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85 results about "Order Rodentia" patented technology

Rodents (from Latin rodere, "to gnaw") are mammals of the order Rodentia, which are characterized by a single pair of continuously growing incisors in each of the upper and lower jaws.

Method for generating anti-variable region monoclonal antibodies

Methods for generating anti-variable region monoclonal antibodies in rodents are disclosed. The anti-variable region mAbs are useful as therapeutic agents, diagnostic agents or research reagents.
Owner:CENTOCOR

Humanized Rodents that Express Heavy Chain Containing VL Domains

Non-human animals, tissues, cells, and genetic material are provided that comprise a modification of an endogenous non-human heavy chain immunoglobulin sequence and that comprise an ADAM6 activity functional in a rodent (e.g., a mouse), wherein the non-human animals rearrange human immunoglobulin light chain gene segments in the context of heavy chain constant regions and express immunoglobulin-like molecules comprising human immunoglobulin light chain variable domains fused to heavy chain constant domains that are cognate with human immunoglobulin light chain variable domains fused to light chain constant domains.
Owner:REGENERON PHARM INC

Methods of using [3.2.0] heterocyclic compounds and analogs thereof

Disclosed are methods of treating cancer comprising administering to the animal, a therapeutically effective amount of a heterocyclic compound of Formula VI. The animal is a mammal, preferably a human or a rodent.
Owner:TRIPHASE RES & DEV I

Electrocution animal trap with a sender

An electrically powered rodent trap which includes a surveillance system for remote surveillance of the trap so that the trap may be operated without being attended to. A rodent which enters into the trap is killed by means of electrocution electrodes. The dead rodent is automatically dispatched from the trap, e.g. by a trapdoor, into a container or reservoir beneath the trap. The number of electrocutions and possible other data is stored by an electronic system incorporated in the trap and a signal is sent out, either by request from an external unit, or automatically to an external unit. A city rodent exterminator is capable of monitoring the status of the trap from an office location and thereby effectively tend to the trap or to a series of traps.
Owner:RATCO

Methods of using [3.2.0] heterocyclic compounds and analogs thereof

Disclosed are methods of treating cancer comprising administering to the animal, a therapeutically effective amount of a heterocyclic compound of Formula VI. The animal is a mammal, preferably a human or a rodent.
Owner:TRIPHASE RES & DEV I

Snap trap enclosure for trapping and killing rodents

InactiveUS20060156617A1Safe and efficient and effectiveAnimal trapsInsect catchers and killersDecoyOrder Rodentia
A device for trapping and killing rodents includes a narrow box-like enclosure having an entrance opening through which the rodent passes face first into the enclosure, and an opposite rear wall from which a bait shelf inwardly projects for the placement of bait thereon, with a snap trap positioned between the entrance opening and the bait so that the rodent must walk over the trap at the trap's most lethal orientation which is straight forward thereby unavoidably triggering the trap and killing the rodent. A pair of clips positioned within the enclosure adjacent the rear wall secure the trap in position and prevent the trap from flipping up when triggered, and the both the rear wall and the roof are hinged so they can be opened for replacing the bait without disturbing the trap and for removing both the bait and trapped rodent so that the enclosure can be re-baited and the trap reset or replaced. The device is also collapsible to a flat disposition to facilitate storage, transport and cleaning.
Owner:HALE BRIAN

Humanised antibodies

CDR-grafted antibody heavy and light chains comprise acceptor framework and donor antigen binding regions, the heavy chains comprising donor residues at at least one of positions (6, 23) and / or (24, 48) and / or (49, 71) and / or (73, 75) and / or (76) and / or (78) and (88) and / or (91). The CDR-grafted light chains comprise donor residues at at least one of positions (1) and / or (3) and (46) and / or (47) or at at least one of positions (46,48, 58) and (71). The CDR-grafted antibodies are preferably humanised antibodies, having non human, e.g. rodent, donor and human acceptor frameworks, and may be used for in vivo therapy and diagnosis. A generally applicable protocol is disclosed for obtaining CDR-grafted antibodies.
Owner:UCB PHARMA SA

Humanised antibodies

CDR-grafted antibody heavy and light chains comprise acceptor framework and donor antigen binding regions, the heavy chains comprising donor residues at at least one of positions (6, 23) and / or (24, 48) and / or (49, 71) and / or (73, 75) and / or (76) and / or (78) and (88) and / or (91). The CDR-grafted light chains comprise donor residues at at least one of positions (1) and / or (3) and (46) and / or (47) or at at least one of positions (46, 48, 58) and (71). The CDR-grafted antibodies are preferably humanised antibodies, having non human, e.g. rodent, donor and human acceptor frameworks, and may be used for in vivo therapy and diagnosis. A generally applicable protocol is disclosed for obtaining CDR-grafted antibodies.
Owner:UCB PHARMA SA

Snap trap enclosure for trapping and killing rodents

PendingUS20060156615A1Safe and efficient and effectiveAnimal trapsInsect catchers and killersDecoyEngineering
A device for trapping and killing rodents includes a long, narrow box-like enclosure having an entrance opening at a first end through which the rodent passes face first into the enclosure, and an opposite rear end having rear wall from which a bait shelf inwardly projects for the placement of bait thereon, with a snap trap located between the entrance opening and the bait so that the rodent must walk over the trap at the trap's most lethal orientation which is straight forward thereby unavoidably triggering the trap and killing the rodent. A pair of clips positioned within the enclosure adjacent the rear wall secure the trap in position and prevent the trap from flipping up when triggered, and the both the rear wall and the roof are hinged so that they can be opened for replacing the bait without disturbing the trap and for removing both the bait and trapped rodent so that the enclosure can be re-baited and the trap reset or replaced.
Owner:HALE BRIAN

Pest control device

A poison bait device having a poison bait container which, in operation, is accessible to rodents such as rats and mice but which is inaccessible to other creatures including humans, birds, dogs, cats and the like, wherein the only access to the bait well is thru a relatively small diameter tube having a tortuous path such as curves thru which rats and mice must slither, and wherein the entrance(s) to said tube is generally planar and adapted for sufficiently close to the ground and substantially parallel to the ground plane whereby children, pets and birds cannot reach the bait.
Owner:DEAKINS JOSEPH M

Rodent bait station

An embodiment of a bait station comprises a rotatable lid and air-tight bait compartments. An additional compartment also contains bait and is accessible to rodents as they enter the station. The rotatable lid is configured to hold the bait within the compartments and can be rotated in order to replace the previously accessible bait with fresh bait from a different compartment. A key can be attached to an extension pole in order to unlock and rotate the rotatable lid without requiring a person to kneel down or bend over. A base having two entrances provides an inviting environment for rodents.
Owner:TECHNICIDE

Rodent trap

InactiveUS20060026893A1Animal trapsDecoyEngineering
Rodent Trap with a lid, a pivot plank, a ferrous metal rectangular open topped box, a magnet, a pivot point, a food holding platform, a guide panel, a climbing ramp or rope and a rodent receptacle. The guide panel and the bait tray are fixed at one end of the rectangular box. The box has half of the floor removed. The pivot point holds the plank so that it can rotate. The pivot plank includes a magnet on its underside. The magnet is attracted to the ferrous metal portion of the floor of the box so that a rodent can climb up the ramp, travel along the pivot plank, wedge itself between the pivot plank and the guide panel in the pursuit of bait causing the magnetic attraction to break and the pivot plank to rotate down causing the rodent to drop into the receptacle below the rectangular box.
Owner:SEARS RICHARD B

Non-Human Animal Models for B-cell Non-Hodgkin's Lymphoma and Uses Thereof

Disclosed are non-human animal models, and preferably, rodent models, and more preferably, mouse models, of B-cell Non-Hodgkin's Lymphoma (NHL). In particular, the present invention provides animal models of B cell NHL including, B cell chronic lymphocytic leukemia / lymphoma (B-CLL), Burkitt's lymphoma (BL), Follicular-like lymphoma (FLL) and Diffuse large B-cell lymphoma (DLBCL), as well as various methods for producing these non-human animal models. These animal models, as well as cell lines produced from or derived from these models, are useful tools for a variety of methods, including, but not limited to, preclinical testing of drug candidates, and particularly drug candidates that are specific for human proteins, and any research, development, pharmaceutical, or clinical purpose, including but not limited to, the identification, development, and / or testing of drugs (therapeutics, prophylactics, etc.), targets, markers, and / or research tools for use in the diagnosis of, study of, or treatment of any Non-Hodgkin's Lymphoma, such as those described herein, or for any related condition.
Owner:NAT JEWISH MEDICAL & RES CENT

Tamper resistant weighted rodent and insect bait station

The present invention provides a bait station and method for securing it using a receptacle for holding a weight to weight a bait enclosure and by stakes formed as a unitary part of the enclosure for securing the enclosure
Owner:VM PRODS

Screening tool for antiviral agents

A method is provided for screening anti-adenovirus agents. The method includes reducing the activation of the immune system of a small mammal, administering a human adenovirus vector to the small mammal, monitoring the tumor cells in the mammal, and analyzing infectious virus units within the tumor cells and the organs of the small mammal. Specifically, the immune system of the small mammal is suppressed using cyclophosphamide. The small mammal may be, but is not limited to, one of the following: mice, rabbits, cotton rats, hamsters, rats, and other small rodents.
Owner:SAINT LOUIS UNIVERSITY

Repelling rodents

A rodent repellent device has a housing substantially enclosing a porous storage medium in an interior region of the housing; and a repellent disposed within the storage medium, the repellent including a component of feline urine that disperses into atmospheric air at room temperature.
Owner:ARMEX

Loading dock seal with flow through vent

A loading dock seal has one or more recesses formed within the loading dock seal and covered by a transparent material. Mesh segments are utilized to screen some of the recesses to reduce rain, snow, rodents, insects and debris from passing through the recess passageway to the loading dock. A further transparent or opaque mesh segment cover can be utilized to selectively cover one or more of the mesh segments.
Owner:SHELTON MICHAEL J

Rodent trap system with alarm

A rodent trap system for alerting a user that a rodent has been trapped having a base panel, a top surface, three lips extending upwardly from three ends of the base panel wherein the lips create an enclosure, a lid pivotally attached to the second and third lips, an alarm housing on the base panel, a flange extending outwardly from the alarm housing formed by the lips which can pivot; a first half contact on a bottom surface of the flange, a second half contact on the top surface of the base panel, the contacts are connected to the actuator or solenoid and to a speaker in the alarm housing, wherein when the contacts contact each other they send an electrical signal causing the actuator or solenoid to pull a plunger to move the lid to the closed position and causing the speaker to emit the sound.
Owner:HARVEY RALPH +1

Device and method of identification and classification of rodent cognition and emotion

The field of this invention is classifying animal behaviors. In particular the fields of this invention include using animals in vivariums, such as rodents, particularly mice. In a vivarium cage, mice generate ultrasonic vocalizations and video behaviors. Their phenotype may also change. Starting with known cognitions or emotions, then comparing the vocalizations, changes to phenotype and video behaviors identification, classification and correlations of cognition or emotion may be generated. These new identifications, classifications and correlations are then used to update the starting set of cognition and emotion of the study animals, in a continuous feedback.
Owner:VIUM INC

Methods and compositions for treating ineffective erythropoiesis

InactiveUS20170327800A1Improve the level ofIncrease red blood cell and hemoglobin levelPeptide/protein ingredientsTransferasesIneffective erythropoiesisPrimate
In certain aspects, the present invention provides compositions and methods for increasing red blood cell and / or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
Owner:ACCELERON PHARMA INC

Rodent-resistant air-conditioning preservative film for grain

The invention discloses a grain preservative film of modified-atmosphere packaging for rat control which contains capsaicin microcapsule. The film is prepared by components of polyethylene resin, polyvinyl acetate, zinc stearate, calcium stearate, light calcium carbonate, white carbon black, paraffin wax, antioxidant and fluorescent agent. The components are weighed and mixed proportionally, extruded by a single screw plastic extruder, and subject to blow moulding to prepare a film. Capsaicin microcapsule, as a raticide, is coated on outer surface of the plastic film by an adhesive to prepare grain preservative film of modified-atmosphere packaging for rat control. The raticide slowly and continuously releases, thus achieving objective of long-term effective rat control, and has bidirectional atmosphere modifying function on O2 and CO2, with good moisture permeability of small packages, good antifogging and antisweat performance and oxidation resistance and anti aging ability.
Owner:天津市食品加工工程中心 +1

Ridge Vent Cap

A ridge vent end cap that can be readily bent to conform to roofs of varying pitches while enclosing ridge vents of various styles. The end caps are bent and fashioned for a flat blank, which is configured to allow it to be bent and formed into a shape that accommodates various styles of ridge vents and that encloses ridge vents on roofs with varying pitches. The bent finished end cap has a top ridge beam and a pair of end panels, bottom flaps and corner flaps. Each corner flap has its own top corner flap and a bottom corner flap. A preformed key hole slot along the central axis / plane of the blank or finished end cap allows the end cap to bend without buckling so that the end panels slide over one another to enclose the end open of the ridge vent while conforming to the pitch of the roof. A tooth is formed in one of the bottom flaps, which bites into the roof shingles helps ensure that the end panels cannot be pried up or burrowed under by rodents and insects.
Owner:STOUFFER TECH

DNA immunocontraceptive vaccines and uses thereof

The present invention provides an immunocontraceptive vaccine comprising a recombinant bacterial host that has been modified to produce egg- or sperm-specific polypeptide such as the sperm-specific protein lactate dehydrogenase-C (LDH-C). When animals such as rodents eat these bacteria, their immune systems produce antibodies that attack their sperms. Not only would the males have less viable sperm, the females would also have antibodies to sperm entering their reproductive systems. Immunocontraception is an attractive method for reducing the population size of animals with high fecundity, and sterilizing animals using such immunocontraceptives can reduce targeted animal populations to acceptable levels in an efficient, cost-effective, humane and, importantly, a species-specific manner.
Owner:RES DEVMENT FOUND

Modified viral vector particles

InactiveUS20060035378A1BiocideVectorsPrimateHeifer calf
This invention relates to viral vector particles, including capsid proteins with an attachment site for the specific chemical modification of the vector particles. Furthermore, the invention relates to procedures for the production of these viral vector particles. Furthermore, the invention relates to the use of these viral vector particles as a therapeutic, prophylactic or diagnostic means in humans and primates as well as other vertebrates like cattle, pigs, birds, fish, or rodents.
Owner:KOCHANEK STEFAN +1

Check valve mechanism for rodents and/or odors

InactiveUS20070215216A1Water closetsCheck valvesUngulaCheck valve
A check valve mechanism for use with a vertical drain pipe comprises a connector portion for supporting the check valve mechanism with respect to the drain pipe, and two flaps, each being an ungula of a cylindrical tube. The flaps are pivotally connected to the connector portion, so as to be displaceable between a closed position in which the flaps are against one another such that peripheral portions of the flaps are collinear at a connection line to obstruct the drain pipe, and an opened position, in which the flaps are away from one another to allow liquids / solids to pass through the check valve mechanism and the flaps.
Owner:FARRUGGIA PASQUALE

Fixing device for endotracheal intubation of rodents

A fixing device for endotracheal intubation of rodents is provided. The fixing device includes: a bed configured to place a rodent thereon; a support member attached to an upper end portion of the bed in a transversely movable manner and supporting a gas supply pipe through which an anesthetic gas is supplied to the nose of the rodent; and a fastening member configured to fix the support member to the upper end portion of the bed after an end portion of the gas supply pipe is aligned with the nose of the rodent.
Owner:SAMSUNG ELECTRONICS CO LTD

Mice heterozygous for WFS1 gene as mouse models for depression

The present invention describes a recombinant rodent model for depression. More particularly, the rodent comprises cells expressing mutations in the WFS1 gene. The rodent is preferably a mouse heterologous for mutations in exon 8 of the WFS1 gene. Preferably, the mutations yield a non-functional wolframin protein that lacks all or some of it transmembrane regions. Methods and compositions for making and using the mouse and cells thereof are disclosed.
Owner:PHARMACIA & UPJOHN CO
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