The invention discloses a method and a device for configuring the water resource. The method comprises the steps of A, establishing an optimized model by taking land utilization maximization and water consumption minimization as a goal and taking surface water capacity constraint, available water capacity constraint of underground water, surface water irrigation proportion constraint, irrigation water requirement constraint, land utilization constraint, water reservoir capacity constraint and irrigation water capacity non-negativity constraint as constraint conditions; B, disassembling the optimized model into an upper bound sub model and a lower bound sub model according to a region interactive algorithm, introducing penalty coefficients through a type-2 fuzzy type reduction method, converting the upper bound sub model and the lower bound sub model into corresponding linear programming models, and solving the linear programming models; C, selecting different underground water use proportions, bringing the different underground water use proportions into the optimized model to compute, and obtaining a relationship between the underground water use proportions and a crop planting structure. By utilizing the method and the device, disclosed by the invention, the plan on water resource utilization under multiple uncertain conditions can be carried out, and a reasonable agricultural irrigation method can be provided.