37results about How to "Antitumor activity" patented technology

The invention discloses panax japonicus polysaccharide.The main chain structure thereof is Beta-D-1 to 3-mannan and / or Alpha-D-3 to 4-mannan and heterosaccharide containing galactan, xylan and glucan, the weight-average molecular weight of the panax japonicus polysaccharide is 5,000 to 2,000,000, the intrinsic viscosity at 25 DEG C is 1 to 100ml / g, and the mole ratio of the three elements of C: H: O is 1: 2: 1. The preparation of the panax japonicus polysaccharide comprises the following steps: after being dried, smashed and skimmed, the panax japonicus is soaked by water under the normal temperature and is stirred for separation, the residue is extracted by high-pressure hot water, further extracted by alkali and reductive salt, and finally extracted by acid, and the panax japonicus polysaccharide which can be dissolved in water and DMSO and not be dissolved in methanol, ethanol and acetone is obtained by separation, neutralization by taking the solution, dehydration, protein removal, decolorization, desalination and drying. The panax japonicus polysaccharide which is prepared by the invention has higher anti-tumor activity and promotion of immune activity, which can be used for preparing drugs or health care products for improving immune function and anti-tumor. The method for preparing the product is simple and easy to operation, and the sources of the needed raw materials are wide.

The invention relates to the technical field of nano-selenium hydrosol, in particular to a nano-selenium hydrosol with anti-tumor activity and its preparation, preservation method and application. The hydrosol at least contains components with the following concentrations: 0.5mmol / L-5.0mmol / L of nano-selenium; 100.0mg / L-600.0mg / L of versicolor polysaccharide protein. The preparation method of the hydrosol at least includes step S01. adding a solution containing selenium ions and / or selenium ions to the polysaccharide protein aqueous solution of versicolor versicolor; step S02. adding a reducing agent solution dropwise to the mixed solution obtained in step S01, and shaking; Step S03. The product obtained from the reduction reaction in step S02 is subjected to constant volume and dialysis treatment. The hydrosol exists stably at 2-10°C. Because the polysaccharide protein of Yunzhi polysaccharide has hydrophilic hydroxyl and amino groups, these two groups can enhance the affinity between nano-selenium and cancer cells, increase the uptake of nano-selenium by tumor cells, and then reduce the dosage of drugs and increase the curative effect The overall therapeutic effect with less toxic and side effects provides a more effective solution for clinical combination chemotherapy of cancer.