The invention provides a blood sugar lowering selenium-rich cyclocarya paliurus drink, which is characterized by being prepared from the following substances by weight: 40-60 parts of cyclocarya paliurus leaf, 5-15 parts of Malus hupehensis fruit, 5-15 parts of crataegus pinnatifida, 5-15 parts of Chaenomeles sinensis, 3-8 parts of Indocalamus latifolius leaf, 3-8 parts of mint leaf, 3-8 parts of selenium-containing 0.1% semen raphani, 3-8 parts of panax notoginseng, and 3-8 parts of Lonicera japonica. The preparation method consists of: weighing raw materials according to needs, conducting mixing and crushing, then adding purified water to perform infiltration, carrying out freezing and natural thawing, adding purified water after complete thawing, performing stirring extraction at 60-90DEG C for 5-12h; and concentrating the filtrate, then conducting spray drying, and carrying out subpackaging or tabletting according to the standard of 0.5-1g per part. The cyclocarya paliurus drink provided by the invention has the beneficial technical effects that: (1) the drink adopts pure natural food and medicine and edible plant resources, the processing technology is green, and the drink is not added with any chemical raw material, essence or preservative, and has no toxic or side effect; and (2) the drink has the effects of lowering blood sugar, regulating blood lipid and promoting islet functions.