The invention provides a method for screening an anaerobion
traditional Chinese medicine inhibitor based on a Fe-Ta-Cu-B
nanoprobe, and belongs to the technical field of development and application of
traditional Chinese medicine. The method is characterized in that the Fe-Ta-Cu-B nanoprobenanoprobe is prepared and used as the basis for screening an anaerobion
traditional Chinese medicine formula; the property that a paramagnetic Fe-Ta-Cu-B nanoprobenanoprobe prepared by
antibody-
coating is capable of performing specific binding with target
bacteria and the influence of the paramagnetic property of Fe-Ta-Cu-B on
nuclear magnetic resonance relaxation time are utilized for detecting whether a sample contains the target
bacteria. The paramagnetic Fe-Ta-Cu-B
nanoprobe shows a
linear relation with the
nuclear magnetic resonance relaxation time within a certain range, that is, if the nano Fe-Ta-Cu-B content is high, the
nuclear magnetic resonance spin-lattice relaxation time and spin-
spin relaxation time of the sample are small, and the target
bacteria can be quantitatively detected within a certain range, and as a result, the bacteria inhibition effect of the traditional Chinese
medicine formula can be indirectly assessed. The method is applicable to the screening of the traditional Chinse
medicine formula capable of inhibiting anaerobion; and the development of a traditional Chinese
medicine product is sped up.