The invention relates to a regional integrated energy system optimization scheduling method for fuel characteristics of a plug-in hybrid electric vehicle, which is characterized in that a main power system and a slave power system of a power system of the plug-in hybrid electric vehicle are considered at the same time, in the main power system, a battery pack stores electric energy under the action of a charging device, and in the slave power system, the main power system stores the electric energy; electric energy is transmitted to a motor to be utilized, and in the slave power system, an engine utilizes chemical energy of gasoline in an oil tank; the power consumption characteristics and the fuel oil characteristics of the two sets of power systems cooperate with each other, so that the driving rule of the vehicle is more flexibly changed, and the charging load of the vehicle is dispatched; fuel oil characteristics of the plug-in hybrid electric vehicle are considered in a regional integrated energy system, benefits and requirements of the integrated energy system and a new energy vehicle user are considered, the utilization rate of integrated energy and the consumption rate of renewable energy are improved, load fluctuation is reduced, and the power supply reliability of the system is enhanced.