. The nanometer antibody Nb16 can combine with T cells and CTLA-4, and can be used for researching and developing a CTLA-4 molecular detection agent, preparing a tumor inhibitor or a tumor cell inhibitor, and preparing a medicine for inhibiting activity of CTLA-4 and prompting T cell proliferation.

The invention relates to a feature point matching method based on correlation measurement, which comprises: shooting multiple scene images to be matched and inputting the scene images into a computer; calculating gradient of each pixel of the images, and extracting feature point information of the images; for each extracted feature point, dividing a round neighborhood into blocks by taking the feature point as a center, and calculating a gradient mean of each subarea obtained by the dividing step; utilizing the gradient of each pixel point of the subarea and the gradient mean of the subarea to establish a Harris correlation matrix of the subarea and calculate a determinant and a track of the Harris correlation matrix; utilizing the determinant and the track of the Harris correlation matrix to construct a Harris correlation measurement, and utilizing the Harris correlation measurement to construct a Harris correlation descriptor; and calculating Euclidean distance among the descriptors of the feature points, and applying measurement criteria to carry out matching. The method does not need to calibrate parameters of the pickup camera, does not need human participation during matching, automatically finishes matching, and has the characteristics of simplicity, practicality, dense matching points, high matching precision, good robustness and the like.

Consistent with the present disclosure, a method and system for detecting a clock phase of an optical signal in a coherent receiver is provided that is insensitive to polarization mode dispersion (PMD) and other polarization effects in the optical communication system. The clock phase of the received signal is estimated by first calculating a phase shift between a pair of related frequency domain data outputs of a Fourier transform circuit. The calculated phase shift includes a phase component and a data spectrum component. The calculated phase shift is then averaged over a number of clock cycles to remove the data spectrum components thus enabling extraction of the phase component. A determinant function on the time averaged result is used to normalize any effects of PMD from the received signal and isolate the phase component. In this manner, the phase component is not dependent on the PMD effects in the optical communication system. The imaginary part of the phase component is then calculated to estimate the clock phase error which is used to tune an oscillator in the receiver to synchronize a sampling phase in the receiver with the received signal. An estimated value for the chromatic dispersion is determined from a resultant value of the determinant function and used to compensate for the effects of chromatic dispersion from the clock phase error estimate.

The invention discloses an anti-CTLA-4 nano antibody Nb91 and a preparation method and an application thereof. The nano antibody provided by the invention includes a determinant complementary region and a frame region; the determinant complementary region of the nano antibody consists of CDR1, CDR2 and CDR3; an amino acid sequence of the CDR1 comprises 26th-32nd amino acids of SEQ ID NO.7 in a sequence table; an amino acid sequence of the CDR2 comprises 48th-55th amino acids of SEQ ID NO.7 in the sequence table; an amino acid sequence of the CDR3 comprises 94th-106th amino acids of SEQ ID NO.7 in the sequence table. The nano antibody Nb91 can be combined with T cells and CTLA-4, and can be applied to research and development of CTLA-4 molecular detection reagents, preparation of tumor inhibitors or tumor cell inhibitors and preparation of drugs for inhibition of CTLA-4 activity and promotion of T cell proliferation.

Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of a determinant which is set forth in Tables 1 or 2 in a sample derived from the subject, wherein said amount is indicative of the infection type.

The invention discloses a self-adaptive moving electron multiplying CCD video image denoising method. According to the method, bidirectional registering is performed on the reference frame and the current frame of a low-light video sequence by adopting a determinant projection mode, the sum of deviation squares of projection of two sequentially continuous frames of images is calculated and the obtained function of the sum of deviation squares is a function related to displacement, and then the maximum displacement of the two sequentially continuous frames of images is found by traversal of the matrix of the sum of deviation squares; and the overlapped area of the two frames is obtained by the calculated displacement coordinates of the two sequentially continuous frames of images, image information of the overlapped area is not changed after the overlapped area is obtained and noise randomly changes and meets a Gaussian noise model, the displacement direction of the images is judged, bidirectional registering is performed on the images, and then weight filtering is performed to remove noise. Noise of electron multiplying CCD moving videos can be removed, and the image correction effect is great so that a ghost problem caused by the conventional moving video denoising method can be avoided.

The invention discloses a content recommendation model training method, a content recommendation method and a related device, which are used for improving the diversity of recommended content. The method comprises the steps of obtaining first to-be-trained text data at a first moment, the first to-be-trained text data comprising a first text attribute feature and a first text semantic feature; obtaining a first text quality prediction value and a first feature vector corresponding to the first to-be-trained text data through a neural network of the to-be-trained content recommendation model; obtaining a second text quality prediction value and a second feature vector corresponding to second to-be-trained text data at a second moment through the neural network; obtaining a text recommendation probability through a determinant point process according to the first text quality prediction value, the first feature vector, the second text quality prediction value and the second feature vector; and according to the text recommendation probability, training the to-be-trained content recommendation model to obtain a trained content recommendation model.

The invention relates to an amino acid sequence capable of improving heat-resistance temperature and heat stability of SOD and application thereof. The amino acid sequence is an N-terminal amino acid sequence of 13 special thermophilic Fe / Mn-SOD from Geobacillus category. The amino acid sequence has the following features: (1) the amino acid sequence is before the sodA functional domain of Fe / Mn-SOD protein, the sequence length is 101-344 amino acids and the function is unknown; (2) 85-100% of homology exists among the amino acid sequence; (3) one or two peculiar consensus repeats Geo-N-repeat are included. The amino acid sequence can play a determinant role on the heat-resistance temperature and the heat stability of Fe / Mn-SOD of the Geobacillus category, can be widely applied to improvement on other SODs (particularly normal-temperature SOD), and can remarkably improve the heat-resistance temperature and the heat stability.

Sphericity of a structure can be determined using the technology described herein. A system for determining sphericity can include a computer processor configured to compute a covariance matrix for a three dimensional model of a structure. The processor can be configured to calculate a sphericity of the structure using the covariance matrix and a long-axis vector associated with a long axis of the modeled structure. In certain embodiments, the processor can be configured to compute the sphericity as a ratio between a determinant of the covariance matrix and a cubed extent of the model in the long-axis direction. Certain embodiments can include an imaging device, such as an ultrasound scanner, for example, configured to capture an image of the structure and obtain a model of the structure. Certain embodiments can include a user interface configured to allow a user to identify the long axis of the modeled structure.

A steam generator system for rapidly creating steam by a direct conversion of electrical energy to heat in ionic, water molecules. The system generally includes a supply of water having an ionic content to be received by a heating tank for contacting current-carrying electrodes to produce steam in a continuous, intermittent, or a determinant amount, via a control system. Also possibly included are a water reservoir, filter, pump, check valve, and various optional embodiments of the heating tank. The present invention also permits for controlling the supplied current input to the electrodes by the combination of ionic content added to the water, water level as controlled by the pump, and a phase angle controller and current sensor of an electrical circuit.

The invention provides a power generator set controller-based font library dot matrix generation method. The method comprises the following steps of 1: determining fonts about to generate a font library, and sizes; 2: firstly creating a Picture1 control, and creating a Label on the Picture1 control, wherein the position of the Label is set to be (0,0), an AutoSize attribute is set to be true, and the font sizes are set to be the font sizes in the step 1; secondly displaying a to-be-converted font on a label; thirdly putting the label on a Picture, obtaining an RGB value of a coordinate point (x,y) through a Picture.Point (x,y) method, and if the value is 0, determining a dot matrix on the font and calculating the size of a byte array according to the positions of byte bits, wherein the low bits are front and the high bits are back; and 3: obtaining the dot matrix of the font in a determinant scanning mode, and storing the dot matrix in a dat file.

The invention relates to a singularity margin detection method based on a screw space included angle for serial and parallel robot mechanisms. The method comprises the following steps of: on the basis of establishing a robot screw coordinate system and calculating a joint kinematic screw or a branched chain restraining force screw, calculating a determinant of an extension screw matrix, and further expressing the screw space included angle; if the screw space included angle is approximately 90 degrees in a moving process of a robot, considering that the singularity margin of the robot is very small; and if the screw space included angle is approximately zero degree, considering that the singularity margin of the robot is very large. The method is characterized in that: an optimization algorithm is not required, so that the method has a high computational efficiency; the screw space included angle is taken as a singularity margin index, which has a geometric meaning; and the method is suitable for detecting the motion singularity margins of serial robots or serial branched chains, and is suitable for detecting the static singularity margins of parallel robots.

A system for targeted delivery of agents (e.g., molecular probes, diagnostic agents, therapeutic agents, imaging agents, research or analytical compounds, enzymes, peptides, proteins, lipids, lipoproteins, sugars, hormones, vitamins, nucleic acids, viruses, bacteria, and / or cells) including use of a composition containing the agent and a targeting moiety, specific for a determinant at the target location. An exemplary composition of the system includes a targeting moiety of one of peptides γ3, 2γ3, 3γ3, A1, B7, B8, B9, B1O, and D6, specific for targeting ICAM-I. The system enables effective, versatile, and safe targeting and transport of agents. The system is useful in research applications, as well as in the context of translational science and clinical interventions.

A method, a system, and a computer program product for applying a white balance correction to an image data captured by a camera sensor based on a current level of ambient color. The method includes capturing, via a camera sensor, image data of a scene. The method further includes contemporaneously measuring, via a light color sensor, an amount of ambient color. The method further includes calculating a determinant value that represents a magnitude of variance of colors in the scene. The method further includes in response to determining the determinant value is less than a determinant threshold: generating a white balance correction based at least in part on the measured amount of ambient color and applying the white balance correction to the image data to generate a corrected image data having colors that more accurately represent colors in the current scene.

The invention discloses a determinant and sparsity constraint of non-negative matrix factorization (DSNMF) data integrity authentication watermark method of wireless body area network. The DSNMF data integrity authentication watermark method of wireless body area network mainly aims at solving the problem that institute of electrical and electronic engineers (IEEE) 802.15.6.integrity authentication needs to additionally add message authentication codes. The DSNMF data integrity authentication watermark method of wireless body area network comprises two steps: watermark embedment at a sending end and watermark extraction at a receiving end. In the sending end, data feature vector is acquired by DSNMP decomposing processed integer plane matrix of sample data and watermark is generated. Encryption watermark is embedded in the data in parallel, and the sample data are acquired by reconstructing the data. In the receiving end, reference watermark is acquired using the same method with the sending end, the encryption watermark is extracted and deciphered to acquire extracted watermark, the reference watermark and the extracted watermark are compared, and integrity authentication of the data is realized. The DSNMF data integrity authentication watermark method of wireless body area network is capable of saving communication cost required in transmitting 32-bit authentication codes, and reducing energy consumption.

Methods and systems for selecting and performing group actions include selecting parameters for an approximated action-value function, which determines a reward value associated with a particular group action taken from a particular state, using a determinant of a parameter matrix for the action-value function. A group action is selected using the approximated action-value function and the selected parameters. Agents are triggered to perform respective tasks in the group action.

The invention discloses a package structure and a package method for a high definition LED display screen module. The package structure for the high definition LED display screen module comprises a PCB, a plurality of pixel units, QFN circuits, capacitors and driving IC chips, wherein the pixel units are connected to the front face of the PCB and arranged in a determinant mode, the QFN circuits, the capacitors and the driving IC chips are connected to the back face of the PCB, and the central distance between every two adjacent pixel units is 1.5mm. The integral structure of the package structure meets the requirement of the market for the definition of the high definition LED display screen. The package structure is reasonable in layout and high in package precision, the packaged LED display screen module is wide in application range, and the LED display screen module can be used for large screen display of an indoor instruction dispatch system and high definition display of a film screen.