The invention discloses a large vent structure fixing support prepared from a shape memory material through injection molding. A mixed raw material comprises polycaprolactone, a filler and auxiliary materials. In the large vent structure, a ratio of a hollow area to the total area is 7-70%. The large vent structure fixing support is provided with a removable and locking tightness adjustable locking connection device. Preferably, the large vent structure fixing support contains a coupling agent. The fixing support injection molding can realize stretching and curved surface deformation. The large vent structure fixing support has no coating. Through the large vent structure, the change of the illness can be directly observed and the complication after wound is prevented. The large vent structure fixing support can adjust a clamping tightness degree in the whole course of disease, can keep the soft tissue compression, has good fixing effects, is conducive to wound care after an operation,prevents reproduction according to a patient bodily form in use and can be simply operated by a doctor. The material does not suck water, has no liner structure, can be fast dried after a bath, is good in comfort, greatly improves the skin health status, prevents pruritus and dermatitis and can be used for outer fixation of upper limbs, neck, chest, waist and lower limbs.