161results about How to "Skin irritation" patented technology

A percutaneous agent delivery or sampling device comprising a sheet having a plurality of microblades for piercing and anchoring to the skin for increasing transdermal flux of an agent and for improving the attachment of the device to the skin.

Methods, apparatus and systems for personal care, such as treatment of a skin or hair treatment surface, are disclosed. In some embodiments, a base device is configured to thermally modify (heat or cool) an applicator on a hand piece that can then be used to cleanse, treat and / or otherwise rejuvenate the treatment surface. The applicator can be formulated with a smooth or abrasive material that can absorb, be coated with or otherwise take up a variety of materials, such as liquids, lotions, gels or creams, which are suitable for application to the treatment surface. The base device may thermally modify the material that is then coupled to the applicator and applied to the treatment surface during treatment. Application of the applicator at the desired temperature to the treatment surface may, for example, stimulate deeper blood circulation, clear pores, diminishes or removes deep and fine wrinkles, accelerate acne clearing, treat blemished skin, decrease edema and erythema of the skin, and / or reduce puritis of various etiologies. The hand piece may comprise one or more secondary treatment elements, such as LEDs for photoactivation, electrodes for delivery of micro-currents or vibrating elements for rubbing or abraiding, in order to achieve additional activation of the treatment surface and / or of the thermally modified material coupled to the applicator, which may enhance or improve treatment.

There is provided a therapeutic medical compression garment with an integrally knit anti-slip portion. The anti-slip portion of the garment is located in the upper area thereof. In the embodiment wherein the garment is a stocking, the anti-slip portion is placed in the thigh area of the thigh-hi stocking or the upper calf area of the knee-hi stocking. In the thigh-hi stockings, the anti-slip section may start just above the knee or be located in the upper thigh area (for use in mobilized patients, the anti-slip section may start already just above) the ankle area, e.g., also in knee-hi stockings at the calves upwards.

Compositions for topical delivery of an active agent and methods for using such compositions are described herein. Compositions include one or more active agents and about 0.001 wt. % to about 10 wt. % of a extracellular matrix component having average molecular weight of about 2,000 daltons to about 20,000 daltons. The extracellular components include hyaluronic acid, collagen, fibronectin, elastin, lectin, and fragments thereof and combinations thereof.

A solid cosmetic comprising components (A), (B), (C), and (D) below: (A) a polyamide resin; (B) diisostearyl malate; (C) a polyglyceryl isostearate; and (D) a liquid oil; and not containing a wax when the component (A) comprises only an ester-terminated polyamide resin.

A percutaneous agent delivery or sampling device comprising a sheet having a plurality of microblades for piercing and anchoring to the skin for increasing transdermal flux of an agent and for improving the attachment of the device to the skin.

Devices and methods for the treatment of skin conditions and lesions are disclosed herein. A thermal device can be used to heat or cool a personal care pack that can then be used to cleanse, treat, and rejuvenate the skin. The personal care pack can be formulated with smooth or abrasive material and can contain a variety of liquids, lotions or gels. Application of the personal care pack, at the desired temperature to the skin can stimulate deeper blood circulation, clear pores, diminishes or removes deep and fine wrinkles, accelerate acne clearing, treat blemished skin, decrease edema and erythema of the skin, and reduce puritis of various etiologies.

The present invention is directed to a device, which can be attached to a subject's skin with an adhesive collar. The device can be a sensor, an actuator or a marker. Preferably, the device is a sensor, and more preferably in the form of a wet or dry electrode sensor, and most preferably, a dry electrode sensor. The invention is used to attach the device to a subject's prepared or unprepared skin so that the device can remain attached to the subject for an extended period of time with minimal skin irritation, breakdown, or re-application, and preferably with no skin irritation, breakdown, or re-application.

The invention discloses an allergy-relieving, anti-inflammatory and anti-irritation skin-care composition, which is mainly prepared from the following raw materials in percentage by mass: 1 to 10 percent of traditional Chinese medicine extract, 1 to 10 percent of irritation inhibiting factor, 1 to 10 percent of anti-allergic antipruritic, 1 to 10 percent of photosensitive restoration agent and the balance of substrate. The raw materials in the skin-care composition are natural soothing components, are natural and mild, have low skin irritation and play a role in resisting inflammation, relieving allergy, restoring and protecting the skin and enhancing skin immunity. The allergy-relieving, anti-inflammatory and anti-irritation skin-care composition is made from readily-available raw materials by a convenient preparation method, has lower cost than that of other anti-allergy methods, is easily accepted by general consumers and has good application prospect and market prospect.

A vehicle for topical application which contains a liquid eutectic mixture of hydrophobic compounds to improve solubility of pharmaceutically active component and enhance topical and transdermal delivery.

I have discovered cosmetic cold-wax hair removal (depilatory) compositions suitable for site-specific face or body applications with the following attributes: (1) A pre-heating or microwave step is not necessary, (2) Complete hair removal is achieved in a single application on a specific site or area, (3), No (or minimal) skin irritation is experienced, (4) Bond to hair preferentially, and not to skin, (5) Provide lubricity and emolliency to skin, (6) Can be applied either directly on the skin or, preferably, on a piece of precut fabric, plastic or paper, which is then applied to specific site where hair removal is desired. Alternatively, dispensing applicators can also be used that can be filled for delivery at the specific site where depilation is desired. (7) Require minimal clean-up with water or common make-up removal compositions, and (9) Additional skin and hair beneficial ingredients, such as hair growth retardants, anti-irritants, topical pain relief agents, antioxidants, skin soothing agents, skin cooling agents, emollients, moisturizers, topical anesthetics, colorants, botanical extracts, fragrances, and such can be included.

An edge coated glass polarized lens includes a lens body and an edge coating made from an UV curable material having a composition including: an aliphatic polyesterpolyol based urethane methacrylate formed by reaction of reactants including an aliphatic polyesterpolyol, a hydroxyalkyl methacrylate, and a diisocynate, and having a number average molecular weight ranging from 800 to 4500; a reactive diluent including a methacrylate monomer; an adhesion enhancer including a silane material selected from methacrylate-functional silane, amino methacrylate-functional silane, vinyl-functional silane, and combinations thereof; and a photo initiator.

Various methods of preparing dry water-soluble polymers are described. Furthermore, water-soluble polymers in solid form are also described.

The present invention provides a cosmetic composition, comprising 0.1 to 5 mass % of a lipopeptide compound, and 0.1 to 20 mass % of a polyoxyethylene glyceryl ether fatty acid ester and / or a polyoxyethylene sorbit fatty acid ester. The cosmetic of the present invention, with an extremely low skin irritating property, ensures high skin comfort and stability. In particular, when used as a cleansing cosmetic, it also exhibits an excellent washability.

An antimicrobial fiber bearing an anionic functional group, and a method of producing it wherein at least a part of the anionic functional group forms a quaternary ammonium salt and at least another part thereof forms an antimicrobial metal salt. The quaternary ammonium salt is preferably a cetylpyridinium salt, and the antimicrobial metal salt is preferably a zinc salt. The fiber is preferably a carboxyalkylated cellulose fiber. An antimicrobial fiber product comprising the antimicrobial fiber.

[Objective] To provide a pressure-sensitive adhesive agent for skin containing a pressure-sensitive adhesive agent for skin that has favorable shape retention properties and skin-follow up properties without being adversely affected by moisture from excrement or the like even when adhered to the skin over a long period of time and yet leaves no adhesive residue after separation and a pressure-sensitive adhesive sheet for skin contains a base material and a layer of the pressure-sensitive adhesive agent for skin.[Means to Achieve Objectives] A pressure-sensitive adhesive agent for skin contains 2 to 35% by weight of a thermoplastic elastomer, 25 to 60% by weight of a hydrophilic polymer compound, 16 to 40% by weight of a softener, and 0.01 to 4.8% by weight of a physiologically active agent; and has a water absorption 3 hours after of 55 to 240% and a water absorption 24 hours after of 240 to 450%. A pressure-sensitive adhesive sheet for skin contains a base material and a layer of a pressure-sensitive adhesive agent for skin that contains 2 to 35% by weight of a thermoplastic elastomer, 25 to 60% by weight of a hydrophilic polymer compound, 16 to 40% by weight of a softener, and 0.01 to 4.8% by weight of a physiologically active agent and is formed on one side of the base material; and has a water absorption 3 hours after of 55 to 240% and a water absorption 24 hours after of 240 to 450%.

A deshedding tool (10) for removing hair from a pet includes a handle (13) which carries a blade holder (14). A blade assembly (20) is carried by the blade holder (14). The blade assembly (20) includes a plurality of sawtooth blade segments (21) and a plurality of blade guards (22). The blade segments (21) and the blade guards (22) alternate with each other, and the blade guards extend outwardly from the blade holder (14) and downwardly from the blade holder (14) farther than the blade segments (21).

This invention relates to a method for enhancing the transmembrane penetration of benefit agents using a certain non-ionic lipid / surfactant-containing formulation as an enhancing agent, and the compositions used therein. Various active agents, such as anti-dandruff agents, hair growth agents, hair inhibitor agents, anti-acne agents, anti-aging agents, depilatory agents, and depigmentation agents, may be effectively delivered into the skin, hair follicles and sebaceous glands using the compositions of the present invention.

It is an object to provide an antiviral agent that can be used for persons having sensitive skin or on the face, inactivates viruses such as a norovirus and an influenza virus, and is excellent in germicidal properties. Further provided is a cleansing agent that does not lead to environmental pollution since the cleansing agent is easily decomposed in the natural environment, scarcely causes eczema and allergic dermatitis since no germicidal agent is added, and has an antiviral performance. The antiviral agent containing a surface-active agent having a C18 unsaturated alkyl group as an active component. It is not always necessary to lather or rinse off with water like cleansing agents such as medicated soaps since the antiviral agent of the present invention at a very low concentration can inactivate the virus.

The invention relates to a hygienic insecticide, in particular to hygienic insecticide microcapsules and a preparation method thereof. Each hygienic insecticide microcapsule comprises a capsule core and a capsule wall, wherein the capsule core is hygienic insecticide technical, and the capsule wall is made of a polymer material. The biodegradable polymer substances are taken as capsule wall materials, easily recycled organic solvents are selected, and the novel hygienic insecticide microcapsules with a slow release function are prepared by controlling the condition. The hygienic insecticide microcapsules have the characteristics that the microcapsules are illumination-resistant, acid-resistant and alkali-resistant, slow release is realized, skin irritation is reduced and the like.

A garment seam is formed between two fabric panels by abutting the edges of at least two panels and placing a strip of material carrying adhesive on the abutted edges to form the seam. The fabric panels have opposing major surfaces, the edges of the fabric panels being minor surfaces. The strip of material is applied on at least one major surface of the abutted fabric panels, but is optionally applied to both major surfaces of the abutted fabric panels. The strip of material is preferably thinner than the fabric panels. In some embodiments, the adhesive is a thermosetting adhesive that is applied on the strip of material in liquid form. A seam manufactured according to the present invention is less detectable through clothing than conventional multi-ply seams. Also the adhesive seam enables the manufacturer to tailor the garment to provide support or shape in a particular area (i.e. the area of the seam) in addition to providing the desirable smooth appearance. For example, when used in a brassiere (bra) cup, the seam allows the garment to be designed to provide optimal comfort, shape and support to the wearer.

A deshedding tool (10) for removing hair from a pet includes a handle (13) which carries a blade holder (14). A blade assembly (20) is carried by the blade holder (14). The blade assembly (20) includes a plurality of sawtooth blade segments (21) and a plurality of blade guards (22). The blade segments (21) and the blade guards (22) alternate with each other, and the blade guards extend outwardly from the blade holder (14) and downwardly from the blade holder (14) farther than the blade segments (21).

The invention discloses propranolol hydrochloride submicron emulsion gel and a preparation method and application thereof. The propranolol hydrochloride submicron emulsion gel comprises propranolol hydrochloride and pharmaceutical acceptable medicinal excipients, wherein the medicinal excipients comprise oil, a surfactant, a cosurfactant, a penetration enhancer, a gel substrate, a pH conditioning agent and the balance water. The propranolol hydrochloride submicron emulsion gel can efficiently deliver the propranolol hydrochloride to skin tissue to enable drugs to be released slowly, skin targeted drug delivery treatment on superficial infantile hemangioma is achieved, and the problems that for an existing drug, the curative effect is low, the side effect is large, and the transdermal absorption ratio is low are effectively solved.

The present invention relates to a thermoplastic silicone-polyurethane elastomer and a method for preparing the same. The elastomer is prepared from raw materials comprising: 25-80 parts of a macromolecular polyol, 0-60 parts of a silicone oil or a liquid silicone rubber, 10-50 parts of a diisocyanate, 3-20 parts of a small molecular diol as a chain extender, and 0.1-3 parts of an auxiliary agent. The macromolecular polyol is selected from a silicon-free polyol having a molecular weight of between 1,000 and 4,000 g / mol and a polyol modified by silicone through copolymerization or grafting. The small molecular diol is a small molecular diol comprising 10 or less carbon atoms. The thermoplastic silicone-polyurethane elastomer of the present invention has the following excellent performance parameters: a hardness of Shore A40-D80; a tensile strength ≥5 MPa; smooth hand feeling; resistance to dirt such as dust; resistance to liquid permeation; no irritation to skin; good encapsulation effect on PC, ABS, TPU and the like; and a 180° peel strength >25 N / 25 mm.

The present invention is for a method of treatment for joint pain and other discomfort utilizing a brush applied to the skin of the patient. The brush is used to stimulate the skin in the area of pain or discomfort, thereby conditioning the nerves in the area to be less responsive to the aforementioned pain or discomfort.

It is an object of the invention to provide a crosslinkable pressure-sensitive adhesive for skin that exhibits satisfactory adhesion and releasability for human skin and low irritation to skin, and a crosslinkable pressure-sensitive adhesive sheet for skin that is suitable for medical and cosmetic use, as well as to provide a composition for production of a crosslinkable pressure-sensitive adhesive for skin that has superior storage properties and is suitable for preparation of the crosslinkable pressure-sensitive adhesive for skin. The crosslinkable pressure-sensitive adhesive for skin of the invention is formed by 100 parts by weight of an acrylic copolymer (copolymer A) comprising a (meth) acrylic acid alkyl ester as the main constituent component and 3-45 wt % diacetoneacrylamide as an essential constituent component, and containing no free carboxyl groups, and 0.1-30 parts by weight of an acrylic copolymer (copolymer B) comprising a (meth)acrylic acid alkyl ester as the main constituent component and a primary amino group and / or carboxyhydrazide group on a side chain, and containing no free carboxyl groups. A composition of copolymer A and copolymer B dissolved in a solvent containing at least 5.0 wt % acetone and / or butanone with respect to the total amount of solvent can be stored for prolonged periods.