49results about How to "Improve safety and effectiveness" patented technology

An enteral administration assembly for administering fluids through an enteral device. The administration assembly comprising an inlet, an outlet, and a valve mechanism between the inlet and outlet. The inlet is configured to interlock with only an enteral device to form a sealed connection allowing the passage of fluid between the enteral device and the inlet. The assembly may include a valve or turbulating mechanism comprising a valve and at least one turbulator adapted to change the direction of fluid flowing through the assembly to prevent clogging and flocculation of administered substances.

A probe system for measuring fluid flow in a conduit, such as a blood vessel with ultrasound transit time or similar measurement methods. The probe system having a probe body with a space to receive in a secure but detachable fashion a pliable soft insert. The insert has a central lumen or aperture which is sized to securely but detachably fit around a vessel or conduit without squeezing or in any way altering the conduit during application or use. The insert is acoustically matched with the vessel or conduit and fluid flowing therein to thereby minimize distortion or attenuation of ultra sound waves generated to assess flow. In a further aspect a set of inserts with varying sized lumens or apertures are provided to match with vessels or conduits of varying size. The system among other things increases accuracy of flow measurements while minimizing trauma to the vessel or conduit.

The present invention relates to medicine composition of aescin and its preparation process and use. The aescin with purity over 90 % may be compounded with medicine carrier to form medicine composition with high synergistic effect, obviously reduced irritation on blood vessel and muscle, obviously raised medicinal effects of resisting inflammation, resisting exudation, improving blood circulation, etc. The medicine composition has low irritation, high safety, high therapeutic index and other features.

This invention is directed to medical equipment and can be used for elevation of resistance of a human body against various pathologies including bronchial asthma, hyperplastic anemia and iron deficiency anemia, neurocirculatory dystonia, hypertension, obesity. This instrument can also be useful for treatment and prevention of respiratory and metabolic dysfunctions, for enhancement of non-specific compensatory capabilities of a human body and its aerobic output, as well as for improving physical fitness and regenerative ability of athletes, and reducing negative side effects of ionizing radiation.

The invention discloses a self-service storage system which comprises an entrance guard, a storage space and a storage cabinet inside the storage space.The entrance guard controls a switch of an entrance of the storage system.A two-dimensional read head device is arranged in the entrance guard.A cabinet position lock is arranged on the storage cabinet for controlling opening and closing of the storage cabinet.The self-service storage system is characterized by further comprising a control system; the control system comprises a storage intelligent gateway, a remote server and a control terminal for controlling the cabinet position lock; the two-dimensional read head device is connected and communicated with the storage intelligent gateway through an RS-485 bus, the storage intelligent gateway and the remote server are connected and communicated through an RJ45 cable or a 3G / 4G network, and the storage intelligent gateway and the control terminal are connected and communicated through an RS-485 bus.The self-service intelligent storage system based on two-dimensional codes is provided for overcoming the defects that existing public self-service storage is low in safety performance, system management and system updating encryption are difficult, and an IC card and a key are not convenient to use.

The invention discloses a citicoline sodium glucose injecta and a preparation process thereof. The citicoline sodium glucose injecta mainly contains the active ingredients: citicoline sodium, isotonic agent glucose, a stabilizer, a pH regulator and water for injection, wherein the stabilizer is selected from one or two of malic acid, sale compounds thereof and sulfite compounds; the pH regulator is one or more of sodium hydroxide, hydrochloric acid, malic acid and apple sodium; the weight ratio of the active ingredients of the Citicoline sodium to the isotonic agent glucose is 1:(20-100), theweight ratio of the active ingredients of the citicoline sodium to the stabilizer is 1:(0.02-2), and the stabilizer is added to solve the problem of unstable heating and excessive related substances of the injecta in the production and storage process and improve the quality stability and the safe validation of medicaments.

The invention provides a terminal information acquisition method and device. The method comprises steps that if the device information of an SIM card binding terminal changes, the association information of an SIM card is acquired according to an identity identifier of the SIM card; the association information is synchronized to a present binding terminal of the SIM card. The method is advantagedin that when the device information of the SIM card binding terminal changes, for example, the SIM card is transferred to a new terminal, or the present binding terminal of the SIM card performs factory reset operation, the present binding terminal of the SIM card has not any of the relevant information of the SIM card, the association information of the SIM card can be automatically acquired by the present binding terminal of the SIM card according to the identity identifier of the SIM card, and the association information is locally synchronized. Compared with the prior art, the informationis acquired without manual operation of a user, the intelligent degree of the user terminal is improved.

The invention relates to a medical bag which is intended for the infusion of a medicament by means of gravity. The inventive bag comprises: at least two compartments, namely a first compartment (1) containing a medicament in the form of a solution and a second compartment (2) containing a rinsing solution; and means for separating / communicating the compartments, which prevent the rinsing solution from automatically entering the medicament compartment except at the end of the infusion period. The rinsing solution ends the infusion, by rinsing the medicament bag and the infusion line, such as to prevent any risk of contamination or leakage of residual medicament from the bag or line.

The invention discloses a coupled river water quality and sediment health monitoring system and method. The coupled river water quality and sediment health monitoring system comprises an unmanned ship, a data transmission center and a terminal user application platform, wherein river sediment deposition on-line monitoring equipment, a river water quality on-line monitoring module and river water quality sampling equipment are carried on the unmanned ship, topographic data and part of water quality health index data at a measurement point are collected in real time, and the measurement data istransmitted to the terminal user application platform through the data transmission center; the data transmission center comprises a satellite system and a satellite system network management center,and is used for navigating the unmanned ship according to the physical coordinates of each measurement point provided by the terminal user application platform and transmitting the measurement data tothe terminal user application platform; and the terminal user application platform is used for determining the number of measurement points and the physical coordinates of each measurement point according to the known width and length of a river, and providing the measurement data collected in time by the unmanned ship and the measurement data obtained by analysis to the unmanned ship through thedata transmission module to perform early warning prompt.

The invention relates to a radio frequency ablation catheter and system. The radiofrequency ablation catheter comprises an ablation catheter body with an ablation coil, the ablation catheter body comprises a catheter body, and the catheter body sequentially comprises a guide wire tube, a main body tube, a coil sleeve, a coil and an insulating outer sleeve from inside to outside; and the guide wire tube is arranged in the catheter body, the main body tube and the guide wire tube are bonded at the far end to form a hemispherical smooth end part, the coil sleeve sleeves the main body tube, the insulating outer sleeve is thermally shrunk outside the coil, and sealing sleeves are further arranged and thermally shrunk at two ends of the insulating outer sleeve. A gap for placing a thermocouple is formed in the coil formed by winding an ablation line. The catheter structure has high sealing safety, and the temperature measurement accuracy is remarkably improved. In addition, the coil is arranged to be multiple sections, each section of coil is provided with at least one thermocouple used for segmented temperature control, and the temperature control accuracy and the radiofrequency ablation efficiency are improved. The invention also provides a wiring mode of a plurality of coils, so that the product is safe and effective.

The invention discloses a full-closed auxiliary frame for energy-saving building doors and windows, which comprises brackets and auxiliary frame boards. The auxiliary frame boards are connected to form a full-closed auxiliary frame through the brackets, a communication groove is arranged on the inner lateral side of the full-closed auxiliary frame, auxiliary frame mounting fasteners are fittingly arranged in the communication groove and fixedly connected with door-window mounting fasteners, and the door-window mounting fasteners are connected with building door-window section. The full-closed auxiliary frame for doors and windows is simple in structure and capable of fully closing mounting openings of building doors and windows, and has the advantages of heat insulation, environment protection, energy conservation, cost economization and convenience in mounting. Traditional door-window mounting process is changed, brand new building doors and windows with no pollution can be delivered to users, the problem of integration of wall heat insulation and full closing of door-window mounting openings of current buildings is thoroughly solved, and the problems of water permeation and construction linkage contradiction of door-window mounting and civil engineering openings are thoroughly solved. The problem of 'cold bridge' of energy-saving building doors and windows can be solved while mounting period of doors and windows can be shortened greatly, the full-closed auxiliary frame is fireproofing and flame-retardant, and safety effectiveness can be improved.

Embodiments of the present invention provide an invoice issuance system and method. The system comprises a self-service invoicing terminal, an enterprise server and an enterprise tax control device. The self-service invoicing terminal is used for transmitting an obtained identification code for voice issuing of a user to the enterprise server; the enterprise server comprises a purchasing flow information acquisition module which is used for obtaining purchasing flow information of the user according to the identification and a preset identification protocol, and an invoice base data generation module which is used for generating invoice base data according to the purchasing flow information; the enterprise tax control device is used for generating invoice real data according to the invoice base data and the preset algorithm; and the self-service invoicing terminal is further used for printing the invoice real data into a paper invoice. According to the system and method provided by the embodiments of the present invention, for enterprise users, various cost overheads of enterprise invoice management are reduced, and enterprise operation efficiency is improved; and for consumers, through a good way of human-computer interaction, the invoice issuance process of the user is reduced, and the time and the effort are saved.

The invention relates to the field of traditional Chinese medicines, and relates to a pharmaceutical composition for treating malignant tumor, a preparation method and an application. The pharmaceutical composition is prepared by radix scrophulariae, rhizoma curcumae, fritillary bulb, roasted rhizoma atractylodis macrocephalae, raw oyster shell and vinegar turtle. The pharmaceutical composition has the functions of softening hard lumps and dispelling nodes, strengthening body resistance and resisting cancer. In-vivo and in-vitro experimental results show that the pharmaceutical composition has significant effect for inhibiting the cancer, has good stability and small toxic and side effects, and has good treating effects for a plurality of malignant tumors such as stomach cancer, lung cancer, esophageal cancer, liver cancer, cervical cancer and breast cancer. The preparation method of the pharmaceutical composition is simple; and the pharmaceutical composition is high in safety and efficiency, low in cost and wide in clinical applications.

A tendo calcaneus suturing instrument, comprising: a first support and a second support that are of a U-shaped structure, a distance adjustment device, a first guide sleeve, a second guide sleeve, a first positioning tube, a second positioning tube and a tendo sheath cutter. An outer arm and an inner arm of the first support, and an outer arm and an inner arm of the second support are respectively provided with a first positioning hole, a first guide hole, a second positioning hole and a second guide hole; and the first guide sleeve / the second guide sleeve is fixed by means of the first positioning hole / the second positioning hole and is matched with the first guide hole / the second guide hole. The first positioning tube / the second positioning tube provided with a through hole is arranged in the first guide sleeve / the second positioning sleeve or the tendo sheath cutter is arranged in the first guide sleeve and / or the second guide sleeve in a matching manner. The tendo calcaneus suturing instrument can simplify the surgical procedure, improve the surgical effect and relieve pains of a patient.

The invention relates to a medical bag which is intended for the infusion of a medicament by means of gravity. The inventive bag comprises: at least two compartments, namely a first compartment (1) containing a medicament in the form of a solution and a second compartment (2) containing a rinsing solution; and means for separating / communicating the compartments, which prevent the rinsing solution from automatically entering the medicament compartment except at the end of the infusion period. The rinsing solution ends the infusion, by rinsing the medicament bag and the infusion line, such as to prevent any risk of contamination or leakage of residual medicament from the bag or line.

[Problem] To provide a useful dipeptide-containing composition derived from dried bonito flakes and the like, having an angiotensin-converting-enzyme inhibiting activity that imparts a blood pressure reducing function. [Solution] A composition containing a dipeptide derived from a fish meat protein having an angiotensin-converting-enzyme inhibiting activity. The composition is characterised by containing: at least one type of dipeptide selected from the group consisting of a dipeptide consisting of a tryptophan-leucine amino acid sequence, a dipeptide consisting of a leucine-tryptophan amino acid sequence, a dipeptide consisting of a tryptophan-isoleucine amino acid sequence, a dipeptide consisting of a valine-triptophan sequence, a dipeptide consisting of a tryptophan-tyrosine sequence, a dipeptide consisting of a tryptophan-methonine sequence, a dipeptide consisting of a serin-triptophan sequence, and a dipeptide consisting of an asparagine-triptophan sequence; and / or an acid addition salt of said dipeptide(s).

The invention relates to a high-speed train brake disc-a wheel disc. The high-speed train brake disc is composed of a brake disc body, a brake friction surface, a central positioning hole, uniformly-distributed mounting holes, a reinforcing boss, radial radiating ribs and a transition balancing boss; and the brake disc is characterized in that the central positioning hole of the high-speed train brake disc body is positioned on a high-speed train wheel, the central positioning hole and the high-speed train wheel are connected by bolts through the uniformly-distributed mounting holes, and the uniformly-distributed mounting holes are distributed on the reinforcing boss. Heat generated in the braking friction process is dispersed through the radial radiating ribs, and the generated vibrationis eliminated through the transition balancing boss; and the brake disc has the advantages of being good in heat dissipation effect, high in braking strength, stable in braking operation and high in safety and effectiveness.

The invention discloses a medical impact hammer, and belongs to the field of experiment measuring techniques and the field of medical apparatuses. The medical impact hammer comprises an electromagnetic power hammer, a guide sleeve, an electromagnetic coil, a housing, a spring, a handle, an osteotome adapter, a controller, a gear switch and a start-up button, wherein the start-up button is mountedat the position of a thumb, on the handle; the gear switch is mounted at a position adjacent to the housing, of the handle, and comprises three gears including a strong gear, a medium gear and a weakgear; an electromagnetic power hammer body is a cylinder; and a head hitting location is a hemispheroid, and cooperates with the guide sleeve through an air gap. The medical impact hammer disclosed bythe invention adopts an electromagnetic force compression spring for energy storage; and when the electromagnetic force is released, the electromagnetic power hammer is pushed by the spring to implement beating on an osteotome, artificial factors are eliminated, and the controllability and the stability of the knocking force are improved. An impact hammer which cooperates with the osteotome workfor usage and of which the impact force is stable and controllable is provided for surgeries in orthopaedics and dentistry including sinus lift and the like, so that the safety and the validity of theusing of the osteotome in the surgeries are improved, the surgery efficiency is improved, and the medical care risk is reduced.

An enteral administration assembly for administering fluids through an enteral device. The administration assembly comprising an inlet, an outlet, and a valve mechanism between the inlet and outlet. The inlet is configured to interlock with only an enteral device to form a sealed connection allowing the passage of fluid between the enteral device and the inlet. The assembly may include a valve or turbulating mechanism comprising a valve and at least one turbulator adapted to change the direction of fluid flowing through the assembly to prevent clogging and flocculation of administered substances.

The invention relates to a connecting structure which is used for connecting parts with different thermal expansion coefficients. The connecting structure comprises a first part, a second part, a sliding block and an axial connecting piece, wherein the thermal expansion coefficients of the first part and the second part are different; the sliding block comprises an inclined surface and is slidablyarranged between the first part and the second part; the first part is provided with multiple guide slots; the inclined surface is in tight contact with the side surfaces of the guide slots; the axial connecting piece is used for connecting the first part, the sliding block and the second part; a dip angle of the inclined surface is larger than a friction angle; and when the connecting structureis heated, the guide slots and the sliding block slide relatively, so that the component of the thermal expansion sliding amount of the sliding block in the axial direction is equal to the thermal deformation amount of the axial connecting piece. Correspondingly, the invention provides an exhaust system of an aero-engine comprising the connecting structure. The exhaust system of the aero-engine comprising the connecting structure has the advantages of stable structure, reliability and the like.

The invention discloses a toad venom extract and a preparation method thereof. The preparation method comprises the following steps: (1) the toad venom medicinal material is added with absolute ethyl alcohol for reflux extraction; (2) the extracting solution obtained is condensed, separated by a silica gel column, and eluted by petroleum ether and acetone at the volume ratio of 3-10: 1 in an isocratic manner, the eluent is collected, filtered, and evaporated to be dry, thus obtaining the toad venom extract with three bufogenin mixtures. The preparation method of the invention has the advantages of being simple and convenient, being easy to operate, and being suitable for industrialized production; the content of the three bufogenin mixtures in the toad venom extract of the invention is not less than 90%.

The invention provides an SARS CoV-2 single-epitope T cell antigen peptide, a pluripotent T cell epitope peptide prepared from the antigen peptide, and a DC cell loaded with the pluripotent T cell epitope peptide; T cell immunity of an MHC-I pathway in vivo can be induced, and the immune function of an organism is reconstructed; and the antiviral function of autologous CD8 <+> CTL is stimulated, amore effective and safer means is provided for prevention and / or treatment of coronavirus infection related diseases, and wide clinical application and popularization prospects are achieved.

The invention relates to a high-dimensional data encryption method and system, and the method comprises the steps: S1, enabling the production data of each product to be packaged in a high-dimensionaldata encryption code during commodity production, and forming a code for each object; S2, forming a track data chain by data of the product in production and each circulation link, and encrypting thetrack data chain to form an encrypted data chain; and S3, storing the encrypted data chain into a plurality of nodes of a distributed server. A distributed high-dimensional tracing encrypted storagesystem is constructed through a tracing code encryption engine, a double-helix block chain distributed storage bottom layer framework, a data transmission pipeline and a big data processing pipeline.

The invention discloses a citicoline sodium glucose injecta and a preparation process thereof. The citicoline sodium glucose injecta mainly contains the active ingredients: citicoline sodium, isotonic agent glucose, a stabilizer, a pH regulator and water for injection, wherein the stabilizer is selected from one or two of malic acid, sale compounds thereof and sulfite compounds; the pH regulator is one or more of sodium hydroxide, hydrochloric acid, malic acid and apple sodium; the weight ratio of the active ingredients of the Citicoline sodium to the isotonic agent glucose is 1:(20-100), theweight ratio of the active ingredients of the citicoline sodium to the stabilizer is 1:(0.02-2), and the stabilizer is added to solve the problem of unstable heating and excessive related substances of the injecta in the production and storage process and improve the quality stability and the safe validation of medicaments.

The invention relates to an occluder, comprising a first disc-shaped structure with grids, the first disc-shaped structure is braided by at least two sets of braided wires, the two sets of braided wires are crossed to form multiple cross points, and the first disc-shaped structure is A choke film is also arranged in the structure, and the edge of the choke film is connected with the intersection of the outermost circle of the intersections of the multiple circles by a suture, and the number of intersections sutured with the choke film in the intersection of the outermost circle is less than the number of the intersection points of the outermost circle. The number of all intersections in the intersection of the outer circle, and the position of the blocking membrane close to its edge is connected with a circle of intersections in the intersection of the outermost circle among the intersections of multiple circles by sutures. The invention can reduce the possibility of occurrence of the phenomenon that the edge of the blocking film cannot reach the edge of the disk surface of the occluder, thereby improving the blocking effect of the occluder.

The invention discloses application of tirofiban in preparation of a medicine for treating human respiratory syncytial virus infection, and relates to the technical field of virus infection resistance. The invention provides favorable drug support for clinically treating human respiratory syncytial virus infection, enriches the drug types of clinical drugs for intervening human respiratory syncytial virus infection, and broadens the antiviral types of tirofiban. In addition, tirofiban as a clinical medicine has good safety and effectiveness, so that the inventor has a good safe medication basis when tirofiban is used for treating human respiratory syncytial virus infection. The invention lays a foundation for further developing medicines with antithrombotic ability into anti-infective medicines. The invention fills the blank of medicines for treating human respiratory syncytial virus, especially pediatric medicines, and has great social value.

The invention provides a power grid data processing method and device, electronic equipment and a storage medium, and the method comprises the steps: receiving electric quantity data uploaded by target users through pseudonyms, wherein each target user is provided with a plurality of pseudonyms; verifying the authenticity of each pseudonym; after the authenticity verification, verifying the validity of each pseudonym; and under the condition that the validity verification is passed, obtaining the electric quantity data of the target user bound with each pseudonym. According to the scheme, the problem that the user identity and the user data in the smart power grid cannot be powerfully protected at the same time at present is solved, and the technical effect of effectively protecting the user privacy in the power grid data is achieved.

The invention provides an ivabradine hydrochloride single-layer osmotic pump controlled release tablet and a preparation method thereof. The single-layer osmotic pump controlled release tablet comprises three parts, namely a tablet core, a semipermeable coating film and a drug release pore, wherein the tablet core comprises the following components in percentage by weight: 5-30% of ivabradine hydrochloride, 0-60% of a suspending agent, 30-90% of a penetration enhancer and 0.1-3% of a lubricant; the semipermeable coating film comprises the following components in percentage by weight: 80-99% of a semipermeable film forming material and 1-20% of a pore-foaming agent; the weight gain of the coating is 3-15% of the weight of the tablet core; and the pore diameter of the drug release pore is 0.4-1.2mm. The ivabradine hydrochloride single-layer osmotic pump controlled release tablet is orally taken once a day, is stable in blood concentration and is not easily influenced by gastrointestinal tract environments.