38results about How to "Maintain physical integrity" patented technology

The present invention provides a gastric retention controlled drug delivery system comprising: (a) a controlled release core comprising a drug, a highly swellable polymer and a gas generating agent, said core being capable of swelling and achieving floatation rapidly while maintaining its physical integrity in gastrointestinal fluids for prolonged periods, and (b) a rapidly releasing coat composition comprising the same drug as in the core and pharmaceutically acceptable excipients, wherein the coating composition surrounds the core such that the system provides a biphasic release of the drug in gastrointestinal fluids.

A utility glove formed of a glove blank of a fabric material in the shape of at least a portion of a hand having one or more areas of elastomeric material injection molded thereon to form one or more three dimensional molded portions, the three dimensional molded portions being the fabric material with the elastomeric material bonded thereto, wherein one or more three dimensional molded portions leave at least one area of fabric material of the glove blank without elastomeric material bonded to the fabric. The fabric material of the glove blank can be made from one or more fabrics, a treated fabric, a coated fabric or combinations thereof, or the fabric may have a portion with a coating on an area without elastomeric material.

The present invention relates to an oral drug delivery system with biphasic release characteristics comprising a porous matrix comprising at least one drug substance, sugar(s), a release retarding polymer, gas generating components and optionally, pharma-ceuti-cally acceptable auxiliary components wherein the pharmaceutical composition further comprises a coating of said drug substance. The pharmaceutical composi-tion, either in the form of pellets (multiparticulate or single unit dosage form), beads, granules, capsules or tablets, is retained in the stomach while selectively delivering the drug(s) at gastrointestinal levels and upper parts of the small intestine over an extended period of time. The release of the drug from the said pharmaceutical composition is characterized by a biphasic release profile of the drug substance, which exhibits both immediate and controlled release characteristics.

A pharmaceutical composition in the form of tablets or capsules provides a combination of temporal and spatial control of drug delivery to a patient for effective therapeutic results. The pharmaceutical composition comprises a drug, a gas generating component, a swelling agent, a viscolyzing agent, and optionally a gel forming polymer. The swelling agent belongs to a class of compounds known as superdisintegrants (e.g., cross-linked polyvinylpyrrolidone or sodium carboxymethylcellulose). The viscolyzing agent initially and the gel forming polymer thereafter form a hydrated gel matrix which entraps the gas, causing the tablet or capsule to be retained in the stomach or upper part of the small intestine (spatial control). At the same time, the hydrated gel matrix creates a tortuous diffusion path for the drug resulting in sustained release of the drug (temporal control). A preferred once daily ciprofloxacin formulation comprises 69.9% profloxacin base, 0.34% sodium alginate, 1.103% xanthan gum, 13.7% sodium bicarbonate, 12.1% cross-linked polyvinylpyrrolidone, and optionally other pharmaceutical xcipients, the formulation being in the form of a coated or uncoated tablet or capsule.

A fire extinguishing device of the explosive type is disclosed for use against conflagrations, wherein the force of detonation of the device is minimized through the use of low density / low mass components; no part of the device having sufficient mass or density to constitute a ballistic hazard, nor be hazardous in concussive shock due to the explosive burst. The present invention is composed of a lightweight casing (3) of frangible material, with a protective exterior sheathing (7). Within the internal cavity of the device, a pyrotechnic detonator (5) is located at or near the center of mass, and is actuated by fuse cord(s) (6) extending from the detonator, the end(s) of which extend(s) from the interior detonator to mounting on the exterior surface. The device is chargeable with a variety of fire-retardant chemical agents (8), including dry powders, two-part reactants, liquid components or others, singly or in combination.

A diffusely reflective optical film includes a blended layer extending from a first to a second zone of the film. The blended layer includes first and second polymer materials separated into distinct first and second phases, respectively. The blended layer may have the same composition and thickness in the first and second zones, but different first and second diffusely reflective characteristics in the first and second zones, respectively. The difference between the first and second diffusely reflective characteristics may not be attributable to any difference in composition or thickness of the layer between the first and second zones. Instead, the difference between the first and second diffusely reflective characteristic may be attributable to a difference in birefringence of the first and / or second polymer materials between the first and second zones. The blend morphology of the blended layer may be substantially the same in the first and second zones.

The present invention provides a gastric retention controlled drug delivery system comprising: (a) a controlled release core comprising a drug, a highly swellable polymer and a gas generating agent, said core being capable of swelling and achieving floatation rapidly while maintaining its physical integrity in gastrointestinal fluids for prolonged periods, and (b) a rapidly releasing coat composition comprising the same drug as in the core and pharmaceutically acceptable excipients, wherein the coating composition surrounds the core such that the system provides a biphasic release of the drug in gastrointestinal fluids.

Electronics mounted on a printed circuit board are housed within a high conductivity case with connecting pins extending therethrough. The case is filled with thermally conductive potting material to provide thermal conduction from the printed circuit board to the case. The case may be a conduit having open ends through which the printed circuit board is inserted or it may comprise a cover mounted to a base plate.

A method for drying traditional Chinese medicine materials in mixing mode through microwave vacuum and hot air comprises placing the traditional Chinese medicine materials in a microwave vacuum drying stove, drying the traditional Chinese medicine materials for 3 to 5 minutes under the condition that the vacuum ranges from 0.07Mpa to 0.09Mpa and the unit microwave power ranges from 3W to 5W, delivering the traditional Chinese medicine materials into a hot air dryer, drying the traditional Chinese medicine materials for 1 to 3 hours under the temperature ranging from 70 DEG C to 90 DEG C, and finally delivering the traditional Chinese medicine materials to the microwave vacuum drying stove again for drying under the condition of the first step till the end. The method adopts mixing of the microwave vacuum drying and the hot air drying, enables the internal structure of the traditional Chinese medicine materials to achieve the effect of swelling, loosening and cracking, improves exudation ratio of decoction of liquid medicine and shortens decoction time without damaging contents of the traditional Chinese medicine materials. Further the method can keep intrinsic body integrity of the traditional Chinese medicine materials, reduces contractibility rate of the traditional Chinese medicine materials, accelerates rehydration of the traditional Chinese medicine materials, improves product quality and reduces energy consumption.

Electronics mounted on a printed circuit board are housed within a high conductivity case with connecting pins extending therethrough. The case is filled with thermally conductive potting material to provide thermal conduction from the printed circuit board to the case. The case may be a conduit having open ends through which the printed circuit board is inserted or it may comprise a cover mounted to a base plate.

The invention discloses a making method of pressed salted duck, which includes: unhairing raw ducks to obtain unhaired ducks; weighing the ducks; vacuum-massaging the ducks and applying dry salt for pressed salted ducks, which accounts for 5.0-8.0% of the weight of the ducks; salting the ducks at -5 DEG C to 1 DEG C for 42-48 hours after massage is performed for 30-50 minutes; cooling herbal extract to 70-75 DEG C; using the herbal extract to hermetically soaking the ducks for 1.5-2.5 hours, using boiled water which is cooled to 48-52 DEG C to clean the ducks; sun-curing the ducks for 24-26 hours; placing the sun-cured ducks into a sun-curing basin and covering with cloth; drying the ducks in the shade in daytime; removing the cloth to air-dry the ducks at night and allowing dew to attachto the ducks; and obtaining the pressed salted duck, wherein making the pressed salted duck takes 6-8 days totally. The pressed salted duck is evenly salted and strong in flavor of cured food, and has dietary health effect.

The invention discloses a making method of kidney-tonifying and qi-tonifying pressed salted duck, which includes unhairing crude ducks to obtain the unhaired ducks, weighing, subjecting the ducks to vacuum massage via dry salt used for pressed salted duck and accounting for 5.0-8.0% of the unhaired ducks, massaging the ducks while applying the dry salt for 30-50 minutes, salting the ducks at the low temperature of -5 DEG C to 1 DEG C for 42-48 hours, cooling herbal extractant to 70-75 DEG C, using the herbal extractant to hermetically soak the ducks for 1.5-2.5 hours, washing the ducks with boiled water cooled to 48-52 DEG C, air-drying the ducks for 24-26 hours, placing the air-dried ducks into a sun-drying basin, covering the ducks with cloth, drying the ducks in the shade without exposure to sunlight in daytime, uncovering the ducks to air-dry the ducks at night, and allowing dew to attach to the ducks to obtain the pressed salted duck, wherein the making method takes 6-8 days totally. The kidney-tonifying and qi-tonifying pressed salted duck is evenly salted, has strong flavor of cured products, and has the dietary therapy and health caring effects of tonifying kidney and qi.

The invention discloses a preparation method of a beauty-nourishing pressed salted duck, comprising the following steps of: unhairing a duck to obtain a bare duck; weighing; carrying out vacuum massage on the duck by the dried salt for the pressed salted duck, wherein the weight of the dried salt is 5.0-8.0% of that of the duck; coating the dried salt for the pressed salted duck when the pressed salted duck is massaged; massaging for 30-50 minutes; curing for 42-48 hours at the low temperature from -5 DEG C to 1 DEG C; cooling the Chinese medicine extracting solution to 70-75 DEG C; soaking the duck for 1.5-2.5 hours in a sealing way by the Chinese medicine extracting solution; cleaning the duck by boiled water with the temperature of 48-52 DEG C, and then drying for 24-26 hours; putting the dried duck into a drying pot, and covering with cloth; drying the duck in the shade without sunshine in the day; and carrying out air drying on the duck by the means that the cloth is opened in the night, so that the dew can be attached to the duck body jointly for 6-8 days to obtain the product. The beauty-nourishing pressed salted duck not only is evenly cured and thick in cured meat, but also has the effect of beauty-nourishing food therapy health care.

The invention discloses a preparing method of kidney-tonifying qi-benefiting seasoned duck. The preparing method comprises the following steps of: frying salt, anise and Sichuan peppercorn according to proportion until the mixture turns yellow, salting the duck and the yellow ingredients at low temperature according to proportion, taking Chinese herbal medicine according to weight part and mixing, adding water, placing for 30-35 minutes at normal temperature, adding water again, boiling to obtain traditional Chinese medicine extracting solution, placing in soaking equipment, placing the treated duck, soaking and drying, stirring thick broad-bean sauce, soy and water according to proportion for blending sauce, carrying out vacuum massage on the dried duck while applying the sauce, and drying 2-3 hours in a drying room after massaging for 30-50 minutes, thus obtaining a finished product. The kidney-tonifying qi-benefiting seasoned duck prepared by the invention is uniform in salting and good in mouth feeling and has a kidney-tonifying qi-benefiting dietary-therapy health-care function.

A non-effervescent, solid dosage form containing mirtazapine, which is used to form mirtazapine pharmaceutical tablets. The dosage form contains mirtazapine, a hydrophilic component, and at least one lubricant. In some embodiments, the dosage forms contain a salivating agent. Processes for producing mirtazapine orally disintegrating tablets are also provided.

The present invention relates to a flowable bone graft material including an inorganic composition comprising calcium phosphate having a particle size of about 100 μm to about 1,000 μm, bioactive glass, and one or more biocompatible polymers comprising carboxymethyl cellulose and a fluid.

The present invention relates to an apparatus for the removal and containment of human waste products from the effected area of incontinent patients. The apparatus and process encapsulates the areas of the body where urine and fecal matter are excreted. In particular, the present invention is directed to an apparatus for the containment and removal of human waste products, comprising: a receptacle; a vacuum connection to apply force for attaching the receptacle to the patient; and a vacuum dispersion membrane to provide mechanical support to the skin so as to minimize tensile force applied to the skin.

Improved treatment blocks useful in the treatment of lavatory appliances, particularly toilets are provided. The improved treatment blocks are solid block compositions which provide an extended service life, particularly when used in an ITB device. Methods of producing the solid block composition and treatment blocks therefrom, as well as methods of use are also disclosed.

A non-effervescent, solid dosage form containing mirtazapine, which is used to form mirtazapine pharmaceutical tablets. The dosage form contains mirtazapine, a hydrophilic component, and at least one lubricant. In some embodiments, the dosage forms contain a salivating agent. Processes for producing mirtazapine orally disintegrating tablets are also provided.

A method is provided for preparing a semiconductor wafer for testing. The method includes selecting a die to be tested; measuring a diagonal of the die; thinning an area over the die extending beyond the scribe lines, the thinned area may be a circular area having a diameter that is larger than the measured diagonal; providing an insert inside the thinned area; and providing an adhesive on the peripheral area of the insert so as not to obscure the optical path to the die. The insert is advantageously made of an undoped silicon.

The ice cream packaging of the present invention is a laminate thermal packaging capable of retaining cooler temperatures within the packaging for an extended period of time. Use of the packaging of the present invention, permits the ice cream to retain better physical, chemical and organoleptic properties. The packaging comprises layers of olefins, such as a polypropylene including a bi axially oriented polypropylene. One of the layers comprises a metallized bi axially oriented polypropylene containing aluminum. The present invention also provides a method of vending ice cream using the packaging of the present invention.

The invention discloses a preparation method of a seasoned duck, comprising the following steps of: frying salt, anise and pepper to be yellow according to proportions; curing the duck and the ingredients which are fried to be yellow at low temperature according to proportions; taking Chinese medicinal herbs according to parts by weight and evenly mixing; adding water, and then standing for 30-35minutes at normal temperature; adding water again, and stewing to obtain a Chinese medicine extracting solution; putting into soaking equipment; putting the cleaned duck; drying after soaking; stirring thick broad-bean sauce, soy sauce and water according to proportions to prepare the sauce; carrying out vacuum massage on the dried duck; coating the sauce when the duck is massaged; and massaging for 30-50 minutes, and then drying for 2-3 hours in a drying room to obtain a finished product. The seasoned duck not only is evenly cured and good in mouth feel, but also has the effect of health care.

A method is provided for preparing a semiconductor wafer for testing. The method includes selecting a die to be tested; measuring a diagonal of the die; thinning an area over the die extending beyond the scribe lines, the thinned area may be a circular area having a diameter that is larger than the measured diagonal; providing an insert inside the thinned area; and providing an adhesive on the peripheral area of the insert so as not to obscure the optical path to the die. The insert is advantageously made of an undoped silicon.

The present invention relates to an apparatus for the removal and containment of human waste products from the effected area of incontinent patients. The apparatus and process encapsulates the areas of the body where urine and fecal matter are excreted. In particular, the present invention is directed to an apparatus for the containment and removal of human waste products, comprising: a receptacle; a vacuum connection to apply force for attaching the receptacle to the patient; and a vacuum dispersion membrane to provide mechanical support to the skin so as to minimize tensile force applied to the skin.

Improved treatment blocks useful in the treatment of lavatory appliances, particularly toilets are provided. The improved treatment blocks are solid block compositions which comprise at least one detersive surfactant, a hydrocarbon solvent constituent, and one or more further optional constituents, including bleach constituents. The improved treatment blocks provide improved processing and handling characteristics. Methods of producing the solid block composition and treatment blocks therefrom, as well as methods of use are also disclosed.

A additive delivery system and method which includes a additive gel, a filter and a fluid / gel chemistry exchange region, wherein the exchange region subjects the additive gel to different types or combinations of contact with the fluid in order to control the additive release rate, maintain a uniform release rate, maintain the physical integrity of the gel or combinations thereof.