59 results about "Metaphysis" patented technology

The humeral portion of a shoulder prosthesis includes a diaphyseal component configured for fixation within the humerus, a metaphyseal component, configured for removable implantation within the metaphysis of the humerus, and an engagement mechanism for removably engaging the two components. The metaphyseal component can initially include a convex articulating surface that can be replaced with a concave surface during the shoulder arthroplasty procedure or in a subsequent revision surgery. The metaphyseal component can also include a feature to facilitate removal of the component from the bone once it has been disengaged from the diaphyseal component.

A medical implant plate including at least two sets of apertures through an elongated shaft body to individually accommodate and orient set screws or pegs at various angles that may be selected depending on application, i.e., the apertures don't have fixed angled, but allow for a range of angles. Once the screw has been locked, the device becomes a fixed angled device. The screws or pegs laterally spaced relative to each other to resist torsion and to secure the plate against dislodgement. The body also includes a flared-end portion that accommodates and extends partially onto a metaphysis of a tubular bone of the hand while maintaining a low-profile to avoid soft-tissue irritation. The flared-end portion that extends on to the metaphysis does NOT have holes for screws but serves as a buttress. Screws that extend into the metaphysis come from the three holes located along the slightly angled portion of the plate.

An implant for shoulder arthroplasty includes a stem and optionally a head component or a cup component. The stem is sized and shaped to fit into an intramedullary canal of the humerus. The proximal portion of the stem has a concave taper and the distal portion of the stem has a taper. The distal taper includes an anterior-posterior taper and a medial-lateral taper. The shape of the stem loads the metaphysis of the humerus with a greater load than the load applied to the diaphysis of the humerus.

A humeral prosthetic head has a non-spherical articulation surface coupled with an intermediate component connecting the head and the humerus, the intermediate component connected to the epiphysis, metaphysis, or diaphysis, or to one or more additional components connected to the humerus. The intermediate portion provides for axial and angular offset of the head with respect to a connection to the humerus, using a curvilinear tapered engagement.

A method for arthroplasty includes using a self-locking prosthesis that has a member structured to transfer a load produced by the weight of a patient to a bone. An expandable bone-locking portion that is integral to the member includes a shape-memory material and expands to produce a locking force. A portion of the bone is removed to form an aperture in the bone. The bone-locking portion is inserted into the aperture, and a temperature increase causes a change from a contracted state to an expanded state resulting in expansion of the bone-locking portion so as to contact the inner surface. The expanding is sufficient to create a locking force at the junction between the inner surface and the bone-locking portion of the prosthesis and the majority of the locking force is applied at or above the metaphysis. The length / width ration of the prosthesis may be less than or equal to 5. The resulting reconstructed long-bone may have improved primary and long-term stability.

The present invention is an improved unique odd angle internal fixation device for both a transverse and longitudinal fracture located at the junction of the metaphysis and diaphysis of a long bone such as the proximal humerus. The improved odd angle internal fixation device includes an elongated lag screw and a rectangular shaped guide plate having multiple holes throughout the plate to host pins and screws and four tips on the front side of the plate. A lag screw with a cylindric head having a hexagonal cavity introduced through the diaphyseal segment of the fracture at three angles, 90, and 150 and 160 degrees, cross fixing the respective bone longitudinal and transverse fracture line and settling in the depth of the epiphysis. An additional locking screw is introduced on the top of the lag screw head to securely lock the lag screw after being settled into the epiphysis. The guide plate serves as a guide for the lag screw and allows the engagement of the head of the lag screw to the inner wall of its short barrel portion. The engagement would cause the guide plate which is attached to the barrel, to be compressed against the diaphyseal cortex as the lag screw advances deeper into the epiphysis at said three angles.

A tissue engineering cartilage construction method using bone matrix gelatin which comprises, using cartilage cell for isolated culture or base material stem cell for isolated culture to evoke cartilage cell i.e. seed cell, fetching New Zealand rabbit or human embryon os longum and metaphysic trabecular bone to construct bone matrix gel BMG, inoculating the seed cells harvested through isolated culture onto cortex bone or cancellous bone BMG for extracorporal culture.

The invention discloses a double-nail-hook metaphysis pressurizing fixing device which comprises a first fixing part, a second fixing part and a connecting part. The connecting part is used for connecting the first fixing part and the second fixing part. The first fixing part comprises two strip-shaped objects. The strip-shaped objects are used for penetrating through the fracture part of the metaphysis and being inserted into the backbone to be fixed. The connecting part is in a forked strip-shaped hook shape attached to the surface of the bone. Forked strips of the connecting part and the strip-shaped objects of the first fixing device are connected in a one-to-one corresponding mode. A plurality of pressurizing fixing holes are formed in the second fixing part. Pressurizing screws penetrate through the pressurizing fixing holes so that the second fixing part can be fixed to the backbone connected with the metaphysis. The pressurizing fixing device is convenient to take out, low in cost, and beneficial for healing the fracture part and preventing secondary injuries to normal bone tissue.

The invention discloses a method for performing EBM metal 3D printing on a personalized human body thighbone prosthesis sleeve. The method includes the steps that encrypted CT scanning is performed on the upper middle section of a metaphysis prosthesis part, and CTdicom data are input into Mimics software to reconstruct a grid model; surface reconstruction and smoothing processing are performed on the grid model; post-modification is performed on the bone three-dimensional grid model based on the joint prosthesis design concept; a personalized joint prosthesis three-dimensional model is generated through surface reconstruction and designing; the shape of a personalized joint prosthesis is adjusted through finite element analysis; the three-dimensional model of the implant is input into a rapid prototyping machine and printed through EBM RP technology metal 3D printing. The shape of the printed and manufactured finished product can be completely matched with that of the medullary cavity of the distal femoral metaphysic of every patient, the personalized thighbone prosthesis can be knocked to be implanted just through a few intra-operative medullary cavity files, and good initial fixation and long-time biological fixation can be achieved.

Devices and systems for repairing bone fractures and more specifically a fracture repair plate that provides for fixation of a metaphysis to the diaphysis of a long bone, for instance a fracture between the proximal humerus and the diaphysis of the humerus. The fracture repair system includes an implantable repair fracture repair plate and a bone anchor for fixing the fracture repair plate to a bone. In one embodiment, the fracture repair plate may also be adapted to serve as an anchor for a suture. The fracture repair system may also include a fracture reduction mechanism attachable to the fracture repair plate for imparting a controlled translational movement between two bone segments along a plane that lies substantially parallel to the surface of the bone to which the fracture repair plate is attached and substantially parallel to the longitudinal axis of the bone shaft.

The invention discloses a method for preparing a novel individual degradable artificial intraosseous stent, which belongs to the technical field of biomedicine. The method comprises the following steps of making a light-cured resin mold of which the form is consistent with the marrow cavity of a tubular bone massive comminuted fracture segment by using a rapid forming technology; and pouring an artificial intraosseous stent by using a compound material. The stent has the advantages of easiness in operating, reliable curative effect, high bone healing speed and small quantity of complications when applied to operation of tubular bone massive comminuted fractures, can be particularly applied to treatment of comminuted fractures of tubular bone metaphysis, and has very high potential clinical application value.

Devices and systems for repairing bone fractures and more specifically a fracture repair plate that provides for fixation of a metaphysis to the diaphysis of a long bone, for instance a fracture between the proximal humerus and the diaphysis of the humerus. The fracture repair system includes an implantable repair fracture repair plate and a bone anchor for fixing the fracture repair plate to a bone. In one embodiment, the fracture repair plate may also be adapted to serve as an anchor for a suture. The fracture repair system may also include a fracture reduction mechanism attachable to the fracture repair plate for imparting a controlled translational movement between two bone segments along a plane that lies substantially parallel to the surface of the bone to which the fracture repair plate is attached and substantially parallel to the longitudinal axis of the bone shaft.

The invention provides a proximal tibia outer side locking plate. The proximal tibia outer side locking plate comprises a main body component and a connecting plate component, wherein the main body component is used for fixing a proximal tibia outer side; the main body component comprises a head part, a rod part and a connecting part for connecting the head part with the rod part; the head part wraps and fixes an outer side column of a proximal tibia platform; the rod part is attached to the outer side surface of a tibial shaft and is fixed; the connecting part is adhered to a tibia surface and is bent; the connecting plate component is connected with the head part and is used for fixing a connecting plate component of a rear side column of the proximal tibia platform. By the main body component, the outer side of a tibia is fixed; by the design of the connecting plate component, fixation to the rear side column of the proximal tibia platform is enhanced, so that the proximal tibia outer side locking plate can be used in surgeries such as proximal tibia fracture, metaphysis fracture, intra-articular fracture and periprosthetic fracture. In addition, the head part of the main body component warps the outer side column of the proximal tibia platform. Compared with an existing curved-surface bone fracture plate, the proximal tibia outer side locking plate is fixed firmly and reliably.

The invention discloses a method for fixing a bone morphogenetic protein-2 (BMP-2) with a decalcified bone matrix. By using the decalcified bone matrix prepared by the metaphysis of pork hind leg bones as an object, the method comprises the following steps of: loading a BMP-2 solution at the concentration of 1 mu g per mu L to the decalcified bone matrix; placing into a microwave synthesizer, and processing for 30 minutes at the microwave power of 500 watts and reaction temperature 37 DEG C to fix the BMP-2 on the decalcified bone matrix; and putting the decalcified bone matrix in a 3 percentchitosan solution for 5 minutes, then taking the decalcified bone matrix out, and drying at the temperature of 37 DEG C. By adoption of the method provided by the invention, the fixation and combination of the BMP-2 and the decalcified bone matrix are stable, a fixing effect is good, the release speed of the BMP-2 is reduced, and the utilization ratio of the BMP-2 is improved; and the method has a higher practical application value in the field of medicine.

A system for sizing the resected surface to provide metaphyseal referencing and to properly guide a tool into a central portion of the canal in the diaphysis. The system can include a sizing feature to approximate the size of the metaphysis. The system can also include a base configured to contact the metaphysis and a guide feature configured to guide a tool along a central portion of the canal in the diaphysis.

Provided is a method and an apparatus for extracting an edge of a distal radius metaphysis. The method includes: setting a region of interest including a distal radius in an X-ray image; setting a potential energy distribution of the region of interest by using a gradient of gray levels; setting a temporary edge adjacent to both sides of a distal radius metaphysis and a side of an epiphysis in the region of interest; and extracting a detailed edge of the distal radius metaphysis having minimum energy by adjusting the set temporary edge using a metropolis annealing technique.

The invention relates to a DNA library for detecting and diagnosing pathogenic genes of skeletal development disorders through a targeted high-throughput sequencing technology and application thereof. The library comprises 507 pathogenic genes of skeletal development disorders. According to the invention, 507 pathogenic genes of skeletal development disorders are preferably selected, a probe pool is designed, a target region library for 507 pathogenic genes of skeletal development disorders is established, and the library utilizes the high-throughput sequencing technology for sequencing to find pathogenic mutations, thereby providing genetic and molecular biological bases for clinical diagnosis. The DNA library provided by the invention has the characteristics of accuracy, rapidness, flexibility and low cost. The 507 genes involved in the invention include pathogenic genes of genetic diseases with skeletal development disorders as clinical manifestations, such as collagen dysplasia, metaphysic dysplasia, osteogenesis imperfecta and bone density reduction, mucopolysaccharide storage disease, cartilage dysplasia and the like, and have important significance and clinical value for diagnosis, differential diagnosis and accurate treatment of skeletal development disorders.

An implant for shoulder arthroplasty includes a stem and optionally a head component or a cup component. The stem is sized and shaped to fit into an intramedullary canal of the humerus. The proximal portion of the stem has a concave taper and the distal portion of the stem has a taper. The distal taper includes an anterior-posterior taper and a medial-lateral taper. The shape of the stem loads the metaphysis of the humerus with a greater load than the load applied to the diaphysis of the humerus.

The invention discloses a metal spicule and relates to an instrument used in an orthopedic operation. A threaded part is arranged on the front portion of a cylindrical rod body of the metal spicule, and a planar clamping part is arranged on the outer circumference of the rear end of the rod body; the threaded part with the cylindrical outer circumference being the same as that of the rod body is arranged on the front portion of the rod body, the outer diameter of the root of each thread on the threaded part becomes larger gradually from front to back, and the height of each thread becomes smaller gradually from front to back; a hydroxylapatite coating is arranged on the outer circumference of the threaded part; radial blind holes which extend towards the central axis of the rod body are formed in the portions, between the threads on the upper portion of the threaded part, of the spiral circumferential surfaces of the roots; an antibiotics coating is arranged on the outer circumference of the middle of the rod body. The metal spicule is high in holding force, capable of preventing inflammation of the skin of a human body, and suitable for osteoporotic patients or the metaphysis.

The invention discloses an intramedullary nail special for children, which comprises a nail sleeve and a nail core, the far end of the nail core is provided with a first locking hole, the far end of the nail core is driven into the femoral marrow and penetrates through the growth plate at the lower end of the femur, a kirschner wire or a screw is driven at the epiphysis to enter the first locking hole to lock the nail core, the far end of the nail sleeve is driven into the femoral marrow from the greater trochanter at the proximal end of the femur to reach the metaphysis without passing through the growth plate, the nail sleeve is sleeved on the nail core, the near end part of the nail sleeve is arranged outside the femur, a second locking hole is formed in the nail sleeve, and a screw is screwed into the second locking hole through the skin to lock the nail sleeve. The intramedullary nail is applied to the distal femoral fracture of children, can be extended, prevented from rotating and locked, and can fix the fracture and retain the normal growth function of the growth plate.

The present invention relates to an internal bone plate fixation device (1) for use as a means of synthesis in anatomical regions or epiphysis / metaphysis with poor coating of soft tissues, of the type comprising a bone plate (2) that is bilobate or having eight-like shape, comprising a pair of portions (23, 24) adapted to be respectively associated to the epiphysis and to the metaphysis of a bone and joined by a central portion (15) and in each of which is formed at least one through hole (3, 4) to receive a corresponding screw (5) for fixing to the bone. Advantageously, the bone plate (2) is flat with almost constant thickness and is delimited by opposite surfaces (6, 7) parallel with a single recess (8) or notch that is transversal to the longitudinal axis of bone plate (2) formed on only one (6) of said surfaces (6, 7), with the thickness (s) of the plate being less than a ninth of its maximum longitudinal extension (L).

The invention relates to a meniscus bracket and a preparation method thereof. The preparation method comprises the following steps: taking heterogeneous or allogeneic cancellous bone of femur or tibial metaphysis, removing surrounding attached tissues, and using an electric pendulum saw to cut out Cancellous bone slices with a predetermined thickness are soaked in distilled water after cleaning; the cancellous bone slices are processed into ring-shaped scaffolds after decalcification, fat-removing and protein removal; finally, the ring-shaped scaffolds are freeze-dried at -20°C and irradiated with cobalt 60 Sterilize and store at -80°C for more than 2 weeks to obtain a meniscus scaffold. The meniscal scaffold made of demineralized cancellous bone in the present invention has biological activity and can promote the adhesion and proliferation of cells; and the annular shape also increases the surface area, which is conducive to the full exchange of substances between cells and culture medium, and reduces Apoptosis, thereby increasing the number of cells.

The invention relates to a method for preparing a PLGA (polylactic-co-glycolic acid) modified biological factor microsphere supported bone substituted material. The method comprises the following steps: 1, preparing a drug-loaded chitosan microsphere from carboxymethyl chitosan, recombinant human adiponectin, recombinant human bone morphogenetic protein and sodium tripolyphosphate; 2, modifying the metaphysis, serving as a bone raw material, of a newborn calf articular head or tibia with a modifying agent, calcining the modified bone raw material at 800-1100 DEG C to completely remove the immunizing antigenicity to obtain modified calcined bone powder; and 3, preparing the PLGA modified biological factor microsphere supported bone substituted material from PLGA, the modified calcined bone powder and the drug-loaded chitosan microsphere. The PLGA modified biological factor microsphere supported bone substituted material has certain morphological and mechanical strength, and can be used for sustainably releasing biological active factors for promoting bone formation and locally releasing calcium and phosphor ions on a bone defect position.

A tissue engineering cartilage construction method using bone matrix gelatin which comprises, using cartilage cell for isolated culture or base material stem cell for isolated culture to evoke cartilage cell i.e. seed cell, fetching New Zealand rabbit or human embryon os longum and metaphysic trabecular bone to construct bone matrix gel BMG, inoculating the seed cells harvested through isolated culture onto cortex bone or cancellous bone BMG for extracorporal culture.