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The application of Nigella sativa extract as a drug for the preparation of adjuvant arthritis

A technology for adjuvant arthritis of Nigella cumulus and adjuvant arthritis, which is applied in the field of Nigella cumulus extract and can solve the problems of high toxicity and side effects

Active Publication Date: 2020-10-30
中国人民解放军新疆军区药品仪器检验所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention provides a kind of Nigella nigellae extract as an application in the preparation of adjuvant arthritis medicine, which overcomes the deficiencies in the prior art, and can effectively solve the toxic and side effects of existing western medicines for treating rheumatoid arthritis Larger problem; the present invention discloses for the first time the composition of Nigella cumulus extract, Semen Nigella tumosa flavonoids, volatile oil of Semen Nigella tumosa and the flavonoids and volatile oil of Semen Application of preparation of medicine for treating adjuvant arthritis

Method used

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  • The application of Nigella sativa extract as a drug for the preparation of adjuvant arthritis
  • The application of Nigella sativa extract as a drug for the preparation of adjuvant arthritis
  • The application of Nigella sativa extract as a drug for the preparation of adjuvant arthritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Example 1: The application of the Nigella sativa extract as a drug for the preparation of adjuvant arthritis. The nigella seed extract is a plant extract, and when used as a drug for treating adjuvant arthritis and other diseases, its toxicity is far less than that of the conventionally used drug (dexamethasone) for this disease.

Embodiment 2

[0015] Example 2: As an optimization of the above example, the extract of Nigella tumefaciens is flavonoids from Nigella tumefaciens.

Embodiment 3

[0016] Example 3: As an optimization of the above-mentioned Example 1, the difference from Example 2 is that the extract of Nigella tumefaction is the volatile oil of Nigella tumefaction.

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Abstract

The invention relates to the technical field of application of Nigella tumefica extract, and relates to the application of the extract of Nigella cumin in the preparation of adjuvant arthritis medicine. The present invention discloses for the first time the application of the flavonoids of Nigella tumosa, the volatile oil of Nigella tumosa and the composition of the flavonoids of Nigella tumosa and the volatile oil of Nigella tumosa as the preparation of adjuvant arthritis medicine. Experiments show that the flavonoids of Nigella tumosa, the volatile oil of Nigella tumosa and the composition of the flavonoids of Nigella cumulatus and the volatile oil of Nigella tumosa have a better therapeutic effect on adjuvant arthritis, and have obvious inhibitory effects on adjuvant arthritis. The role of immune function, it is particularly worth mentioning that the composition of Nigella tumefaction flavonoids and volatile oil of Nigella tumefaction has comparable therapeutic effects on adjuvant arthritis and dexamethasone on the disease.

Description

technical field [0001] The invention relates to the technical field of application of Nigella tumefaction extract, and relates to the application of the extract from Nigella tumefaction as a medicine for treating adjuvant arthritis. Background technique [0002] Nigella glandulifera belongs to Ranunculaceae Nigella genus Nasturtium subfamily plants, in which there are 3 kinds of medicinal plants, namely nigella glandulifera seeds (NGS), also known as nigella glandulifera, nigella glandulifera Grass (Nigella Sativa), also known as Nigella Damascena, and Nigella Damascena (Wang Zhimin, Ren Qian, Guo Ping. A comparative study of the technical requirements of the US FDA "Plant Drug Industry Guide" and the technical requirements of new traditional Chinese medicines in my country[ J]. World Science and Technology Modernization of Traditional Chinese Medicine, 2011, 3(5): 46-49). Nigella tumefica is widely distributed in the Mediterranean region (Egypt, Pakistan, etc.), and Nigella ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61P19/02A61P37/02A61P11/00
CPCA61K36/71A61K2300/00
Inventor 耿东升张宏涛陈雪莲曹园
Owner 中国人民解放军新疆军区药品仪器检验所
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