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42results about How to "Maximize resolution" patented technology

Overlay error detection

An overlay target with gratings thereon is illuminated and radiation scattered by the target is imaged onto detectors. A phase difference is then detected between the outputs of the detectors to find the mis-alignment error. In another aspect, an overlay target with gratings or box-in-box structures is illuminated and radiation scattered by the target is imaged onto detectors located away from the specular reflection direction of the illumination in a dark field detection scheme. Medium numerical aperture optics may be employed for collecting the radiation from the overlay target in a bright or dark field configuration so that the system has a larger depth of focus and so that the two structures of the target at different elevations can be measured accurately at the same time. Analytical functions are constructed for the grating type targets. By finding the phase difference between the two gratings at different elevations, misalignment errors can be detected. Analytical functions are constructed as a model for box-in-box type targets where data points away from the edges of the box or bars can be used in the curve fitting. Symmetrical functions are employed to further reduce noise.
Owner:KLA TENCOR CORP

Single-shot magnetic resonance spectroscopic imaging with partial parallel imaging

The present invention has a magnetic resonance spectroscopic imaging (MRSI) method that allows collecting a complete spectroscopic image with one spectral dimension and up to three spatial dimensions in a single signal excitation. The method employs echo-planar spatial-spectral encoding combined with phase encoding interleaved into the echo-planar readout train and partial parallel imaging to reconstruct spatially localized absorption mode spectra. This approach enables flexible tradeoff between gradient and RF encoding to maximize spectral width and spatial resolution. Partial parallel imaging (e.g. SENSE or GRAPPA) is employed with this methodology to accelerate the phase encoding dimension. A preferred implementation is with the recently developed superresolution parallel MRI method, which accelerates along both the readout and phase encoding dimensions and thus enables particularly large spectral width and spatial resolution. The symmetrical k-space trajectory of this methodology is designed to compensate phase errors due to convolution of spatial and spectral encoding. This method is suitable for hyperpolarized MRSI, spatial mapping of the diffusion coefficients of biochemicals and functional MRI using quantitative mapping of water relaxation.
Owner:POSSE STEFAN

Flow cell and system for simultaneous measurement of absorbance and emission in a sample

The flow cell of the present application simultaneously monitors and measures light absorbance and fluorescence of particles in a flowing liquid. The flow cell comprises a housing having a light input face, an absorbance output face and first and second emission output faces; a fluid flow section within the housing that comprises a bottom funnel through which fluid enters the flow cell, a core chamber into which fluid flows from the bottom funnel, and a top funnel into which fluid flows from the core chamber, wherein the bottom and top funnels each comprise a first end which extends at an angle to a second end that is wider in diameter than the first end, and said second end of each is adjacent to and aligned with the core chamber; and a center section within the housing center having a recess formed therein which houses the core chamber of the fluid flow section, wherein said center section comprises a first pair of opposing channels formed in the light input face and the absorbance output face, respectively, and a second pair of opposing channels formed in the first emission output face and the second emission output face and which are perpendicular to the first pair of opposing channels, and wherein the first pair of opposing channels and second pair of opposing channels are in communication with the core chamber. An apparatus comprising the flow cell is also provided.
Owner:BIOCOMP INSTR

Universal Regulatory Apparatus for Controlled Environments for Use with Added Sensors and Analyzers

A gas-based regulatory apparatus has an electrical input, optionally connected to an analog to digital converter; a central processing unit (CPU) comprising a non-volatile memory for storing and retrieving program and configuration data and a random access memory for storing and retrieving other data; a visible alphanumeric display means connected thereto; a user input means adjacent to the display and connected to the processing means; an alarm driven directly or indirectly from the CPU; a pneumatic valve having an input port and an output port, and being driven directly or indirectly from the CPU; and a program that runs on the CPU, for receiving user input, measuring input voltages and pressure voltages from the analog to digital converter, displaying data, converting measured voltages to gas and pressure units, implementing a control algorithm, and driving the pneumatic valve and alarm.
Owner:LIGHTON JOHN R B
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