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158 results about "Ion binding" patented technology

Ion binding polymers and uses thereof

The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising potassium binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and / or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hyperkalemia, such as hyperkalemia caused by renal failure and / or the use of hyperkalemia causing drugs.
Owner:VIFOR INT AG

Ion binding polymers and uses thereof

The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising potassium binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and / or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hyperkalemia, such as hyperkalemia caused by renal failure and / or the use of hyperkalemia causing drugs.
Owner:VIFOR (INT) AG

Method for detecting heavy metal by utilizing molecular device based on graphene electrode

The invention discloses a method for detecting heavy metal and a DNAzyme monomolecular connection device based on a graphene electrode special for same. A manufacturing method for the DNAzyme monomolecular connection device comprises the following steps of: 1) constructing a graphene transistor device array; 2) cutting a nanometer gap of 1-10nm in a graphene molecular device; and 3) connecting a designed DNAzyme sequence into the nanometer gap to obtain the DNAzyme monomolecular connection device. An electrical signal detection with heavy metal ion binding and identification is carried out byutilizing the manufactured DNAzyme monomolecular connection device, meanwhile, the interference factors are excluded; the heavy metal ions are tested in sensitivity and the like on the connection device; and the measurement conditions are determined according to the test results in the above steps, and the heavy metal ions are detected on the connection device. According to the invention, the high-sensitivity detection of the heavy metal can be realized through the electricity signal by utilizing the functionalized graphene electrode molecular device. The method is of great significance in detecting a trace amount of the heavy metal in the environment.
Owner:PEKING UNIV

Detecting method for divalent mercury ions

The invention discloses a detecting method for divalent mercury ions. The principle for detecting mercury ions by using the method is as follows: a single-chain DNA (Deoxyribose Nucleic Acid) molecule B modified by fluorescein contains a sequence which is complementary with a sequence of a DNA catching needle (a single-chain DNA molecule A) fixed on the surface of a probe, and also contains a T-T base pair mismatch structure which can be combined with the divalent mercury ions. During detection, the single-chain DNA molecule B modified by the fluorescein and the mercury ions are simultaneously input to the surface of an optical fiber sensor probe for evanescent waves, and the divalent mercury ions are combined with the single-chain DNA molecule B modified by the fluorescein by the DNA catching needle in a competition way. The more the concentration of the divalent mercury ions is, the fewer the single-chain DNA molecule B modified by the fluorescein and combined with the DNA catching needle on the optical fiber sensor probe for evanescent waves is, so that a fluorescence intensity signal detected by an optical detecting platform for evanescent waves is weaker. An effective means is provided for the rapid on-site and real-time detection of heavy metal mercury ions in the fields of foods, medicines and environments.
Owner:BEIJING INST OF COLLABORATIVE INNOVATION +1
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