The invention relates to the technical field of fire rescue, in particular to a high-rise fire self-rescue rescue device, which includes a support frame, a storage mechanism, an installation mechanism, a connection mechanism, a partition, a limit mechanism, a water storage mechanism, a lifting mechanism, a closing mechanism and The fixing mechanism, the storage mechanism is fixed on the wall through the support frame, the installation mechanism and the lifting mechanism are installed on the top of the storage mechanism, the lifting mechanism is rotated to make the rope hang down from the floor, and the connecting mechanism is installed inside the storage mechanism, and the connecting mechanism fixes the person and the rope together. Make people slide down from the rope, which is convenient for people to escape from fire; a partition is installed inside the storage mechanism, masks and other items are placed in the partition, and a water storage mechanism is installed above the partition, and the water storage mechanism is opened to make the water inside the water storage mechanism Sprinkle on the mask, wet the mask to prevent smoke and dust from entering the mouth; install a limit mechanism on the side wall of the lifting mechanism, and the limit mechanism engages with the installation mechanism to fix the lifting mechanism inside the installation mechanism to prevent the rope from being untied.