234 results about "Microbiological material" patented technology

A needleless valve assembly includes a needleless connector having a housing with an inlet end with an inlet opening and an outlet end with an outlet opening, and a valve disposed in the housing to control passage between the openings. The assembly also includes a collar having an exterior surface and an interior surface, and a first end with a collar opening communicating between the interior surface and the exterior surface and a second end moveably attached to the housing. Further, the assembly includes a barrier disposed across the collar opening with a slit therethrough and including an anti-microbial material. The collar is moveable relative to the housing so that the inlet end of the housing depends past the exterior surface of the collar through the slit in the barrier. A kit may include the assembly and a catheter having a first end attached to the outlet opening.

An antimicrobial composition is formed from about 5 to about 25 wt % of an antimicrobial formulation and about 75 to about 95 wt % of a silicone resin. The antimicrobial formulation is formed from about 60 to about 95 wt % of an antimicrobial material, about 1 to about 30 wt % calcium chelator, about 0.001 to about 0.25 wt % pigment, and about 0.5 to about 3.5 wt % lubricant. The silicone resin may be a dispersion of about 40 to about 60 w / v % of an RTV silicone resin in a solvent, a liquid silicone resin, or a solid silicone resin. An antimicrobial coating may be formed on the surface of an article by applying an antimicrobial composition to the article and permitting the solvent to evaporate. It may also be formed by making a mixture of about 5 to about 12 wt % of an antimicrobial formulation and about 88 to about 95 wt % of a liquid or solid silicone resin and molding, overmolding, or extruding the article from the compounded mixture.

A catheter having features configured to provide a substantially uniform flow rate of a fluid exiting the catheter and also exhibits anti-microbial properties. The uniform flow rate features may include one or more of a flow restricting membrane or flow restricting component within an infusion section of the catheter. In other arrangements, exit holes defining the infusion section of the catheter may be configured to provide the desired uniform flow rate over the length of the infusion section. Furthermore, the catheter also includes anti-microbial properties to inhibit the growth of microbes on or within the catheter and, preferably, to inhibit microbe growth in an anatomical region surrounding the catheter. The desired anti-microbial properties may be provided by an anti-microbial layer, anti-microbial materials dispersed within the material from which components of the catheters are constructed, or a combination of anti-microbial layers and embedded anti-microbial materials. In some arrangements, one or more portions of the catheter may be bio-absorbable.

A system for the rapid analysis of microbiological parameters includes a specimen container for containing a liquid sample, a housing having an enclosable chamber shaped for receiving the specimen container, an incubating system mounted within the housing for incubating microbiological materials within the liquid sample, and a spectrophotometer system mounted within the housing for measuring light absorbed, emitted or scattered by the liquid samples as the microbiological materials are incubated by the incubating system over time. The specimen container is filled with a liquid sample to be tested and mixed with a reagent that provides a detectable parameter, and placed inside the apparatus. The incubation system heats and maintains the temperature of the liquid sample within a preset range while the spectrophotometer system propagates light within the specimen container, and monitors and records changes in the light as the light propagates through the container. A continuous non-intrusive monitoring and recording of the test parameter is achieved as the incubation progresses. Any significant deviation of the signal output is an indication of presence of the detectable parameter, while the time taken to reach the significant deviation provides quantification of the microbiological parameter under investigation.

Compositions having antimicrobial activity contain surface functionalized particles comprising an inorganic copper salt which has low water solubility. These types of inorganic salts may also be introduced in porous particles to yield antimicrobial compositions. The compositions may optionally comprise additional antimicrobial agents, salts with high water solubility, organic acids, salts of organic acids and their esters. The compositions may be added to various fluids used in the petroleum extraction industry, or used as coatings on components used in this industry. These antimicrobial materials may be used for reducing both anaerobic and aerobic bacteria and are also useful for reducing corrosion of ferrous components caused by anaerobic bacteria. Although such compositions may be used for any antimicrobial application, and some of the other important uses of these compositions are in wound care, personal care and waste processing.

The invention is directed to efficient methods for depositing highly adherent anti-microbial materials onto a wide range of surfaces. A controlled cathodic arc process is described, which results in enhanced adhesion of silver oxide to polymers and other surfaces, such as surfaces of medical devices. Deposition of anti-microbial materials directly onto the substrates is possible in a cost-effective manner that maintains high anti-microbial activity over several weeks when the coated devices are employed in vivo.

An antimicrobial composition is formed from about 5 to about 25 wt % of an antimicrobial formulation and about 75 to about 95 wt % of a silicone resin. The antimicrobial formulation is formed from about 60 to about 95 wt % of an antimicrobial material, about 1 to about 30 wt % calcium chelator, about 0.001 to about 0.25 wt % pigment, and about 0.5 to about 3.5 wt % lubricant. The silicone resin may be a dispersion of about 40 to about 60 w / v % of an RTV silicone resin in a solvent, a liquid silicone resin, or a solid silicone resin. An antimicrobial coating may be formed on the surface of an article by applying an antimicrobial composition to the article and permitting the solvent to evaporate. It may also be formed by making a mixture of about 5 to about 12 wt % of an antimicrobial formulation and about 88 to about 95 wt % of a liquid or solid silicone resin and molding, overmolding, or extruding the article from the compounded mixture.

A system is provided for regulating a flow of oxygen to a patient where the system may include an oximeter for measuring the patient's blood oxygen level and / or heart rate; a controller for determining a desired oxygen flow rate based on the patient's blood oxygen level and / or heart rate, and generating a control signal representative of the desired oxygen flow rate; an oxygen flow regulator for dynamically regulating a flow rate of oxygen supplied to the patient responsive to the control signal provided by the controller; an oxygen delivery device; and a transmitter for wirelessly communicating with an electronic medical records system. The oxygen flow regulator may receive oxygen from an oxygen bottle, oxygen mixer, a wall oxygen supply of a healthcare facility, or an oxygen concentrator. One or more of the components of the system may be treated with an antimicrobial material.

Specific transfer methods and articles to impart a metal-ion based antimicrobial finish to recipient textile surfaces. Such treatments preferably comprise silver ions, particularly as constituents of inorganic metal salts or zeolites. In particular, the inventive method involves the application of a solid, inorganic antimicrobial material to a donor substrate (such as a dryer sheet), and the subsequent placement of such a substrate within a tumble drying machine containing textile fabrics and operating the machine. The donor substrate, upon contact with the recipient textile fabrics, transfers antimicrobially effective amounts of the metal-ion based compounds to such recipient fabrics thereby imparting at least a temporary antimicrobial finish over at least a portion of such fabrics. The donor substrates, with either the antimicrobial compound alone or mixed with standard tumble dryer additives (such as perfumes, fabric softeners, fiber lubricants, and the like) are also contemplated within this invention.

An intravenous connector is provided having a valve body having first end configured to receive a syringe for administering medicine to a patient; a spike element having a tapered hollow spike terminating in a tip at a first end and having a second end configured for attaching to an intravenous tube, the spike element secured in the valve body such that the tip is disposed proximate the first end of the valve body and the second end of the spike element is located at a second end of the valve body; and a pliable seal member disposed in the valve body around the tapered hollow spike and exposed at the first end of the valve body. An antimicrobial material comprising a silane quaternary ammonium salt is incorporated on or within the seal member and is coated on the valve body and the spike element.

The invention describes a usage of a heteroatom doped water-soluble carbon quantum dot serving as a photosensitizer in an antimicrobial material. Various types of heteroatom doped water-soluble carbon quantum dots contain one or more of such heteroatoms as N, S, Si, Se, P, As, Ge, Gd, B, Sb and Te, and the absorption spectrum wavelength of the heteroatom doped water-soluble carbon quantum dot is 300-850 nm. As shown in a research, the heteroatom doped water-soluble carbon quantum dots can efficiently generate active oxygen under the irradiation of visible light, so that the heteroatom doped water-soluble carbon quantum dot has a huge development potential in the application field of photodynamic (PDT) sterilization and disinfection.

A method is provided for depositing a hard wear resistant surface onto a porous or non-porous base material of a medical implant. The wear resistant surface of the medical implant device may be formed by a Laser Based Metal Deposition (LBMD) method such as Laser Engineered Net Shaping (LENS). The wear resistant surface may include a blend of multiple different biocompatible materials. Further, functionally graded layers of biocompatible materials may be used to form the wear resistant surface. Usage of a porous material for the base may promote bone ingrowth to allow the implant to fuse strongly with the bone of a host patient. The hard wear resistant surface provides device longevity, particularly when applied to bearing surfaces such as artificial joint bearing surfaces or a dental implant bearing surfaces. An antimicrobial material such as silver may be deposited in combination with a metal to form an antimicrobial surface deposit.