32 results about "Nigella arvensis" patented technology

The invention provides herbal compositions with antiviral properties comprising extracts of Foeniculum vulgare, Nigella sativa, Centaurium erythrae (spicatum or pulchellum), Cynara cardunculus var scolymus, Inula helenium (viscosa), Solenostema argel, Sesbania aegyptiaca (sesban), Cichorium intybus (pumilum), Cymbopogon proximus, Hemidesmus indicus, Rheum officinale, Cuminum cyminum, and combinations thereof. The invention further provides herbal compositions with antiviral properties comprising an extract from the leaves or seed of Sesbania aegyptiaca (sesban) and at least one additional herbal extract selected from the group consisting of seed of Nigella sativa, shoot of Cichorium intybus (pumilum), whole plant of Cymbopogon proximus, rhizome of Hemidesmus indicus, leaves of Solenostema argel, rhizome of Rheum officinale, and fruit of Ecballium elaterium. The present invention also provides methods for treating a subject with a viral infection, particularly infections with hepatitis B virus or hepatitis C virus. The methods comprise administering to a subject an effective amount of a herbal composition selected from among the herbal compositions of the invention.

The invention provides a Chinese herbal composition which comprises semen nigellae, eclipta, black beans, polygonum multiflorum, fructus psoraleae, crocus sativus, madder, woad, Chinese gall leaven, selaginella, salt, iron vitriol, lemon, water soluble beewax, safflower seed oil, rosemary essential oil, thyme essential oil, and peppermint essential oil. The Chinese herbal composition is paste prepared from the natural Chinese herbal raw materials, is non-irritant, has no toxic and side effect, and is fast and firmer in dying when being compared with the conventional plant hair dye. The method adopts a low-alcohol low-temperature hot-reflux traditional Chinese medicine extracting technology, so as to improve effective constituent dissolving out rate and promote transdermal absorption. The paste is lubricating, is convenient to smear and clean, can not only shield white hair, but also care and protect hair, and inhibit, delay and reduce generation of white hair. The Chinese herbal composition being paste is mainly used for hair dying and nourishing of white hair, yellow hair and other light-colored hair.

The invention relates to the technical field of Chinese medicinal material indentifying methods, in particular to a method for identifying a Nigella glandulifera Freyn medicinal material, which comprises the following steps of: 1, establishing a standard fingerprint of the Nigella glandulifera Freyn medicinal material; 2, testing a fingerprint of a sample of the Nigella glandulifera Freyn medicinal material to be tested by the step same as the step 1; and 3, comparing the fingerprint of the sample of the Nigella glandulifera Freyn medicinal material to be tested with the standard fingerprint of the Nigella glandulifera Freyn medicinal material, and screening the Nigella glandulifera Freyn medicinal material according with the standard fingerprint of the Nigella glandulifera Freyn medicinal material. Compared with the prior art, the method has the characteristics of simpleness, convenience, high accuracy, and high stability and repeatability. The standard fingerprint established by the method is utilized to effectively identify the Nigella glandulifera Freyn medicinal material and effectively monitor and control the inner quality of the Nigella glandulifera Freyn medicinal material.

The invention provides a traditional Chinese medicine composition for curing climacteric syndrome of women. The bulk drugs of the traditional Chinese medicine composition include fennelflower seeds, rhizoma curculiginis, fructus rosae laevigatae, semen boitae, polygala tenuifolia, cistanche, selfheal, seeds of feather cockscomb, semen sesami nigrum, eclipta, golden cypress, tortoise shell glue, curcuma zedoary, pollen typhae, lignum dalbergiae odoriferae, Chinese yam, acanthopanax, panax japonicus, radix paeoniae alba, roots of red-rooted salvia, folium apocyni veneti, uncaria, semen phaseoli, caulis bambusae in taeniam, oyster, roots of bidentate achyranthes, Changium smyrnioides, pericarpium citri reticulatae, semen coicis and liquorice. The traditional Chinese medicine composition shortens the course of treatment, improves curative effect, reduces recurrence possibility, improves living quality, and avoids side effects and complications.

Disclosed are compositions enriched with thymohydroquinone, further comprising of thymoquinone, hederagenin and / or α-hederin formulated by blending the active molecules isolated from the seeds of Nigella sativa. Also disclosed are novel processes for the isolation of bioactive components thymohydroquinone, thymoquinone from the seeds of Nigella sativa. A process for the isolation α-hederin and hederagenin from the spent material of Nigella sativa is also disclosed herein.

The invention discloses a composition and a preparation for improving human alopecia and hair growth and a preparation method of the composition. The composition is prepared from the following components: 0.05 to 1 part of biotin tripeptide-1, 0.05 to 1 part of myristoyl pentapeptide-17, 0.01 to 1 part of glossy privet fruit extract, 0.01 to 1 part of herba ecliptae extract, 0.01 to 1 part of cortex dictamni extract, 0.01 to 1 part of radix sophorae flavescentis extract and 0.01 to 1 part of cortex mori radicis extract. 0.01 to 1 part of cacumen biotae extract, 0.01 to 1 part of radix polygoni multiflori extract, 0.01 to 1 part of radix angelicae sinensis extract, 0.01 to 1 part of agilawood extract, 0.01 to 1 part of semen nigellae extract and 0.01 to 1 part of holy basil extract. The composition is a traditional Chinese medicine compound and biological polypeptide composition, can improve alopecia and promote blackening and densification of hair, can be applied to anti-alopecia and hair growth products, and comprises shampoo, hair conditioners, hair care essential oil, hair masks, eyebrow and eyelash growth liquid and the like.

The invention provides a traditional Chinese medicine composition for treating seborrheic alopecia. The traditional Chinese medicine composition comprises paniculate swallowwort root, chloranthus spicatus, agastache, densefruit pittany root-bark, rosemary, root of hollyhock, vernonia, carthamus tinctorius, seed cowherb, ginseng leaves, sanchi flowers, semen nigellae, fructus psoraleae, black bean, peppermint camphor, borneol and kaoliang spirit. The traditional Chinese medicine composition is in the form of tincture which is formed by conducting extraction on pure traditional Chinese medicine, is fastidious and mild in formula, and simple and easy in preparation, and is mainly used for hair holding, hair regrowing, oil controlling, fat removing, acarus killing, detoxifying, dandruff removing, wind-evil dispelling and itching relieving. The tincture is high in hair regrowth efficiency and lasting in curative effect, and has the advantages that the 'ecological environment' of scalp can be improved synchronously while the purpose of hair regrowth is realized; the symptoms such as greasy scalp, too much dandruff, pruritus, epifolliculitis and seborrheic dermatitis can be treated effectively; the rebound possibilities of the symptoms are low after a user stops taking the traditional Chinese medicine composition; toxic or / and side effects are avoided; the use is safe; the traditional Chinese medicine composition can be used in preparation of medicine for treating seborrheic alopecia.

Disclosed are compositions of matter, treatments and protocols useful for reduction of expression and / or activity of indolamine 2,3 deoxygenase (IDO). In some embodiments the invention teaches the administration of a therapeutic combination of ingredients comprising of pterostilbene, Nigella sativa, sulforaphane, and epigallocatechin-3-gallate (EGCG) to a mammal at possessing an increased expression and / or activity of said IDO in which reduction of number and / or activity is desired. In another embodiment, the invention teaches administration of said therapeutic combination to a mammal infected with viral and / or bacterial infections and / or neoplasia. In some embodiments dosage of said therapeutic combination is based on inflammatory and / or immunological parameters observed in patients.

The invention relates to a traditional Chinese medicine composition with hair growing and blacking effects and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from pure traditional Chinese medicines including radix bupleuri, semen persicae, semen nigellae, pomegranate seeds, semen sesami nigrum and beet and medically acceptable auxiliary materials including menthol, tetrahydropiperine, azone and simethicone through the steps of mixing, smashing, supercritical extraction and edible alcohol extraction, a stock solution is obtained through concentration, menthol, tetrahydropiperine, azone and simethicone are added into alkyl glycoside, and the materials are uniformly stirred and mixed to obtain a stock solution B; and the composition is prepared from the stock solution A and the stock solution B through uniform mixing. The composition is low in cost, natural, environmentally friendly, convenient to use, simple in preparation process, definite in curative effect, economical and practical. When the obtained composition is applied to an affected part, growth of melanocytes at the bottom of hair follicles can be stimulated, and the hair can recover to be black and dense. Through observation for 100 patients using the traditional Chinese medicine composition provided by the invention, the cure rate is 64%, the effective rate is 95%, and the ineffective rate is 5%.

The invention discloses a composition. The present invention relates to a composition comprising a garlic extract standardized to contain not less than 0.3% w / w S-allylcysteine, a beet extract standardized to contain not less than 2% w / w nitrate, a nigella margarita extract standardized to contain 0.1% w / w to 5% w / w thymoquinone, 0.01% to 10% w / w thymoquinone, about 20% to 95% w / w fatty acid, about 0.001% to 3% w / w alpha-hedeine or hederagenin, and a Terminalia arjuna extract standardized to contain 3% w / w Terminalia arjuna glucoside for use as a prostaglandin transporter inhibitor. The invention also discloses application of the composition in treatment and management of hypertension and cardiovascular complications.

The invention relates to the technical field of hair nourishing and caring, and discloses hair nourishing and caring powder, which comprises the following raw materials in parts by weight: 60-80 partsof olive oil, 30-40 parts of yolk oil, 15-25 parts of sodium hydroxide, 40-60 parts of deionized water, 5-10 parts of degreased goat milk, 15-25 parts of liquorice, 10-20 parts of radix stemonae, 10-20 parts of semen nigellae, 8-16 parts of peach kernels, 6-12 parts of ocimum basilcum, 5-15 parts of black sesame, 6-10 parts of semen brassicae, 3-6 parts of pseudo-ginseng, 3-5 parts of polygonum multiflorum, 1-2 parts of ginger juice and 3-6 parts of compound essential oil. The invention further discloses a preparation method of the hair nourishing and caring powder. The hair nourishing and caring powder can balance scalp grease, clean hair and scalp, supplement nutrition for hair, scalp and hair follicles and effectively improve hair quality, and has good effects in the aspects of blackening hair and preventing alopecia.

The invention discloses a Xinjiang-Uygur-medicine nigella-sativa shampoo soap and a production technology thereof. The shampoo soap is prepared from nigella sativa seed oil, nigella-sativa plant ash,water, strong base, lavender essential oil and rosemary essential oil. The production technology includes the steps that 1, the nigella sativa seed oil is squeezed, a plant ash solution is prepared, and a base solution is prepared; 2, the plant ash solution and the strong base solution are mixed and added into the nigella sativa seed oil, and stirring and saponification are carried out; 3, the lavender essential oil and the rosemary essential oil are added, the saponified solution is poured into a mold, drying is carried out, and then demolding, cutting and packaging are carried out. The Xinjiang-Uygur-medicine nigella-sativa shampoo soap has the advantages that the shampoo soap has the effects of the three ingredients of the nigella sativa seed oil, the lavender essential oil and the rosemary essential oil, is capable of preventing alopecia, controlling the oil content, removing freckles, whitening the skin, removing wrinkles, tendering the skin and exciting hair regeneration, and isremarkable in hair growth and alopecia preventing effect; the odor is fragrant, hair is smooth and elegant after the shampoo soap is used, and light fragrances of the lavender essential oil and the rosemary essential oil are emitted; the making technology is scientific and simple, the working procedure is simple, and the cost is low.

The present invention is directed to composition comprising Nigella sativa (NS) oil, wherein said oil comprises thymoquinone (TQ) at a concentration of at least 2% (w / w). The composition is further characterized by having a much lower free fatty acid concentration than prior art compositions. The composition, which has anti-inflammatory activity, may be formulated for oral administration to a mammalian subject, for the purpose of preventing or treating inflammatory conditions and other disorders.

The invention discloses an ointment for treating vitiligo with good treatment effect, which relates to the technical field of traditional Chinese medicine, and mainly solves the problem that the existing medicines for treating vitiligo have poor treatment effect. The ointment comprises the following raw materials: 28-31g of flos caryophylli, 28-31g of black sesame, 49-51g of fructus psoraleae, 29-32g of Semen Nigellae, 18-22g of semen brassicae, 13-16g of Plumbago zeylanica root, 13-16g of pyrethrin root, 14-16g of egg yolk, 13-16g of carrot, and 1-3g of sesame oil. The ointment has strong pertinence, and the growth rate of melanin is fast, and the overall treatment level of vitiligo is improved; in the early stage of the use of the ointment for treating vitiligo, the external use of the ointment can promote the growth of melanin, and the vitiligo can be healed completely after three courses of treatment; the combination of photochemotherapy can shorten the course of treatment, and realize quick healing, and the effect is remarkable.

Disclosed are compositions of matter, treatments and protocols useful for reduction of number and / or activity of myeloid suppressor cells (MSC). In some embodiments the invention teaches the administration of a therapeutic combination of ingredients comprising of pterostilbene, Nigella sativa, sulforaphane, and epigallocatechin-3-gallate (EGCG) to a mammal at possessing an increased number and / or activity of said MSC in which reduction of number and / or activity is desired. In another embodiment, the invention teaches administration of said therapeutic combination to a mammal infected with viral and / or bacterial infections and / or neoplasia. In some embodiments dosage of said therapeutic combination is based on inflammatory and / or immunological parameters observed in patients.

The invention discloses a medicine composition for treating bartholinitis and a preparation method thereof, and relates to the technical field of medicaments of the obstetrics and gynecology department. The medicine composition for treating bartholinitis is prepared from lettuce seeds, machilus grifsii Hance, colla carapacis trionycis, roots and leaves of affined conehead, rhizomes of sorghumpro pinquum (Kunth) Hitehc., lip-fern, roots of long pepper, wood of largeleaf dogwood, herba rubiae yunnanensis, helwingia japonica (Thunb.) Dietr., roots of Szechwan-Yunnan sanicle, semen nigellae, dendrobe, lemons, maltose, glucuronolactone, an amino acid mixture, alpha-pinene, biotin, niacin, mineral matter and an antibacterial agent. The medicine composition is prepared according to the theory of traditional Chinese medicine in combination with clinical experience, the selected medicinal materials are reasonable in compatibility and appropriate in proportion, all the ingredients supplement one another and jointly achieve the effects of clearing away heat and toxic materials, dispersing stasis and diminishing swelling, promoting blood circulation and alleviating pain, tonifying Qi and reinforcing deficiency, resisting bacteria and diminishing inflammation, clearing away liver heat, tonifying middle-Jiao and Qi and tonifying the stomach and promoting fluid, and the medicine composition can effectively treat bartholinitis and thoroughly remove the disease and is significant in treatment effect, not likely to cause medicine resistance and small in side effect.

The invention belongs to the technical field of medicines, and particularly relates to a traditional Chinese medicine composition for treating tumors and a preparation method thereof. The traditional Chinese medicine composition for treating tumors is prepared from the following raw material components: fructus lycii, sea buckthorn seeds, nigella glandulifera seeds, semen armeniacae amarae, fructus cannabis, perillaseed, wheat germ, borage and linseed. According to the traditional Chinese medicine composition for treating the tumors, all the raw material components are selected from seeds of medicinal and edible plants, and the components contain rich essential fatty acids, vitamins, celluloses, minerals and the like which are required by a human body and directly act on human cells, so that the functions of the human body are self-repaired to be in a healthy state. Through the synergistic compatibility effect of the raw material components, the omega-3 fatty acid, omega-6 fatty acid and omega-9 fatty acid in the composition reach the balance required by a human body, and the composition can directly act on cells and help cell membranes maintain normal fluidity and elasticity, so that the immune system of the body is automatically repaired, and the effect of treating tumors is achieved.

The invention relates to a natural hair growth promoting liquid and a preparation method thereof. The liquid is prepared from Semen Nigellae, Fructus Phyllanthi, Semen Melo, Semen Brassicae Junceae, Semen Myristicae, Herba Rutae, and Fructus Zanthoxyli by pulverizing, adding water, extracting volatile oil, adding water or ethanol to residue and extracting to obtain extract, filtering, concentrating, and mixing with the volatile oil. The natural hair growth promoting liquid developed on basis of Uyghur medicinal basic theory has the advantages of natural product for treating alopecia, definitecurative effect, no toxic / side effect and irritation, is especially suitable for seborrheic alopecia, and provides convenience for alopecia patients.

Disclosed are compositions of matter, treatments and protocols useful for prevention of SARS-CoV-2 infection, as well as inhibition of viral propagation and acceleration of viral cure. In some embodiments the invention teaches the administration of a therapeutic combination of ingredients comprising of metformin, pterostilbene, nigella sativa, sulforaphane, and epigallocatechin-3-gallate (EGCG) to a mammal at risk of infection with SARS-CoV-2. In another embodiment, the invention teaches administration of said therapeutic combination to a mammal infected with said SARS-CoV-2. In some embodiments dosage of said therapeutic combination is based on inflammatory and / or immunological parameters observed in patients with COVID-19.

The invention is directed to the utilization of pterostilbene, and / or nigella sativa extract, and / or sulforaphane, and / or Epigallocatechin gallate (EGCG) alone or in combination, for the prevention of pathological coagulation. In on embodiment a composition containing all four ingredients is administered to a patient at risk of hypercoagulation in order to prevent aberrant expression of pro-coagulation molecules and / or induce expression of molecules known to suppress coagulation. In one embodiment the invention teaches administration of pterostilbene, thymoquinone, sulforaphane, and EGCG as a means of decreasing expression of tissue factor.

The invention discloses a traditional Chinese medicine for promoting ovulation and a preparation method of the traditional Chinese medicine. The traditional Chinese medicinal medicine is prepared by taking the following raw materials in proportions by weight: 15 to 25 parts of fiveleaf akebia fruit, 15 to 25 parts of black bean, 10 to 20 parts of radix acanthopanacis senticosi, 10 to 20 parts of semen sesami nigrum, 5 to 15 parts of towel gourd vegetable sponge, 5 to 15 parts of selaginella tamariscina, 4 to 12 parts of semen juglandis, 4 to 12 parts of colla corii asini, 2 to 10 parts of fructus citri, 2 to 10 parts of radix paeoniae alba, 2 to 8 parts of rhizoma corydalis, 2 to 8 parts of semen nigellae and 1 to 5 parts of human placenta. The traditional Chinese medicinal medicine for promoting the ovulation, which is provided by the invention, adopts common traditional Chinese medicinal materials as the raw materials, is scientific in formula, low in cost, convenient to take, obvious in curative effect and free of toxic and side effects, has the functions of benefiting qi for promoting production of blood, dispersing stagnated liver qi for relieving qi stagnation, tonifying kidney, strengthening spleen, eliminating phlegm and freeing channels, and can obtain ideal ovulation rate and pregnancy rate.

A composition enriched with bisdemethoxycurcumin standardized to contain 20-80% w / w bisdemethoxycurcumin, 10-35% w / w demethoxycurcumin and 10-50% w / w curcumin. More specifically the invention discloses the potential of a composition comprising 20-80% w / w bisdemethoxycurcumin, 10-35% w / w demethoxycurcumin and 10-50% w / w curcumin in the management of nephrotoxicity in mammals. The composition further comprises a Nigella sativa extract standardised to contain not less than 2% w / w thymoquinone and about 0.01%-10% w / w thymohydroquinone.

The invention provides skin bacteriostatic cream and a preparation method thereof. The preparation method comprises the following steps: dissolving: dissolving beeswax in a water bath kettle at the temperature of 60 DEG C for later use; stirring the vegetable oil: pouring olive fruit oil, sesame oil, cultivated nigella nigra seed oil, clove essential oil, lithospermum oil, sea buckthorn fruit oil, pistachio oil, walnut oil, pomegranate seed oil and shea butter into an interlayer stirring pot with a heating function, heating to 40 to 50 DEG C while stirring, stirring for 6 to 8 hours, and keeping the temperature and standing for 2 hours; stirring the mixture: pouring the dissolved beeswax into an interlayer stirring pot, continuously stirring for 2H, reducing the temperature to 35 DEG C, slowly adding parachlorometaxylenol, and uniformly stirring; and filtering and filling: filtering the fully stirred mixture, and filling to obtain a finished product. The skin antibacterial cream is very suitable for the skin of people living in dry climate in Xinjiang due to high oil content, is rich in vitamin E grease, not only nourishes the skin, but also forms a layer of protective film on the skin, shrinks, moistens, inhibits bacteria and relieves itching.

The invention discloses a traditional Chinese medicine for treating alcoholism. The traditional Chinese medicine is prepared from the following medicinal materials in parts by weight: 10-19 parts of ophiopogon root, 10-24 parts of aster poliothamnus, 3-11 parts of primula obconica, 2-9 parts of fructus broussonetiae, 20-29 parts of galangal, 5-12 parts of semen nigellae, 1-8 parts of yarrow, 0-10 parts of semen dolichoris album, 10-20 parts of semecarpus, 2-7 parts of beautyberry leaf, 5-9 parts of orange peel, 3-10 parts of coriander fruit and 10-18 parts of emblic leafflower fruit. The traditional Chinese medicine disclosed by the invention is appropriate in compatibility of the selected medicinal materials and has double effects of treatment and conditioning; the traditional Chinese medicine is natural, so that toxic or side effects of chemicals are avoided and the traditional Chinese medicine can be taken safely; the traditional Chinese medicine has an obvious effect on alleviating hangover, and is an ideal health-care preparation for treating alcoholism, excessive drinking and alcoholic liver disease; the traditional Chinese medicine is a pure traditional Chinese medicine preparation which is non-toxic to a human body and particularly to the liver and has an obvious curative effect; and the traditional Chinese medicine composition is simple in preparation and is non-toxic.

The invention discloses an external application preparation for treating leucoderma. The external application preparation is prepared from, by weight, 11-16 parts of paniculate swallowwort roots, 9-13 parts of porana flowers, 6-13 parts of small goosefoot, 10-14 parts of dry lotus, 8-15 parts of pararuellia delavayana, 6-12 parts of semen nigellae, 10-15 parts of artemisia anomala, 8-14 parts of gourian clematis roots, 7-13 parts of tribulus terrestris, 9-12 parts of walnut citri reticulatae viride, 10-16 parts of eupatorium japonicum thunb, 7-14 parts of common adenostema herbs and 6-9 parts of stiff silkworms. The external application preparation for treating the leucoderma can effectively stimulate proliferation of melanocytes, promote formation of growth factors for melanocyte proliferation and differentiation, recover the damaged melanocytes, and achieve the purpose of curing the leucoderma.

The invention provides a composition comprising oil obtained from Nigella sativa seeds and one or more surface-active agents. Preferably, the concentration of thymoquinone in the composition is at least 2% (w / w), wherein the concentration of the surface-active agent(s) is at least 0.2% (w / w), and wherein the one or more surface-active agents are selected from the group consisting of D-α-Tocopherol polyethylene glycol succinate (TPGS), lecithin and isolecithin. The invention also provides a method for preventing and / or treating pathological states and disorders associated with obesity, comprising the steps of administering a composition of the invention to a human subject.