33results about How to "Improve islet function" patented technology

The invention relates to a milk powder with a function of treating diabetes and a preparation method thereof. The preparation method comprises the following steps of: weighing finger citron, mulberry, Chinese wolfberry, Chinese yam, kudzu root, ophiopogon root, pseudostellaria root and coix seed in parts by weight, mixing the component materials, adding water for decocting, filtering and concentrating to obtain extract, evenly mixing the extract with fresh milk in a ratio of 1:(20-50) in parts by weight, and then preparing milk powder by the existing conventional milk powder preparation process; or mixing the component materials, adding 70% ethanol for reflux extraction, concentrating to obtain extract with the density of 1.23-1.26g / cm<3>, evenly mixing the extract with fresh milk in a ratio of 1:(20-50) in parts by weight, and then preparing milk powder by the existing conventional milk powder preparation process.

The invention relates to flour with a function of treating diabetes and a preparation method thereof. The preparation method comprises the following steps of: 1, weighing the following components in part by weight: 10 to 13 parts of medlar, 12 to 15 parts of mulberry fruit, 20 to 25 parts of finger citron, 15 to 18 parts of cinnamomvine, 5 to 10 parts of common macrocarpium fruit, 5 to 10 parts of dwarf lilyturf tuber, 14 to 17 parts of siberian solomonseal rhizome and 10 to 12 parts of parslane herb; 2, mixing the components, adding water and decocting the mixture in water twice, wherein at the first time, water in an amount which is 10 times that of the mixture is added to decoct the mixture for 2 hours, and at the second time, the water in an amount which is 8 times that of the mixture is added to decoct the mixture for 1.5 hours; filtering decoction extract obtained at two times with a 160 to 180-mesh sieve, and concentrating filter liquor until the density is between 1.23 and 1.26 g / cm<3> to obtain extractum; drying the extractum under vacuum, crushing, and sieving with an 80 to 100-mesh sieve to obtain fine powder; and mixing the fine powder and flour uniformly according to weight ratio of 1:(7-10) to obtain the flour. The flour can nourish pancreas islet cells, improve pancreas islet function, reduce fasting and postprandial blood sugar and improve the living quality of patients who suffer from the diabetes.

The invention discloses a pharmaceutical composition, a preparation method and applications thereof. The pharmaceutical composition is composed of following raw material in parts by weight: 10 to 30 parts of rhizome of common yam, 10 to 30 parts of muscardine silkworm, 3 to 15 parts of silkworm chrysalis, 3 to 20 parts of radix astragali, 4 to 20 parts of anemarrhena, 3 to 15 parts of dayflower, 10 to 35 parts of white peony root, 10 to 35 parts of polyghace seche and 10 to 35 parts of Chinese magnoliavine. The pharmaceutical composition has a stable quality and a definite effect on preventing and curing diabetes, no side or toxic effects, and no strict usage limitation, is user-friendly, and can be used for a long time.

The invention discloses a diabetes functional beverage gamma balance liquid, belongs to the technical field of food adjunctive therapy, and specifically relates to a functional ecology beverage with significant effects of control of blood glucose and improvement of diabetic complications. The present invention provides a beverage with characteristics of nourishing and relieving by the food, effective control of blood glucose fluctuation, and improvement of symptom complex. According to the present invention, the beverage of the present invention can match the drug treatment, such that the useamount of the drug can be gradually reduced, the side effect can be reduced, the body immunity can be improved, and the symptom complex of the diabetes can be improved; 3000 ml of the diabetes functional beverage of the present invention is prepared by the following components, wherein the components comprise: 200-300 mg of gamma-amino butyric acid (food-grade powder), 3-5 g of ginseng, 5-10 g ofobtuseleaf senna seed, 3-5 g of ganoderma lucidum, 5-10 g of mulberry, 3-5 g of corn stigma, 10-15 g of black bean and the balance of water.

The invention provides a blood sugar lowering selenium-rich cyclocarya paliurus drink, which is characterized by being prepared from the following substances by weight: 40-60 parts of cyclocarya paliurus leaf, 5-15 parts of Malus hupehensis fruit, 5-15 parts of crataegus pinnatifida, 5-15 parts of Chaenomeles sinensis, 3-8 parts of Indocalamus latifolius leaf, 3-8 parts of mint leaf, 3-8 parts of selenium-containing 0.1% semen raphani, 3-8 parts of panax notoginseng, and 3-8 parts of Lonicera japonica. The preparation method consists of: weighing raw materials according to needs, conducting mixing and crushing, then adding purified water to perform infiltration, carrying out freezing and natural thawing, adding purified water after complete thawing, performing stirring extraction at 60-90DEG C for 5-12h; and concentrating the filtrate, then conducting spray drying, and carrying out subpackaging or tabletting according to the standard of 0.5-1g per part. The cyclocarya paliurus drink provided by the invention has the beneficial technical effects that: (1) the drink adopts pure natural food and medicine and edible plant resources, the processing technology is green, and the drink is not added with any chemical raw material, essence or preservative, and has no toxic or side effect; and (2) the drink has the effects of lowering blood sugar, regulating blood lipid and promoting islet functions.

The invention relates to structures and application of a bifunctional protein and a derivative of the bifunctional protein and belongs to the technical field of biological engineering. The technology of computer aided molecular design is adopted and the means of joint engineering are combined to design and prepare a recombinant protein with double functions of reducing blood sugar and blood fat; and on this basis, the obtained target recombinant protein is subjected to polyethylene glycol chemical modification. The target recombinant protein and a chemically modified derivative thereof have obvious blood sugar and blood fat reducing activities for mice models with diabetes. The molecule of the protein can be used for treating diabetes and concurrent diseases of diabetes.

The invention relates to powder capable of restoring the function of the pancreatic islet and the preparation method thereof. The powder is made by adopting the following steps that mulberry fruit, Fructus Lycii, Fructus Citri Sarcodactylis, Poria, pumpkin, Semen Coicis, Radix Puerariae, Fructus Citri, Radix Ginseng and Radix Astragali are weighed according to the parts by weight; the above component materials are mixed and decocted in water twice, wherein 10 weight times of water is added for the first time and the decoction time is 2 hours, and 8 weight times of water is added for the second time and the decoction time is 1.5 hours; the solution extracted from twice decoctions is filtered through a 160 to 180 mesh sieve respectively, and filtrate is concentrated until the density ranges from 1.23 g / cm3 to 1.26 g / cm3 to produce extract; the extract is vacuumized, pulverized and sieved through a 80 to 100 mesh sieve to produce fine powder; the fine powder is uniformly mixed with cooked millet powder and cooked sesame seed according to the weight fraction mixture ratio of 1:3 to 6:0.5 to 1, and the powder is obtained. By adopting the powder, nutrients can be supplied to the islet cells, the function of the pancreatic islet is improved, the glycemic indexes of foods can be effectively controlled, the fasting blood glucose level and the postprandial blood glucose level are lowered, the dosage of antidiabetic drugs is reduced, and the life quality is improved.

The invention provides a polypeptide. The polypeptide solves the problem that the existing polypeptide for promoting islet neogenesis has a short plasma half-life and low activity. The invention also discloses a derivative of the polypeptide, a medicinal salt of the polypeptide and a pharmaceutical composition. The polypeptide has high stability in blood and a long half life.

The invention relates to polypeptide, a polypeptide vaccine and application thereof. An amino acid sequence of the polypeptide is an amino acid sequence shown as SEQ ID NO.1. The polypeptide and the vaccine which are disclosed by the invention not only keep immunogenicity of a full-length IL-1beta protein, but also avoid or reduce acute toxicity possibly caused by the full-length IL-1beta protein to the greatest degree, have a small side effect, and have wide application prospect in the aspect of disease treatment related to inflammation of type II dibetes and the like.