109results about How to "Preserving ability" patented technology

Methods, devices and systems for efficient 3D printing that address conventional inefficiencies while utilizing a single compact device are set forth. Some embodiments utilize a circular-shaped build area revolving symmetrically around a single center point utilizing a continuous helical printing process. In one embodiment a liquid photopolymer for solidification is deposited on a build platform to form the physical object The Build platform is continuously rotated and simultaneously raised in a gradual programmed manner. Focused from below the platform produces a single continuous “layer” of material deposited and bonded in a helical fashion.

A system and method is provided for asynchronously sharing, backing up, and distributing data based on immutable entries. The system which is layered upon an existing operating system automatically stores, queues and distributes requested data among users.

A client node is communicatively coupled to a gateway node via a TCP / IP network. One or more constrained devices that include a wireless receiver / transmitter circuit communicate with the gateway node via a wireless network. The gateway node includes a web server that provides a dynamic web page accessible by the client node that has a list of the one or more active constrained devices on the wireless network. Each device entry in the list includes a URL that acts as an entry point for the client node to communicate with a web server in a corresponding constrained device. The gateway node automatically discovers a new device on the wireless network and populates the list of the one or more active constrained devices with the newly present constrained device. The new constrained device may be detected based on a periodic message sent by the constrained device indicating the constrained device has turned on its receiver / transmitter circuit for a period of time.

The present invention relates to an avirulent, oncolytic herpes simplex virus modified from a wild-type herpes simplex virus so that both γ134.5 genes of the virus have been deleted and each replaced with an interferon-resistance gene that is expressed as an immediate-early gene. The present invention also relates to a pharmaceutical composition that includes the modified herpes simplex virus of the present invention and a pharmaceutically acceptable vehicle for in situ administration to tumor cells. Also provided in the present invention are methods for killing tumor cells in a subject and for immunizing a subject against an infectious disease, cancer, or an autoimmune disease that involve administering to a subject the modified avirulent, oncolytic herpes simplex virus of the present invention.

A method and article of manufacture for encoding file metadata into a file name used in a computer system is disclosed. Metadata is added to an original file name and extension created by a user. The metadata may be in the form of a left padded, monotonically increasing number which operates similar to a time stamp. The file extension is then duplicated following a delimiter to preserve a user's ability to search for the original file name and extension, while maintaining functional identification of the file type to the operating and / or file system.

Methods and apparatus for simulating the sound of a specific percussion instrument. A first stored waveform representative of the impulse response of the specific percussion instrument is convolved with a second waveform representating of the vibrations produced when a playing surface is struck, scraped or rubbed by a hand-held implement manipulated by a human player. A control interface produces a control signal indicative of a desired audio effect, and a signal processor modifies the spectral components of the output waveform produced by the convolution in response to the control signal to produce a modified output waveform that manifests the desired audio effect.

A personal alarm system can be worn or carried by the user, may be activated at any time by the user and / or may be automatically activated to send a signal to any remote monitoring station on the network. The device identifies the user as well as the user's location within the monitored area. The alarm-sending unit is designed to fit within a box the size of a small cell phone or pager. The unit includes an ID memory for identifying the user, is programmable and has an on-board processor for generating a signal to a wireless transmitter for sending the signal to a to a local receiver for inputting the signal onto the network. A centralized, networked RF receiver is used with the personal alarm unit and one or more of these RF receivers may be installed in order to provided adequate coverage of the monitored area. The signals generated by the personal alarm are received by the RF receiver(s) and decoded, whereupon the system processor assembles a message, packetizes it as necessary, and sends it to one or more monitoring stations via the intervening network and network interface. The signals may be digitized where desired. A beacon generator may be used to identify location of the portable unit. The system may also employ a GPS generator to identify location.

Methods and devices for increasing revascularization in an ischemic heart and for reducing muscle mass or volume in congestive heart failure patients are described. The method includes using laser energy to create microchannels in the target tissue. The microchannels are separated from each other to maintain tissue that is untreated or undamaged by laser energy. Such undamaged tissue augments angiogenesis. The method also includes delivery of bioactive agents that are angiogenic. The apparatus simultaneously creates a plurality of microchannels that are separated from each other and thereby promote angiogenesis, revascularization and / or muscle reduction.

An active antenna power interface circuit couples a supply voltage from a radio receiver to an antenna feed. The circuit comprises a DC power input and a power switching element connected in series between the DC power input and the antenna feed. The power switching element has a control input for selecting a conducting state or a nonconducting state of the power switching element. A high side voltage sensor senses a first voltage proportional to a voltage at the DC power input. A low side voltage sensor senses a second voltage proportional to a voltage at the antenna feed. A controller is coupled to the control input and to the voltage sensors. The controller places the power switching element into the conducting state, samples the first and second voltages, calculates a voltage difference in response to the first and second voltages, compares the voltage difference to an upper limit and a lower limit. If the voltage difference is greater than the upper limit then the controller signals a short-circuit fault. If the voltage difference is less than the lower limit then the controller signals an open-circuit fault.

An anchoring assembly for securing an electrical fixture to a connection box. The assembly may include a receiver having a first engagement mechanism. The receiver may be formed to receive an anchor exclusively by translation in the longitudinal direction. The anchor may have a second engagement mechanism formed as a cantilever extending in substantially the longitudinal direction. The second engagement mechanism may support at least one engagement location. Additionally, the second engagement mechanism may be arranged to deflect when, upon insertion, an engagement location of the at least one engagement position passes the first engagement mechanism.

A circuit is provided which protects the measuring input of an impedance tomograph from damage due to overvoltage. A resistor capacitor (RC) series connection is provided as a protective circuit at the measuring input.

A connection box assembly includes an electrical connection box with one end shaped to receive a fastener for securing the connection box to a stud or other structural member. The other end is secured to a slide. A spacer is inserted within the slide to register the connection box with respect to any sheathing, sheetrock, or paneling material applied to a back side of the stud or other structural member. The slide engages the spacer with a uni-directional ratchet controlling the extension of the spacer from the connection box.

The present invention relates to a resveratrol-containing composition capable of modulating gene expression to an extent greater than that observed with resveratrol alone or with calorie restriction. The invention particularly pertains to such resveratrol-containing compositions that comprise resveratrol, a chelator, hyaluronic acid, and / or vitamin D and which upon administration to a recipient, increases the concentration or activity of a survival / longevity gene product and / or decreases the concentration or activity of a gene product that induces or causes cellular damage. Most preferably, the resveratrol-stabilizing composition will comprise the chelator phytic acid (inositol hexaphosphate; IP6), hyaluronic acid, and vitamin D. The invention further pertains to the use of such compositions in the treatment or prevention of cancer, cardiovascular disease, diseases associated with aging, and other conditions and illnesses.

A stochastic algorithm has been developed for predicting the drug-likeness of molecules. It is based on optimization of ranges for a set of descriptors. Lipinski's “rule-of-5”, which takes into account molecular weight, logP, and the number of hydrogen bond donor and acceptor groups for determining bioavailability, was previously unable to distinguish between drugs and non-drugs with its original set of ranges. The present invention demonstrates the predictive power of the stochastic approach to differentiate between drugs and non-drugs using only the same four descriptors of Lipinski, but modifying their ranges. However, there are better sets of 4 descriptors to differentiate between drugs and non-drugs, as many other sets of descriptors were obtained by the stochastic algorithm with more predictive power to differentiate between databases (drugs and non-drugs). A set of optimized ranges constitutes a “filter”. In addition to the “best” filter, additional filters (composed of different sets of descriptors) are used that allow a new definition of “drug-like” character by combining them into a “drug like index” or DLI. In addition to producing a DLI (drug-like index), which permits discrimination between populations of drug-like and non-drug-like molecules, the present invention may be extended to be combined with other known drug screening or optimizing methods, including but not limited to, high-throughput screening, combinatorial chemistry, scaffold prioritization and docking.

A scalable hierarchical coreference method that employs a homomorphic compression scheme that supports addition and partial subtraction to more efficiently represent the data and the evolving intermediate results of probabilistic inference. The method may encode the features underlying conditional random field models of coreference resolution so that cosine similarities can be efficiently computed. The method may be applied to compressing features and intermediate inference results for conditional random fields. The method may allow compressed representations to be added and subtracted in a way that preserves the cosine similarities.

A gimbal support that senses rotational displacement and provides haptic feedback in one, two or three dimensions of a manually-operated control member used to generate control inputs using a single hand while also limiting cross-coupling.

A method of communicating data between a client and a server includes initiating a participating application for transmitting packets between a client and a server. The participating application participates in a transport protocol. The method also includes initiating a non-participating application for transmitting packets between the client and the server. The non-participating application does not participate in the transport protocol. Additionally, the method includes determining whether to transmit a packet from the client to the server using the participating application or the non-participating application.

A method of trafficking telecommunication signals having various formats, includes providing, at a first network element, a synchronous payload envelope having a first format, the synchronous payload envelope comprising a synchronous path and associated overhead portion and a payload portion, mapping the synchronous payload envelope into a transport signal having a second format without terminating the synchronous path or associated overhead portion of the synchronous payload envelope, and transmitting the transport signal to a second network element over a network supporting the second format.

A peptide which selectively inhibits αvβ3 integrin which comprises the deamidation product of a peptide comprising the NGR motif.

A goggle having features of the present invention comprises a transparent housing with an arcuate upper surface with a first end and a second end, a planar frontal surface, a centrally disposed nose bridge and a first and second lower panel disposed opposite the nose bridge. The first and second lower panel join the arcuate upper surface proximate the arcuate upper surface first end and second end while the housing is contoured to conform to the topography of the wearer's face. Vents are disposed adjacent the nose bridge and means for supporting the goggle on the head of the wearer.

An electrical fixture comprising a body, first flange, and second flange. The body may have a terminal for securing a transmission line. The first flange may secure to the body to extend away therefrom toward a first end. The second flange may secure to the body to extend toward a second end. The first and second flanges may each include a pair of ears, the first and second pairs of ears being located proximate the first and second ends, respectively. The ears of the first and second pairs of ears may be spaced apart in a third direction substantially orthogonal to the first and second directions. The ears may be formed to have an extended portion, most distant from the body, and a recessed portion, spaced away from the extended portion toward the body and presenting an edge extending in the third direction.

A connection box system comprising an anchor configured to be removably secured to a fixture for delivery of a signal to a consuming device. The anchor may have a first engagement mechanism. A connection box may be configured to house lines proceeding from a signal source and terminating in the connection box for connection to the fixture. A receiver may be configured in association with the connection box to receive and retain the anchor. The receiver may have a second engagement mechanism to engage the first engagement mechanism of the anchor when the anchor is inserted therein without the aid of tools.

Systems, methods, and computer program products for searching objects, metadata associated with the objects, and attributes assigned to or associated with the metadata. Referring to herein as metadata for the metadata, these attributes may be associated with one or more metadata field values of a metadata field name which, in turn, may be associated with an object being or already indexed in a search index of a search system. Each attribute may be optional, dynamically created, indexed, and searchable via the search index. There can be multiple attributes associated with the same metadata field value, each being represented as a key-value pair. This metadata for the metadata approach can be highly efficient. For example, the ability to search multiple attributes associated with the same metadata field can eliminate the potential need to create multiple metadata fields for the same value in different languages, countries, etc.

There is provided an adornment having a machine readable code integrated therein for establishing a communication channel over a network between a computing device and a server, the adornment comprising an adornment body sized and shaped for wearing on an appendage of a body of a human, wherein the machine readable code comprises a plurality of gems which are inlaid in the adornment body, wherein the machine readable code encodes an identifier for establishing the communication channel between a computing device imaging said plurality of gems and a remote data storage device storing at least one media content item designated for presentation on a display of the computing device.