The invention relates to a production method of compound wine for beauty, freckle removal, chest enlarging and heat clearing of female. The production method comprises the steps of crushing medicinal materials such as red dates, a pawpaw, fructus lycii, radix polygonati officinalis, rhizoma anemarrhenae, cape jasmine, fructus forsythiae and semen cassiae into granules with 40-mesh fineness respectively, adding an appropriate amount of water at a certain weight ratio, mixing, placing the granules in an extraction kettle of a supercritical carbon dioxide extractor, extracting active ingredients of traditional Chinese medicine, putting extraction liquid in brewed white wine (with the alcoholic strength of 27-38%vol), sufficiently soaking, dissolving for 30-40d, filtering, encapsulating, and obtaining the finished compound wine. According to the production method, the unique formula can clear heat, can purge fire, improves constipation, treats fire excess from yin deficiency, dizziness, a headache and sleeping instability, quickly fades chloasma, butterfly freckles and the like which are caused by qi and blood stasis, viscus unbalance, ultraviolet radiation and environmental pollution, effectively improves insomnia and dreaminess due to mind malnutrition or malaise, can improve estrogen balance, and quickly removes the freckles and enlarges a chest from a source.