The invention relates to a graphene cable line which comprises a structure of seven layers, wherein the seven layers are arranged in a sequential laminated manner and comprise a rubber layer, a plastic layer, an insulating tape layer, a first pure cotton gauze layer, a graphene layer, a second pure cotton gauze layer and a steel wire layer in sequence from outside to inside. The invention further relates to a preparation method and a wiring method of a cable line which adopts graphene for power conduction. The graphene cable line, the preparation method and the wiring method provided by the invention have the beneficial effects that the graphene cable line is great in power conduction electric energy, small in power loss, light in weight, soft, small in size, good in corrosion resistance, small in surface area, large in overhead bearing capacity, high in performance cost ratio and long in service life, a great amount of energy, labor and materials can be saved, and the preparation method and the wiring method are simple to operate.